CORDIS - Résultats de la recherche de l’UE
CORDIS

CellPrintArray – on-demand nano-scale printing of live cells and compounds for miniaturized cell screening applications

Objectif

The goal of this ERC-PoC project is to develop a prototype system that will enable the addition of libraries of drugs and biochemical molecules, reagents and cells from a 96 source plate directly to individual compartments of the target Droplet Microarray (DMA). The system should have controlled atmosphere (CO2, humidity, temperature) and should allow for dispensing controlled volumes (3-500 nL per experiment) and cell numbers (1-100 per experiment) into individual droplets. We aim to create and evaluate this system for applications commonly performed in pharmaceutical companies and screening centers to enable them to perform miniaturized and more predictive high throughput screenings using physiologically relevant cells such as primary cells, stem cells, biopsy-derived cells and other scarce cell types. The system should allow high-throughput screenings with patient derived cells and therefore will open new possibilities in drug discovery and personalized medicine.

Régime de financement

ERC-POC - Proof of Concept Grant

Institution d’accueil

KARLSRUHER INSTITUT FUER TECHNOLOGIE
Contribution nette de l'UE
€ 150 000,00
Adresse
KAISERSTRASSE 12
76131 Karlsruhe
Allemagne

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Région
Baden-Württemberg Karlsruhe Karlsruhe, Stadtkreis
Type d’activité
Higher or Secondary Education Establishments
Liens
Coût total
€ 150 000,00

Bénéficiaires (1)