Deliverables Documents, reports (22) Report on online activities organization This deliverable will report the online training activities organization (M9, M18, M27, M36, M45) Report on the targeted in vivo assays Report on the targeted in vivo assays Leaflets Leaflets of the project (M3 and M24) Report on the multimedia environmental contamination modelling This deliverable will report the results of the multimedia environmental contamination modelling Report on the genome-wide profiling of the collected biosamples This deliverable will report the genomewide profiling results of the collected biosamples Report on the overall project methodology This deliverable will outline the overall project methodology This will include the overall synthesis of the different scientific WPs aiming at providing the overall methodological approach of identifying the causal link between environmental exposure and neurodevelopmental disorders Report on workshop outcome synthesis - overall WP5 methodology This deliverable will summarize the training workshop outcomes on the overall WP5 methodology Report on transcriptomics and metabolomics analysis of the collected biosamples This deliverable will report the results of transcriptomics and metabolomics analysis of the collected biosamples Biostatistics methods for genomic- environment wide associations This deliverble will report big data analytics methods for genomeenvironmentwide associations with adverse health outcomes Training material on S/T and soft skills Training material on S/T and soft skills (M6, M10, M14, M18, M45) Syllabus for structured training courses This deliverable will report the syllabus for structured training courses Report on synthesis workshop outcome - overall WP4 methodology This deliverable will summarize the training workshop outcomes on the overall WP4 methodology Report on the collation of HBM data and exposure biomarkers analysis This deliverable will summarize HBM data collated and the results of the analysis of exposure biomarkers Report on workshop outcome synthesis - overall WP6 methodology This deliverable will summarize the training workshop outcomes on the overall WP6 methodology Development of infrastructure for HBM (including omics) and environmental/exposure data assimilation This deliverable will decribe the developed data infrastructure for HBM including omics and environmentalexposure data assimilation Report on workshop outcome synthesis - overall WP7 methodology This deliverable will summarize the training workshop outcomes on the overall WP7 methodology Report on the targeted in vitro assays This deliverable will report the targeted in vitro assays results Report on the analysis of environmental samples from different media This report summarizes the analysis of environmental samples from different media Report on generic PBBK model taking into account mixtures interaction This deliverable will describe the developed generic PBBK model which will take into account mixtures interaction Report on the sensors and agent based modeling for exposure assessment This deliverable will report results of the sensors and agent based modeling for exposure assessment Report on the functional integration of different omics results using bioinformatics tools for the development of AOPs for neurodevelopmental disorders This deliverable will report the functional integration of different omics results using bioinformatics tools for the development of AOPs for neurodevelopmental disorders Newsletters Project newsletters issued at M12, M24, M36 Websites, patent fillings, videos etc. (1) Website Website of the projet Other (2) Application and selection process – overall recruitment Application and selection process – overall recruitment Final conference This deliverable is the final project conference M54 Publications Peer reviewed articles (31) Impact of Methylmercury and Other Heavy Metals Exposure on Neurocognitive Function in Children Aged 7 Years: Study Protocol of the Follow-up Author(s): Vecchi Brumatti L, Rosolen V, Mariuz M, Piscianz E, Valencic E, Bin M, Athanasakis E, D'Adamo P, Fragkiadoulaki E, Calamandrei G, Dinçkol Ö, Barbone F, Ronfani L. Published in: Journal of Epidemiology, 2021, ISSN 0917-5040 Publisher: Tokyo University of Agriculture DOI: 10.2188/jea.je20190284 Demonstrating the use of a framework for risk-informed decisions with stakeholder engagement through case studies for NORM and nuclear legacy sites Author(s): Konti´c Branko; Black Paul; French Simon; Paulley Alan; Zhu Ming; Yankovich Tamara; Webster Michael; Pepin Stephane; Bizjak Tine; Bohanec Marko Published in: Journal of Radiological Protection, Issue 1, 2022, ISSN 0952-4746 Publisher: Institute of Physics Publishing DOI: 10.1088/1361-6498/ac5816 Low-Level Lead Exposure During Development Differentially Affects Neurobehavioral responses in Male and Female Mouse Offspring: A Longitudinal Study Author(s): Dinçkol Ö. Fuentes B., Tartaglione A.M., Pino A., Ricceri L., Calamandrei G Published in: Neurotoxicology, 2022, ISSN 0161-813X Publisher: Elsevier BV DOI: 10.1016/j.neuro.2022.05.007 A systems toxicology approach to compare the heavy metal mixtures (Pb, As, MeHg) impact in neurodegenerative diseases Author(s): Venkatanaidu Karri (PhD); Marta Schuhmacher Professor; Vikas Kumar (PhD) Published in: Food and Chemical Toxicology, Issue 139, 2020, ISSN 0278-6915 Publisher: Elsevier BV DOI: 10.1016/j.fct.2020.111257 Neurodevelopmental exposome: The effect of in utero co-exposure to heavy metals and phthalates on child neurodevelopment Author(s): Denis A. Sarigiannis, Nafsika Papaioannou, Evangelos Handakas, Ourania Anesti, Kinga Polanska, Woijcek Hanke, Athanasios Salifoglou, Catherine Gabriel, Spyros Karakitsios Published in: Environmental Research, Issue 197, 2021, ISSN 0013-9351 Publisher: Academic Press DOI: 10.1016/j.envres.2021.110949 Changes of organochlorine compound concentrations in maternal serum during pregnancy and comparison to serum cord blood composition Author(s): Eva Junqué; Sergi Garcia; María Ángeles Martínez; Joaquim Rovira; Marta Schuhmacher; Joan O. Grimalt Published in: Environmental Research, Issue Vol.182, 2020, ISSN 0013-9351 Publisher: Academic Press DOI: 10.1016/j.envres.2019.108994 Exposure of men and lactating women to environmental phenols, phthalates, and DINCH Author(s): Agneta A. Runkel; Darja Mazej; Janja Snoj Tratnik; žiga Tkalec; Tina Kosjek; Milena Horvat Published in: Chemosphere, Issue Volume 286, Part 3, 2022, ISSN 0045-6535 Publisher: Pergamon Press Ltd. DOI: 10.1016/j.chemosphere.2021.131858 Urinary phthalate concentrations in the slovenian population: An attempt to exposure assessment of family units Author(s): Agneta A. Runkel, Janja Snoj-Tratnik, Darja Mazej, Milena Horvat Published in: Environmental Research, Issue 186, 2020, Page(s) 109548, ISSN 0013-9351 Publisher: Academic Press DOI: 10.1016/j.envres.2020.109548 Practical Opportunities to Improve the Impact of Health Risk Assessment on Environmental and Public Health Decisions Author(s): Bizjak, Tine; Kontić, Davor; Kontić, Branko Published in: International Journal of Environmental Research and Public Health, Issue Vol. 19, 2022, ISSN 1661-7827 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/ijerph19074200 EDC-induced mechanisms of immunotoxicity: a systematic review Author(s): Oscar Sabuz Vidal; Deepika Deepika; Marta Schuhmacher; Vikas Kumar Published in: CRITICAL REVIEWS IN TOXICOLOGY, Issue VOL. 51, NO. 7, 2021, Page(s) 634–652, ISSN 1040-8444 Publisher: Taylor & Francis DOI: 10.1080/10408444.2021.2009438 Risk Assessment of Perfluorooctane Sulfonate (PFOS) using Dynamic Age Dependent Physiologically based Pharmacokinetic Model (PBPK) across Human Lifetime Author(s): Deepika Deepika, Raju Prasad Sharma, Marta Schuhmacher. Vikas Kumar Published in: Environmental Research, Issue 199, 2021, ISSN 0013-9351 Publisher: Academic Press DOI: 10.1016/j.envres.2021.111287 An Integrative Translational Framework for Chemical Induced Neurotoxicity- A Systematic Review Author(s): Deepika Deepika, Raju Prasad Sharma, Marta Schuhmacher and Vikas Kumar Published in: Critical Reviews in Toxicology, Issue VOL. 50, NO. 5, 2020, Page(s) 424–438, ISSN 1040-8444 Publisher: Taylor & Francis DOI: 10.1080/10408444.2020.1763253 Organohalogens: A persisting burden in Slovenia? Author(s): Agneta A. Runkel; Boštjan Križanec; Eva Lipičar; Mojca Baskar; Vesna Hrženjak; Zdenka Cencič Kodba; Lijana Kononenko; Tjaša Kanduč; Darja Mazej; Janja Snoj Tratnik; Milena Horvat Published in: Environmental Research, Issue 198, 2021, ISSN 0013-9351 Publisher: Academic Press DOI: 10.1016/j.envres.2021.111224 Impact of Contaminants on Microbiota: Linking the Gut–Brain Axis with Neurotoxicity Author(s): Jordina Balaguer-Trias; Deepika Deepika; Marta Schuhmacher; Vikas Kumar Published in: International Journal of Environmental Research and Public Health, Issue 19, 2022, ISSN 1661-7827 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/ijerph19031368 Auditing in addition to compliance monitoring: a way to improve public health Author(s): Tine Bizjak, Branko Kontić Published in: International Journal of Public Health, 2019, ISSN 1661-8556 Publisher: Birkhauser Verlag DOI: 10.1007/s00038-019-01291-4 Mother-child transfer rates of organohalogen compounds up to four years of age Author(s): Mercè Garí, Joan O. Grimalt, Esther Vizcaino, Adonina Tardón, Ana Fernández-Somoano Published in: Environment International, Issue 133, 2019, Page(s) 105241, ISSN 0160-4120 Publisher: Pergamon Press Ltd. DOI: 10.1016/j.envint.2019.105241 Influence of maternal and sociodemographic characteristics on the accumulation of organohalogen compounds in Argentinian women. The EMASAR study Author(s): Natalia Bravo, Solrunn Hansen, Inger Økland, Mercè Garí, Marisa V. Álvarez, Silvina Matiocevich, Jon-Øyvind Odland, Joan O. Grimalt Published in: Environmental Research, Issue 158, 2017, Page(s) 759-767, ISSN 0013-9351 Publisher: Academic Press DOI: 10.1016/j.envres.2017.07.033 Mother/child organophosphate and pyrethroid distributions Author(s): Natalia Bravo, Joan O. Grimalt, Darja Mazej, Janja Snoj Tratnik, Dimosthenis Andreas Sarigiannis, Milena Horvat Published in: Environment International, Issue 134, 2020, Page(s) 105264, ISSN 0160-4120 Publisher: Pergamon Press Ltd. DOI: 10.1016/j.envint.2019.105264 Origin of polycyclic aromatic hydrocarbons and other organic pollutants in the air particles of subway stations in Barcelona Author(s): Barend L. van Drooge, Raimon M. Prats, Cristina Reche, MariCruz Minguillón, Xavier Querol, Joan O. Grimalt, Teresa Moreno Published in: Science of The Total Environment, Issue 642, 2018, Page(s) 148-154, ISSN 0048-9697 Publisher: Elsevier BV DOI: 10.1016/j.scitotenv.2018.06.032 Drivers of the accumulation of mercury and organochlorine pollutants in Mediterranean lean fish and dietary significance Author(s): Eva Junqué, Mercè Garí, Rosa Maria Llull, Joan O. Grimalt Published in: Science of The Total Environment, Issue 634, 2018, Page(s) 170-180, ISSN 0048-9697 Publisher: Elsevier BV DOI: 10.1016/j.scitotenv.2018.03.335 Risk characterization of bisphenol-A in the Slovenian population starting from human biomonitoring data Author(s): Dimosthenis A. Sarigiannis, Janja Snoj Tratnik, Darja Mazej, Tina Kosjek, Ester Heath, Milena Horvat, Ourania Anesti, Spyros P. Karakitsios Published in: Environmental Research, Issue 170, 2019, Page(s) 293-300, ISSN 0013-9351 Publisher: Academic Press DOI: 10.1016/j.envres.2018.12.056 Analysis of metabolites of organophosphate and pyrethroid pesticides in human urine from urban and agricultural populations (Catalonia and Galicia) Author(s): Mercè Garí, Yolanda González-Quinteiro, Natalia Bravo, Joan O. Grimalt Published in: Science of The Total Environment, Issue 622-623, 2018, Page(s) 526-533, ISSN 0048-9697 Publisher: Elsevier BV DOI: 10.1016/j.scitotenv.2017.11.355 Influence of electronic cigarette vaping on the composition of indoor organic pollutants, particles, and exhaled breath of bystanders Author(s): Barend L. van Drooge, Esther Marco, Noemi Perez, Joan O. Grimalt Published in: Environmental Science and Pollution Research, Issue 26/5, 2019, Page(s) 4654-4666, ISSN 0944-1344 Publisher: Springer Verlag DOI: 10.1007/s11356-018-3975-x Urinary metabolites of organophosphate and pyrethroid pesticides in children from an Italian cohort (PHIME, Trieste) Author(s): Natalia Bravo, Joan O. Grimalt, Beatrice Bocca, Anna Pino, Maura Bin, Liza Vecchi Brumatti, Valentina Rosolen, Fabio Barbone, Luca Ronfani, Alessandro Alimonti, Gemma Calamandrei Published in: Environmental Research, Issue 176, 2019, Page(s) 108508, ISSN 0013-9351 Publisher: Academic Press DOI: 10.1016/j.envres.2019.05.039 Drivers of maternal accumulation of organohalogen pollutants in Arctic areas (Chukotka, Russia) and 4,4′-DDT effects on the newborns Author(s): Natalia Bravo, Joan O. Grimalt, Max Chashchin, Valery P. Chashchin, Jon-Øyvind Odland Published in: Environment International, Issue 124, 2019, Page(s) 541-552, ISSN 0160-4120 Publisher: Pergamon Press Ltd. DOI: 10.1016/j.envint.2019.01.049 Atmospheric pattern of volatile organochlorine compounds and hexachlorobenzene in the surroundings of a chlor-alkali plant Author(s): Barend L. van Drooge, Esther Marco, Joan O. Grimalt Published in: Science of The Total Environment, Issue 628-629, 2018, Page(s) 782-790, ISSN 0048-9697 Publisher: Elsevier BV DOI: 10.1016/j.scitotenv.2018.02.088 Organophosphate metabolite concentrations in maternal urine during pregnancy Author(s): Natalia Bravo; Soraya Peralta; Joan O. Grimalt; Maria Ángeles Martínez; Joaquim Rovira; Marta Schuhmacher Published in: Environmental Research, Issue 182, 2020, ISSN 0013-9351 Publisher: Academic Press DOI: 10.1016/j.envres.2019.109003 Evaluating the success of Slovenia’s policy on the health of children and adolescents: results of an audit Author(s): Tine Bizjak, Rok Novak, Marko Vudrag, Andreja Kukec, Branko Kontić Published in: International Journal of Public Health, Issue 65/8, 2020, Page(s) 1225-1234, ISSN 1661-8556 Publisher: Birkhauser Verlag DOI: 10.1007/s00038-020-01432-0 Multi-omics analysis reveals that co-exposure to phthalates and metals disturbs urea cycle and choline metabolism Author(s): Nafsika Papaioannou, Emilie Distel, Eliandre de Oliveira, Catherine Gabriel, Ilias S. Frydas, Ourania Anesti, Eleonore A. Attignon, Antonia Odena, Ramon Díaz, Мartine Aggerbeck, Milena Horvat, Robert Barouki, Spyros Karakitsios,Denis A. Sarigiannis Published in: Environmental Research, Issue 192, 2021, ISSN 0013-9351 Publisher: Academic Press DOI: 10.1016/j.envres.2020.110041 Human Biomonitoring Data in Health Risk Assessments Published in Peer-Reviewed Journals between 2016 and 2021: Confronting Reality after a Preliminary Review Author(s): Tine Bizjak; Marco Capodiferro; Deepika Deepika; Öykü Dinçkol; Vazha Dzhedzheia; Lorena Lopez-Suarez; Ioannis Petridis; Agneta A. Runkel; Dayna R. Schultz; Branko Kontić Published in: International Journal of Environmental Research and Public Health, Issue 19, 2022, ISSN 1661-7827 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/ijerph19063362 Assessment of susceptibility to phthalate and DINCH exposure through CYP and UGT single nucleotide polymorphisms Author(s): Anja Stajnko; Agneta Annika Runkel; Tina Kosjek; Janja Snoj Tratnik; Darja Mazej; Ingrid Falnoga; Milena Horvat Published in: Environment International, Issue 159, 2022, ISSN 0160-4120 Publisher: Pergamon Press Ltd. DOI: 10.1016/j.envint.2021.107046 Book chapters (2) Developmental Neurotoxicity of Endocrine Disruptor Chemicals: A Challenge for Behavioral Toxicology Author(s): Gemma Calamandrei, Laura Ricceri Published in: Advances in Neurotoxicology, Issue Chapter 7, Volume 2, 2018, Page(s) 197-225, ISBN 978-0-12-815551-6 Publisher: Elsevier Inc. DOI: 10.1016/bs.ant.2018.03.008 Integrated Translation Framework for Endocrine Disruptors in the Area of Computational Toxicology Author(s): Kumar, V, Deepika Deepika, and R P Sharma Published in: Challenges in Endocrine Disruptor Toxicology and Risk Assessment, Issue Chapter 4, 2021, ISBN 978-1-78801-741-1 Publisher: The Royal Society of Chemistry DOI: 10.1039/9781839160738-00080 Conference proceedings (1) La nostra salut està ancorada en la de la mar Author(s): JOAN O. GRIMALT, MARCO CAPODIFERRO, EVA JUNQUÉ, MERCÈ GARÍ Published in: NATURA, ÚS O ABÚS? (2018-2019), 2020, ISBN 978-84-9965-457-7 Publisher: Institut d’Estudis Catalans DOI: 10.2436/15.0110.22.6 Searching for OpenAIRE data... There was an error trying to search data from OpenAIRE No results available