Objective
Interspecific hybridization and genome doubling (allopolyploidy) are key factors in plant adaptation and speciation. These intriguing genomic processes cause extensive structural rearrangements and reprogramming of functional regulatory pathways inherited from parental species. Furthermore, hybrid species have shown broad phenotypic diversity. However, mechanisms responsible for genome stabilization after allopolyploidy remain poorly understood.
The aim of my project is to provide an interdisciplinary overview of the effects of polyploidy on structural and functional dynamics in a major crop, oilseed rape (Brassica napus). This polyploid species is an excellent system to unravel the long-term and immediate evolutionary effects of ancient and recent polyploid events. In my project, I will use a novel approach that combines (epi)genomics and transcriptomics in phenotypically contrasting polyploids to investigate the role of structural and (epi)genetic regulation in genome stabilization. This work includes, amongst others, the transfer of knowledge to the host lab of cutting-edge molecular and in silico DNA methylation analysis methods. More specifically, I will determine the effects of structural and functional dynamics on B. napus (1) meiotic behavior and fertility, (2) gene expression and (3) glucosinolate content. My findings will open new avenues for using standing variation to modify and ultimately enhance agronomic traits.
I have become a recognized evolutionary biologist working at the interface of ecology, genomics and molecular biology. From the expertise of the host lab and availability of technical platforms in situ, I will not only get acquainted with cytogenetics and metabolomics, but will increase my expertise in comparative genomics and in high throughput genotyping analyses. I will also extend my network towards the private sector and be integrated into a well-established European community, positioning me on track to succeed academically in France.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
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H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-IF-EF-ST - Standard EF
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-IF-2017
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
75007 PARIS CEDEX 07
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.