Objective
To properly function in daily life we need to interact with our surrounding world. How do these interactions forge our sensory cortices? And how does our visual cortex adapt in order to function in an altered environment? The proposed study combines functional magnetic resonance imaging (fMRI) and novel analysis of ecological real-life events with sensory-motor training in order to tackle these questions in both healthy and brain damaged individuals. We will use a specially designed virtual-reality-based prism-adaptation device (VR-PA) that creates a lateral shift in the user’s sensory experience, to probe experience-dependent changes in visual cortex functional connectivity. The VR-PA device will be used for rehabilitation of stroke patients suffering from an inability to attend stimuli in the left side of space (hemispatial neglect). We will explore the neuronal basis of this perceptual rehabilitation using functional connectivity methods in hemispatial neglect patients and in neurologically intact participants. We will use novel fMRI analyses to study how the severity of the perceptual impairment in neglect patients before treatment is reflected in altered pattern of intra-hemispheric connectivity in the primary visual cortex and in its connectivity with parietal areas. We will test whether exposure to VR-PA in healthy controls would result in a temporary imbalanced connectivity pattern, mimicking the patients’ condition. Conversely, in patients, VR-PA training, ameliorating perceptual deficits, would make connectivity patterns more similar to those of an intact brain. Multiple behavioural and physiological measures will be acquired during the training to identify key behavioural triggers of cortical plasticity. Combining the researcher's expertise in functional connectivity and the host specialization in multisensory-motor plasticity would create a platform for novel discoveries in the field of training-induced plasticity and its translational applications.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences clinical medicine physiotherapy
- medical and health sciences basic medicine neurology stroke
- engineering and technology medical engineering diagnostic imaging magnetic resonance imaging
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
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H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-IF-EF-SE - Society and Enterprise panel
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-IF-2017
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
1011 Lausanne
Switzerland
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.