Targeting the metabolism-immune system connections in Cancer

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Publikacje

EVT‐701 is a novel selective and safe mitochondrial complex 1 inhibitor with potent anti‐tumor activity in models of solid cancers

Autorzy: Raquel Luna Yolba, Virgile Visentin, Caroline Hervé, Johanna Chiche, Jean‐Ehrland Ricci, Jérôme Méneyrol, Michaël R. Paillasse, Nathalie Alet
Opublikowane w: Pharmacology Research & Perspectives, Numer 9/5, 2021, ISSN 2052-1707
Wydawca: British Pharmacological Society
DOI: 10.1002/prp2.854

Macrophage-derived glutamine boosts satellite cells and muscle regeneration

Autorzy: Min Shang, Federica Cappellesso, Ricardo Amorim, Jens Serneels, Federico Virga, Guy Eelen, Stefania Carobbio, Melvin Y. Rincon, Pierre Maechler, Katrien De Bock, Ping-Chih Ho, Marco Sandri, Bart Ghesquière, Peter Carmeliet, Mario Di Matteo, Emanuele Berardi, Massimiliano Mazzone
Opublikowane w: Nature, Numer 587/7835, 2020, Strona(/y) 626-631, ISSN 0028-0836
Wydawca: Nature Publishing Group
DOI: 10.1038/s41586-020-2857-9

Efficacy of CDK4/6 inhibitors in preclinical models of malignant pleural mesothelioma

Autorzy: Elisabet Aliagas, Ania Alay, Maria Martínez-Iniesta, Miguel Hernández-Madrigal, David Cordero, Mireia Gausachs, Eva Pros, Maria Saigí, Sara Busacca, Annabel J. Sharkley, Alan Dawson, Ramón Palmero, José C. Ruffinelli, Susana Padrones, Samantha Aso, Ignacio Escobar, Ricard Ramos, Roger Llatjós, August Vidal, Eduard Dorca, Mar Varela, Montse Sánchez-Céspedes, Dean Fennell, Cristina Muñoz-Pi
Opublikowane w: British Journal of Cancer, 2021, ISSN 0007-0920
Wydawca: Nature Publishing Group
DOI: 10.1038/s41416-021-01547-y

Disrupting Mitochondrial Electron Transfer Chain Complex I Decreases Immune Checkpoints in Murine and Human Acute Myeloid Leukemic Cells

Autorzy: Raquel Luna-Yolba, Justine Marmoiton, Véronique Gigo, Xavier Marechal, Emeline Boet, Ambrine Sahal, Nathalie Alet, Ifat Abramovich, Eyal Gottlieb, Virgile Visentin, Michael R. Paillasse, Jean-Emmanuel Sarry
Opublikowane w: Cancers, Numer 13/14, 2021, Strona(/y) 3499, ISSN 2072-6694
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13143499

Physiological impact of in vivo stable isotope tracing on cancer metabolism

Autorzy: Manuel Grima-Reyes, Adriana Martinez-Turtos, Ifat Abramovich, Eyal Gottlieb, Johanna Chiche, Jean-Ehrland Ricci
Opublikowane w: Molecular Metabolism, 2021, Strona(/y) 101294, ISSN 2212-8778
Wydawca: Elsevier GmbH
DOI: 10.1016/j.molmet.2021.101294

Hematopoietic versus Solid Cancers and T Cell Dysfunction: Looking for Similarities and Distinctions

Autorzy: Chiara Montironi, Cristina Muñoz-Pinedo, Eric Eldering
Opublikowane w: Cancers, Numer 13/2, 2021, Strona(/y) 284, ISSN 2072-6694
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13020284

Metabolic traits ruling the specificity of the immune response in different cancer types

Autorzy: Nina C Flerin, Federica Cappellesso, Samantha Pretto, Massimiliano Mazzone
Opublikowane w: Current Opinion in Biotechnology, Numer 68, 2021, Strona(/y) 124-143, ISSN 0958-1669
Wydawca: Elsevier BV
DOI: 10.1016/j.copbio.2020.10.011

Metabolic adaptation of acute lymphoblastic leukemia to the central nervous system microenvironment depends on stearoyl-CoA desaturase

Autorzy: Angela Maria Savino, Sara Isabel Fernandes, Orianne Olivares, Anna Zemlyansky, Antony Cousins, Elke K. Markert, Shani Barel, Ifat Geron, Liron Frishman, Yehudit Birger, Cornelia Eckert, Sergey Tumanov, Gillian MacKay, Jurre J. Kamphorst, Pawel Herzyk, Jonatan Fernández-García, Ifat Abramovich, Inbal Mor, Michela Bardini, Ersilia Barin, Sudha Janaki-Raman, Justin R. Cross, Michael G. Kharas, Eyal
Opublikowane w: Nature Cancer, Numer 1/10, 2020, Strona(/y) 998-1009, ISSN 2662-1347
Wydawca: Nature Publishing Group
DOI: 10.1038/s43018-020-00115-2

GAPDH Expression Predicts the Response to R-CHOP, the Tumor Metabolic Status, and the Response of DLBCL Patients to Metabolic Inhibitors

Autorzy: Johanna Chiche, Julie Reverso-Meinietti, Annabelle Mouchotte, Camila Rubio-Patiño, Rana Mhaidly, Elodie Villa, Jozef P. Bossowski, Emma Proics, Manuel Grima-Reyes, Agnès Paquet, Konstantina Fragaki, Sandrine Marchetti, Josette Briere, Damien Ambrosetti, Jean-François Michiels, Thierry Jo Molina, Christiane Copie-Bergman, Jacqueline Lehmann-Che, Isabelle Peyrottes, Frederic Peyrade, Eric de Kerv
Opublikowane w: Cell Metabolism, 2019, ISSN 1550-4131
Wydawca: Cell Press
DOI: 10.1016/j.cmet.2019.02.002

Inferring new relations between medical entities using literature curated term co-occurrences

Autorzy: Adam Spiro, Jonatan Fernández García, Chen Yanover
Opublikowane w: JAMIA Open, 2019, ISSN 2574-2531
Wydawca: Oxford Academic
DOI: 10.1093/jamiaopen/ooz022

Impact of Immunometabolism on Cancer Metastasis: A Focus on T Cells and Macrophages

Autorzy: Nina C. Flerin, Sotiria Pinioti, Alessio Menga, Alessandra Castegna, Massimiliano Mazzone
Opublikowane w: Cold Spring Harbor Perspectives in Medicine, 2019, Strona(/y) a037044, ISSN 2157-1422
Wydawca: Cold Spring Harbor Laboratory Press
DOI: 10.1101/cshperspect.a037044

Starvation and antimetabolic therapy promote cytokine release and recruitment of immune cells

Autorzy: Franziska Püschel, Francesca Favaro, Jaime Redondo-Pedraza, Estefanía Lucendo, Raffaella Iurlaro, Sandrine Marchetti, Blanca Majem, Eric Eldering, Ernest Nadal, Jean-Ehrland Ricci, Eric Chevet, Cristina Muñoz-Pinedo
Opublikowane w: Proceedings of the National Academy of Sciences, Numer 117/18, 2020, Strona(/y) 9932-9941, ISSN 0027-8424
Wydawca: National Academy of Sciences
DOI: 10.1073/pnas.1913707117

LOXL2 promotes oncogenic progression in alveolar rhabdomyosarcoma independently of its catalytic activity

Autorzy: Olga Almacellas-Rabaiget, Paola Monaco, Juan Huertas-Martinez, Silvia García-Monclús, Mariona Chicón-Bosch, Susana Maqueda-Marcos, Isabel Fabra-Heredia, David Herrero-Martín, Santiago Rello-Varona, Enrique de Alava, Roser López-Alemany, Paloma H. Giangrande, Oscar M. Tirado
Opublikowane w: Cancer Letters, Numer 474, 2020, Strona(/y) 1-14, ISSN 0304-3835
Wydawca: Elsevier BV
DOI: 10.1016/j.canlet.2019.12.040

Macrophage miR-210 induction and metabolic reprogramming in response to pathogen interaction boost life-threatening inflammation

Autorzy: Federico Virga, Federica Cappellesso, Benoit Stijlemans, Anne-Theres Henze, Rosa Trotta, Jonas Van Audenaerde, Ananda S. Mirchandani, Manuel A. Sanchez-Garcia, Jolien Vandewalle, Francesca Orso, Carla Riera-Domingo, Alberto Griffa, Cristina Ivan, Evelien Smits, Damya Laoui, Fabio Martelli, Lies Langouche, Greet Van den Berghe, Olivier Feron, Bart Ghesquière, Hans Prenen, Claude Libert, Sarah R. W
Opublikowane w: Science Advances, Numer 7/19, 2021, Strona(/y) eabf0466, ISSN 2375-2548
Wydawca: American Association for the Advancement of Science
DOI: 10.1126/sciadv.abf0466

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