Targeting the metabolism-immune system connections in Cancer

Project Information

META-CAN

Grant agreement ID: 766214

DOI 10.3030/766214

Project closed

EC signature date 10 August 2017

Start date 1 September 2017

End date 31 August 2021

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost € 3 831 957,72

EU contribution € 3 831 957,72

Coordinated by

FUNDACIO INSTITUT D'INVESTIGACIO BIOMEDICA DE BELLVITGE
Spain

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Other (9)

First Scientific Training

First Workshop

Fourth Scientific Training

Conference

Third Complementary skills Training
Second Scientific Training

Second Workshop

Fourth Complementary skills training

Fourth Complementary skills Training

Third Scientific Training

Third Workshop

First Complementary skills training

First complementary skills Training

Second complementary skills training

Second Complementary skills training

ESR recruitment start

Websites, patent fillings, videos etc. (2)

Website
Social Media accounts

Social Media Accounts

Publications

Peer reviewed articles (14)

EVT‐701 is a novel selective and safe mitochondrial complex 1 inhibitor with potent anti‐tumor activity in models of solid cancers

Author(s): Raquel Luna Yolba, Virgile Visentin, Caroline Hervé, Johanna Chiche, Jean‐Ehrland Ricci, Jérôme Méneyrol, Michaël R. Paillasse, Nathalie Alet
Published in: Pharmacology Research & Perspectives, Issue 9/5, 2021, ISSN 2052-1707
Publisher: British Pharmacological Society
DOI: 10.1002/prp2.854

Macrophage-derived glutamine boosts satellite cells and muscle regeneration

Author(s): Min Shang, Federica Cappellesso, Ricardo Amorim, Jens Serneels, Federico Virga, Guy Eelen, Stefania Carobbio, Melvin Y. Rincon, Pierre Maechler, Katrien De Bock, Ping-Chih Ho, Marco Sandri, Bart Ghesquière, Peter Carmeliet, Mario Di Matteo, Emanuele Berardi, Massimiliano Mazzone
Published in: Nature, Issue 587/7835, 2020, Page(s) 626-631, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-020-2857-9

Efficacy of CDK4/6 inhibitors in preclinical models of malignant pleural mesothelioma

Author(s): Elisabet Aliagas, Ania Alay, Maria Martínez-Iniesta, Miguel Hernández-Madrigal, David Cordero, Mireia Gausachs, Eva Pros, Maria Saigí, Sara Busacca, Annabel J. Sharkley, Alan Dawson, Ramón Palmero, José C. Ruffinelli, Susana Padrones, Samantha Aso, Ignacio Escobar, Ricard Ramos, Roger Llatjós, August Vidal, Eduard Dorca, Mar Varela, Montse Sánchez-Céspedes, Dean Fennell, Cristina Muñoz-Pi
Published in: British Journal of Cancer, 2021, ISSN 0007-0920
Publisher: Nature Publishing Group
DOI: 10.1038/s41416-021-01547-y

Disrupting Mitochondrial Electron Transfer Chain Complex I Decreases Immune Checkpoints in Murine and Human Acute Myeloid Leukemic Cells

Author(s): Raquel Luna-Yolba, Justine Marmoiton, Véronique Gigo, Xavier Marechal, Emeline Boet, Ambrine Sahal, Nathalie Alet, Ifat Abramovich, Eyal Gottlieb, Virgile Visentin, Michael R. Paillasse, Jean-Emmanuel Sarry
Published in: Cancers, Issue 13/14, 2021, Page(s) 3499, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13143499

Physiological impact of in vivo stable isotope tracing on cancer metabolism

Author(s): Manuel Grima-Reyes, Adriana Martinez-Turtos, Ifat Abramovich, Eyal Gottlieb, Johanna Chiche, Jean-Ehrland Ricci
Published in: Molecular Metabolism, 2021, Page(s) 101294, ISSN 2212-8778
Publisher: Elsevier GmbH
DOI: 10.1016/j.molmet.2021.101294

Hematopoietic versus Solid Cancers and T Cell Dysfunction: Looking for Similarities and Distinctions

Author(s): Chiara Montironi, Cristina Muñoz-Pinedo, Eric Eldering
Published in: Cancers, Issue 13/2, 2021, Page(s) 284, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13020284

Metabolic traits ruling the specificity of the immune response in different cancer types

Author(s): Nina C Flerin, Federica Cappellesso, Samantha Pretto, Massimiliano Mazzone
Published in: Current Opinion in Biotechnology, Issue 68, 2021, Page(s) 124-143, ISSN 0958-1669
Publisher: Elsevier BV
DOI: 10.1016/j.copbio.2020.10.011

Metabolic adaptation of acute lymphoblastic leukemia to the central nervous system microenvironment depends on stearoyl-CoA desaturase

Author(s): Angela Maria Savino, Sara Isabel Fernandes, Orianne Olivares, Anna Zemlyansky, Antony Cousins, Elke K. Markert, Shani Barel, Ifat Geron, Liron Frishman, Yehudit Birger, Cornelia Eckert, Sergey Tumanov, Gillian MacKay, Jurre J. Kamphorst, Pawel Herzyk, Jonatan Fernández-García, Ifat Abramovich, Inbal Mor, Michela Bardini, Ersilia Barin, Sudha Janaki-Raman, Justin R. Cross, Michael G. Kharas, Eyal
Published in: Nature Cancer, Issue 1/10, 2020, Page(s) 998-1009, ISSN 2662-1347
Publisher: Nature Publishing Group
DOI: 10.1038/s43018-020-00115-2

GAPDH Expression Predicts the Response to R-CHOP, the Tumor Metabolic Status, and the Response of DLBCL Patients to Metabolic Inhibitors

Author(s): Johanna Chiche, Julie Reverso-Meinietti, Annabelle Mouchotte, Camila Rubio-Patiño, Rana Mhaidly, Elodie Villa, Jozef P. Bossowski, Emma Proics, Manuel Grima-Reyes, Agnès Paquet, Konstantina Fragaki, Sandrine Marchetti, Josette Briere, Damien Ambrosetti, Jean-François Michiels, Thierry Jo Molina, Christiane Copie-Bergman, Jacqueline Lehmann-Che, Isabelle Peyrottes, Frederic Peyrade, Eric de Kerv
Published in: Cell Metabolism, 2019, ISSN 1550-4131
Publisher: Cell Press
DOI: 10.1016/j.cmet.2019.02.002

Inferring new relations between medical entities using literature curated term co-occurrences

Author(s): Adam Spiro, Jonatan Fernández García, Chen Yanover
Published in: JAMIA Open, 2019, ISSN 2574-2531
Publisher: Oxford Academic
DOI: 10.1093/jamiaopen/ooz022

Impact of Immunometabolism on Cancer Metastasis: A Focus on T Cells and Macrophages

Author(s): Nina C. Flerin, Sotiria Pinioti, Alessio Menga, Alessandra Castegna, Massimiliano Mazzone
Published in: Cold Spring Harbor Perspectives in Medicine, 2019, Page(s) a037044, ISSN 2157-1422
Publisher: Cold Spring Harbor Laboratory Press
DOI: 10.1101/cshperspect.a037044

Starvation and antimetabolic therapy promote cytokine release and recruitment of immune cells

Author(s): Franziska Püschel, Francesca Favaro, Jaime Redondo-Pedraza, Estefanía Lucendo, Raffaella Iurlaro, Sandrine Marchetti, Blanca Majem, Eric Eldering, Ernest Nadal, Jean-Ehrland Ricci, Eric Chevet, Cristina Muñoz-Pinedo
Published in: Proceedings of the National Academy of Sciences, Issue 117/18, 2020, Page(s) 9932-9941, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.1913707117

LOXL2 promotes oncogenic progression in alveolar rhabdomyosarcoma independently of its catalytic activity

Author(s): Olga Almacellas-Rabaiget, Paola Monaco, Juan Huertas-Martinez, Silvia García-Monclús, Mariona Chicón-Bosch, Susana Maqueda-Marcos, Isabel Fabra-Heredia, David Herrero-Martín, Santiago Rello-Varona, Enrique de Alava, Roser López-Alemany, Paloma H. Giangrande, Oscar M. Tirado
Published in: Cancer Letters, Issue 474, 2020, Page(s) 1-14, ISSN 0304-3835
Publisher: Elsevier BV
DOI: 10.1016/j.canlet.2019.12.040

Macrophage miR-210 induction and metabolic reprogramming in response to pathogen interaction boost life-threatening inflammation

Author(s): Federico Virga, Federica Cappellesso, Benoit Stijlemans, Anne-Theres Henze, Rosa Trotta, Jonas Van Audenaerde, Ananda S. Mirchandani, Manuel A. Sanchez-Garcia, Jolien Vandewalle, Francesca Orso, Carla Riera-Domingo, Alberto Griffa, Cristina Ivan, Evelien Smits, Damya Laoui, Fabio Martelli, Lies Langouche, Greet Van den Berghe, Olivier Feron, Bart Ghesquière, Hans Prenen, Claude Libert, Sarah R. W
Published in: Science Advances, Issue 7/19, 2021, Page(s) eabf0466, ISSN 2375-2548
Publisher: American Association for the Advancement of Science
DOI: 10.1126/sciadv.abf0466