Direct cell reprogramming therapy in myocardial regeneration through an engineered multifunctional platform integrating biochemical instructive cues

Design of bioartificial scaffolds as in vitro models of pathological human cardiac tissue

Author(s): Irene Carmagnola, Alice Zoso, Mattia Spedicati, Gerardina Ruocco, Valeria Chiono
Published in: 5th Healthcare & Life Science & Entrepreneurship workshop, 2020, Page(s) 1
Publisher: Vision Dynamics Science & Entrepreneurship

Novel lipoplexes for efficient microRNA delivery to human cardiac fibroblasts

Author(s): Nicoletti, Letizia; Tarricone, Giulia; Paoletti, Camilla; Carla, Divieto; Ilaria, Andreana; Barbara, Stella; Silvia, Arpicco; Mattu, Clara; Chiono, Valeria
Published in: Vancouver Nanomedicine Day, 17 Sept. 2020 - Abstract Booklet, 2020
Publisher: Nanomedicine Innovation Network

In vitro models of human cardiac fibrotic tissue based on bioartificial scaffolds

Author(s): Ireme Carmagnola; Alice ZOSO; Valeria Chiono
Published in: Linz 2019 22nd European Congress on Alternatives to Animal Testing - Eusaat 2019 - 19th Annual Congress of EUSAAT - ALTEX PROCEEDINGS, 2019
Publisher: Springer Spektrum

MICRORNA-RELEASING LIPOPLEXES FOR DIRECT CARDIAC REPROGRAMMING IN PATHOLOGICAL CARDIAC TISSUE

Author(s): Letizia Nicoletti; CAMILLA PAOLETTI; Tarricone, Giulia; Carla, Divieto; Ilaria, Andreana; Barbara, Stella; Silvia, Arpicco; Clara Mattu; Valeria Chiono
Published in: "Abstract of the conference ""Nature Conferences - RNA at the Bench and Bedside II"", 11-13 November 2020", 2020
Publisher: Politecnico di Torino - IRIS

Tissue-engineered models of human pathological cardiac tissue through bioartificial scaffolds

Author(s): Ireme Carmagnola; Alice ZOSO; Spedicati, Mattia; Ruocco, Gerardina; Valeria Chiono
Published in: "Abstract of the ""11TH World Biomaterials Congress"", online, 11 - 15 Dec. 2020", 2020
Publisher: Politecnico di Torino - IRIS

“Bioartificial” scaffolds for the development of in vitro models of human cardiac fibrotic tissue

Author(s): Ireme Carmagnola; Alice ZOSO; Valeria Chiono
Published in: Abstract of the 30th Annual Conference of the European Society for Biomaterials (ESB), Dresden (Germany), Sept. 9-13, 2019; Dresden (DE)., 2019
Publisher: PORTO-IRIS

Direct reprogramming of human cardiac fibroblasts into cardiomyocytes in 2D and 3D culture microenvironments

Author(s): Paoletti Camilla, Divieto Carla, Chiono, Valeria
Published in: Joint Meeting of the ESC Working Groups on Myocardial Function and Cellular Biology of the Heart, 9-11 May 2019, Naples (Italy), 2019
Publisher: PORTO-Iris

Biomimetic scaffolds and multifunctional materials in the regeneration of pathological cardiac tissue

Author(s): Irene Carmagnola, Alice Zoso, Camilla Paoletti, Giulia Tarricone, Mattia Spedicati, Gerardina Ruocco, Franca di Meglio, Daria Nurzynska, Carla Divieto, Valeria Chiono
Published in: Abstract of NICE – 2020 International Conference, 2020
Publisher: NICE – 2020 International Conference

MicroRNA releasing lipoplexes as potential nanosystems against COVID 19

Author(s): Letizia Nicoletti; CAMILLA PAOLETTI; Tarricone, Giulia; Carla, Divieto; Ilaria, Andreana; Barbara, Stella; Silvia, Arpicco; Clara Mattu; Valeria Chiono
Published in: Virtual FISV Symposium on SARS CoV 2 Biology and COVID 19: Current research and perspectives Programme and Abstracts September 16, 2020, 2020
Publisher: Federazione Italiana Scienze della Vita

Direct reprogramming of human cardiac fibroblasts towards the cardiac phenotype through non-viral approaches.

Author(s): Camilla Paoletti, Letizia Nicoletti, Giulia Tarricone, Carla Divieto3 Franca Di Meglio, Daria Nurzynska, Clara Mattu, Ilaria Andreana, Silvia Arpicco, Barbara Stella, Valeria Chiono
Published in: 5th Healthcare & Life Science & Entrepreneurship workshop, 2020, Page(s) 1
Publisher: Vision Dynamics Science and Entrepreneurship

Direct reprogramming of human fibroblasts as a novel tool in cardiac tissue engineering

Author(s): Valeria Chiono
Published in: TERMIS EU2019 Conference Book, 2019, Page(s) 813
Publisher: Termis

Direct reprogramming of human cardiac fibroblasts to cardiomyocytes using microRNA mimics

Author(s): Camilla Paoletti, Carla Divieto, Franca Di Meglio, Daria Nurzynska, Valeria Chiono
Published in: Termis EU 2019 Conference Book, 2019, Page(s) 1442
Publisher: Termis

Direct cell reprogramming as a new emerging strategy in cardiac regeneration

Author(s): Chiono, Valeria; Paoletti, Camilla; Carla, Divieto; Franca Di Meglio,; Clotilde, Castaldo; Daria, Nurzynska
Published in: Termis WC 2018 programme, 2018, Page(s) 14
Publisher: Termis

Lipoplexes for miRNA delivery in myocardial regeneration

Author(s): Nicoletti, Letizia; Tarricone, Giulia; Paoletti, Camilla; Carla, Divieto; Ilaria, Andreana; Barbara, Stella; Silvia, Arpicco; Mattu, Clara; Chiono, Valeria
Published in: Nano Day IV Program and Book of Abstracts (Nano Day IV; Milan, 11-14 Dec. 2020), 2019, Page(s) 136
Publisher: University of Parma and Cinsa

In vitro models of human cardiac fibrotic tissue based on bioartificial scaffolds

Author(s): Carmagnola, Irene; Zoso, Alice; Chiono, Valeria
Published in: ALTEX Proceeding, 2019, Page(s) 29, ISSN 2194-0479
Publisher: Spinger Spektrum

Thermosensitive bioartificial hydrogels as smart injectable and biocompatible systems allowing post-injection chemical crosslinking

Author(s): Chiono, Valeria; Laurano, Rossella; Zoso, Alice; Boffito, Monica
Published in: European Society for Biomaterials (ESB) programme, 2019, Page(s) "#943"
Publisher: ESB

Direct reprogramming of human cardiac fibroblasts to cardiomyocytes using microRNA mimics

Author(s): Camilla, Paoletti, Carla Divieto, Franca Di Meglio, Daria Nurzynska, Valeria Chiono
Published in: JRC Summer School 2019: Non-Animal Aprroaches in Science. Challenges & Future Directions; 21-24 May 2019, Ispra (IT), 2019, Page(s) 74
Publisher: JRC

INFLUENCE OF 3D CULTURE MICROENVIRONMENT ON MICRORNA-MEDIATED DIRECT REPROGRAMMING OF HUMAN CARDIAC FIBROBLASTS INTO CARDIOMYOCYTES

Author(s): Camilla Paoletti, Carla Divieto, Franca Di Meglio, Daria Nurzynska, Valeria Chiono
Published in: Advanced Cell Therapies and Tissue Engineering, 2019, Page(s) 32
Publisher: Ospedale San Raffaele and Nature

IN VITRO MODELS OF HUMAN PATHOLOGICAL CARDIAC TISSUE VIA BIOARTIFICIAL SCAFFOLDS

Author(s): Valeria Chiono, Alice Zoso, Mattia Spedicati, Gerardina Ruocco, Irene Carmagnola
Published in: Advanced Cell Therapies and Tissue Engineering, 2019, Page(s) 28
Publisher: Ospedale San Raffaele and Nature

In vitro models of fibrotic cardiac tissue as a potential tool for testing cardioprotective therapies for cardiovascular diseases related to COVID-19

Author(s): Mattia Spedicati, Gerardina Ruocco, Alice Zoso, Irene Carmagnola, Valeria Chiono
Published in: Virtual FISV Symposium on SARS-CoV-2 Biology and COVID-19: Current research and perspectives, 2020, ISBN 978-88-943891-2-8
Publisher: FISV - Federazione Italiana Scienze della Vita

Using Poloxamer® 407 as Building Block of Amphiphilic Poly(ether urethane)s: Effect of its Molecular Weight Distribution on Thermo-Sensitive Hydrogel Performances in the Perspective of Their Biomedical Application

Author(s): Rossella Laurano, Michela Abrami, Mario Grassi, Gianluca Ciardelli, Monica Boffito, Valeria Chiono
Published in: Frontiers in Materials, Issue 7, 2020, ISSN 2296-8016
Publisher: Frontiers
DOI: 10.3389/fmats.2020.594515

Human Cardiac Progenitor Cell-Derived Extracellular Vesicles Exhibit Promising Potential for Supporting Cardiac Repair in Vitro

Author(s): Veronica Romano; Immacolata Belviso; Anna Maria Sacco; Domenico Cozzolino; Daria Nurzynska; Cristiano Amarelli; Ciro Maiello; Felice Sirico; Franca Di Meglio; Clotilde Castaldo
Published in: Front Physiol, 2022, ISSN 1664-042X
Publisher: Frontiers Research Foundation
DOI: 10.3389/fphys.2022.879046

The Broad Spectrum of LMNA Cardiac Diseases: From Molecular Mechanisms to Clinical Phenotype

Author(s): Silvia Crasto, Ilaria My, Elisa Di Pasquale
Published in: Frontiers in Physiology, Issue 11, 2020, ISSN 1664-042X
Publisher: Frontiers Research Foundation
DOI: 10.3389/fphys.2020.00761

MicroRNA-Mediated Direct Reprogramming of Human Adult Fibroblasts Toward Cardiac Phenotype

Author(s): C. Paoletti, C. Divieto, G. Tarricone, F. Di Meglio, D. Nurzynska, V. Chiono
Published in: Frontiers in Bioengineering and Biotechnology, Issue 8, 2020, ISSN 2296-4185
Publisher: Frontiers
DOI: 10.3389/fbioe.2020.00529

In Vitro Mechanical Stimulation to Reproduce the Pathological Hallmarks of Human Cardiac Fibrosis on a Beating Chip and Predict The Efficacy of Drugs and Advanced Therapies

Author(s): Roberta Visone; Camilla Paoletti; Alessandro Cordiale; Letizia Nicoletti; Carla Divieto; Marco Rasponi; Valeria Chiono; Paola Occhetta
Published in: Adv Healthc Mater, 2024, ISSN 2192-2659
Publisher: World Scientific
DOI: 10.1002/adhm.202301481

Editorial: Advanced Therapies for Cardiac Regeneration

Author(s): Monica Boffito, Susanna Sartori, Ipsita Roy, Irene Carmagnola, Valeria Chiono
Published in: Frontiers in Bioengineering and Biotechnology, 2021, ISSN 2296-4185
Publisher: Frontiers
DOI: 10.3389/fbioe.2021.644076

Design of Injectable Bioartificial Hydrogels by Green Chemistry for Mini-Invasive Applications in the Biomedical or Aesthetic Medicine Fields

Author(s): Rossella Laurano; Monica Boffito; Claudio Cassino; Francesco Liberti; Gianluca Ciardelli; Valeria Chiono
Published in: Gels; Volume 9; Issue 1; Pages: 59, 2023, ISSN 2310-2861
Publisher: MDPI
DOI: 10.3390/gels9010059

Cardiac Tissue-like 3D Microenvironment Enhances Route towards Human Fibroblast Direct Reprogramming into Induced Cardiomyocytes by microRNAs

Author(s): Camilla Paoletti; Elena Marcello; Maria Luna Melis; Carla Divieto; Daria Nurzynska; Valeria Chiono
Published in: Cells; Volume 11; Issue 5; Pages: 800, Issue 17, 2022, ISSN 2073-4409
Publisher: MDPI
DOI: 10.3390/cells11050800

Lipoplexes for effective in vitro delivery of microRNAs to adult human cardiac fibroblasts for perspective direct cardiac cell reprogramming

Author(s): Letizia Nicoletti; Camilla Paoletti; Giulia Tarricone; Ilaria Andreana; Barbara Stella; Silvia Arpicco; Carla Divieto; Clara Mattu; Valeria Chiono
Published in: Nanomedicine . 2022 Sep;45:102589. doi: 10.1016/j.nano.2022.102589. Epub 2022 Jul 28, Issue 20, 2022, ISSN 1549-9634
Publisher: Elsevier BV
DOI: 10.1016/j.nano.2022.102589

Zein as a renewable material for the preparation of green nanoparticles for drug delivery

Author(s): Tivano, Francesca; Chiono, Valeria
Published in: Frontiers in Biomaterials Science, 2023, ISSN 2813-3749
Publisher: Frontiers
DOI: 10.3389/fbiom.2023.1156403

Impact of Biomaterials on Differentiation and Reprogramming Approaches for the Generation of Functional Cardiomyocytes

Author(s): Camilla Paoletti, Carla Divieto, Valeria Chiono
Published in: Cells, Issue 7/9, 2018, Page(s) 114, ISSN 2073-4409
Publisher: MDPI
DOI: 10.3390/cells7090114

MicroRNA delivery through nanoparticles

Author(s): Sharon Wei Ling Lee, Camilla Paoletti, Marco Campisi, Tatsuya Osaki, Giulia Adriani, Roger D. Kamm, Clara Mattu, Valeria Chiono
Published in: Journal of Controlled Release, Issue 313, 2019, Page(s) 80-95, ISSN 0168-3659
Publisher: Elsevier BV
DOI: 10.1016/j.jconrel.2019.10.007

In vitro models of human cardiac fibrotic tissue on ‘bioartificial’ scaffolds

Author(s): Alice Zoso, Irene Carmagnola, Gerardina Ruocco, Mattia Spedicati, Valeria Chiono
Published in: Biomedical Science and Engineering, 2020, Page(s) 1, ISSN 2531-9892
Publisher: Page Press
DOI: 10.4081/bse.2019.122

iPS, organoids and 3D models as advanced tools for in vitro toxicology

Author(s): Nathalie Steimberg
Published in: ALTEX, 2020, Page(s) 136-140, ISSN 1868-596X
Publisher: Springer Spektrum | Springer-Verlag GmbH
DOI: 10.14573/altex.1911071

Toward Cardiac Regeneration: Combination of Pluripotent Stem Cell-Based Therapies and Bioengineering Strategies

Author(s): Marta Mazzola, Elisa Di Pasquale
Published in: Frontiers in Bioengineering and Biotechnology, Issue 8, 2020, Page(s) 23, ISSN 2296-4185
Publisher: Frontiers
DOI: 10.3389/fbioe.2020.00455

Biomimetic design of bioartificial scaffolds for the in vitro modelling of human cardiac fibrosis

Author(s): Mattia Spedicati, Gerardina Ruocco, Alice Zoso, Leonardo Mortati, Andrea Lapini, Andrea Delledonne, Carla Divieto, Veronica Romano, Clotilde Castaldo, Franca Di Meglio, Daria Nurzynska, Irene Carmagnola, Valeria Chiono
Published in: Front. Bioeng. Biotechnol., 2022, ISSN 2296-4185
Publisher: Frontiers
DOI: 10.3389/fbioe.2022.983872

Biomaterials-Enhanced Intranasal Delivery of Drugs as a Direct Route for Brain Targeting

Author(s): Elena Marcello; Valeria Chiono
Published in: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24043390

Electroconductive Photo-Curable PEGDA-Gelatin/PEDOT:PSS Hydrogels for Prospective Cardiac Tissue Engineering Application

Author(s): Daniele Testore, Alice Zoso, Galder Kortaberria, Marco Sangermano, Valeria Chiono
Published in: Front. Bioeng. Biotechnol., 24 June 2022 Sec. Biomaterials, Volume 10 - 2022, Issue 10, 2022, ISSN 2296-4185
Publisher: Frontiers
DOI: 10.3389/fbioe.2022.897575

Biomimetic Electrospun Scaffold-Based In Vitro Model Resembling the Hallmarks of Human Myocardial Fibrotic Tissue

Author(s): Gerardina Ruocco; Alice Zoso; Leonardo Mortati; Irene Carmagnola; Valeria Chiono
Published in: ACS Biomater. Sci. Eng., 2023, ISSN 2373-9878
Publisher: ACS
DOI: 10.1021/acsbiomaterials.3c00483

Bioengineering Methods in MicroRNA-Mediated Direct Reprogramming of Fibroblasts Into Cardiomyocytes.

Author(s): Camilla Paoletti; Valeria Chiono
Published in: Frontiers in Cardiovascular Medicine, Issue 9, 2021, ISSN 2297-055X
Publisher: Frontiers
DOI: 10.3389/fcvm.2021.750438

Modeling Nanocarrier Transport across a 3D In Vitro Human Blood‐Brain–Barrier Microvasculature

Author(s): Sharon Wei Ling Lee, Marco Campisi, Tatsuya Osaki, Luca Possenti, Clara Mattu, Giulia Adriani, Roger Dale Kamm, Valeria Chiono
Published in: Advanced Healthcare Materials, Issue 9/7, 2020, Page(s) 1901486, ISSN 2192-2640
Publisher: John Wiley and Sons Ltd
DOI: 10.1002/adhm.201901486

Direct Reprogramming of Adult Human Cardiac Fibroblasts into Induced Cardiomyocytes Using miRcombo

Author(s): Camilla Paoletti, Carla Divieto, Valeria Chiono
Published in: Cardiac Gene Therapy. Methods in Molecular Biology, Issue 2573, 2022, ISBN 978-1-0716-2706-8
Publisher: Springer Protocols
DOI: 10.1007/978-1-0716-2707-5_3

Cell–biomaterial interactions: the role of ligand functionalization

Author(s): Alice Zoso, Monica Boffito, Rossella Laurano, Irene Carmagnola, Valeria Chiono
Published in: Handbook of Biomaterials Biocompatibility, 2020, Page(s) 139-173, ISBN 9780081029671
Publisher: Woodhead Publishing Series in Biomaterials - Elsevier
DOI: 10.1016/b978-0-08-102967-1.00009-8

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