Osteoporosis constitutes a major public health concern; 1 in 3 women and 1 in 5 men are currently at risk for an osteoporotic fracture. In 2010, the economic burden of osteoporotic fractures in the European Union (EU) was approximately €37 billion. These costs are estimated to raise by 25% in the year 2025. Worldwide, by 2050, the incidence of osteoporotic fractures is expected to increase 310% in men and 240% in women compared to 1990. These estimates may indicate some ineffectiveness of currently available products aiming to prevent osteoporosis. In fact, the use of the marketed pharmacological agents for osteoporosis (e.g. bisphosphonates) has been decreasing in the EU. This is probably due to the reported side effects (as osteonecrosis of the jaw, atrial fibrillation and atypical femur fractures), and to the uncertainty of the positive long-term effects on bone formation. Calcium supplementation has also been reported to increase the risk of myocardial infarction. This means that there is a need for innovative products in order to reduce the current burden of osteoporosis. Bovine colostrum is a promising agent for osteoporosis prevention since it has natural components that seem to be directly involved in bone formation. As a nutracentical, colostrum confers an advantage over pharmacological agents since it can avoid the unpleasant side effects while inducing bone health benefits. The aim of COLOSTEO project is to produce new knowledge on the effects of bovine colostrum on bone formation and to create a nutracentical supplementation for osteoporosis prevention. To fulfil with this aim, COLOSTEO formed an intersectorial consortium involving academic and industrial partners. Academic partners have the scientific knowledge, facilities and experience to investigate the effects of colostrum on bone formation. Industrial partners have the expertise, experience and knowledge on manufacturing new products and marketing. Together, academia and industry will: a) Analyse bovine colostrum components and its consume safety; b) Investigate the effectiveness of bovine colostrum in preventing bone loss using an animal model (osteoporotic rat); c) Study the effects of the supplement on bone formation in human participants; d) Dissemination of the results; e) Create a business plan for product commercialisation.