Objective X-ray computed tomography (CT) is a widespread medical imaging modality with 85 million examinations performed in 2012 in the US alone, but there is a need for improving instrumentation to minimize the potential health risks due to radiation dose. Although the benefits of CT imaging greatly outweigh the risks, the dose must be minimized, especially for children. Using other modalities may not be an option since ultrasonography lacks sufficient diagnostic quality and MRI is time-consuming, expensive and may require sedation of small children.At KTH Royal Institute of Technology, a photon-counting silicon-strip detector that promises better image quality and lower dose than today’s CT detectors has been developed. In the proposed project, this detector will be used to develop a new CT technique for imaging children: low-dose photon counting CT. To this end, a reconstruction algorithm for low-dose imaging will be developed and tested by imaging phantoms. The imaging performance will be compared to current state-of-the art CT and x-ray radiography systems.General Electric (GE) is a market-leading CT vendor with the experience necessary to turn this idea into a product used in the clinic. The applicant will therefore carry out the 12-month outgoing phase at GE Global Research Center, Niskayuna, in close collaboration with GE Healthcare, Milwaukee. During the return phase, the applicant will use the experience gained from GE Global Research for continuing the research into photon-counting CT at KTH. In this way, KTH gains access to the expertise of GE on image reconstruction while GE gets an opportunity to evaluate the feasibility of integrating the photon-counting CT detector into a commercial CT scanner.A successful outcome can have a large impact on children’s health by allowing projection radiography to be replaced by CT and by decreasing the CT radiation exposure by at least 50%, enabling new examinations that are not done today due to radiation safety concerns. Fields of science engineering and technologymedical engineeringdiagnostic imagingx-ray radiographyengineering and technologymedical engineeringdiagnostic imagingcomputed tomographynatural sciencesphysical sciencestheoretical physicsparticle physicsphotons Programme(s) H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility Topic(s) MSCA-IF-2017 - Individual Fellowships Call for proposal H2020-MSCA-IF-2017 See other projects for this call Funding Scheme MSCA-IF-GF - Global Fellowships Coordinator KUNGLIGA TEKNISKA HOEGSKOLAN Net EU contribution € 166 993,80 Address BRINELLVAGEN 8 100 44 Stockholm Sweden See on map Region Östra Sverige Stockholm Stockholms län Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 166 993,80 Partners (1) Sort alphabetically Sort by Net EU contribution Expand all Collapse all Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. GENERAL ELECTRIC COMPANY United States Net EU contribution € 0,00 Address 41 FARNSWORTH STREET 02210 BOSTON MA See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 80 065,20
