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CellPrintArray – on-demand nano-scale printing of live cells and compounds for miniaturized cell screening applications

Cel

The goal of this ERC-PoC project is to develop a prototype system that will enable the addition of libraries of drugs and biochemical molecules, reagents and cells from a 96 source plate directly to individual compartments of the target Droplet Microarray (DMA). The system should have controlled atmosphere (CO2, humidity, temperature) and should allow for dispensing controlled volumes (3-500 nL per experiment) and cell numbers (1-100 per experiment) into individual droplets. We aim to create and evaluate this system for applications commonly performed in pharmaceutical companies and screening centers to enable them to perform miniaturized and more predictive high throughput screenings using physiologically relevant cells such as primary cells, stem cells, biopsy-derived cells and other scarce cell types. The system should allow high-throughput screenings with patient derived cells and therefore will open new possibilities in drug discovery and personalized medicine.

Instytucja przyjmująca

KARLSRUHER INSTITUT FUER TECHNOLOGIE
Wkład UE netto
€ 150 000,00
Adres
Kaiserstrasse 12
76131 Karlsruhe
Niemcy
Rodzaj działalności
Higher or Secondary Education Establishments
Finansowanie spoza UE
€ 0,00

Beneficjenci (1)

KARLSRUHER INSTITUT FUER TECHNOLOGIE
Niemcy
Wkład UE netto
€ 150 000,00
Adres
Kaiserstrasse 12
76131 Karlsruhe
Rodzaj działalności
Higher or Secondary Education Establishments
Finansowanie spoza UE
€ 0,00