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Integrated Training in Dry Eye Disease Drug Development (IT-DED3)

Deliverables

All ESRs are recruited

All ESRs are recruited at this timepoint

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Publications

Hyaluronic acid and Chondroitin sulfate from marine and terrestrial sources: Extraction and purification methods

Author(s): Maha M. Abdallah, Naiara Fernández, Ana A. Matias, Maria do Rosário Bronze
Published in: Carbohydrate Polymers, Issue 243, 2020, Page(s) 116441, ISSN 0144-8617
DOI: 10.1016/j.carbpol.2020.116441

Topical treatment with a mu opioid receptor agonist alleviates corneal allodynia and corneal nerve sensitization in mice

Author(s): Fanny Joubert, Adrian Guerrero-Moreno, Darine Fakih, Elodie Reboussin, Claire Gaveriaux-Ruff, Maria Carmen Acosta, Juana Gallar, José Alain Sahel, Laurence Bodineau, Christophe Baudouin, William Rostène, Stéphane Mélik-Parsadaniantz, Annabelle Réaux-Le Goazigo
Published in: Biomedicine & Pharmacotherapy, Issue 132, 2020, Page(s) 110794, ISSN 0753-3322
DOI: 10.1016/j.biopha.2020.110794

Ocular Delivery of Polyphenols: Meeting the Unmet Needs

Author(s): Luna Krstić, María J. González-García, Yolanda Diebold
Published in: Molecules, Issue 26/2, 2021, Page(s) 370, ISSN 1420-3049
DOI: 10.3390/molecules26020370

Morphological and Functional Changes of Corneal Nerves and Their Contribution to Peripheral and Central Sensory Abnormalities

Author(s): Adrian Guerrero-Moreno, Christophe Baudouin, Stéphane Melik Parsadaniantz, Annabelle Réaux-Le Goazigo
Published in: Frontiers in Cellular Neuroscience, Issue 14, 2020, ISSN 1662-5102
DOI: 10.3389/fncel.2020.610342

Capsazepine decreases corneal pain syndrome in severe dry eye disease

Author(s): Darine Fakih, Adrian Guerrero-Moreno, Christophe Baudouin, Annabelle Réaux-Le Goazigo, Stéphane Mélik Parsadaniantz
Published in: Journal of Neuroinflammation, Issue 18/1, 2021, ISSN 1742-2094
DOI: 10.1186/s12974-021-02162-7

Deep learning-based automatic meibomian gland segmentation and morphology assessment in infrared meibography

Author(s): Md Asif Khan Setu, Jens Horstmann, Stefan Schmidt, Michael E. Stern, Philipp Steven
Published in: Scientific Reports, Issue 11/1, 2021, ISSN 2045-2322
DOI: 10.1038/s41598-021-87314-8

Corneal Nerve Abnormalities in Painful Dry Eye Disease Patients

Author(s): Adrian Guerrero-Moreno, Hong Liang, Nathan Moreau, Jade Luzu, Ghislaine Rabut, Stéphane Melik Parsadaniantz, Antoine Labbé, Christophe Baudouin, Annabelle Réaux-Le Goazigo
Published in: Biomedicines, Issue 9/10, 2021, Page(s) 1424, ISSN 2227-9059
DOI: 10.3390/biomedicines9101424

Olive Pomace Phenolic Compounds Stability and Safety Evaluation: From Raw Material to Future Ophthalmic Applications

Author(s): Nikolaos Katsinas, Amalia Enríquez-de-Salamanca, Andreia Bento da Silva, Maria Rosário Bronze, Soraya Rodríguez-Rojo
Published in: Molecules, Issue 26/19, 2021, Page(s) 6002, ISSN 1420-3049
DOI: 10.3390/molecules26196002

How does chronic dry eye shape peripheral and central nociceptive systems?

Author(s): Annabelle Réaux-Le Goazigo, Adrian Guerrero-Moreno, Darine Fakih, StéphaneMelik Parsadaniantz
Published in: Neural Regeneration Research, Issue 16/2, 2021, Page(s) 306, ISSN 1673-5374
DOI: 10.4103/1673-5374.290895

Olive Pomace Phenolic Compounds and Extracts Can Inhibit Inflammatory- and Oxidative-Related Diseases of Human Ocular Surface Epithelium

Author(s): Nikolaos Katsinas, Soraya Rodríguez-Rojo, Amalia Enríquez-de-Salamanca
Published in: Antioxidants, Issue 10/7, 2021, Page(s) 1150, ISSN 2076-3921
DOI: 10.3390/antiox10071150

Physicochemical Characterization and Simulation of the Solid–Liquid Equilibrium Phase Diagram of Terpene-Based Eutectic Solvent Systems

Author(s): Maha M. Abdallah, Simon Müller, Andrés González de Castilla, Pavel Gurikov, Ana A. Matias, Maria do Rosário Bronze, Naiara Fernández
Published in: Molecules, Issue 26/6, 2021, Page(s) 1801, ISSN 1420-3049
DOI: 10.3390/molecules26061801

A novel serine protease inhibitor as potential treatment for dry eye syndrome and ocular inflammation

Author(s): Cedric Joossen, Adrienn Baán, Carlos Moreno-Cinos, Jurgen Joossens, Nathalie Cools, Ellen Lanckacker, Lieve Moons, Kim Lemmens, Anne-Marie Lambeir, Erik Fransen, Peter Delputte, Guy Caljon, Pieter Van Der Veken, Louis Maes, Ingrid De Meester, Filip Kiekens, Koen Augustyns, Paul Cos
Published in: Scientific Reports, Issue 10/1, 2020, ISSN 2045-2322
DOI: 10.1038/s41598-020-74159-w

Pressurized Liquid Extraction Optimization from Supercritical Defatted Olive Pomace: A Green and Selective Phenolic Extraction Process

Author(s): Nikolaos Katsinas, Andreia Bento da Silva, Amalia Enríquez-de-Salamanca, Naiara Fernández, Maria Rosário Bronze, Soraya Rodríguez-Rojo
Published in: ACS Sustainable Chemistry & Engineering, 2021, ISSN 2168-0485
DOI: 10.1021/acssuschemeng.0c09426