Deliverables Documents, reports (6) Final dissemination plan Last version of the dissemination plan Health Technology Assessment v2 This second version will encompass how the design of the clinical trial will be in order to gather solid evidence against current gold standard and the assessment related to the performance of the AlleScreening device Health Technology Assessment v1 This is the first version of the Health Technology Assessment. It defines the criteria that a device for detecting allergies in the PoC should meet to be cost-effective against current clinical practice. Handbook on management The Management handbook summarises all the required knowledge for the good management of the project (in terms of administrative forms, financial aspects, quality process…). Initial dissemination plan The dissemination plan encompasses the publications to be developed, the target groups to aim at and the platforms to use to make known the project and its results. Updated dissemination report This is an updated version of the dissemination plan. Other (1) Dissemination material (Project e-newsletters and brochures). Dissemination materials such as newsletters and brochures. Websites, patent fillings, videos etc. (1) Project public website This is a the project website to make known the project. It will also be a tool to manage the internal documents related to the project among its partners. Publications Peer reviewed articles (23) Molecular allergology and its impact in specific allergy diagnosis and therapy Author(s): Domingo Barber, Araceli Diaz‐Perales, Maria M. Escribese, Jörg Kleine‐Tebbe, Paolo M. Matricardi, Markus Ollert, Alexandra F. Santos, Joaquin Sastre Published in: Allergy, 2021, ISSN 0105-4538 Publisher: Blackwell Publishing Inc. DOI: 10.1111/all.14969 New applications of advanced instrumental techniques for the characterization of food allergenic proteins Author(s): Benedé S, Lozano-Ojalvo D, Cristobal S, Costa J, D'Auria E, Velickovic TC, Garrido-Arandia M, Karakaya S, Mafra I, Mazzucchelli G, Picariello G, Romero-Sahagun A, Villa C, Roncada P, Molina E. Published in: Critical Reviews in Food Science and Nutrition, 2021, ISSN 1040-8398 Publisher: Taylor & Francis DOI: 10.1080/10408398.2021.1931806 Real-life evaluation of molecular multiplex IgE test methods in the diagnosis of pollen associated food allergy Author(s): Diem L., Neuherz B., Rohrhofer J., Koidl L., Asero R., Brockow K., Diaz-Perales A., Faber A., Gebhardt J., Torres MJ., Jensen-Jarolim E., Zehetmayer S., Untersmayr E. Published in: Allergy, 2022, ISSN 1398-9995 Publisher: John Wiley and Sons DOI: 10.1111/all.15329 NLRP3 priming due to skin damage precedes LTP allergic sensitization in a mouse model Author(s): Diego Pazos-Castro, Zulema González-Klein, Alma Yuste-Montalvo, Guadalupe Hernández-Ramírez, Alejandro Romero-Sahagún, Vanesa Esteban, María Garrido-Arandia, Jaime Tome-Amat, Araceli Díaz-Perales Published in: Scientific Reports, 2022, ISSN 2045-2322 Publisher: Nature Publishing Group DOI: 10.1038/s41598-022-07421-y The uncertainty and limit of detection in biosensors from immunoassays Author(s): Jesús de Vicente, Álvaro Lavín, Miguel Holgado, María F Laguna, Rafael Casquel, Beatriz Santamaría, Sergio Quintero, Ana L Hernández, Yolanda Ramírez Published in: Measurement Science and Technology, Issue 31/4, 2020, Page(s) 044004, ISSN 0957-0233 Publisher: Institute of Physics and the Physical Society DOI: 10.1088/1361-6501/ab49ec New Label-Free Biosensing for the Evaluation of the AX-024 Inhibitor: Case Study for the Development of New Drugs in Autoimmune Diseases Author(s): Yolanda Ramírez, María Fe Laguna and Miguel Holgado Published in: Sensors, 2022, ISSN 1424-8220 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/s22031218 Are Physicochemical Properties Shaping the Allergenic Potency of Animal Allergens? Author(s): Joana Costa, Caterina Villa, Kitty Verhoeckx, Tanja Cirkovic-Velickovic, Denise Schrama, Paola Roncada, Pedro M. Rodrigues, Cristian Piras, Laura Martín-Pedraza, Linda Monaci, Elena Molina, Gabriel Mazzucchelli, Isabel Mafra, Roberta Lupi, Daniel Lozano-Ojalvo, Colette Larré, Julia Klueber, Eva Gelencser, Cristina Bueno-Diaz, Araceli Diaz-Perales, Sara Benedé, Simona Lucia Bavaro, Annette Kuehn Published in: Clinical Reviews in Allergy & Immunology, 2021, ISSN 1080-0549 Publisher: Humana Press, Inc. DOI: 10.1007/s12016-020-08826-1 Developing an Optical Interferometric Detection Method based biosensor for detecting specific SARS-CoV-2 immunoglobulins in Serum and Saliva, and their corresponding ELISA correlation. Author(s): A.M.M. Murillo; Jaime Tome-Amat; Yolanda Ramírez; María Garrido-Arandia; L.G. Valle; L.G. Valle; Guadalupe Hernandez-Ramirez; L. Tramarin; L. Tramarin; Pedro Herreros; Pedro Herreros; Beatriz Santamaría; Beatriz Santamaría; Araceli Díaz-Perales; Araceli Díaz-Perales; Miguel Holgado; Miguel Holgado Published in: Sensors and Actuators. B, Chemical, Issue 4, 2021, ISSN 0925-4005 Publisher: Elsevier BV DOI: 10.1016/j.snb.2021.130394 ImmunoCAP ISAC in food allergy diagnosis: a systematic review of diagnostic test accuracy Author(s): José-María Maesa, Agnieszka Dobrzynska, Elena Baños-Álvarez, Rebeca Isabel-Gómez, Juan-Antonio Blasco-Amaro Published in: Clinical and experimental allergy, 2021, ISSN 1365-2222 Publisher: John Wiley & Sons Ltd DOI: 10.1111/cea.13871 A new optical interferometric-based in vitro detection system for the specific IgE detection in serum of the main peach allergen Author(s): R.L. Espinosa, M. Garrido-Arandia, A. Romero-Sahagun, P. Herreros, L. Tramarin, M.F. Laguna, A. Díaz-Perales, M. Holgado Published in: Biosensors and Bioelectronics, Issue 169, 2020, Page(s) 112641, ISSN 0956-5663 Publisher: Pergamon Press Ltd. DOI: 10.1016/j.bios.2020.112641 A Comparative Study of Human Saposins Author(s): María Garrido-Arandia, Bruno Cuevas-Zuviría, Araceli Díaz-Perales, Luis Pacios Published in: Molecules, Issue 23/2, 2018, Page(s) 422, ISSN 1420-3049 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/molecules23020422 Energy Landscapes of Ligand Motion Inside the Tunnel-Like Cavity of Lipid Transfer Proteins: The Case of the Pru p 3 Allergen Author(s): Bruno Cuevas-Zuviría, María Garrido-Arandia, Araceli Díaz-Perales, Luis Pacios Published in: International Journal of Molecular Sciences, Issue 20/6, 2019, Page(s) 1432, ISSN 1422-0067 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/ijms20061432 Interaction of Alt a 1 with SLC22A17 in the airway mucosa Author(s): María Garrido‐Arandia, Jaime Tome‐Amat, Diego Pazos‐Castro, Vanesa Esteban, Maria M. Escribese, Guadalupe Hernández‐Ramírez, Alma Yuste‐Montalvo, Domingo Barber, Luis F. Pacios, Araceli Díaz‐Perales Published in: Allergy, 2019, ISSN 0105-4538 Publisher: Blackwell Publishing Inc. DOI: 10.1111/all.13877 Glycosylated nanostructures in sublingual immunotherapy induce long-lasting tolerance in LTP allergy mouse model Author(s): Maria J. Rodriguez, Javier Ramos-Soriano, James R. Perkins, Ainhoa Mascaraque, Maria J. Torres, Francisca Gomez, Araceli Diaz-Perales, Javier Rojo, Cristobalina Mayorga Published in: Scientific Reports, Issue 9/1, 2019, ISSN 2045-2322 Publisher: Nature Publishing Group DOI: 10.1038/s41598-019-40114-7 On the Determination of Uncertainty and Limit of Detection in Label-Free Biosensors Author(s): Álvaro Lavín, Jesús Vicente, Miguel Holgado, María Laguna, Rafael Casquel, Beatriz Santamaría, María Maigler, Ana Hernández, Yolanda Ramírez Published in: Sensors, Issue 18/7, 2018, Page(s) 2038, ISSN 1424-8220 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/s18072038 A Proof-of-Concept of Label-Free Biosensing System for Food Allergy Diagnostics in Biophotonic Sensing Cells: Performance Comparison with ImmunoCAP Author(s): Rocio Espinosa, María Laguna, Fátima Fernández, Beatriz Santamaria, Francisco Sanza, Maria Maigler, Juan Álvarez-Millán, Víctor Canalejas-Tejero, Miguel Holgado Published in: Sensors, Issue 18/8, 2018, Page(s) 2686, ISSN 1424-8220 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/s18082686 A New Device Based on Interferometric Optical Detection Method for Label-Free Screening of C-Reactive Protein Author(s): Maria V. Maigler, Miguel Holgado, Maria Fe Laguna, Francisco J. Sanza, Beatriz Santamaria, Alvaro Lavin, Rocio L. Espinosa Published in: IEEE Transactions on Instrumentation and Measurement, 2018, Page(s) 1-7, ISSN 0018-9456 Publisher: Institute of Electrical and Electronics Engineers DOI: 10.1109/tim.2018.2876073 Performance of basophil activation test and specific IgG4 as diagnostic tools in nonspecific lipid transfer protein allergy: Antwerp‐Barcelona comparison Author(s): Ine I. Decuyper, Mariona Pascal, Athina L. Van Gasse, Christel Mertens, Araceli Díaz‐Perales, Giovanna Araujo, Maria Torradeflot, Josefina Rius, Sara Balsells, Rosa M. Muñoz‐Cano, Joan Bartra, Lynne Li, Vito Sabato, Margo M. Hagendorens, Chris H. Bridts, Luc S. De Clerck, Didier G. Ebo, Margaretha A. Faber Published in: Allergy, Issue 75/3, 2020, Page(s) 616-624, ISSN 0105-4538 Publisher: Blackwell Publishing Inc. DOI: 10.1111/all.14040 A Point-of-Care Based on Label-Free Interferometric Optical Detection Method to Evaluate Interferon Gamma (IFN-γ): A Correlation with the ELISA Technique Author(s): María Fe Laguna Heras, Yolanda Ramirez, Celia Fernández Martín, Rocío L. Espinosa, Alvaro Lavín, Miguel Holgado Published in: Sensors, Issue 20/17, 2020, Page(s) 4776, ISSN 1424-8220 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/s20174776 The diagnosis and management of allergic reactions in patients sensitized to non‐specific lipid transfer proteins Author(s): Isabel J. Skypala, Joan Bartra, Didier G. Ebo, Margaretha Antje Faber, Montserrat Fernández‐Rivas, Francisca Gomez, Olga Luengo, Stephen J. Till, Riccardo Asero, Domingo Barber, Lorenzo Cecchi, Araceli Diaz Perales, Karin Hoffmann‐Sommergruber, Elide Anna Pastorello, Ines Swoboda, Anastasios. P. Konstantinopoulos, Ronald Ree, Enrico Scala Published in: Allergy, 2021, ISSN 0105-4538 Publisher: Blackwell Publishing Inc. DOI: 10.1111/all.14797 Are Physicochemical Properties Shaping the Allergenic Potency of Plant Allergens? Author(s): Joana Costa, Simona Lucia Bavaro, Sara Benedé, Araceli Diaz-Perales, Cristina Bueno-Diaz, Eva Gelencser, Julia Klueber, Colette Larré, Daniel Lozano-Ojalvo, Roberta Lupi, Isabel Mafra, Gabriel Mazzucchelli, Elena Molina, Linda Monaci, Laura Martín-Pedraza, Cristian Piras, Pedro M. Rodrigues, Paola Roncada, Denise Schrama, Tanja Cirkovic-Velickovic, Kitty Verhoeckx, Caterina Villa, Annette Kuehn Published in: Clinical Reviews in Allergy & Immunology, 2021, ISSN 1080-0549 Publisher: Humana Press, Inc. DOI: 10.1007/s12016-020-08810-9 The key to the allergenicity of lipid transfer protein (LTP) ligands: A structural characterization Author(s): Zulema Gonzalez-Klein, Bruno Cuevas-Zuviria, Andrea Wangorsch, Guadalupe Hernandez-Ramirez, Diego Pazos-Castro, Carmen Oeo-Santos, Alejandro Romero-Sahagun, Luis F. Pacios, Jaime Tome-Amat, Stephan Scheurer, Araceli Diaz-Perales, María Garrido-Arandia Published in: Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, Issue 1866/7, 2021, Page(s) 158928, ISSN 1388-1981 Publisher: Elsevier BV DOI: 10.1016/j.bbalip.2021.158928 Optical Vapor Sensors Based on Periodic Resonant Nanopillar Structures Author(s): Sergio Quintero, Rafael Casquel, Maria Fe Laguna, Miguel Holgado Published in: ACS Omega, Issue 5/40, 2020, Page(s) 25913-25918, ISSN 2470-1343 Publisher: ACS Omega DOI: 10.1021/acsomega.0c03279 Intellectual Property Rights Patent (3) OPTICAL METHOD OF DETECTION OF A TARGETED MOLECULE THROUGH AMPLIFICATION IN THE RESPONSE OF INTERFERENCE BY INDEX OF REFRACTION AND DISPERSION (Machine-translation by Google Translate, not legally binding) Application/Publication number: 20 1931066 Date: 2019-12-02 Applicant(s): UNIVERSIDAD POLITECNICA DE MADRID OPTICAL METHOD OF DETECTION OF A TARGETED MOLECULE THROUGH AMPLIFICATION IN THE RESPONSE OF INTERFERENCE BY INDEX OF REFRACTION AND DISPERSION (Machine-translation by Google Translate, not legally binding) Application/Publication number: 20 1931066 Date: 2019-12-02 Applicant(s): BIO OPTICAL DETECTION SL OPTICAL METHOD OF DETECTION OF A TARGETED MOLECULE THROUGH AMPLIFICATION IN THE RESPONSE OF INTERFERENCE BY INDEX OF REFRACTION AND DISPERSION (Machine-translation by Google Translate, not legally binding) Application/Publication number: 20 1931066 Date: 2019-12-02 Searching for OpenAIRE data... 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