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Neural circuitry and health consequences of cognitive bias

Objective

Stress has long been a major concern among researchers interested in health and welfare. Most of their work has considered stress from either a biological or an environmental perspective, focusing on the activation of the physiological systems involved in the stress process or the role of stressful life events in specific diseases. While interesting, if we are to fully understand the effects of stress on health, we must also take into account a psychological perspective that considers an individual’s perception of stress. Indeed, a deep understanding of the neural circuitry underlying psychological stress and its physiological consequences is crucial to meaningfully explain inter-individual variations in vulneraibility to stress. In this way, my ongoing research has revealed some preliminary results which indicate ‒ for the first time ‒ that cognitive bias towards pessimistic judgments (i.e. some individuals consistently evaluate ambiguous stimuli as negative) may predict an individual’s susceptibility to the detrimental effects of chronic stress. These groundbreaking results shed light on a completely unexplored and highly promising avenue of research, based on the potential impact of evaluation biases regarding stress on an individual’s vulnerability to stress-associated diseases. In this framework, COGBIAS firstly aims to characterise the specific neural circuits underlying cognitive bias by which stress is perceived, processed, and transduced into a neuroendocrine response, using zebrafish (Danio rerio) as a model. Secondly, COGBIAS aims to unravel the role of subjective stress on resilience to stress-associated diseases. Hence, the multidisciplinary and unique perspective of this project, combining behavioural, neural, genetic, and physiological sciences, has the potential to reinforce the already European competitiveness in the area of stress-related health and management.

Keywords

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Programme(s)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MSCA-IF - Marie Skłodowska-Curie Individual Fellowships (IF)

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) H2020-MSCA-IF-2017

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Coordinator

FUNDACAO CALOUSTE GULBENKIAN
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 270 862,20
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 270 862,20

Partners (1)

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