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Nanostructural surface development for dental implant manufacturing

Deliverables

Stability, biocompatibility and resistivity to aggressive environment of the developed dental implants with modified surface

Stability biocompatibility and resistivity to aggressive environment of the developed dental implants with modified surface will be evaluated

Recommendation for in-vivo application of implants with different surface treatment

Recommendation for invivo application of implants with different surface treatment will be prepared

Recommendation for development of dental implants with optimal mechanical properties

Validation and optimization of parameters will be performed

Trained 35 ESR, 37 ER and 17 management staff members

35 ESR 37 ER and 17 management staff members will be trained

Methodology of ZrTiNb-based metal alloy preparation

Methodology of ZrTiNb-based metal alloy preparation with tuned properties will be reported.

Nanostructured sol gel HA, ZnO, TiO2 and ZnO-HA dental coatings with tailored structure and mechanical properties

Nanostructured sol gel HA, ZnO, TiO2 and ZnO-HA dental coatings with tailored structure and mechanical properties will be developed

Results of bacteriological testing and recommendation for in-vivo and clinical application

Results of bacteriological testing and recommendation for invivo and clinical application will be published

Results of dental implant biocompatibility and toxicity

Results of dental implant biocompatibility and toxicity will be obtained

Prepared drafts of publications and conference theses, 40 scientific seminars

Drafts of publications and conference theses will be preparedForty scientific seminars will be organized

3D scaffolds formed by electrospinning and laser ablation methods

3D scaffolds formed by electrospinning and laser ablation methods will be formed over the metal alloy implants

Influence of surface type and topography on osteoblast and fibroblast attachment and proliferation and MSCs differentiation

Influence of surface type and topography on osteoblast and fibroblast attachment and proliferation and MSCs differentiation will be revealed

Results of early and late postoperative periods after the animal implantation and recommendation for clinical application

Results of early and late postoperative periods after the animal implantation and recommendation for clinical application will be summarized

Results of alloy’s mechanical testing, crystal structure, phase composition

Fundamental parameters of alloys will be calculated

Prototype of dental implant with advanced mechanical properties

Prototype of dental implant with advanced mechanical properties will be developed

Dissemination to scientific community at congresses, workshops, summer schools and outreach activities

Dissemination to scientific community at congresses, workshops, summer schools and outreach activities will be performed

Organized workshops, conference sections and summer schools

Organized workshops, conference sections and summer schools will be organized

Dissemination to wide auditory and public

Dissemination to wide auditory and public (schools, industry, general auditory) will be performed

Developed web page of the project

The web page of the project will be developed and moderated

New topics for Horizon 2020/Era-Net/Erasmus/bilateral project proposals

New topics for Horizon 2020/Era-Net/Erasmus/bilateral project proposals will be formulated

Publications

Hemostatic performance and biocompatibility of chitosan-based agents in experimental parenchymal bleeding

Author(s): Volodymyr Deineka; Oksana Sulaieva; N. Pernakov; Julia Radwan-Pragłowska; L. Janus; Viktoriia Korniienko; Ye. Husak; A. Yanovska; Iryna Liubchak; A. Yusupova; Marek Piątkowski; Alona Zlatska; Maksym Pogorielov
Published in: Materials Science and Engineering: C, Issue 12, 2021, ISSN 0928-4931
Publisher: Elsevier BV
DOI: 10.1016/j.msec.2020.111740

In Vitro Biological Characterization of Silver-Doped Anodic Oxide Coating on Titanium.

Author(s): Oleshko, Oleksandr Mykolaiovych; Liubchak, Iryna Volodymyrivna; Husak, Yevheniia Volodymyrivna; Корнiєнко, Вiкторiя Володимирiвна; Korniienko, Viktoriia Volodymyrivna; Yusupova, Aziza Farkhodivna; Oleshko, Tetiana Bohdanivna; Banasiuk, R.; Szkodo, M.; Matros-Taranets, I.; Kazek-Kęsik, A.; Simka, W.; Pohorielov, Maksym Volodymyrovych
Published in: Materials, Issue 16, 2020, ISSN 1996-1944
Publisher: MDPI Open Access Publishing
DOI: 10.3390/ma13194359

Complementary Effect of Non-Persistent Silver Nano-Architectures and Chlorhexidine on Infected Wound Healing

Author(s): Pernakov, Mykola Stanislavovych; Ermini, M.L.; Sulaieva, O.; Cassano, D.; Santucci, M.; Husak, Yevheniia Volodymyrivna; Корнiєнко, Вiкторiя Володимирiвна; Korniienko, Viktoriia Volodymyrivna; Giannone, G.; Yusupova, Aziza Farkhodivna; Liubchak, Iryna Volodymyrivna; Hristova, M.T.; Savchenko, A.; Holubnycha, Viktoriia Mykolaivna; Voliani, V.; Pohorielov, Maksym Volodymyrov
Published in: Biomedicines, Issue 11, 2021, ISSN 2227-9059
Publisher: MDPI
DOI: 10.3390/biomedicines9091215

Hemostatic and Tissue Regeneration Performance of Novel Electrospun Chitosan-Based Materials

Author(s): Deineka, Volodymyr Mykolaiovych; Sulaieva, O.; Pernakov, Mykola Stanislavovych; Корнiєнко, Вiкторiя Володимирiвна; Korniienko, Viktoriia Volodymyrivna; Husak, Yevheniia Volodymyrivna; Yanovska, Hanna Oleksandrivna; Yusupova, Aziza Farkhodivna; Tkachenko, Yuliia Anatoliivna; Kalinkevich, O.; Zlatska, A.; Pohorielov, Maksym Volodymyrovych
Published in: Biomedicines, Issue 1, 2021, ISSN 2227-9059
Publisher: MDPI
DOI: 10.3390/biomedicines9060588

Bioactivity Performance of Pure Mg after Plasma Electrolytic Oxidation in Silicate-Based Solutions.

Author(s): Yevheniia Husak; Joanna Michalska; Oleksandr Oleshko; Viktoriia Korniienko; Karlis Grundsteins; Bohdan Dryhval; Sahin Altundal; Sahin Altundal; Oleg Mishchenko; Roman Viter; Maksym Pogorielov; Wojciech Simka
Published in: Molecules, Vol 26, Iss 2094, p 2094 (2021), Issue 6, 2021, ISSN 1420-3049
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules26072094

Chitosan-Based Bioactive Hemostatic Agents with Antibacterial Properties—Synthesis and Characterization

Author(s): Julia Radwan-Pragłowska; Marek Piątkowski; Volodymyr Deineka; Łukasz Janus; Viktoriia Korniienko; E. V. Husak; Viktoria Holubnycha; Iryna Liubchak; Vyacheslav Zhurba; Aleksandra Sierakowska; Maksym Pogorielov; Dariusz Bogdal
Published in: Molecules, Vol 24, Iss 14, p 2629 (2019), Issue 17, 2019, ISSN 1420-3049
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules24142629

Degradation and In Vivo Response of Hydroxyapatite-Coated Mg Alloy

Author(s): Yevheniia Husak, Oleksandr Solodovnyk, Anna Yanovska, Yevhenii Kozik, Iryna Liubchak, Viktoriia Ivchenko, Oleg Mishchenko, Yevhen Zinchenko, Vladimir Kuznetsov, Maksym Pogorielov
Published in: Coatings, Issue 8/11, 2018, Page(s) 375, ISSN 2079-6412
Publisher: MDPI
DOI: 10.3390/coatings8110375

Chemical and Structural Characterization of Sandlasted Surface of Dental Implant using ZrO2 Particle with Different Shape

Author(s): Oleg Mishchenko, Vira Filatova, Mykhaylo Vasylyev, Volodymyr Deineka, Maksym Pogorielov
Published in: Coatings, Issue 9/4, 2019, Page(s) 223, ISSN 2079-6412
Publisher: MDPI
DOI: 10.3390/coatings9040223

Cell and tissue response to nanotextured Ti6Al4V and Zr implants using high-speed femtosecond laser-induced periodic surface structures

Author(s): Iaroslav Gnilitskyi, Maksym Pogorielov, Roman Viter, Ana Maria Ferraria, Ana Patrícia Carapeto, Olexandr Oleshko, Leonardo Orazi, Oleg Mishchenko
Published in: Nanomedicine: Nanotechnology, Biology and Medicine, 2019, Page(s) 102036, ISSN 1549-9634
Publisher: Elsevier BV
DOI: 10.1016/j.nano.2019.102036

Ag Nanoparticle-Decorated Oxide Coatings Formed via Plasma Electrolytic Oxidation on ZrNb Alloy

Author(s): Oleksandr Oleshko, Volodymyr Deineka V, Yevgeniia Husak, Viktoriia Korniienko, Oleg Mishchenko, Viktoriia Holubnycha, Marcin Pisarek, Joanna Michalska, Alicja Kazek-Kęsik, Agata Jakóbik-Kolon, Wojciech Simka, Maksym Pogorielov
Published in: Materials, Issue 12/22, 2019, Page(s) 3742, ISSN 1996-1944
Publisher: MDPI Open Access Publishing
DOI: 10.3390/ma12223742

New Zr-Ti-Nb Alloy for Medical Application: Development, Chemical and Mechanical Properties, and Biocompatibility

Author(s): Oleg Mishchenko, Oleksandr Ovchynnykov, Oleksii Kapustian, Maksym Pogorielov
Published in: Materials, Issue 13/6, 2020, Page(s) 1306, ISSN 1996-1944
Publisher: MDPI Open Access Publishing
DOI: 10.3390/ma13061306

Development, characterization and antimicrobial properties of silver nanoparticles loaded chitosan-alginate sponges for biomedical application

Author(s): A. Yanovska; Ye. Husak; Viktoriia Korniienko; Viktoriia Mykolaivna Holubnycha; Oleg Mishchenko; R. Banasiuk; Julia Radwan-Pragłowska; Marek Piątkowski; Łukasz Janus; Maksym Pogorielov
Published in: Journal of Materials Research, Issue 7, 2021, ISSN 2044-5326
Publisher: Springer Science+Business Media
DOI: 10.1557/s43578-021-00358-4

MXenes—A New Class of Two-Dimensional Materials: Structure, Properties and Potential Applications

Author(s): Maksym Pogorielov; Kateryna Smyrnova; Sergiy Kyrylenko; Oleksiy Gogotsi; Veronika Zahorodna; Alexander Pogrebnjak
Published in: Nanomaterials, Vol 11, Iss 3412, p 3412 (2021), Issue 25, 2021, ISSN 2079-4991
Publisher: MDPI
DOI: 10.3390/nano11123412

Formation of a Bacteriostatic Surface on ZrNb Alloy via Anodization in a Solution Containing Cu Nanoparticles

Author(s): Корнiєнко, Вiкторiя Володимирiвна; Korniienko, Viktoriia Volodymyrivna; Oleshko, Oleksandr Mykolaiovych; Husak, Yevheniia Volodymyrivna; Deineka, Volodymyr Mykolaiovych; Holubnycha, Viktoriia Mykolaivna; Mishchenko, O.; Kazek-Kęsik, A.; Jakobik-Kolon, A.; Pshenychnyi, Roman Mykolaiovych; Leśniak-Ziółkowska, K.; Kalinkevich, O.; Kalinkevich, A.; Pisarek, M.; Simka, W.;
Published in: Materials, Issue 2, 2020, ISSN 1996-1944
Publisher: MDPI Open Access Publishing
DOI: 10.3390/ma13183913

Biocompatibility and Antibacterial Properties of ZnO-Incorporated Anodic Oxide Coatings on TiZrNb Alloy.

Author(s): Oleksandr Oleshko; Yevheniia Husak; Viktoriia Korniienko; Roman Pshenychnyi; Yuliia Varava; Oksana Kalinkevich; Marcin Pisarek; Karlis Grundstains; Oksana Pogorielova; Oleg Mishchenko; Wojciech Simka; Roman Viter; Roman Viter; Maksym Pogorielov
Published in: Nanomaterials, Issue 14, 2020, ISSN 2079-4991
Publisher: MDPI
DOI: 10.3390/nano10122401

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