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Remote control healing: Next generation mechano-nano-therapeutics

Deliverables

Data Management Plan

Participation in the Open Research Data Pilot

Publications

Short-Term Evaluation of Cellular Fate in an Ovine Bone Formation Model

Author(s): Hareklea Markides, Nicola C. Foster, Jane S. McLaren, Timothy Hopkins, Cameron Black, Richard O. C. Oreffo, Brigitte E. Scammell, Iria Echevarria, Lisa J. White, Alicia J. El Haj
Published in: Cells, 10/7, 2021, Page(s) 1776, ISSN 2073-4409
Publisher: MDPI
DOI: 10.3390/cells10071776

Parallelized Manipulation of Adherent Living Cells by Magnetic Nanoparticles-Mediated Forces

Author(s): Maud Bongaerts, Koceila Aizel, Emilie Secret, Audric Jan, Tasmin Nahar, Fabian Raudzus, Sebastian Neumann, Neil Telling, Rolf Heumann, Jean-Michel Siaugue, Christine Ménager, Jérôme Fresnais, Catherine Villard, Alicia El Haj, Jacob Piehler, Monte A. Gates, Mathieu Coppey
Published in: International Journal of Molecular Sciences, 21/18, 2020, Page(s) 6560, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21186560

The Grand Challenges of Medical Technology

Author(s): Alicia J. El Haj
Published in: Frontiers in Medical Technology, 2, 2020, ISSN 2673-3129
Publisher: Frontiers
DOI: 10.3389/fmedt.2020.00001

Wnt-modified materials mediate asymmetric stem cell division to direct human osteogenic tissue formation for bone repair

Author(s): Yoshihisa Okuchi, Joshua Reeves, Soon Seng Ng, Daniel H. Doro, Sergi Junyent, Karen J. Liu, Alicia J. El Haj, Shukry J. Habib
Published in: Nature Materials, 20/1, 2021, Page(s) 108-118, ISSN 1476-1122
Publisher: Nature Publishing Group
DOI: 10.1038/s41563-020-0786-5

Regenerative medicine meets mathematical modelling: developing symbiotic relationships

Author(s): S. L. Waters, L. J. Schumacher, A. J. El Haj
Published in: npj Regenerative Medicine, 6/1, 2021, ISSN 2057-3995
Publisher: Nature publishing Journals
DOI: 10.1038/s41536-021-00134-2

Regenerative Medicine: “Are We There Yet?”

Author(s): Alicia J. El Haj
Published in: Tissue Engineering Part A, 25/15-16, 2019, Page(s) 1067-1071, ISSN 1937-3341
Publisher: Mary Ann Liebert Inc.
DOI: 10.1089/ten.tea.2019.0134

Ex vivo MRI cell tracking of autologous mesenchymal stromal cells in an ovine osteochondral defect model

Author(s): Hareklea Markides, Karin J. Newell, Heike Rudorf, Lia Blokpoel Ferreras, James E. Dixon, Robert H. Morris, Martin Graves, Joshua Kaggie, Frances Henson, Alicia J. El Haj
Published in: Stem Cell Research & Therapy, 10/1, 2019, Page(s) all, ISSN 1757-6512
Publisher: BioMed Central
DOI: 10.1186/s13287-018-1123-7

Ultra Short Echo Time MRI of Iron-Labelled Mesenchymal Stem Cells in an Ovine Osteochondral Defect Model

Author(s): Joshua D. Kaggie, Hareklea Markides, Martin J. Graves, James MacKay, Gavin Houston, Alicia El Haj, Fiona Gilbert, Frances Henson
Published in: Scientific Reports, 10/1, 2020, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-020-64423-4

Experimental and mathematical modelling of magnetically labelled mesenchymal stromal cell delivery

Author(s): E. F. Yeo, H. Markides, A. T. Schade, A. J. Studd, J. M. Oliver, S. L. Waters, A. J. El Haj
Published in: Journal of The Royal Society Interface, 18/175, 2021, ISSN 1742-5662
Publisher: Royal society
DOI: 10.1098/rsif.2020.0558

Magnetic Mechanoactivation of Wnt Signaling Augments Dopaminergic Differentiation of Neuronal Cells

Author(s): Michael Rotherham, Tasmin Nahar, Timothy Goodman, Neil Telling, Monte Gates, Alicia El Haj
Published in: Advanced Biosystems, 3/9, 2019, Page(s) 1900091, ISSN 2366-7478
Publisher: WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
DOI: 10.1002/adbi.201900091

Magnetic biomaterials and nano-instructive tools as mediators of tendon mechanotransduction

Author(s): Ana M. Matos, Ana I. Gonçalves, Alicia J. El Haj, Manuela E. Gomes
Published in: Nanoscale Advances, 2/1, 2020, Page(s) 140-148, ISSN 2516-0230
Publisher: Royal Society of Chemistry
DOI: 10.1039/c9na00615j

Remote triggering of TGF-β/Smad2/3 signaling in human adipose stem cells laden on magnetic scaffolds synergistically promotes tenogenic commitment

Author(s): Ana M. Matos, Ana I. Gonçalves, Márcia T. Rodrigues, Margarida S. Miranda, Alicia J. El Haj, Rui L. Reis, Manuela E. Gomes
Published in: Acta Biomaterialia, 113, 2020, Page(s) 488-500, ISSN 1742-7061
Publisher: Elsevier BV
DOI: 10.1016/j.actbio.2020.07.009