Mechanisms of vascular maturation and quiescence during development, homeostasis and aging

Project Information

AngioMature

Grant agreement ID: 787181

DOI 10.3030/787181

EC signature date 10 July 2018

Start date 1 August 2018

End date 31 October 2024

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 2 338 918,00

EU contribution € 2 338 918,00

Coordinated by

RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG
Germany

Deliverables

Open Research Data Pilot (1)

Data Management Plan (DMP)

Publications

Peer reviewed articles (5)

A spatial vascular transcriptomic, proteomic, and phosphoproteomic atlas unveils an angiocrine Tie–Wnt signaling axis in the liver

Author(s): Donato Inverso, Jingjing Shi, Ki Hong Lee, Moritz Jakab, Shani Ben-Moshe, Shubhada R. Kulkarni, Martin Schneider, Guanxiong Wang, Marziyeh Komeili, Paula Argos Vélez, Maria Riedel, Carleen Spegg, Thomas Ruppert, Christine Schaeffer-Reiss, Dominic Helm, Indrabahadur Singh, Michael Boutros, Sudhakar Chintharlapalli, Mathias Heikenwalder, Shalev Itzkovitz, Hellmut G. Augustin
Published in: Developmental Cell, Issue 56/11, 2021, Page(s) 1677-1693.e10, ISSN 1534-5807
Publisher: Cell Press
DOI: 10.1016/j.devcel.2021.05.001

Angiodiversity and organotypic functions of sinusoidal endothelial cells

Author(s): Philipp-Sebastian Koch, Ki Hong Lee, Sergij Goerdt, Hellmut G. Augustin
Published in: Angiogenesis, Issue 24/2, 2021, Page(s) 289-310, ISSN 0969-6970
Publisher: Kluwer Academic Publishers
DOI: 10.1007/s10456-021-09780-y

Endothelial cell fitness dictates the source of regenerating liver vasculature

Author(s): Mahak Singhal, Xiaoting Liu, Donato Inverso, Kai Jiang, Jianing Dai, Hao He, Susanne Bartels, Weiping Li, Ashik Ahmed Abdul Pari, Nicolas Gengenbacher, Eva Besemfelder, Lijian Hui, Hellmut G. Augustin, Junhao Hu
Published in: Journal of Experimental Medicine, Issue 215/10, 2018, Page(s) 2497-2508, ISSN 0022-1007
Publisher: Rockefeller University Press
DOI: 10.1084/jem.20180008

Tumor Cell–Derived Angiopoietin-2 Promotes Metastasis in Melanoma

Author(s): Ashik Ahmed Abdul Pari, Mahak Singhal, Corinne Hübers, Carolin Mogler, Benjamin Schieb, Anja Gampp, Nicolas Gengenbacher, Louise E. Reynolds, Dorothee Terhardt, Cyrill Géraud, Jochen Utikal, Markus Thomas, Sergij Goerdt, Kairbaan M. Hodivala-Dilke, Hellmut G. Augustin, Moritz Felcht
Published in: Cancer Research, Issue 80/12, 2020, Page(s) 2586-2598, ISSN 0008-5472
Publisher: American Association for Cancer Research
DOI: 10.1158/0008-5472.can-19-2660

Preclinical validation of a novel metastasis‐inhibiting Tie1 function‐blocking antibody

Author(s): Mahak Singhal, Nicolas Gengenbacher, Silvia La Porta, Stephanie Gehrs, Jingjing Shi, Miki Kamiyama, Diane M Bodenmiller, Anthony Fischl, Benjamin Schieb, Eva Besemfelder, Sudhakar Chintharlapalli, Hellmut G Augustin
Published in: EMBO Molecular Medicine, Issue 12/6, 2020, ISSN 1757-4676
Publisher: John Wiley & Sons Ltd.
DOI: 10.15252/emmm.201911164