Objective Plant dry matter, so-called lignocellulosic biomass, is the largest renewable biomass feedstock on Earth. Europe has over 14 mill tons of sugar residuals from biorefineries, which could be converted to profitable products and contribute to a sustainable bioeconomy. Unfortunately, existing biorefineries struggle with technical issues and low profitability due to the lack of adequate fermentation processes. Therefore, these sugars are either incinerated to generate energy or at best converted to ethanol (€0.6 /kg) but not to higher value chemicals.Current concepts that aim to establish fermentation processes to convert residual sugar streams to high value products face challenges including inefficient sugar utilization by microorganisms and inhibitors in the residual streams, leading to low productivity and yields.Our project aims to recover high value compounds from sugar residuals, and to turn fermentation processes converting these residual to antimicrobials cost effective. We will recover the high value sugar galactose (€40-200 /kg) from residual streams as part of their treatment process. By genome editing technique, we will design cell factories that consume the remaining residuals and produce nisin (€50-150 /kg), an industrially important commercial food/feed preservative. Additionally, we will develop an affordable, online feedback add-on system that will allow to intelligently change residual mixture during fermentation of these cell factories to optimize production online during the process. In a 150 L industrial bioreactor, we will demonstrate that our add-on invention iFermenter- increases the yields of nisin by over 2 fold- increases the pediocin production by over 50% compared to what is possible today,- and reduce at least 20% in CO2 footprint with this process compared to existing solutions.Thus, iFermenter will render production of high value products with residual sugar stream highly efficient and cost-effective contributing to circular economy. Fields of science engineering and technologyenvironmental biotechnologybioremediationbioreactorsmedical and health sciencesmedical biotechnologygenetic engineeringgene therapysocial scienceseconomics and businesseconomicssustainable economyagricultural sciencesagricultural biotechnologybiomassengineering and technologyindustrial biotechnologybioprocessing technologiesfermentation Programme(s) H2020-EU.3.2. - SOCIETAL CHALLENGES - Food security, sustainable agriculture and forestry, marine, maritime and inland water research, and the bioeconomy Main Programme H2020-EU.3.2.6.1. - Sustainable and competitive bio-based industries and supporting the development of a European bio-economy Topic(s) BBI.2017.R4 - Proteins and other bioactive ingredients from side streams and residues Call for proposal H2020-BBI-JTI-2017 See other projects for this call Funding Scheme RIA - Research and Innovation action Coordinator NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU Net EU contribution € 995 025,25 Address Hogskoleringen 1 7491 Trondheim Norway See on map Region Norge Trøndelag Trøndelag Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 350 874,75 Participants (11) Sort alphabetically Sort by Net EU contribution Expand all Collapse all UNIVERSITAET ULM Germany Net EU contribution € 438 000,00 Address Helmholtzstrasse 16 89081 Ulm See on map Region Baden-Württemberg Tübingen Ulm, Stadtkreis Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 42 890,00 UNIVERSITAT DES SAARLANDES Germany Net EU contribution € 613 875,00 Address Campus 66123 Saarbrucken See on map Region Saarland Saarland Regionalverband Saarbrücken Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 134 123,75 TECHNISCHE UNIVERSITAET WIEN Austria Net EU contribution € 728 266,00 Address Karlsplatz 13 1040 Wien See on map Region Ostösterreich Wien Wien Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 227 390,25 BIO BASE EUROPE PILOT PLANT VZW Belgium Net EU contribution € 438 473,75 Address Rodenhuizekaai 1 9042 Desteldonk gent See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Vlaams Gewest Prov. Oost-Vlaanderen Arr. Gent Activity type Other Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 UNIVERSIDAD DE SANTIAGO DE COMPOSTELA Spain Net EU contribution € 179 390,00 Address Colexio de san xerome praza do obradoiro s/n 15782 Santiago de compostela See on map Region Noroeste Galicia A Coruña Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 NORGES MILJO-OG BIOVITENSKAPLIGE UNIVERSITET Norway Net EU contribution € 146 500,00 Address Universitetstunet 3 1433 As See on map Region Norge Oslo og Viken Viken Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 3 750,00 BORREGAARD AS Norway Net EU contribution € 0,00 Address Hjalmar wessels vei 6 1721 Sarpsborg See on map Region Norge Oslo og Viken Viken Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 80 945,00 GALACTIC SA Belgium Net EU contribution € 0,00 Address Place d'escanaffles 23 7760 Escanaffles See on map Region Région wallonne Prov. Hainaut Arr. Tournai-Mouscron Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 MYBIOTECH GMBH Germany Net EU contribution € 128 025,00 Address Industriestrasse 1b 66802 Uberherrn See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Saarland Saarland Saarlouis Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 178 837,50 INFORS AG Switzerland Net EU contribution € 79 875,00 Address Rittergasse 27 4103 Bottmingen See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Schweiz/Suisse/Svizzera Nordwestschweiz Basel-Landschaft Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 286 762,50 DANMARKS TEKNISKE UNIVERSITET Denmark Net EU contribution € 250 395,00 Address Anker engelunds vej 101 2800 Kongens lyngby See on map Region Danmark Hovedstaden Københavns omegn Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 17 496,25
