Functionalized Magnetic Resonance Beacons for Enhanced Spectroscopy and Imaging

Informazioni relative al progetto

FunMagResBeacons

ID dell’accordo di sovvenzione: 786707

DOI

10.3030/786707

Progetto chiuso

Data della firma CE 15 Maggio 2018

Data di avvio 1 Ottobre 2018

Data di completamento 30 Settembre 2024

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale

€ 2 762 223,00

Contributo UE

€ 2 762 223,00

Coordinato da

UNIVERSITY OF SOUTHAMPTON
United Kingdom

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Pubblicazioni

Peer reviewed articles (33)

Weak nuclear spin singlet relaxation mechanisms revealed by experiment and computation

Autori: Alexej Jerschow; Boris B. Kharkov; Xue-You Duan; Jyrki Rantaharju; Mohamed Sabba; Malcolm H. Levitt; James W. Canary
Pubblicato in: Physical Chemistry Chemical Physics, Numero 1, 2022, Pagina/e 7531-7538, ISSN 1463-9084
Editore: RSC
DOI: 10.1039/d1cp05537b

A Solid-State Intramolecular Wittig Reaction Enables Efficient Synthesis of Endofullerenes Including Ne@C60, 3He@C60, and HD@C60

Autori: Gabriela Hoffman; Mark C. Walkey; John Gräsvik; George Razvan Bacanu; Shamim Alom; Sally Bloodworth; Mark E. Light; Malcolm H. Levitt; Richard J. Whitby
Pubblicato in: Angewandte Chemie International Edition, Numero 1, 2021, ISSN 1521-3773
Editore: Wiley-VCH
DOI: 10.1002/ange.202100817

Cross-correlated relaxation in the NMR of near-equivalent spin pairs: Longitudinal relaxation and long-lived singlet order

Autori: James W. Whipham, Mohamed Sabba, Laurynas Dagys, Gamal Moustafa, Christian Bengs, Malcolm H. Levitt
Pubblicato in: The Journal of Chemical Physics, Numero 161, 2024, ISSN 0021-9606
Editore: American Institute of Physics
DOI: 10.1063/5.0213997

15N hyperpolarisation of the antiprotozoal drug ornidazole by Signal Amplification By Reversible Exchange in aqueous medium

Autori: Wissam Iali; Gamal A. I. Moustafa; Gamal A. I. Moustafa; Laurynas Dagys; Soumya Singha Roy
Pubblicato in: Magnetic Resonance in Chemistry, Numero 2, 2021, Pagina/e 1199-1207, ISSN 1097-458X
Editore: Wiley
DOI: 10.1002/mrc.5144

Hyperpolarised [2-¹³C]-pyruvate by ¹³C SABRE in an acetone/water mixture

Autori: Oksana A. Bondar, Gamal A. I. Moustafa, Thomas B. R. Robertson
Pubblicato in: The Analyst, Numero 149, 2024, Pagina/e 5668-5674, ISSN 0003-2654
Editore: Royal Society of Chemistry
DOI: 10.1039/d4an01005a

Efficient Parahydrogen-Induced ¹³C Hyperpolarization on a Microfluidic Device

Autori: Sylwia J. Barker, Laurynas Dagys, Malcolm H. Levitt, Marcel Utz
Pubblicato in: Journal of the American Chemical Society, Numero 146, 2024, Pagina/e 18379-18386, ISSN 0002-7863
Editore: American Chemical Society
DOI: 10.1021/jacs.4c03271

<i>Geminal</i> parahydrogen-induced polarization: accumulating long-lived singlet order on methylene proton pairs

Autori: Laurynas Dagys, Barbara Ripka, Markus Leutzsch, Gamal A. I. Moustafa, James Eills, Johannes F. P. Colell, Malcolm H. Levitt
Pubblicato in: Magnetic Resonance, Numero 1/2, 2020, Pagina/e 175-186, ISSN 2699-0016
Editore: Copernicus
DOI: 10.5194/mr-1-175-2020

³¹P spin–lattice and singlet order relaxation mechanisms in pyrophosphate studied by isotopic substitution, field shuttling NMR, and molecular dynamics simulation

Autori: David E. Korenchan; Jiaqi Lu; Mohamed Sabba; Laurynas Dagys; Lynda J. Brown; Malcolm H. Levitt; Alexej Jerschow
Pubblicato in: Phys. Chem. Chem. Phys., Numero 1, 2022, Pagina/e 24238-24245, ISSN 1463-9084
Editore: RSC
DOI: 10.1039/d2cp03801c

Singlet-Contrast Magnetic Resonance Imaging: Unlocking Hyperpolarization with Metabolism*.

Autori: James Eills; Eleonora Cavallari; Raphael Kircher; Ginevra Di Matteo; Carla Carrera; Laurynas Dagys; Malcolm H. Levitt; Konstantin L. Ivanov; Silvio Aime; Francesca Reineri; Kerstin Münnemann; Dmitry Budker; Gerd Buntkowsky; Stephan Knecht
Pubblicato in: Angewandte Chemie / International edition, Numero 1, 2021, Pagina/e 6791-6798, ISSN 1521-3773
Editore: Wiley-VCH
DOI: 10.26434/chemrxiv.12863639.v2

Cross-correlation effects in the solution NMR spectra of near-equivalent spin-1/2 pairs

Autori: James W. Whipham, Gamal A. I. Moustafa, Mohamed Sabba, Weidong Gong, Christian Bengs, Malcolm H. Levitt
Pubblicato in: The Journal of Chemical Physics, Numero 157, 2023, ISSN 0021-9606
Editore: American Institute of Physics
DOI: 10.1063/5.0107221

Symmetry-based singlettriplet excitation in solution nuclear magnetic resonance

Autori: Mohamed Sabba, Nino Wili, Christian Bengs, James W. Whipham, Lynda J. Brown, Malcolm H. Levitt
Pubblicato in: The Journal of Chemical Physics, Numero 157, 2024, ISSN 0021-9606
Editore: American Institute of Physics
DOI: 10.1063/5.0103122

Centralizer theory for long-lived spin states.

Autori: Christian Bengs
Pubblicato in: J. Chem. Phys., Numero 1, 2021, Pagina/e 244107, ISSN 0021-9606
Editore: American Institute of Physics
DOI: 10.1063/5.0050419

¹H-enhanced ¹⁰³Rh NMR spectroscopy and relaxometry of ¹⁰³Rh(acac)₃ in solution

Autori: Harry Harbor-Collins, Mohamed Sabba, Markus Leutzsch, Malcolm H. Levitt
Pubblicato in: Magnetic Resonance, Numero 5, 2024, Pagina/e 121-129, ISSN 2699-0016
Editore: Copernicus
DOI: 10.5194/mr-5-121-2024

Direct Production of a Hyperpolarized Metabolite on a Microfluidic Chip

Autori: Sylwia J. Barker, Laurynas Dagys, William Hale, Barbara Ripka, James Eills, Manvendra Sharma, Malcolm H. Levitt, Marcel Utz
Pubblicato in: Analytical Chemistry, Numero 94, 2023, Pagina/e 3260-3267, ISSN 0003-2700
Editore: American Chemical Society
DOI: 10.1021/acs.analchem.1c05030

Deuteron-Decoupled Singlet NMR in Low Magnetic Fields: Application to the Hyperpolarization of Succinic Acid.

Autori: Laurynas Dagys; Christian Bengs; Gamal A. I. Moustafa; Malcolm H. Levitt
Pubblicato in: ChemPhysChem, Numero 1, 2022, Pagina/e e202200274, ISSN 1439-7641
Editore: Wiley
DOI: 10.1002/cphc.202200274

Low-frequency excitation of singlet-triplet transitions. Application to nuclear hyperpolarization.

Autori: Laurynas Dagys; Christian Bengs; Malcolm H. Levitt
Pubblicato in: The Journal of Chemical Physics, Numero 1, 2021, Pagina/e 154201, ISSN 0021-9606
Editore: American Institute of Physics
DOI: 10.1063/5.0065863

The 103Rh NMR spectroscopy and relaxometry of the rhodium formate paddlewheel complex

Autori: Harry Harbor-Collins, Mohamed Sabba, Gamal Moustafa, Bonifac Legrady, Murari Soundararajan, Markus Leutzsch, Malcolm H. Levitt
Pubblicato in: The Journal of Chemical Physics, Numero 159, 2023, ISSN 0021-9606
Editore: American Institute of Physics
DOI: 10.1063/5.0165830

Hyperpolarization read-out through rapidly rotating fields in the zero- and low-field regime

Autori: Laurynas Dagys; Christian Bengs
Pubblicato in: Physical Chemistry Chemical Physics, Numero 1, 2022, Pagina/e 8321-8328, ISSN 1463-9084
Editore: RSC
DOI: 10.48550/arxiv.2202.04604

Nuclear Singlet Relaxation by Chemical Exchange

Autori: Christian Bengs; Laurynas Dagys; Gamal A. I. Moustafa; James W. Whipham; Mohamed Sabba; Alexey S. Kiryutin; Konstantin L. Ivanov; Malcolm H. Levitt
Pubblicato in: The Journal of Chemical Physics, Numero 1, 2021, Pagina/e 124311, ISSN 0021-9606
Editore: American Institute of Physics
DOI: 10.1063/5.0066182

Hyperpolarized long-lived nuclear spin states in monodeuterated methyl groups

Autori: Stuart J. Elliott, Benno Meier, Basile Vuichoud, Gabriele Stevanato, Lynda J. Brown, Javier Alonso-Valdesueiro, Lyndon Emsley, Sami Jannin, Malcolm H. Levitt
Pubblicato in: Physical Chemistry Chemical Physics, Numero 20/15, 2018, Pagina/e 9755-9759, ISSN 1463-9076
Editore: Royal Society of Chemistry
DOI: 10.1039/c8cp00253c

First Synthesis and Characterization of CH 4 @C 60

Autori: Sally Bloodworth, Gabriela Sitinova, Shamim Alom, Sara Vidal, George R. Bacanu, Stuart J. Elliott, Mark E. Light, Julie M. Herniman, G. John Langley, Malcolm H. Levitt, Richard J. Whitby
Pubblicato in: Angewandte Chemie International Edition, Numero 58/15, 2019, Pagina/e 5038-5043, ISSN 1433-7851
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201900983

Long live the singlet state!

Autori: Malcolm H. Levitt
Pubblicato in: Journal of Magnetic Resonance, Numero 306, 2019, Pagina/e 69-74, ISSN 1090-7807
Editore: Academic Press
DOI: 10.1016/j.jmr.2019.07.029

Fast destruction of singlet order in NMR experiments

Autori: Bogdan A. Rodin, Kirill F. Sheberstov, Alexey S. Kiryutin, Lynda J. Brown, Richard C. D. Brown, Mohamed Sabba, Malcolm H. Levitt, Alexandra V. Yurkovskaya, Konstantin L. Ivanov
Pubblicato in: The Journal of Chemical Physics, Numero 151/23, 2019, Pagina/e 234203, ISSN 0021-9606
Editore: American Institute of Physics
DOI: 10.1063/1.5131730

A master equation for spin systems far from equilibrium

Autori: Christian Bengs, Malcolm H. Levitt
Pubblicato in: Journal of Magnetic Resonance, Numero 310, 2020, Pagina/e 106645, ISSN 1090-7807
Editore: Academic Press
DOI: 10.1016/j.jmr.2019.106645

Generalised magnetisation-to-singlet-order transfer in nuclear magnetic resonance

Autori: Christian Bengs, Mohamed Sabba, Alexej Jerschow, Malcolm H. Levitt
Pubblicato in: Physical Chemistry Chemical Physics, Numero 22/17, 2020, Pagina/e 9703-9712, ISSN 1463-9076
Editore: Royal Society of Chemistry
DOI: 10.1039/d0cp00935k

Algorithmic cooling of nuclear spins using long-lived singlet order

Autori: Bogdan A. Rodin, Christian Bengs, Alexey S. Kiryutin, Kirill F. Sheberstov, Lynda J. Brown, Richard C. D. Brown, Alexandra V. Yurkovskaya, Konstantin L. Ivanov, Malcolm H. Levitt
Pubblicato in: The Journal of Chemical Physics, Numero 152/16, 2020, Pagina/e 164201, ISSN 0021-9606
Editore: American Institute of Physics
DOI: 10.1063/5.0006742

Hyperpolarization and the physical boundary of Liouville space

Autori: Malcolm H. Levitt, Christian Bengs
Pubblicato in: Magnetic Resonance, Numero 2, 2021, Pagina/e 395-407, ISSN 2699-0016
Editore: Copernicus
DOI: 10.5194/mr-2-395-2021

NMR spectroscopy of a 18O-labeled rhodium paddlewheel complex: Isotope shifts, 103Rh103Rh spinspin coupling, and 103Rh singlet NMR

Autori: Harry Harbor-Collins, Mohamed Sabba, Christian Bengs, Gamal Moustafa, Markus Leutzsch, Malcolm H. Levitt
Pubblicato in: The Journal of Chemical Physics, Numero 160, 2024, ISSN 0021-9606
Editore: American Institute of Physics
DOI: 10.1063/5.0182233

Synthesis of Ar@C60 using molecular surgery.

Autori: Sally Bloodworth; Gabriela Hoffman; Mark C. Walkey; George Razvan Bacanu; Julie Herniman; Malcolm H. Levitt; Richard J. Whitby
Pubblicato in: Chemical Communications, Numero 1, 2020, Pagina/e 10521-10524, ISSN 1364-548X
Editore: RSC
DOI: 10.1039/d0cc04201c

Tuning of pH enables carbon-13 hyperpolarization of oxalates by SABRE.

Autori: Soumya S. Roy; Wissam Iali; Gamal A. I. Moustafa; Malcolm H. Levitt
Pubblicato in: Chem. Commun., Numero 1, 2022, Pagina/e 2291-2294, ISSN 1364-548X
Editore: RSC
DOI: 10.1039/d1cc06973j

An Internuclear J -Coupling of 3 He Induced by Molecular Confinement

Autori: George Razvan Bacanu, Jyrki Rantaharju, Gabriela Hoffman, Mark C. Walkey, Sally Bloodworth, Maria Concistrè, Richard J. Whitby, Malcolm H. Levitt
Pubblicato in: Journal of the American Chemical Society, Numero 142/40, 2020, Pagina/e 16926-16929, ISSN 0002-7863
Editore: American Chemical Society
DOI: 10.1021/jacs.0c08586

The AharonovAnandan phase and geometric double-quantum excitation in strongly coupled nuclear spin pairs

Autori: Christian Bengs, Mohamed Sabba, Malcolm H. Levitt
Pubblicato in: The Journal of Chemical Physics, Numero 158, 2023, ISSN 0021-9606
Editore: American Institute of Physics
DOI: 10.1063/5.0138146

Rapid hyperpolarization and purification of the metabolite fumarate in aqueous solution

Autori: Stephan Knecht, John W. Blanchard, Danila Barskiy, Eleonora Cavallari, Laurynas Dagys, Erik Van Dyke, Maksim Tsukanov, Bea Bliemel, Kerstin Münnemann, Silvio Aime, Francesca Reineri, Malcolm H. Levitt, Gerd Buntkowsky, Alexander Pines, Peter Blümler, Dmitry Budker, James Eills
Pubblicato in: Proceedings of the National Academy of Sciences, Numero 118/13, 2021, Pagina/e e2025383118, ISSN 0027-8424
Editore: National Academy of Sciences
DOI: 10.1073/pnas.2025383118