Dare to Approach: A Neurocognitive Approach to Alleviating Persistent Avoidance in Anxiety Disorders

Información del proyecto

DARE2APPROACH

Identificador del acuerdo de subvención: 772337

DOI

10.3030/772337

Proyecto cerrado

Fecha de la firma de la CE 3 Mayo 2018

Fecha de inicio 1 Enero 2019

Fecha de finalización 30 Noviembre 2024

Financiado con arreglo a

• EXCELLENT SCIENCE - European Research Council (ERC)

Coste total

€ 2 000 000,00

Aportación de la UE

€ 2 000 000,00

Coordinado por

STICHTING RADBOUD UNIVERSITEIT
Netherlands

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Open Research Data Pilot (1)

Data Management Plan

The Data Management Plan describes the data management life cycle for all data sets that will be collected, processed or generated by the action. It is a document describing what data will be collected, processed or generated and following what methodology and standards, whether and how this data will be shared and/or made open, and how it will be curated and preserved.

Publicaciones

Peer reviewed articles (36)

Frontal Control Over Automatic Emotional Action Tendencies Predicts Acute Stress Responsivity

Autores: Reinoud Kaldewaij, Saskia B.J. Koch, Wei Zhang, Mahur M. Hashemi, Floris Klumpers, Karin Roelofs
Publicado en: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, Edición 4/11, 2019, Página(s) 975-983, ISSN 2451-9022
Editor: Elsevier
DOI: 10.1016/j.bpsc.2019.06.011

Acute-stress induced change in salience network coupling prospectively predicts post-trauma symptom-development

Autores: Wei Zhang, Reinoud Kaldewaij, Mahur M. Hashemi, Saskia B.J. Koch, Annika Smit, Vanessa van Ast, Christian F. Beckmann, Floris Klumpers, Karin Roelofs
Publicado en: Translational Psychiatry, Edición 12, 2022, Página(s) 63, ISSN 2158-3188
Editor: Nature Publishing Group
DOI: 10.1101/2021.07.03.21259969

The neurocomputational link between defensive cardiac states and approach-avoidance arbitration under threat

Autores: Felix H. Klaassen, Lycia D. de Voogd, Anneloes M. Hulsman, Jill X. O’Reilly, Floris Klumpers, Bernd Figner, Karin Roelofs
Publicado en: Communications Biology, Edición 7, 2023, Página(s) 576, ISSN 2399-3642
Editor: Nature Portfolio
DOI: 10.1101/2023.11.10.566569

Volume of subcortical brain regions in social anxiety disorder: mega-analytic results from 37 samples in the ENIGMA-Anxiety Working Group

Autores: Nynke A. Groenewold, Janna Marie Bas-Hoogendam, Alyssa R. Amod, Max A. Laansma, Laura S. Van Velzen, Moji Aghajani, Kevin Hilbert, Hyuntaek Oh, Ramiro Salas, Andrea P. Jackowski, Pedro M. Pan, Giovanni A. Salum, James R. Blair, Karina S. Blair, Joy Hirsch, Spiro P. Pantazatos, Franklin R. Schneier, Ardesheer Talati, Karin Roelofs, Inge Volman, Laura Blanco-Hinojo, Narcís Cardoner, Jesus Pujol, Ka
Publicado en: Molecular Psychiatry, Edición 28, 2023, Página(s) 1079-1089, ISSN 1359-4184
Editor: Nature Publishing Group
DOI: 10.1038/s41380-022-01933-9

Individual differences in costly fearful avoidance and the relation to psychophysiology

Autores: Anneloes M. Hulsman, Reinoud Kaldewaij, Mahur M. Hashemi, Wei Zhang, Saskia B.J. Koch, Bernd Figner, Karin Roelofs, Floris Klumpers
Publicado en: Behaviour Research and Therapy, Edición 137, 2021, Página(s) 103788, ISSN 0005-7967
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.brat.2020.103788

Behavioral inhibition, negative parenting, and social withdrawal: Longitudinal associations with loneliness during early, middle, and late adolescence

Autores: Maaike Verhagen, Mare Derks, Karin Roelofs, Dominique Maciejewski
Publicado en: Child Development, Edición 94, 2023, Página(s) 512-528, ISSN 0009-3920
Editor: Blackwell Publishing Inc.
DOI: 10.1111/cdev.13874

Improving emotional-action control by targeting long-range phase-amplitude neuronal coupling

Autores: Bob Bramson, Hanneke EM den Ouden, Ivan Toni, Karin Roelofs
Publicado en: eLife, Edición 9, 2020, ISSN 2050-084X
Editor: eLife Sciences Publications
DOI: 10.7554/elife.59600

Human defensive freezing: Associations with hair cortisol and trait anxiety

Autores: Mahur M. Hashemi, Wei Zhang, Reinoud Kaldewaij, Saskia B.J. Koch, Annika Smit, Bernd Figner, Rosa Jonker, Floris Klumpers, Karin Roelofs
Publicado en: Psychoneuroendocrinology, Edición 133, 2021, Página(s) 105417, ISSN 0306-4530
Editor: Pergamon Press
DOI: 10.1016/j.psyneuen.2021.105417

Human Lateral Frontal Pole Contributes to Control over Emotional Approach–Avoidance Actions

Autores: Bob Bramson, Davide Folloni, Lennart Verhagen, Bart Hartogsveld, Rogier B. Mars, Ivan Toni, Karin Roelofs
Publicado en: The Journal of Neuroscience, Edición 40/14, 2020, Página(s) 2925-2934, ISSN 0270-6474
Editor: Society for Neuroscience
DOI: 10.1523/jneurosci.2048-19.2020

The enhancing effects of testosterone in exposure treatment for social anxiety disorder: a randomized proof-of-concept trial

Autores: Moniek H. M. Hutschemaekers, Rianne A. de Kleine, Gert-Jan Hendriks, Mirjam Kampman, Karin Roelofs
Publicado en: Translational Psychiatry, Edición 11/1, 2021, ISSN 2158-3188
Editor: Nature Publishing Group
DOI: 10.1038/s41398-021-01556-8

Emerging Adults’ Mental Health During the COVID-19 Pandemic: A Prospective Longitudinal Study on the Importance of Social Support

Autores: Yvonne H. M. van den Berg, William J. Burk, Antonius H. N. Cillessen, Karin Roelofs
Publicado en: Emerging Adulthood, Edición 9, 2021, Página(s) 618-630, ISSN 2167-6968
Editor: SAGE Publications Ltd
DOI: 10.1177/21676968211039979

A neurocognitive theory of flexible emotion control: The role of the lateral frontal pole in emotion regulation

Autores: Karin Roelofs, Bob Bramson, Ivan Toni
Publicado en: Annals of the New York Academy of Sciences, Edición 1525, 2023, Página(s) 28-40, ISSN 0077-8923
Editor: New York Academy of Sciences
DOI: 10.1111/nyas.15003

Trauma-induced human glucocorticoid receptor expression increases predict subsequent HPA-axis blunting in a prospective longitudinal design

Autores: Lycia D. de Voogd, Rosalie Anne Kampen, Reinoud Kaldewaij, Wei Zhang, Mahur Melina Hashemi, Saskia B.J. Koch, Floris Klumpers, Jeffrey C. Glennon, Karin Roelofs
Publicado en: Psychoneuroendocrinology, Edición 146, 2023, Página(s) 105909, ISSN 0306-4530
Editor: Pergamon Press
DOI: 10.1016/j.psyneuen.2022.105909

Freezing revisited: coordinated autonomic and central optimization of threat coping

Autores: Karin Roelofs, Peter Dayan
Publicado en: Nature Reviews Neuroscience, Edición 23, 2023, Página(s) 568-580, ISSN 1471-003X
Editor: Nature Publishing Group
DOI: 10.1038/s41583-022-00608-2

No evidence for disruption of reconsolidation of conditioned threat memories with a cognitively demanding intervention

Autores: Lars Jaswetz, Lycia D. de Voogd, Eni S. Becker, Karin Roelofs
Publicado en: Scientific Reports, Edición 12, 2022, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-022-10184-1

Reply to ‘Post-encounter freezing during approach–avoidance conflict: the role of the hippocampus’

Autores: Karin Roelofs, Felix H. Klaassen, Peter Dayan
Publicado en: Nature Reviews Neuroscience, Edición 24, 2023, Página(s) 453-454, ISSN 1471-003X
Editor: Nature Publishing Group
DOI: 10.1038/s41583-023-00704-x

Anxious individuals shift emotion control from lateral frontal pole to dorsolateral prefrontal cortex

Autores: Bob Bramson, Sjoerd Meijer, Annelies van Nuland, Ivan Toni, Karin Roelofs
Publicado en: Nature Communications, Edición 14, 2023, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-023-40666-3

The gene environment aetiology of freezing and its relationship with internalizing symptoms during adolescence

Autores: Leslie K. Held, Jacqueline M. Vink, Frank Vitaro, Mara Brendgen, Ginette Dionne, Lysandre Provost, Michel Boivin, Isabelle Ouellet-Morin, Karin Roelofs
Publicado en: eBioMedicine, Edición 81, 2022, Página(s) 104094, ISSN 2352-3964
Editor: Elsevier BV
DOI: 10.1016/j.ebiom.2022.104094

Social avoidance and testosterone enhanced exposure efficacy in women with social anxiety disorder: A pilot investigation

Autores: Moniek H.M. Hutschemaekers, Rianne A. de Kleine, Mirjam Kampman, Jasper A.J. Smits, Karin Roelofs
Publicado en: Psychoneuroendocrinology, Edición 158, 2023, Página(s) 106372, ISSN 0306-4530
Editor: Pergamon Press
DOI: 10.1016/j.psyneuen.2023.106372

Context and trade-offs characterize real-world threat detection systems: A review and comprehensive framework to improve research practice and resolve the translational crisis

Autores: Markus Fendt, Michael H. Parsons, Raimund Apfelbach, Alexandra J.R. Carthey, Chris R. Dickman, Thomas Endres, Anke S.K. Frank, Daniel E. Heinz, Menna E. Jones, Yasushi Kiyokawa, Judith C. Kreutzmann, Karin Roelofs, Miriam Schneider, Julia Sulger, Carsten T. Wotjak, Daniel T. Blumstein
Publicado en: Neuroscience & Biobehavioral Reviews, Edición 115, 2020, Página(s) 25-33, ISSN 0149-7634
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.neubiorev.2020.05.002

Emotion regulation from an action-control perspective

Autores: Bob Bramson, Ivan Toni, Karin Roelofs
Publicado en: Neuroscience & Biobehavioral Reviews, 2023, ISSN 1873-7528
Editor: Elsevier
DOI: 10.31234/osf.io/tr5um

Approach-Avoidance Decisions Under Threat: The Role of Autonomic Psychophysiological States

Autores: James J. A. Livermore, Felix H. Klaassen, Bob Bramson, Anneloes M. Hulsman, Sjoerd W. Meijer, Leslie Held, Floris Klumpers, Lycia D. de Voogd, Karin Roelofs
Publicado en: Frontiers in Neuroscience, Edición 15, 2021, ISSN 1662-453X
Editor: Frontiers Media SA
DOI: 10.3389/fnins.2021.621517

Defensive freezing and its relation to approach–avoidance decision-making under threat

Autores: Felix H. Klaassen, Leslie Held, Bernd Figner, Jill X. O’Reilly, Floris Klumpers, Lycia D. de Voogd, Karin Roelofs
Publicado en: Scientific Reports, Edición 11/1, 2021, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-021-90968-z

The functional role of cardiac activity in perception and action

Autores: L.I. Skora, J.J.A. Livermore, K. Roelofs
Publicado en: Neuroscience & Biobehavioral Reviews, Edición 137, 2023, Página(s) 104655, ISSN 0149-7634
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.neubiorev.2022.104655

Age differences in intertemporal choice among children, adolescents, and adults

Autores: Iris Ikink, Anna C.K. van Duijvenvoorde, Hilde Huizenga, Karin Roelofs, Bernd Figner
Publicado en: Journal of Experimental Child Psychology, Edición 233, 2024, Página(s) 105691, ISSN 0022-0965
Editor: Academic Press
DOI: 10.1016/j.jecp.2023.105691

Postural freezing relates to startle potentiation in a human fear‐conditioning paradigm

Autores: Vanessa A. van Ast, Floris Klumpers, Raoul P. P. P. Grasman, Angelos‐Miltiadis Krypotos, Karin Roelofs
Publicado en: Psychophysiology, Edición 59, 2023, ISSN 0048-5772
Editor: Blackwell Publishing Inc.
DOI: 10.1111/psyp.13983

Behavioral inhibition as an early life predictor of callous-unemotional traits

Autores: Anna L. Dapprich, Anna Tyborowska, Hannah C. M. Niermann, Eni S. Becker, Antonius H. N. Cillessen, Karin Roelofs
Publicado en: International Journal of Behavioral Development, Edición 46, 2023, Página(s) 333-345, ISSN 0165-0254
Editor: SAGE Publications
DOI: 10.1177/01650254221100245

Discriminating stress from rest based on resting‐state connectivity of the human brain: A supervised machine learning study

Autores: Wei Zhang, Alberto Llera, Mahur M. Hashemi, Reinoud Kaldewaij, Saskia B. J. Koch, Christian F. Beckmann, Floris Klumpers, Karin Roelofs
Publicado en: Human Brain Mapping, Edición 41/11, 2020, Página(s) 3089-3099, ISSN 1065-9471
Editor: John Wiley & Sons Inc.
DOI: 10.1002/hbm.25000

Endogenous testosterone levels are predictive of symptom reduction with exposure therapy in social anxiety disorder

Autores: M.H.M. Hutschemaekers, R.A. de Kleine, M.L. Davis, M. Kampman, J.A.J. Smits, K. Roelofs
Publicado en: Psychoneuroendocrinology, Edición 115, 2020, Página(s) 104612, ISSN 0306-4530
Editor: Pergamon Press
DOI: 10.1016/j.psyneuen.2020.104612

Patients with Ventromedial Prefrontal Lesions Show an Implicit Approach Bias to Angry Faces

Autores: Macià Buades-Rotger, Anne-Kristin Solbakk, Matthias Liebrand, Tor Endestad, Ingrid Funderud, Paul Siegwardt, Dorien Enter, Karin Roelofs, Ulrike M. Krämer
Publicado en: Journal of Cognitive Neuroscience, Edición 33, 2021, Página(s) 1069-1081, ISSN 0898-929X
Editor: Cambridge Center for Behavioral Studies
DOI: 10.1162/jocn_a_01706

Pavlovian-to-instrumental transfer in intertemporal choice

Autores: Floor Burghoorn, Vivian R. Heuvelmans, Anouk Scheres, Karin Roelofs, Bernd Figner
Publicado en: Judgment and Decision Making, Edición 19, 2024, Página(s) 1–34, ISSN 1930-2975
Editor: Society for Judgment and Decision Making
DOI: 10.1017/jdm.2023.42

The association between serotonin transporter availability and the neural correlates of fear bradycardia

Autores: Pieter Schipper, Marlies Hiemstra, Kari Bosch, Desiree Nieuwenhuis, Annalisa Adinolfi, Sabine Glotzbach, Bart Borghans, Dora Lopresto, Guillén Fernández, Floris Klumpers, Erno J. Hermans, Karin Roelofs, Marloes J. A. G. Henckens, Judith R. Homberg
Publicado en: Proceedings of the National Academy of Sciences, Edición 116/51, 2019, Página(s) 25941-25947, ISSN 0027-8424
Editor: National Academy of Sciences
DOI: 10.1073/pnas.1904843116

Structural Brain Correlates of Childhood Inhibited Temperament: An ENIGMA-Anxiety Mega-analysis

Autores: Janna Marie Bas-Hoogendam, Rachel Bernstein, Brenda E. Benson, Kristin A. Buss, Kelley E. Gunther, Koraly Pérez-Edgar, Giovanni A. Salum, Andrea P. Jackowski, Rodrigo A. Bressan, André Zugman, Kathryn A. Degnan, Courtney A. Filippi, Nathan A. Fox, Heather A. Henderson, Alva Tang, Selin Zeytinoglu, Anita Harrewijn, Manon H.J. Hillegers, Tonya White, Marinus H. van IJzendoorn, Carl E. Schwartz, Ju
Publicado en: Journal of the American Academy of Child & Adolescent Psychiatry, Edición 61, 2022, Página(s) 1182-1188, ISSN 0890-8567
Editor: Elsevier BV
DOI: 10.1016/j.jaac.2022.04.023

Perceptual control or action-selection? Comment on: a perceptual control theory of emotional action

Autores: Bob Bramson, Karin Roelofs
Publicado en: Cognition and Emotion, Edición 37, 2023, Página(s) 1193-1198, ISSN 0269-9931
Editor: Psychology Press
DOI: 10.1080/02699931.2023.2269830

Acute threat enhances perceptual sensitivity without affecting the decision criterion

Autores: Lycia D. de Voogd, Eline Hagenberg, Ying Joey Zhou, Floris P. de Lange, Karin Roelofs
Publicado en: Scientific Reports, Edición 12, 2022, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-022-11664-0

Neural patterns of threat response in adolescents predict vulnerability for and resilience against internalizing symptoms during COVID-19 waves

Autores: Anna Tyborowska, Yvonne van den Berg, Mahur M. Hashemi, Hannah C.M. Niermann, Antonius H.N. Cillessen, Ivan Toni, Karin Roelofs
Publicado en: Neuroimage: Reports, Edición 3, 2023, Página(s) 100177, ISSN 2666-9560
Editor: Elsevier
DOI: 10.1016/j.ynirp.2023.100177

Thesis and dissertations (1)

Rhythmic control: Prefrontal cortical mechanisms of emotional-action control

Autores: Bramson, B.P.
Publicado en: Rhythmic control: Prefrontal cortical mechanisms of emotional-action control, Edición 3, 2021, Página(s) 1-169, ISBN 9789464162233
Editor: S.l. : s.n.