Studying Secondary Nucleation for the Intensification of Continuous Crystallization

Información del proyecto

SNICC

Identificador del acuerdo de subvención: 788607

DOI

10.3030/788607

Proyecto cerrado

Fecha de la firma de la CE 30 Mayo 2018

Fecha de inicio 1 Julio 2018

Fecha de finalización 31 Marzo 2024

Financiado con arreglo a

• EXCELLENT SCIENCE - European Research Council (ERC)

Coste total

€ 2 500 000,00

Aportación de la UE

€ 2 500 000,00

Coordinado por

EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH
Switzerland

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Publicaciones

Peer reviewed articles (26)

Model-based design of pressure-driven product removal from stirred suspensions

Autores: Ramona Achermann, Viktoria Wiedmeyer, Mercedeh Sadat Hosseinalipour, Selin Güngör, Marco Mazzotti
Publicado en: Chemical Engineering Research and Design, Edición 174, 2021, Página(s) 57-70, ISSN 0263-8762
Editor: Institute of Chemical Engineers
DOI: 10.1016/j.cherd.2021.07.001

Secondary Nucleation by Interparticle Energies. II. Kinetics

Autores: Byeongho Ahn; Luca Bosetti; Marco Mazzotti
Publicado en: Crystal Growth & Design, 22 (22), Edición 22 (22), 2022, Página(s) 74–86, ISSN 1528-7483
Editor: American Chemical Society
DOI: 10.3929/ethz-b-000519706

On Solute Recovery and Productivity in Chiral Resolution through Solid-State Deracemization by Temperature Cycling

Autores: Hosseinalipour, Mercedeh Sadat; id_orcid0000-0001-5524-0050; Deck, Leif-Thore; id_orcid0000-0002-0955-6801; Mazzotti, Marco
Publicado en: Crystal Growth & Design, 24 (9), Edición 2024, 24, 9, 3925–3932, 2024, ISSN 1528-7483
Editor: American Chemical Society
DOI: 10.1021/acs.cgd.4c00233

Characterization of a small-scale crystallizer using CFD simulations and X-ray CT measurements

Autores: Achermann, Ramona; id_orcid0000-0001-7537-4531; Adams, Robert; Prasser, Horst-Michael; Mazzotti, Marco
Publicado en: Chemical Engineering Science, Edición 2022, 256, 2022, Página(s) 117697, ISSN 0009-2509
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.ces.2022.117697

Conceptual Validation of Stochastic and Deterministic Methods To Estimate Crystal Nucleation Rates

Autores: Marco Mazzotti; Leif-Thore Deck
Publicado en: Crystal Growth & Design, 23 (2), Edición 2023, 23, 2, 2023, Página(s) 899–914, ISSN 1528-7483
Editor: American Chemical Society
DOI: 10.3929/ethz-b-000594916

Comparative assessment and possible applications of three models of Taylor slug flows

Autores: Achermann, Ramona; Antunes Morgado, Nicolas; Corti, Andrea Lucas; Mazzotti, Marco
Publicado en: Computers & Chemical Engineering, Edición 2022, 161, 2022, Página(s) 107773, ISSN 0098-1354
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.compchemeng.2022.107773

Secondary Nucleation by Interparticle Energies. III. Nucleation Rate Model

Autores: Marco Mazzotti; Luca Bosetti; Byeongho Ahn
Publicado en: Crystal Growth & Design, 22 (22), Edición 22 (22), 2022, Página(s) 3625–3636, ISSN 1528-7483
Editor: American Chemical Society
DOI: 10.3929/ethz-b-000546500

HPLC method development for the quantification of a mixture of reacting species: The case of lactose

Autores: Trespi, Silvio; Mazzotti, Marco
Publicado en: Journal of Chromatography A, 1715, Edición 2024, 1715, 464553, 2024, ISSN 0021-9673
Editor: Elsevier BV
DOI: 10.1016/j.chroma.2023.464553

Solid-State Deracemization via Temperature Cycles in Continuous Operation: Model-Based Process Design

Autores: Marco Mazzotti; Brigitta Bodák
Publicado en: Crystal Growth & Design, Edición 2022, 22, 3, 2022, Página(s) 1846–1856, ISSN 1528-7483
Editor: American Chemical Society
DOI: 10.3929/ethz-b-000539219

Population balance modelling of magnesium hydroxide precipitation: Full validation on different reactor configurations

Autores: Antonello Raponi; Ramona Achermann; Salvatore Romano; Silvio Trespi; Marco Mazzotti; Andrea Cipollina; Antonio Buffo; Marco Vanni; Daniele Marchisio
Publicado en: Chemical Engineering Journal, 477, Edición 2023, 477, 146540, 2023, ISSN 1385-8947
Editor: Elsevier BV
DOI: 10.1016/j.cej.2023.146540

Process Performance and Operational Challenges in Continuous Crystallization: A Study of the Polymorphs of <scp>L</scp>-Glutamic Acid

Autores: Ramona Achermann; Andraž Košir; Brigitta Bodák; Luca Bosetti; Marco Mazzotti
Publicado en: Crystal Growth & Design, Edición 2023 (23), 2023, Página(s) 2485−2503, ISSN 1528-7483
Editor: American Chemical Society
DOI: 10.1021/acs.cgd.2c01424

Exact and Ubiquitous Condition for Solid-State Deracemization in Vitro and in Nature

Autores: Deck, Leif-Thore; id_orcid0000-0002-0955-6801; Hosseinalipour, Mercedeh Sadat; id_orcid0000-0001-5524-0050; Mazzotti, Marco
Publicado en: Journal of the American Chemical Society, 146 (6), Edición 2024, 146, 6, 3872–3882, 2024, ISSN 0002-7863
Editor: American Chemical Society
DOI: 10.1021/jacs.3c11332

Study of Secondary Nucleation by Attrition of Potassium Alum Crystals Suspended in Different Solvents

Autores: Luca Bosetti, Marco Mazzotti
Publicado en: Crystal Growth & Design, Edición 20/4, 2020, Página(s) 2570-2577, ISSN 1528-7483
Editor: American Chemical Society
DOI: 10.1021/acs.cgd.9b01700

Population Balance Modeling of Growth and Secondary Nucleation by Attrition and Ripening

Autores: Luca Bosetti, Marco Mazzotti
Publicado en: Crystal Growth & Design, Edición 20/1, 2019, Página(s) 307-319, ISSN 1528-7483
Editor: American Chemical Society
DOI: 10.1021/acs.cgd.9b01240

Statistical Analysis and Nucleation Parameter Estimation from Nucleation Experiments in Flowing Microdroplets

Autores: Elena Cândida dos Santos, Giovanni Maria Maggioni, Marco Mazzotti
Publicado en: Crystal Growth & Design, Edición 19/11, 2019, Página(s) 6159-6174, ISSN 1528-7483
Editor: American Chemical Society
DOI: 10.1021/acs.cgd.9b00562

Modeling of Mixing‐Precipitation Processes: Agglomeration

Autores: Pawel M. Orlewski, Marco Mazzotti
Publicado en: Chemical Engineering & Technology, 2020, ISSN 0930-7516
Editor: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/ceat.201900551

Tuning the Particle Sizes in Spherical Agglomeration

Autores: Pawel M. Orlewski, Byeongho Ahn, Marco Mazzotti
Publicado en: Crystal Growth & Design, Edición 18/10, 2018, Página(s) 6257-6265, ISSN 1528-7483
Editor: American Chemical Society
DOI: 10.1021/acs.cgd.8b01134

Online Monitoring of the Concentrations of Amorphous and Crystalline Mesoscopic Species Present in Solution

Autores: Marco Mazzotti; Michele Chen; Byeongho Ahn
Publicado en: Crystal Growth & Design 22 (22), Edición 22, 2022, Página(s) 5071−5080, ISSN 1528-7483
Editor: American Chemical Society
DOI: 10.3929/ethz-b-000560961

Kinetics and Thermodynamics of Lactose Mutarotation through Chromatography

Autores: Silvio Trespi; Marco Mazzotti
Publicado en: Industrial & Engineering Chemistry Research, 63 (12), Edición 2024, 63, 12, 5028–5038, 2024, ISSN 0888-5885
Editor: American Chemical Society
DOI: 10.1021/acs.iecr.3c04110

Secondary Nucleation by Interparticle Energies. I. Thermodynamics

Autores: Luca Bosetti; Byeongho Ahn; Marco Mazzotti
Publicado en: Crystal Growth & Design, 22 (1), Edición 22 (1), 2021, Página(s) 87–97, ISSN 1528-7483
Editor: American Chemical Society
DOI: 10.3929/ethz-b-000523208

General stability analysis of the steady states in the continuous mixed-suspension crystallizer

Autores: Leif-Thore Deck; Marco Mazzotti
Publicado en: Chemical Engineering Journal, 483, Edición 2024, 483, 148721, 2024, ISSN 1385-8947
Editor: Elsevier BV
DOI: 10.1016/j.cej.2024.148721

The Role of Operating Conditions in the Precipitation of Magnesium Hydroxide Hexagonal Platelets Using NaOH Solutions

Autores: Salvatore Romano; Silvio Trespi; Ramona Achermann; Giuseppe Battaglia; Antonello Raponi; Daniele Marchisio; Marco Mazzotti; Giorgio Micale; Andrea Cipollina
Publicado en: Crystal Growth & Design, 23 (9), Edición 2023, 23, 9, 6491–6505, 2023, ISSN 1528-7483
Editor: American Chemical Society
DOI: 10.1021/acs.cgd.3c00462

Crystallization-Induced Deracemization: Experiments and Modeling

Autores: Marco Mazzotti; Brigitta Bodák; Francesca Breveglieri
Publicado en: Crystal Growth & Design, Edición 2022, 22 (2), 2022, Página(s) 1427–1436, ISSN 1528-7483
Editor: American Chemical Society
DOI: 10.1021/acs.cgd.1c01374

Deracemization via Periodic and Non-periodic Temperature Cycles: Rationalization and Experimental Validation of a Simplified Process Design Approach.

Autores: Francesca Breveglieri; Brigitta Bodák; Marco Mazzotti
Publicado en: Organic Process Research & Development, Edición 2021, 25, 11, 2021, Página(s) 2551–2565, ISSN 1083-6160
Editor: American Chemical Society
DOI: 10.3929/ethz-b-000518898

Accounting for the Presence of Molecular Clusters in Modeling and Interpreting Nucleation and Growth

Autores: Marco Mazzotti; Luca Bosetti; Byeongho Ahn
Publicado en: Crystal Growth & Design, 22 (1), Edición 22 (1), 2022, Página(s) 661–672, ISSN 1528-7483
Editor: American Chemical Society
DOI: 10.3929/ethz-b-000519719

On the model-based design and comparison of crystallization-based deracemization techniques

Autores: Brigitta Bodák; Francesca Breveglieri; Marco Mazzotti
Publicado en: Chemical Engineering Science, Edición 2022, 2022, Página(s) 117595, ISSN 0009-2509
Editor: Pergamon Press Ltd.
DOI: 10.3929/ethz-b-000541843

Thesis and dissertations (5)

Modeling of crystallization-based deracemization processes

Autores: Brigitta Bodak
Publicado en: 2022
Editor: ETH Zürich
DOI: 10.3929/ethz-b-000543520

Deracemization via batch temperature cycles - Combining racemization and crystallization for chiral resolution

Autores: Breveglieri, Francesca
Publicado en: Edición 5, 2021
Editor: ETH Zürich
DOI: 10.3929/ethz-b-000528254

Characterizing Mesoscopic Species Present in Solution and Modeling Their Roles in Crystallization Processes

Autores: Ahn, Byeongho; id_orcid0000-0002-4405-5041
Publicado en: Edición 1, 2022
Editor: ETH Zürich
DOI: 10.3929/ethz-b-000574827

Design, Operational Challenges and Opportunities for the Intensification of Continuous Crystallization

Autores: Ramona Achermann
Publicado en: 2023
Editor: ETH Zürich
DOI: 10.3929/ethz-b-000606968

Mechanisms and models of secondary nucleation

Autores: Luca Bosetti
Publicado en: 2021
Editor: ETH Zürich
DOI: 10.3929/ethz-b-000528059