Functionalized Magnetic Resonance Beacons for Enhanced Spectroscopy and Imaging

Información del proyecto

FunMagResBeacons

Identificador del acuerdo de subvención: 786707

DOI

10.3030/786707

Proyecto cerrado

Fecha de la firma de la CE 15 Mayo 2018

Fecha de inicio 1 Octubre 2018

Fecha de finalización 30 Septiembre 2024

Financiado con arreglo a

• EXCELLENT SCIENCE - European Research Council (ERC)

Coste total

€ 2 762 223,00

Aportación de la UE

€ 2 762 223,00

Coordinado por

UNIVERSITY OF SOUTHAMPTON
United Kingdom

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Publicaciones

Peer reviewed articles (33)

Weak nuclear spin singlet relaxation mechanisms revealed by experiment and computation

Autores: Alexej Jerschow; Boris B. Kharkov; Xue-You Duan; Jyrki Rantaharju; Mohamed Sabba; Malcolm H. Levitt; James W. Canary
Publicado en: Physical Chemistry Chemical Physics, Edición 1, 2022, Página(s) 7531-7538, ISSN 1463-9084
Editor: RSC
DOI: 10.1039/d1cp05537b

A Solid-State Intramolecular Wittig Reaction Enables Efficient Synthesis of Endofullerenes Including Ne@C60, 3He@C60, and HD@C60

Autores: Gabriela Hoffman; Mark C. Walkey; John Gräsvik; George Razvan Bacanu; Shamim Alom; Sally Bloodworth; Mark E. Light; Malcolm H. Levitt; Richard J. Whitby
Publicado en: Angewandte Chemie International Edition, Edición 1, 2021, ISSN 1521-3773
Editor: Wiley-VCH
DOI: 10.1002/ange.202100817

Cross-correlated relaxation in the NMR of near-equivalent spin pairs: Longitudinal relaxation and long-lived singlet order

Autores: James W. Whipham, Mohamed Sabba, Laurynas Dagys, Gamal Moustafa, Christian Bengs, Malcolm H. Levitt
Publicado en: The Journal of Chemical Physics, Edición 161, 2024, ISSN 0021-9606
Editor: American Institute of Physics
DOI: 10.1063/5.0213997

15N hyperpolarisation of the antiprotozoal drug ornidazole by Signal Amplification By Reversible Exchange in aqueous medium

Autores: Wissam Iali; Gamal A. I. Moustafa; Gamal A. I. Moustafa; Laurynas Dagys; Soumya Singha Roy
Publicado en: Magnetic Resonance in Chemistry, Edición 2, 2021, Página(s) 1199-1207, ISSN 1097-458X
Editor: Wiley
DOI: 10.1002/mrc.5144

Hyperpolarised [2-¹³C]-pyruvate by ¹³C SABRE in an acetone/water mixture

Autores: Oksana A. Bondar, Gamal A. I. Moustafa, Thomas B. R. Robertson
Publicado en: The Analyst, Edición 149, 2024, Página(s) 5668-5674, ISSN 0003-2654
Editor: Royal Society of Chemistry
DOI: 10.1039/d4an01005a

Efficient Parahydrogen-Induced ¹³C Hyperpolarization on a Microfluidic Device

Autores: Sylwia J. Barker, Laurynas Dagys, Malcolm H. Levitt, Marcel Utz
Publicado en: Journal of the American Chemical Society, Edición 146, 2024, Página(s) 18379-18386, ISSN 0002-7863
Editor: American Chemical Society
DOI: 10.1021/jacs.4c03271

<i>Geminal</i> parahydrogen-induced polarization: accumulating long-lived singlet order on methylene proton pairs

Autores: Laurynas Dagys, Barbara Ripka, Markus Leutzsch, Gamal A. I. Moustafa, James Eills, Johannes F. P. Colell, Malcolm H. Levitt
Publicado en: Magnetic Resonance, Edición 1/2, 2020, Página(s) 175-186, ISSN 2699-0016
Editor: Copernicus
DOI: 10.5194/mr-1-175-2020

³¹P spin–lattice and singlet order relaxation mechanisms in pyrophosphate studied by isotopic substitution, field shuttling NMR, and molecular dynamics simulation

Autores: David E. Korenchan; Jiaqi Lu; Mohamed Sabba; Laurynas Dagys; Lynda J. Brown; Malcolm H. Levitt; Alexej Jerschow
Publicado en: Phys. Chem. Chem. Phys., Edición 1, 2022, Página(s) 24238-24245, ISSN 1463-9084
Editor: RSC
DOI: 10.1039/d2cp03801c

Singlet-Contrast Magnetic Resonance Imaging: Unlocking Hyperpolarization with Metabolism*.

Autores: James Eills; Eleonora Cavallari; Raphael Kircher; Ginevra Di Matteo; Carla Carrera; Laurynas Dagys; Malcolm H. Levitt; Konstantin L. Ivanov; Silvio Aime; Francesca Reineri; Kerstin Münnemann; Dmitry Budker; Gerd Buntkowsky; Stephan Knecht
Publicado en: Angewandte Chemie / International edition, Edición 1, 2021, Página(s) 6791-6798, ISSN 1521-3773
Editor: Wiley-VCH
DOI: 10.26434/chemrxiv.12863639.v2

Cross-correlation effects in the solution NMR spectra of near-equivalent spin-1/2 pairs

Autores: James W. Whipham, Gamal A. I. Moustafa, Mohamed Sabba, Weidong Gong, Christian Bengs, Malcolm H. Levitt
Publicado en: The Journal of Chemical Physics, Edición 157, 2023, ISSN 0021-9606
Editor: American Institute of Physics
DOI: 10.1063/5.0107221

Symmetry-based singlettriplet excitation in solution nuclear magnetic resonance

Autores: Mohamed Sabba, Nino Wili, Christian Bengs, James W. Whipham, Lynda J. Brown, Malcolm H. Levitt
Publicado en: The Journal of Chemical Physics, Edición 157, 2024, ISSN 0021-9606
Editor: American Institute of Physics
DOI: 10.1063/5.0103122

Centralizer theory for long-lived spin states.

Autores: Christian Bengs
Publicado en: J. Chem. Phys., Edición 1, 2021, Página(s) 244107, ISSN 0021-9606
Editor: American Institute of Physics
DOI: 10.1063/5.0050419

¹H-enhanced ¹⁰³Rh NMR spectroscopy and relaxometry of ¹⁰³Rh(acac)₃ in solution

Autores: Harry Harbor-Collins, Mohamed Sabba, Markus Leutzsch, Malcolm H. Levitt
Publicado en: Magnetic Resonance, Edición 5, 2024, Página(s) 121-129, ISSN 2699-0016
Editor: Copernicus
DOI: 10.5194/mr-5-121-2024

Direct Production of a Hyperpolarized Metabolite on a Microfluidic Chip

Autores: Sylwia J. Barker, Laurynas Dagys, William Hale, Barbara Ripka, James Eills, Manvendra Sharma, Malcolm H. Levitt, Marcel Utz
Publicado en: Analytical Chemistry, Edición 94, 2023, Página(s) 3260-3267, ISSN 0003-2700
Editor: American Chemical Society
DOI: 10.1021/acs.analchem.1c05030

Deuteron-Decoupled Singlet NMR in Low Magnetic Fields: Application to the Hyperpolarization of Succinic Acid.

Autores: Laurynas Dagys; Christian Bengs; Gamal A. I. Moustafa; Malcolm H. Levitt
Publicado en: ChemPhysChem, Edición 1, 2022, Página(s) e202200274, ISSN 1439-7641
Editor: Wiley
DOI: 10.1002/cphc.202200274

Low-frequency excitation of singlet-triplet transitions. Application to nuclear hyperpolarization.

Autores: Laurynas Dagys; Christian Bengs; Malcolm H. Levitt
Publicado en: The Journal of Chemical Physics, Edición 1, 2021, Página(s) 154201, ISSN 0021-9606
Editor: American Institute of Physics
DOI: 10.1063/5.0065863

The 103Rh NMR spectroscopy and relaxometry of the rhodium formate paddlewheel complex

Autores: Harry Harbor-Collins, Mohamed Sabba, Gamal Moustafa, Bonifac Legrady, Murari Soundararajan, Markus Leutzsch, Malcolm H. Levitt
Publicado en: The Journal of Chemical Physics, Edición 159, 2023, ISSN 0021-9606
Editor: American Institute of Physics
DOI: 10.1063/5.0165830

Hyperpolarization read-out through rapidly rotating fields in the zero- and low-field regime

Autores: Laurynas Dagys; Christian Bengs
Publicado en: Physical Chemistry Chemical Physics, Edición 1, 2022, Página(s) 8321-8328, ISSN 1463-9084
Editor: RSC
DOI: 10.48550/arxiv.2202.04604

Nuclear Singlet Relaxation by Chemical Exchange

Autores: Christian Bengs; Laurynas Dagys; Gamal A. I. Moustafa; James W. Whipham; Mohamed Sabba; Alexey S. Kiryutin; Konstantin L. Ivanov; Malcolm H. Levitt
Publicado en: The Journal of Chemical Physics, Edición 1, 2021, Página(s) 124311, ISSN 0021-9606
Editor: American Institute of Physics
DOI: 10.1063/5.0066182

Hyperpolarized long-lived nuclear spin states in monodeuterated methyl groups

Autores: Stuart J. Elliott, Benno Meier, Basile Vuichoud, Gabriele Stevanato, Lynda J. Brown, Javier Alonso-Valdesueiro, Lyndon Emsley, Sami Jannin, Malcolm H. Levitt
Publicado en: Physical Chemistry Chemical Physics, Edición 20/15, 2018, Página(s) 9755-9759, ISSN 1463-9076
Editor: Royal Society of Chemistry
DOI: 10.1039/c8cp00253c

First Synthesis and Characterization of CH 4 @C 60

Autores: Sally Bloodworth, Gabriela Sitinova, Shamim Alom, Sara Vidal, George R. Bacanu, Stuart J. Elliott, Mark E. Light, Julie M. Herniman, G. John Langley, Malcolm H. Levitt, Richard J. Whitby
Publicado en: Angewandte Chemie International Edition, Edición 58/15, 2019, Página(s) 5038-5043, ISSN 1433-7851
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201900983

Long live the singlet state!

Autores: Malcolm H. Levitt
Publicado en: Journal of Magnetic Resonance, Edición 306, 2019, Página(s) 69-74, ISSN 1090-7807
Editor: Academic Press
DOI: 10.1016/j.jmr.2019.07.029

Fast destruction of singlet order in NMR experiments

Autores: Bogdan A. Rodin, Kirill F. Sheberstov, Alexey S. Kiryutin, Lynda J. Brown, Richard C. D. Brown, Mohamed Sabba, Malcolm H. Levitt, Alexandra V. Yurkovskaya, Konstantin L. Ivanov
Publicado en: The Journal of Chemical Physics, Edición 151/23, 2019, Página(s) 234203, ISSN 0021-9606
Editor: American Institute of Physics
DOI: 10.1063/1.5131730

A master equation for spin systems far from equilibrium

Autores: Christian Bengs, Malcolm H. Levitt
Publicado en: Journal of Magnetic Resonance, Edición 310, 2020, Página(s) 106645, ISSN 1090-7807
Editor: Academic Press
DOI: 10.1016/j.jmr.2019.106645

Generalised magnetisation-to-singlet-order transfer in nuclear magnetic resonance

Autores: Christian Bengs, Mohamed Sabba, Alexej Jerschow, Malcolm H. Levitt
Publicado en: Physical Chemistry Chemical Physics, Edición 22/17, 2020, Página(s) 9703-9712, ISSN 1463-9076
Editor: Royal Society of Chemistry
DOI: 10.1039/d0cp00935k

Algorithmic cooling of nuclear spins using long-lived singlet order

Autores: Bogdan A. Rodin, Christian Bengs, Alexey S. Kiryutin, Kirill F. Sheberstov, Lynda J. Brown, Richard C. D. Brown, Alexandra V. Yurkovskaya, Konstantin L. Ivanov, Malcolm H. Levitt
Publicado en: The Journal of Chemical Physics, Edición 152/16, 2020, Página(s) 164201, ISSN 0021-9606
Editor: American Institute of Physics
DOI: 10.1063/5.0006742

Hyperpolarization and the physical boundary of Liouville space

Autores: Malcolm H. Levitt, Christian Bengs
Publicado en: Magnetic Resonance, Edición 2, 2021, Página(s) 395-407, ISSN 2699-0016
Editor: Copernicus
DOI: 10.5194/mr-2-395-2021

NMR spectroscopy of a 18O-labeled rhodium paddlewheel complex: Isotope shifts, 103Rh103Rh spinspin coupling, and 103Rh singlet NMR

Autores: Harry Harbor-Collins, Mohamed Sabba, Christian Bengs, Gamal Moustafa, Markus Leutzsch, Malcolm H. Levitt
Publicado en: The Journal of Chemical Physics, Edición 160, 2024, ISSN 0021-9606
Editor: American Institute of Physics
DOI: 10.1063/5.0182233

Synthesis of Ar@C60 using molecular surgery.

Autores: Sally Bloodworth; Gabriela Hoffman; Mark C. Walkey; George Razvan Bacanu; Julie Herniman; Malcolm H. Levitt; Richard J. Whitby
Publicado en: Chemical Communications, Edición 1, 2020, Página(s) 10521-10524, ISSN 1364-548X
Editor: RSC
DOI: 10.1039/d0cc04201c

Tuning of pH enables carbon-13 hyperpolarization of oxalates by SABRE.

Autores: Soumya S. Roy; Wissam Iali; Gamal A. I. Moustafa; Malcolm H. Levitt
Publicado en: Chem. Commun., Edición 1, 2022, Página(s) 2291-2294, ISSN 1364-548X
Editor: RSC
DOI: 10.1039/d1cc06973j

An Internuclear J -Coupling of 3 He Induced by Molecular Confinement

Autores: George Razvan Bacanu, Jyrki Rantaharju, Gabriela Hoffman, Mark C. Walkey, Sally Bloodworth, Maria Concistrè, Richard J. Whitby, Malcolm H. Levitt
Publicado en: Journal of the American Chemical Society, Edición 142/40, 2020, Página(s) 16926-16929, ISSN 0002-7863
Editor: American Chemical Society
DOI: 10.1021/jacs.0c08586

The AharonovAnandan phase and geometric double-quantum excitation in strongly coupled nuclear spin pairs

Autores: Christian Bengs, Mohamed Sabba, Malcolm H. Levitt
Publicado en: The Journal of Chemical Physics, Edición 158, 2023, ISSN 0021-9606
Editor: American Institute of Physics
DOI: 10.1063/5.0138146

Rapid hyperpolarization and purification of the metabolite fumarate in aqueous solution

Autores: Stephan Knecht, John W. Blanchard, Danila Barskiy, Eleonora Cavallari, Laurynas Dagys, Erik Van Dyke, Maksim Tsukanov, Bea Bliemel, Kerstin Münnemann, Silvio Aime, Francesca Reineri, Malcolm H. Levitt, Gerd Buntkowsky, Alexander Pines, Peter Blümler, Dmitry Budker, James Eills
Publicado en: Proceedings of the National Academy of Sciences, Edición 118/13, 2021, Página(s) e2025383118, ISSN 0027-8424
Editor: National Academy of Sciences
DOI: 10.1073/pnas.2025383118