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Triaxial Magnetic Fields for the Control of Bioactive Materials in Bone Engineering

Objective

Magnetic tissue engineering envisions the development of complex systems in which magnetic elements are exploited as remotely controlled multidimensional tools with potential for diagnostic and therapeutic actions. Such a magnetic material can be imagined as a fixed “station” that offers a long-living assistance to tissue engineering, providing thus a unique opportunity to adjust the material activity to the personal needs of the patient. In the development of biomaterials for bone repair one of the major concerns is to increase their integration and remodeling rate. The possibility of favoring bone tissue engineering applications by magnetic stimulation in patients with reduced endogenous potential is a key issue, in consideration of the progressive ageing of the population for which more effective and personalized regenerative therapies will be increasingly demanded in the incoming decades. The original main driving idea of this project is the use triaxial magnetic fields for the creation of a conceptually new type of bioactive materials able to be manipulated directly in situ. To date all studies with magnetic biomaterials have been carried out only in presence of uniaxial fields. The very novelty of this project is the enhanced magnetic susceptibility in three dimensions by applying a triaxial magnetic field to a magnetic particles suspension. In principle, with such a configuration it is possible to magnetically drive the self-assembly of the particles producing extraordinarily well-controlled structures at the microscale. This novel approach, involving the use of triaxial fields, is expected to culminate in a new generation of materials with a specific, continuous and reloaded control from an external supervising center and new characteristics in tissue engineering, such as multiple uses, possibly multipurpose delivery and, furthermore, improved mechanical properties since magnetorheology under triaxial fields is still completely unexplored field of research.

Fields of science (EuroSciVoc)

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Programme(s)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MSCA-IF-EF-ST - Standard EF

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) H2020-MSCA-IF-2017

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Coordinator

UNIVERSIDAD DE GRANADA
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 170 121,60
Address
CUESTA DEL HOSPICIO SN
18071 GRANADA
Spain

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Region
Sur Andalucía Granada
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 170 121,60
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