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Molecular and functional evolution of human CD8+ T cell repertoires

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Publications

Harnessing the Power of T Cells: The Promising Hope for a Universal Influenza Vaccine

Author(s): E. Clemens, Carolien van de Sandt, Sook Wong, Linda Wakim, Sophie Valkenburg
Published in: Vaccines, Issue 6/2, 2018, Page(s) 18, ISSN 2076-393X
DOI: 10.3390/vaccines6020018

Back to the Future: Lessons Learned From the 1918 Influenza Pandemic

Author(s): Kirsty R. Short, Katherine Kedzierska, Carolien E. van de Sandt
Published in: Frontiers in Cellular and Infection Microbiology, Issue 8, 2018, ISSN 2235-2988
DOI: 10.3389/fcimb.2018.00343

Breadth of concomitant immune responses prior to patient recovery: a case report of non-severe COVID-19

Author(s): Irani Thevarajan, Thi H. O. Nguyen, Marios Koutsakos, Julian Druce, Leon Caly, Carolien E. van de Sandt, Xiaoxiao Jia, Suellen Nicholson, Mike Catton, Benjamin Cowie, Steven Y. C. Tong, Sharon R. Lewin, Katherine Kedzierska
Published in: Nature Medicine, 2020, ISSN 1078-8956
DOI: 10.1038/s41591-020-0819-2

Challenging immunodominance of influenza-specific CD8+ T cell responses restricted by the risk-associated HLA-A*68:01 allomorph

Author(s): C. E. van de Sandt, E. B. Clemens, E. J. Grant, L. C. Rowntree, S. Sant, H. Halim, J. Crowe, A. C. Cheng, T. C. Kotsimbos, M. Richards, A. Miller, S. Y. C. Tong, J. Rossjohn, T. H. O. Nguyen, S. Gras, W. Chen, K. Kedzierska
Published in: Nature Communications, Issue 10/1, 2019, ISSN 2041-1723
DOI: 10.1038/s41467-019-13346-4

Human Mucosal-Associated Invariant T Cells in Older Individuals Display Expanded TCRαβ Clonotypes with Potent Antimicrobial Responses

Author(s): Liyen Loh, Nicholas A. Gherardin, Sneha Sant, Ludivine Grzelak, Jeremy Chase Crawford, Nicola L. Bird, Hui-Fern Koay, Carolien E. van de Sandt, Marcela L. Moreira, Martha Lappas, E. Kaitlynn Allen, Jane Crowe, Thomas Loudovaris, Katie L. Flanagan, Kylie M. Quinn, Jamie Rossjohn, Paul G. Thomas, Sidonia B. G. Eckle, James McCluskey, Dale I. Godfrey, Katherine Kedzierska
Published in: The Journal of Immunology, Issue 204/5, 2020, Page(s) 1119-1133, ISSN 0022-1767
DOI: 10.4049/jimmunol.1900774

Metabolic characteristics of CD8+ T cell subsets in young and aged individuals are not predictive of functionality

Author(s): Kylie M. Quinn, Tabinda Hussain, Felix Kraus, Luke E. Formosa, Wai K. Lam, Michael J. Dagley, Eleanor C. Saunders, Lisa M. Assmus, Erica Wynne-Jones, Liyen Loh, Carolien E. van de Sandt, Lucy Cooper, Kim L. Good-Jacobson, Katherine Kedzierska, Laura K. Mackay, Malcolm J. McConville, Georg Ramm, Michael T. Ryan, Nicole L. La Gruta
Published in: Nature Communications, Issue 11/1, 2020, ISSN 2041-1723
DOI: 10.1038/s41467-020-16633-7