Molecular machines based on coiled-coil protein origami

Publicaciones

A nanobody toolbox targeting dimeric coiled-coilmodules for functionalization of designedprotein origami structures

Autores: Andreja Majerle, San Hadži, Jana Aupič, Tadej Satler, Fabio Lapenta, Žiga Strmšek, Jurij Lah, Remy Loris, and Roman Jerala,
Publicado en: Proc Natl Acad Sci USA, 2021, ISSN 1091-6490
Editor: National Academy of Science
DOI: 10.1073/pnas.2021899118

Coiled-coil heterodimer-based recruitment of an exonuclease to CRISPR/Cas for enhanced gene editing

Autores: Duško Lainšček, Vida Forstnerič, Veronika Mikolič, Špela Malenšek, Peter Pečan, Mojca Benčina, Matjaž Sever, Helena Podgornik & Roman Jerala
Publicado en: Nature Communications, 2022, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-022-31386-1

A tunable orthogonal coiled-coil interaction toolbox for engineering mammalian cells

Autores: Tina Lebar, Duško Lainšček, Estera Merljak, Jana Aupič, Roman Jerala
Publicado en: Nature Chemical Biology, 2020, ISSN 1552-4450
Editor: Nature Publishing Group
DOI: 10.1038/s41589-019-0443-y

Design of fast proteolysis-based signaling and logic circuits in mammalian cells

Autores: Tina Fink, Jan Lonzarić, Arne Praznik, Tjaša Plaper, Estera Merljak, Katja Leben, Nina Jerala, Tina Lebar, Žiga Strmšek, Fabio Lapenta, Mojca Benčina, Roman Jerala
Publicado en: Nature Chemical Biology, Edición 15/2, 2019, Página(s) 115-122, ISSN 1552-4450
Editor: Nature Publishing Group
DOI: 10.1038/s41589-018-0181-6

Regulation of protein secretion through chemicalregulation of endoplasmic reticulum retentionsignal cleavage

Autores: Arne Praznik, Tina Fink, Nik Franko, Jan Lonzarić, Mojca Benčina, Nina Jerala, Tjaša Plaper, Samo Roškar & Roman Jerala
Publicado en: Nature Communications, 2022, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-022-28971-9

A Nanoscaffolded Spike-RBD Vaccine Provides Protectionagainst SARS-CoV-2 with Minimal Anti-Scaffold Response

Autores: Duško Lainšček, Tina Fink, Vida Forstnerič, Iva Hafner-Bratkovič, Sara Orehek, Žiga Strmšek, Mateja Manček-Keber, Peter Pečan, Hana Esih, Špela Malenšek, Jana Aupič, Petra Dekleva, Tjaša Plaper, Sara Vidmar, Lucija Kadunc, Mojca Benčina, Neža Omersa, Gregor Anderluh, Florence Pojer, Kelvin Lau, David Hacker, Bruno E. Correia, David Peterhoff, Ralf Wagner, Valter Bergant, Alexander H
Publicado en: Vaccines, 2021, ISSN 2076-393X
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/vaccines9050431

Metal ion–regulated assembly of designedmodular protein cages

Autores: Jana Aupič, Fabio Lapenta, Žiga Strmšek, Estera Merljak, Tjaša Plaper, Roman Jerala
Publicado en: Science Advances, 2022, ISSN 2375-2548
Editor: AAAS
DOI: 10.1126/sciadv.abm8243

Designed folding pathway of modular coiled-coil-based proteins

Autores: Jana Aupič, Žiga Strmšek, Fabio Lapenta, David Pahovnik, Tomaž Pisanski, Igor Drobnak, Ajasja Ljubetič, Roman Jerala
Publicado en: Nature Communications, Edición 12/1, 2021, Página(s) 1-12, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-021-21185-5

Self-assembly and regulation of protein cages from pre-organised coiled-coil modules

Autores: Fabio Lapenta, Jana Aupič, Marco Vezzoli, Žiga Strmšek, Stefano Da Vela, Dmitri I. Svergun, José María Carazo, Roberto Melero, Roman Jerala
Publicado en: Nature Communications, Edición 12/1, 2021, Página(s) 1-12, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-021-21184-6

Derechos de propiedad intelectual

COILED-COIL MEDIATED TETHERING OF CRISPR-CAS AND EXONUCLEASES FOR ENHANCED GENOME EDITING

Número de solicitud/publicación: 19 192490
Fecha: 2019-08-20

COILED-COIL MEDIATED TETHERING OF CRISPR-CAS AND EXONUCLEASES FOR ENHANCED GENOME EDITING

Número de solicitud/publicación: 19 192490
Fecha: 2019-08-20

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Publicaciones

Derechos de propiedad intelectual

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