Objective
A primary crop in Ireland, wheat is the most important cereal within the EU. Zymoseptoria tritici, the causal agent of septoria tritici blotch (STB) disease, continuously threatens Europe’s wheat crop causing loses of up to 50%, if left untreated. The absence of commercial varieties with adequate STB resistance means the sector is wholly dependent on fungicides to offset STB, with control costs >€1bn pa. This chemical dependency has driven the appearance of fungicide resistant strains of Z. tritici. In addition, EU legislation has removed several fungicides due to environmental concerns. In short, the European wheat sector has an unsustainable future unless greater effort is made to identify durable sources of resistance to STB. This is where new breeding methodologies (e.g. genomic selection, GS) can assist traditional breeding initiatives. GS is a form of marker assisted selection that simultaneously estimates all loci, haplotype or marker effects across the entire genome to calculate Genomic Estimated Breeding Values (GEBVs). GEBVs are then used to select individuals of interest for advancement in the breeding cycle. This proposal will apply a GS strategy to a unique population (>600) of wheat lines (DiverseMAGIC, NIAB), that are firstly phenotyped in the presence of natural field-borne STB inoculum. Taking advantage of NIAB resources (35K SNP data, exome capture, genetic maps), this action will combine genotype and field phenotype data so that relevant QTL associated with contrasting STB resistant profiles can be identified. In parallel, an in-house gene editing system will be employed to edit several gene sequences that have demonstrated to be STB responsive based on previously accumulated RNAseq data. Multi-disciplinary in nature, we envisage this proposal (plus secondment) will identify novel sources of resistance to STB disease that thereafter will be integrated into European wheat breeding programmes through existing networks with this project’s partners.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences medical biotechnology genetic engineering gene therapy
- natural sciences biological sciences genetics genomes
- agricultural sciences agriculture, forestry, and fisheries agriculture grains and oilseeds cereals
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
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H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-IF-EF-ST - Standard EF
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-IF-2017
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
R93 Carlow
Ireland
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.