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A systems biology approach to investigate cell fate switches in intestinal organoids

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Publications

Retinoic acid signaling drives differentiation toward the absorptive lineage in colorectal cancer

Author(s): Roelof A. Wester, Lisa van Voorthuijsen, Hannah K. Neikes, Jelmer J. Dijkstra, Lieke A. Lamers, Siebren Frölich, Maarten van der Sande, Colin Logie, Rik G.H. Lindeboom, Michiel Vermeulen
Published in: iScience, 24/12, 2021, Page(s) 103444, ISSN 2589-0042
Publisher: Cell Press
DOI: 10.1016/j.isci.2021.103444

RNF 43 truncations trap CK 1 to drive niche‐independent self‐renewal in cancer

Author(s): Maureen Spit, Nicola Fenderico, Ingrid Jordens, Tomasz Radaszkiewicz, Rik GH Lindeboom, Jeroen M Bugter, Alba Cristobal, Lars Ootes, Max van Osch, Eline Janssen, Kim E Boonekamp, Katerina Hanakova, David Potesil, Zbynek Zdrahal, Sylvia F Boj, Jan Paul Medema, Vitezslav Bryja, Bon‐Kyoung Koo, Michiel Vermeulen, Madelon M Maurice
Published in: The EMBO Journal, 39/18, 2020, ISSN 0261-4189
Publisher: Nature Publishing Group
DOI: 10.15252/embj.2019103932

Off-the-shelf proximity biotinylation for interaction proteomics

Author(s): Irene Santos-Barriopedro, Guido van Mierlo, Michiel Vermeulen
Published in: Nature Communications, 12/1, 2021, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-25338-4

Probing the Tumor Suppressor Function of BAP1 in CRISPR-Engineered Human Liver Organoids

Author(s): Benedetta Artegiani, Lisa van Voorthuijsen, Rik G.H. Lindeboom, Daniëlle Seinstra, Inha Heo, Pablo Tapia, Carmen López-Iglesias, Daniel Postrach, Talya Dayton, Rurika Oka, Huili Hu, Ruben van Boxtel, Johan H. van Es, Johan Offerhaus, Peter J. Peters, Jacco van Rheenen, Michiel Vermeulen, Hans Clevers
Published in: Cell Stem Cell, 24/6, 2019, Page(s) 927-943.e6, ISSN 1934-5909
Publisher: Cell Press
DOI: 10.1016/j.stem.2019.04.017

Miniaturised interaction proteomics on a microfluidic platform with ultra-low input requirements

Author(s): Cristina Furlan, René A. M. Dirks, Peter C. Thomas, Robert C. Jones, Jing Wang, Mark Lynch, Hendrik Marks, Michiel Vermeulen
Published in: Nature Communications, 10/1, 2019, Page(s) 1525, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-019-09533-y