Eukaryotic DNA replication: a single-molecule approach to the study of yeast replication on chromatin

Project Information

REPLICHROMA

Grant agreement ID: 789267

DOI

10.3030/789267

Project closed

EC signature date 26 July 2018

Start date 1 September 2018

End date 31 August 2023

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 388 100,00

EU contribution

€ 2 388 100,00

Coordinated by

TECHNISCHE UNIVERSITEIT DELFT
Netherlands

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (9)

CAF-1 deposits newly synthesized histones during DNA replication using distinct mechanisms on the leading and lagging strands

Author(s): Clément Rouillon; Bruna V Eckhardt; Leonie Kollenstart; Fabian Gruss; Alexander E E Verkennis; Inge Rondeel; Peter H L Krijger; Giulia Ricci; Alva Biran; Theo van Laar; Charlotte M Delvaux de Fenffe; Georgiana Luppens; Pascal Albanese; Koichi Sato; Richard A Scheltema; Wouter de Laat; Puck Knipscheer; Nynke H Dekker; Anja Groth; Francesca Mattiroli
Published in: Nucleic acids research, 2023, ISSN 0305-1048
Publisher: Oxford University Press
DOI: 10.1093/nar/gkad171

A Biophysics Toolbox for Reliable Data Acquisition and Processing in Integrated Force–Confocal Fluorescence Microscopy

Author(s): Zhaowei Liu, Edo van Veen, Humberto Sánchez, Belén Solano, Francisco J. Palmero Moya, Kaley A. McCluskey, Daniel Ramírez Montero, Theo van Laar, and Nynke H. Dekker
Published in: ACS Photonics, 2024, ISSN 2330-4022
Publisher: American Chemical Society
DOI: 10.1021/acsphotonics.3c01739

De novo fabrication of custom-sequence plasmids for the synthesis of long DNA constructs with extrahelical features

Author(s): Daniel Ramírez Montero, Zhaowei Liu, Nynke H. Dekker
Published in: Biophysical Journal, 2023, ISSN 0006-3495
Publisher: Biophysical Society
DOI: 10.1016/j.bpj.2023.11.008

DNA origins retain mobile licensing proteins

Author(s): Humberto Sánchez, Kaley McCluskey, Theo van Laar, Edo van Veen, Filip M. Asscher, Belén Solano, John F.X. Diffley and Nynke H. Dekker
Published in: Nature Communications, Issue 12, 2021, Page(s) 1908, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-22216-x

Nucleotide binding halts diffusion of the eukaryotic replicative helicase during activation

Author(s): Daniel Ramírez Montero; Humberto Sánchez; Edo van Veen; Theo van Laar; Belén Solano; John F. X. Diffley; Nynke H. Dekker
Published in: Nature Communications, 2023, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1101/2022.12.23.521684

A chromatinized origin reduces the mobility of ORC and MCM through interactions and spatial constraint

Author(s): Humberto Sánchez; Zhaowei Liu; Edo van Veen; Theo van Laar; John F. X. Diffley; Nynke H. Dekker
Published in: Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023), 2023, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1101/2023.05.18.541303

Global correction of optical distortions in multicolor single-molecule microscopy using Zernike polynomial gradients

Author(s): Kaley McCluskey; Edo van Veen; Jelmer Cnossen; Wouter Wesselink; Filip M. Asscher; Carlas Smith; Nynke H. Dekker
Published in: Optics Express, 2021, Page(s) 42251-42264, ISSN 1094-4087
Publisher: Optical Society of America
DOI: 10.1364/oe.445230

Three-dimensional localization microscopy with increased axial precision through TIRF angle modulation

Author(s): Daniel Fan; Jelmer Cnossen; Shih-Te Hung; Dimitri Kromm; Nynke H. Dekker; Gerard J. Verbiest; Carlas S. Smith
Published in: Optics Communications, 2023, Page(s) 129548, ISSN 0030-4018
Publisher: Elsevier BV
DOI: 10.1016/j.optcom.2023.129548

Principles and best practices of optimizing a micromirror-based multicolor TIRF microscopy system

Author(s): Kaley McCluskey; Nynke H. Dekker
Published in: Optics Communications, 2023, Page(s) 129474, ISSN 0030-4018
Publisher: Elsevier BV
DOI: 10.1101/2023.03.27.534330

Non-peer reviewed articles (1)

Physics meets biology: The joining of two forces to further our understanding of cellular function

Author(s): Michelle D. Wang, Mario Nicodemi, Nynke H. Dekker, Thomas Gregor, David Holcman, Antoine M. van Oijen, and Suliana Manley,
Published in: Molecular Cell, 2021, Page(s) 3033-3037, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2021.07.009