International Cancer Research Fellowships - 2 | iCARE-2 | Projet | Résultats | H2020 | CORDIS

CORDIS fournit des liens vers les livrables publics et les publications des projets HORIZON.

Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .

Livrables

Link to Euraxess website for first call for proposals

Link to Euraxess website for first call for proposals to inform the Project Officer on publishing each call for proposals, by sending the link to the Euraxess website and a screen shot of the related call announcement. Month 1

Link to Euraxess website for second call for proposals

Link to Euraxess website for second call for proposals to inform the Project Officer on publishing each call for proposals, by sending the link to the Euraxess website and a screen shot of the related call announcement. Month 13.

Report for Second call for proposals on dissemination activities

Report for Second call for proposals on dissemination activities; Month 24 (containing at least the following information): Dates of Call Publication and places where it was published (Supporting documents are required as images, screen shots, photos from events); Flyers, brochures, or other information produced; Presentations, conferences and meetings or other events; Published articles in the press (please list and attach only main articles); Any other means of advertising the programme.

Report for First call for proposals on dissemination activities

Report for First call for proposals on dissemination activities; Month 12 (containing at least the following information): - Dates of Call Publication and places where it was published (Supporting documents are required as images, screen shots, photos from events); - Flyers, brochures, or other information produced; - Presentations, conferences and meetings or other events; - Published articles in the press (list and attach only main articles); - Any other means of advertising the programme.

Publications

A Novel Analysis Method for Evaluating the Interplay of Oxygen and Ionizing Radiation at the Gene Level.

Auteurs: Jeannette Jansen; Jeannette Jansen; Patricia Vieten; Patricia Vieten; Francesca Pagliari; Rachel Hanley; Rachel Hanley; Maria Grazia Marafioti; Luca Tirinato; Luca Tirinato; Joao Seco; Joao Seco
Publié dans: Frontiers in Genetics, 2021, ISSN 1664-8021
Éditeur: Frontiers Media
DOI: 10.3389/fgene.2021.597635

PillarX: A Microfluidic Device to Profile Circulating Tumor Cell Clusters Based on Geometry, Deformability, and Epithelial State

Auteurs: Brenda J. Green, Margherita Marazzini, Ben Hershey, Amir Fardin, Qingsen Li, Zongjie Wang, Giovanni Giangreco, Federica Pisati, Stefano Marchesi, Andrea Disanza, Emanuela Frittoli, Emanuele Martini, Serena Magni, Galina V. Beznoussenko, Claudio Vernieri, Riccardo Lobefaro, Dario Parazzoli, Paolo Maiuri, Kristina Havas, Mahmoud Labib, Sara Sigismund, Pier Paolo Di Fiore, Rosalind H. Gunby, Shana O.
Publié dans: Small ., 2022, ISSN 1613-6829
Éditeur: Wiley-VCH GmbH, Weinheim
DOI: 10.1002/smll.202106097

IL-1R8 silencing improves the anti-tumor function of freshly isolated human NK cells

Auteurs: Nadine Landolina; Francesca Romana Mariotti; Tiziano Ingegnere; Claudia Alicata; Biancamaria Ricci; Andrea Pelosi; Irene Veneziani; Bruno Giuseppe Azzarone; Cecilia Garlanda; Alberto Mantovani; Lorenzo Moretta; Enrico Maggi
Publié dans: Journal for ImmunoTherapy of Cancer, Numéro 11, 2022, ISSN 2051-1426
Éditeur: BMJ
DOI: 10.1136/jitc-2021-003858

Integrated Genomics Identifies miR-181/TFAM Pathway as a Critical Driver of Drug Resistance in Melanoma

Auteurs: Anna Barbato , Antonella Iuliano , Mariagrazia Volpe , Romina D'Alterio , Simona Brillante , Filomena Massa , Rossella De Cegli , Sabrina Carrella , Massimiliano Salati , Annapina Russo3, Giulia Russo , Sara Riccardo , Davide Cacchiarelli , Mariaelena Capone , Gabriele Madonna , Paolo A Ascierto , Brunella Franco , Alessia Indrieri , Pietro Carotenuto
Publié dans: Int J Mol Sci, 2021, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22041801

Emerging Strategies for Immunotherapy of Solid Tumors Using Lipid-Based Nanoparticles

Auteurs: Soraia Fernandes, Marco Cassani, Francesca Cavalieri, Giancarlo Forte, Frank Caruso
Publié dans: Advanced Science, 2023, ISSN 2198-3844
Éditeur: Wiley
DOI: 10.1002/advs.202305769

Interaction Between MDSC and NK Cells in Solid and Hematological Malignancies: Impact on HSCT.

Auteurs: Nicola Tumino; Anna Laura Di Pace; Francesca Besi; Linda Quatrini; Paola Vacca; Lorenzo Moretta
Publié dans: Frontiers in Immunology, Numéro 49, 2021, ISSN 1664-3224
Éditeur: Frontiers Media
DOI: 10.3389/fimmu.2021.638841

Radio-resistance of hypoxic tumors: exploring the effects of oxygen and X-ray radiation on non-small lung cancer cell lines

Auteurs: Rachel Hanley; Francesca Pagliari; Daniel Garcia-Calderón; Joana Fernandes Guerreiro; Géraldine Genard; Jeannette Jansen; Clelia Nisticò; Maria Grazia Marafioti; Luca Tirinato; Joao Seco
Publié dans: Radiation Oncology, Numéro 21, 2023, ISSN 0360-3016
Éditeur: Elsevier BV
DOI: 10.1186/s13014-023-02275-8

Generation and maturation of human iPSC-derived 3D organotypic cardiac microtissues in long-term culture

Auteurs: Ece Ergir, Jorge Oliver-De La Cruz, Soraia Fernandes, Marco Cassani, Francesco Niro, Daniel Pereira-Sousa, Jan Vrbský, Vladimír Vinarský, Ana Rubina Perestrelo, Doriana Debellis, Natália Vadovičová, Stjepan Uldrijan, Francesca Cavalieri, Stefania Pagliari, Heinz Redl, Peter Ertl & Giancarlo Forte
Publié dans: Scientific Reports, 2022, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-022-22225-w

The Role of the Microenvironment and Cell Adhesion Molecules in Chronic Lymphocytic Leukemia

Auteurs: Marina Cerreto,Robin Foà andmAlessandro Natoni
Publié dans: Cancers, 2023, ISSN 2072-6694
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers15215160

Diphenylene Iodonium Is a Noncovalent MAO Inhibitor: A Biochemical and Structural Analysis

Auteurs: Luca G. Iacovino, Dr. Joana Reis, Prof. Antonello Mai, Prof. Claudia Binda, Prof. Andrea Mattevi
Publié dans: ChemMedChem, 2020, ISSN 1860-7187
Éditeur: Wiley-VCH
DOI: 10.1002/cmdc.202000264

Group 1 ILCs regulate T cell–mediated liver immunopathology by controlling local IL-2 availability

Auteurs: Valeria Fumagalli , Valentina Venzin , Pietro Di Lucia , Federica Moalli , Xenia Ficht , Gioia Ambrosi , Leonardo Giustini 1, Francesco Andreata , Marta Grillo , Diletta Magini , Micol Ravà , Christin Friedrich , Jason D Fontenot , Philippe Bousso , Sarah A Gilmore , Shahzada Khan , Manuel Baca , Eric Vivier, Georg Gasteiger , Mirela Kuka , Luca G Guidotti , Matteo Iannacone
Publié dans: Sci Immunol ., 2022, ISSN 2470-9468
Éditeur: American Association for the Advancement of Science
DOI: 10.1126/sciimmunol.abi6112

The Immune Checkpoint PD-1 in Natural Killer Cells: Expression, Function and Targeting in Tumour Immunotherapy

Auteurs: Linda Quatrini, Francesca Romana Mariotti, Enrico Munari, Nicola Tumino, Paola Vacca, Lorenzo Moretta
Publié dans: Cancers, Numéro 12, 2024, Page(s) 3285, ISSN 2072-6694
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12113285

Cell-Membrane-Coated and Cell-Penetrating Peptide-Conjugated Trimagnetic Nanoparticles for Targeted Magnetic Hyperthermia of Prostate Cancer Cells

Auteurs: Valentin Nica; Attilio Marino; Carlotta Pucci; Özlem Şen; Melis Emanet; Daniele De Pasquale; Alessio Carmignani; Andrea Petretto; Martina Bartolucci; Simone Lauciello; Rosaria Brescia; Francesco de Boni; Mirko Prato; Sergio Marras; Filippo Drago; Mohaned Hammad; Doris Segets; Gianni Ciofani
Publié dans: ACS Appl. Mater. Interfaces, Numéro 1, 2023, ISSN 1944-8244
Éditeur: American Chemical Society
DOI: 10.1021/acsami.3c07248

Dynamic chromosomal interactions and control of heterochromatin positioning by Ki67

Auteurs: van Schaik, Tom; Manzo, Stefano G; Vouzas, Athanasios E; Liu, Ning Qing; Teunissen, Hans; de Wit, Elzo; Gilbert, David M; van Steensel, Bas
Publié dans: EMBO Rep, Numéro 32, 2022, ISSN 1469-221X
Éditeur: Nature Publishing Group
DOI: 10.1101/2021.10.20.465140

The Pervasive Role of the miR-181 Family in Development, Neurodegeneration, and Cancer

Auteurs: Alessia Indrieri ,Sabrina Carrella ,Pietro Carotenuto ,Sandro Banfi, Brunella Franco
Publié dans: International Journal of Molecular Sciences, 2020, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21062092

Human lung-cancer-cell radioresistance investigated through 2D network topology

Auteurs: Luca Tirinato; Valentina Onesto; Daniel Garcia-Calderon; Francesca Pagliari; Maria-Francesca Spadea; Joao Seco; Francesco Gentile
Publié dans: Scientific Reports, Numéro 15, 2022, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-022-17018-0

AATF/Che‐1 localizes to paraspeckles and suppresses R‐loops accumulation and interferon activation in Multiple Myeloma

Auteurs: Tiziana Bruno, Giacomo Corleone, Valeria Catena , Clelia Cortile , Francesca De Nicola, Francesca Fabretti, Svitlana Gumenyuk, Francesco Pisani, Andrea Mengarelli , Claudio Passananti, and Maurizio Fanciulli
Publié dans: EMBO J, 2022, ISSN 0261-4189
Éditeur: Nature Publishing Group
DOI: 10.15252/embj.2021109711

Glucocorticoids and the cytokines IL-12, IL-15, and IL-18 present in the tumor microenvironment induce PD-1 expression on human natural killer cells.

Auteurs: Linda Quatrini; Paola Vacca; Nicola Tumino; Francesca Besi; Anna Laura Di Pace; Francesca Scordamaglia; Stefania Martini; Enrico Munari; Maria Cristina Mingari; Sophie Ugolini; Lorenzo Moretta
Publié dans: Journal of Allergy and Clinical Immunology, Numéro 7, 2021, ISSN 0091-6749
Éditeur: Mosby Inc.
DOI: 10.1016/j.jaci.2020.04.044

Sialofucosylation Enables Platelet Binding to Myeloma Cells via P-Selectin and Suppresses NK Cell-Mediated Cytotoxicity

Auteurs: Alessandro Natoni; Marina Cerreto; Maria Stefania De Propris; Maria Teresa Petrucci; Francesca Fazio; Stefania Intoppa; Maria Laura Milani; Lucy Kirkham-McCarthy; Robert Henderson; Dawn Swan; Anna Guarini; Michael O’Dwyer; Robin Foà
Publié dans: Cancers, Numéro 1, 2023, ISSN 2072-6694
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers15072154

ROS and Lipid Droplet accumulation induced by high glucose exposure in healthy colon and Colorectal Cancer Stem Cells.

Auteurs: Luca Tirinato; Luca Tirinato; Luca Tirinato; Francesca Pagliari; Francesca Pagliari; Simone Di Franco; Elisa Sogne; Maria Grazia Marafioti; Jeanette Jansen; Jeanette Jansen; Andrea Falqui; Matilde Todaro; Patrizio Candeloro; Carlo Liberale; Joao Seco; Joao Seco; Giorgio Stassi; Enzo Di Fabrizio
Publié dans: Genes and Diseases, Numéro 1, 2020, ISSN 2352-3042
Éditeur: Beijing: Publishing services by Elsevier B.V. on behalf of KeAi Communications Co. Ltd.
DOI: 10.1016/j.gendis.2019.09.010

Toll-like receptor 8 agonists improve NK-cell function primarily targeting CD56<sup>bright</sup>CD16<sup>−</sup> subset

Auteurs: Irene Veneziani; Claudia Alicata; Andrea Pelosi; Nadine Landolina; Biancamaria Ricci; Valentina D'Oria; Anna Fagotti; Giovanni Scambia; Lorenzo Moretta; Enrico Maggi
Publié dans: Journal for ImmunoTherapy of Cancer, Numéro 1, 2022, ISSN 2051-1426
Éditeur: BMJ
DOI: 10.1136/jitc-2021-003385

Generation and Characterization of a Tumor Stromal Microenvironment and Analysis of Its Interplay with Breast Cancer Cells: An In Vitro Model to Study Breast Cancer-Associated Fibroblast Inactivation

Auteurs: Veronica Romano; Maria Rosaria Ruocco; Pietro Carotenuto; Anna Barbato; Alessandro Venuta; Vittoria Acampora; Sabrina De Lella; Elena Vigliar; Antonino Iaccarino; Giancarlo Troncone; Gaetano Calì; Luigi Insabato; Daniela Russo; Brunella Franco; Stefania Masone; Nunzio Velotti; Antonello Accurso; Tommaso Pellegrino; Giuseppe Fiume; Immacolata Belviso; Stefania Montagnani; Angelica Avagliano; Aless
Publié dans: International Journal of Molecular Sciences, Numéro 15, 2022, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23126875

miR-9 modulates and predicts the response to radiotherapy and EGFR inhibition in HNSCC.

Auteurs: Francesca Citron; Francesca Citron; Ilenia Segatto; Lorena Musco; Ilenia Pellarin; Gian Luca Rampioni Vinciguerra; Gian Luca Rampioni Vinciguerra; Giovanni Franchin; Giuseppe Fanetti; Francesco Miccichè; Vittorio Giacomarra; Valentina Lupato; Andrea Favero; Isabella Concina; Sanjana Srinivasan; Michele Avanzo; Isabella Castiglioni; Isabella Castiglioni; Luigi Barzan; Sandro Sulfaro; Gianluigi Pet
Publié dans: EMBO Molecular Medicine, Numéro 24, 2021, ISSN 1757-4676
Éditeur: John Wiley & Sons Ltd.
DOI: 10.15252/emmm.202012872

Polymorphonuclear myeloid-derived suppressor cells impair the anti-tumor efficacy of GD2.CAR T-cells in patients with neuroblastoma.

Auteurs: Nicola Tumino; Gerrit Weber; Francesca Besi; Francesca Del Bufalo; Valentina Bertaina; Paola Paci; Linda Quatrini; Laura Antonucci; Matilde Sinibaldi; Concetta Quintarelli; Enrico Maggi; Biagio De Angelis; Franco Locatelli; Franco Locatelli; Lorenzo Moretta; Paola Vacca; Ignazio Caruana
Publié dans: Journal of Hematology & Oncology, Numéro 28, 2021, ISSN 1756-8722
Éditeur: BioMed Central
DOI: 10.1186/s13045-021-01193-0

The Replication Stress Response on a Narrow Path Between Genomic Instability and Inflammation.

Auteurs: Hervé Técher; Philippe Pasero
Publié dans: Frontiers in Cell and Developmental Biology, Numéro 54, 2021, ISSN 2296-634X
Éditeur: Frontiers Media S.A
DOI: 10.3389/fcell.2021.702584

Micro-RNA in Cholangiocarcinoma: Implications for Diagnosis, Prognosis, and Therapy

Auteurs: Anna Barbato; Fabiola Piscopo; Massimiliano Salati; Luca Reggiani-Bonetti; Brunella Franco; Pietro Carotenuto
Publié dans: Journal of Molecular Pathology, Numéro 1, 2022, ISSN 2673-5261
Éditeur: MDPI AG, 2020
DOI: 10.3390/jmp3020009

Bone marrow vasculature advanced in vitro models for cancer and cardiovascular research

Auteurs: Marzia Campanile,Leonardo Bettinelli Camilla Cerutti Gaia Spinetti1
Publié dans: Front. Cardiovasc. Med, 2023, ISSN 2297-055X
Éditeur: Frontiers media
DOI: 10.3389/fcvm.2023.1261849

YAP signaling regulates the cellular uptake and therapeutic effect of nanoparticles

Auteurs: Marco Cassani; Soraia Fernandes; Jorge Oliver‐De La Cruz; Helena Durikova; Jan Vrbsky; Marek Patočka; Veronika Hegrova; Simon Klimovic; Jan Pribyl; Doriana Debellis; Petr Skladal; Francesca Cavalieri; Frank Caruso; Giancarlo Forte
Publié dans: Advanced Science, Numéro 33, 2023, ISSN 2198-3844
Éditeur: Wiley-VCH, 2014
DOI: 10.1101/2023.03.10.532035

Dissecting Clonal Hematopoiesis in Tissues of Patients with Classic Hodgkin Lymphoma

Auteurs: Alessandra Venanzi; Andrea Marra ; Gianluca Schiavoni; Sara G. Milner; Roberto Limongello; Alessia Santi; Valentina Pettirossi; Simona Ultimo; Luisa Tasselli ; Alessandra Pucciarini; Lorenza Falini ; Sofia Sciabolacci; Maria Paola Martelli ; Paolo Sportoletti; Stefano Ascani; Brunangelo Falini ; Enrico Tiacci
Publié dans: Blood Cancer Discov, 2021, ISSN 2643-3249
Éditeur: American Association for Cancer Research, Inc
DOI: 10.1158/2643-3230.bcd-20-0203

Microbiota-derived 3-IAA influences chemotherapy efficacy in pancreatic cancer

Auteurs: Joseph Tintelnot, Yang Xu, Till R. Lesker, Martin Schönlein, Leonie Konczalla, Anastasios D. Giannou, Penelope Pelczar, Dominik Kylies, Victor G. Puelles, Agata A. Bielecka, Manuela Peschka, Filippo Cortesi, Kristoffer Riecken, Maximilian Jung, Lena Amend, Tobias S. Bröring, Marija Trajkovic-Arsic, Jens T. Siveke, Thomas Renné, Danmei Zhang, Stefan Boeck, Till Strowig, Faik G. Uzunoglu, Cenap G
Publié dans: Nature, 2023, ISSN 1476-4687
Éditeur: Springer Nature
DOI: 10.1038/s41586-023-05728-y

Helper Innate Lymphoid Cells in Allogenic Hematopoietic Stem Cell Transplantation and Graft Versus Host Disease

Auteurs: Linda Quatrini; Nicola Tumino; Francesca Moretta; Francesca Besi; Paola Vacca; Lorenzo Moretta
Publié dans: Frontiers in Immunology, 2020, ISSN 1664-3224
Éditeur: Frontiers Media S.A
DOI: 10.3389/fimmu.2020.582098

The anti-inflammatory cytokine IL-37 improves the NK cell-mediated anti-tumor response

Auteurs: Nadine Landolina,Francesca Romana MariottiORCID Icon,Andrea Pelosi,Valentina D’Oria,Tiziano Ingegnere,Claudia Alicata, Paola vacca, Lorenzo Moretta, Enrico Maggi
Publié dans: OncoImmunology, 2023, ISSN 2162-402X
Éditeur: Taylor and Francis Online
DOI: 10.1080/2162402x.2023.2297504

Targeting the MITF/APAF-1 axis as salvage therapy for MAPK inhibitors in resistant melanoma

Auteurs: Pietro Carotenuto, Alessia Romano, Anna Barbato, Paola Quadrano, Simona Brillante, Mariagrazia Volpe, Luigi Ferrante, Roberta Tammaro, Manuela Morleo, Rossella De Cegli, Antonella Iuliano, Marialuisa Testa, Fabrizio Andreone, Gennaro Ciliberto, Eduardo Clery, Giancarlo Troncone, Giuseppe Palma, Claudio Arra, Antonio Barbieri, Mariaelena Capone, Gabriele Madonna, Paolo A. Ascierto, Luisa Lanfrancon
Publié dans: Cell Reports, Numéro 41, 2023, Page(s) 111601, ISSN 2211-1247
Éditeur: Cell Press
DOI: 10.1016/j.celrep.2022.111601

ssRNA Virus and Host Lipid Rearrangements: Is There a Role for Lipid Droplets in SARS-CoV-2 Infection?

Auteurs: Francesca Pagliari; Maria Grazia Marafioti; Geraldine Genard; Patrizio Candeloro; Giuseppe Viglietto; Joao Seco; Joao Seco; Luca Tirinato; Luca Tirinato
Publié dans: Frontiers in Molecular Biosciences, 2020, ISSN 2296-889X
Éditeur: Frontiers Media S.A
DOI: 10.3389/fmolb.2020.578964

Interrogation of endothelial and mural cells in brain metastasis reveals key immune-regulatory mechanisms

Auteurs: Leire Bejarano, Annamaria Kauzlaric, Eleni Lamprou, Joao Lourenco, Nadine Fournier, Michelle Ballabio, Roberto Colotti, Roeltje Maas, Sabine Galland, Matteo Massara, Klara Soukup, Johanna Lilja, Jean-Philippe Brouland, Andreas F. Hottinger, Roy T. Daniel, Monika E. Hegi, Johanna A. Joyce
Publié dans: Cancer Cell, 2024, ISSN 1535-6108
Éditeur: Cell Press
DOI: 10.1016/j.ccell.2023.12.018

BAP1 enhances Polycomb repression by counteracting widespread H2AK119ub1 deposition and chromatin condensation.

Auteurs: Eric Conway; Federico Rossi; Daniel Fernández-Pérez; Eleonora Ponzo; Karin Johanna Ferrari; Marika Zanotti; Daria Manganaro; Simona Rodighiero; Simone Tamburri; Simone Tamburri; Diego Pasini; Diego Pasini
Publié dans: Molecular Cell, Numéro 55, 2021, ISSN 1097-2765
Éditeur: Cell Press
DOI: 10.1016/j.molcel.2021.06.020

Leukotrienes, a potential target for Covid-19

Auteurs: Francesca Citron, Luigi Perelli, Angela K. Deem, Giannicola Genovese, Andrea Viale
Publié dans: Prostaglandins Leukot Essent Fatty Acids, 2020, ISSN 1532-2823
Éditeur: Elsevier Inc
DOI: 10.1016/j.plefa.2020.102174

Clonal dominance defines metastatic dissemination in pancreatic cancer

Auteurs: I-Lin Ho, Chieh-Yuan Li, Fuchenchu Wang , Li Zhao , Jingjing Liu , Er-Yen Yen, Charles A Dyke, Rutvi Shah , Zhaoliang Liu , Ali Osman Çetin , Yanshuo Chu , Francesca Citron , Sergio Attanasio, Denise Corti , Faezeh Darbaniyan , Edoardo Del Poggetto , Sara Loponte , Jintan Liu, Melinda Soeung , Ziheng Chen , Shan Jiang , Hong Jiang , Akira Inoue , Sisi Gao, Angela Deem , Ningping Feng , Haoqiang Y
Publié dans: SCIENCE ADVANCES, 2024, ISSN 2375-2548
Éditeur: American Association for the Advancement of Science
DOI: 10.1126/sciadv.add9342

Polymorphonuclear Myeloid-Derived Suppressor Cells Are Abundant in Peripheral Blood of Cancer Patients and Suppress Natural Killer Cell Anti-Tumor Activity

Auteurs: Nicola Tumino; Francesca Besi; Stefania Martini; Anna Laura Di Pace; Enrico Munari; Enrico Munari; Linda Quatrini; Andrea Pelosi; Piera Filomena Fiore; Giulia Fiscon; Giulia Fiscon; Paola Paci; Paola Paci; Francesca Scordamaglia; Maria Grazia Covesnon; Giuseppe Bogina; Maria Cristina Mingari; Maria Cristina Mingari; Lorenzo Moretta; Paola Vacca
Publié dans: Frontiers in Immunology, Numéro 27, 2022, ISSN 1664-3224
Éditeur: Frontiers Media
DOI: 10.3389/fimmu.2021.803014

New insights into the cell- and tissue-specificity of glucocorticoid actions.

Auteurs: Quatrini, Linda; Ugolini, Sophie
Publié dans: Cellular & Molecular Immunology, 2020, ISSN 1672-7681
Éditeur: Nature Publishing Group
DOI: 10.1038/s41423-020-00526-2

Correlative Raman–Electron–Light (CREL) Microscopy Analysis of Lipid Droplets in Melanoma Cancer Stem Cells

Auteurs: Francesca Pagliari; Elisa Sogne; Davide Panella; Gerardo Perozziello; Carlo Liberale; Gobind Das; Alice Turdo; Simone Di Franco; Joao Seco; Andrea Falqui; Santo Gratteri; Arturo Pujia; Enzo Di Fabrizio; Patrizio Candeloro; Luca Tirinato
Publié dans: Biosensors, Numéro 2, 2022, ISSN 2079-6374
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/bios12121102

Sialylation regulates migration in chronic lymphocytic leukemia

Auteurs: Natoni, Alessandro; Cerreto, Marina; De Propris, Maria Stefania; Del Giudice, Ilaria; Soscia, Roberta; Peragine, Nadia; Intoppa, Stefania; Milani, Maria Laura; Guarini, Anna; Foà, Robin
Publié dans: Haematologica, Numéro 48, 2023, ISSN 0390-6078
Éditeur: Ferrata Storti Foundation
DOI: 10.3324/haematol.2022.281999

Inhibition of JNK increases the sensitivity of hepatocellular carcinoma cells to lysosomotropic drugs via LAMP2A destabilization

Auteurs: Enrico Desideri & Maria Rosa Ciriolo
Publié dans: Cell Death Discovery, 2021, ISSN 2058-7716
Éditeur: Nature Publishing Group
DOI: 10.1038/s41420-021-00408-0

PD-1/PD-L1 in Cancer: Pathophysiological, Diagnostic and Therapeutic Aspects

Auteurs: Enrico Munari; Francesca Romana Mariotti; Linda Quatrini; Pietro Bertoglio; Nicola Tumino; Paola Vacca; Albino Eccher; Francesco Ciompi; Matteo Brunelli; Guido Martignoni; Giuseppe Bogina; Lorenzo Moretta
Publié dans: International Journal of Molecular Sciences, 2021, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22105123

Tissue resident iNKT17 cells facilitate cancer cell extravasation in liver metastasis via interleukin-22

Auteurs: Anastasios D Giannou , Jan Kempski , Ahmad Mustafa Shiri , Jöran Lücke , Tao Zhang , Lilan Zhao , Dimitra E Zazara Filippo Cortesi Kristoffer Riecken 7 Maria Carolina Amezcua Vesely , Jun Siong Low , Hao Xu , Eleanna Kaffe , Laura Garcia-Perez , Theodora Agalioti , Yoshito Yamada , Wolfgang Jungraithmayr 10, Ehud Zigmond Karl-Frederick Karstens , Babett Steglich , Jonas Wagner , Leonie Konczal
Publié dans: Immunity, 2023, ISSN 1074-7613
Éditeur: Cell Press
DOI: 10.1016/j.immuni.2022.12.014

TGF-β induces matrisome pathological alterations and EMT in patient-derived prostate cancer tumoroids

Auteurs: Soraia Fernandes; Jorge Oliver-De La Cruz; Marco Cassani; Sofia Morazzo; Helena Ďuríková; Alessio Caravella; Piergiuseppe Fiore; Giulia Azzato; Giuseppe De Marco; Agostino Lauria; Valerio Izzi; Veronika Bosáková; Jan Fric; Petr Filipensky; Giancarlo Forte
Publié dans: Matrix Biology, 2024, ISSN 0945-053X
Éditeur: Elsevier BV
DOI: 10.1016/j.matbio.2023.11.001

RAD54L2 counters TOP2-DNA adducts to promote genome stability

Auteurs: Giuseppina D'Alessandro , David A Morales-Juarez , Sean L Richards , Karin C Nitiss , Almudena Serrano-Benitez , Juanjuan Wang , John C Thomas , Vipul Gupta , Andrea Voigt , Rimma Belotserkovskaya , Chen Gang Goh , Anne Ramsay Bowden , Yaron Galanty , Petra Beli , John L Nitiss , Guido Zagnoli-Vieira , Stephen P Jackson
Publié dans: SCIENCE ADVANCES, 2023, ISSN 2375-2548
Éditeur: Washington DC: American Association for the Advancement of Science
DOI: 10.1126/sciadv.adl2108

Leveraging Tissue-Specific Enhancer–Target Gene Regulatory Networks Identifies Enhancer Somatic Mutations That Functionally Impact Lung Cancer

Auteurs: Judith Mary Hariprakash , Elisa Salviato , Federica La Mastra , Endre Sebestyén , Ilario Tagliaferri , Raquel Sofia Silva , Federica Lucini , Lorenzo Farina 1, Mario Cinquanta , Ilaria Rancati , Mirko Riboni , Simone Paolo Minardi , Luca Roz , Francesca Gorini , Chiara Lanzuolo , Stefano Casola , Francesco Ferrari
Publié dans: Cancer Research, 2024, ISSN 0008-5472
Éditeur: American Association for Cancer Research
DOI: 10.1158/0008-5472.can-23-1129

Impact of chromatin context on Cas9-induced DNA double-strand break repair pathway balance

Auteurs: Ruben Schep , Eva K Brinkman , Christ Leemans , Xabier Vergara , Robin H van der Weide , Ben Morris , Tom van Schaik , Stefano G Manzo , Daniel Peric-Hupkes , Jeroen van den Berg , Roderick L Beijersbergen , René H Medema , Bas van Steensel
Publié dans: Mol Cell ., 2021, ISSN 1097-2765
Éditeur: Cell Press
DOI: 10.1016/j.molcel.2021.03.032

Microbial short-chain fatty acids: a strategy to tune adoptive T cell therapy

Auteurs: Priya Rangan; Anna Mondino
Publié dans: Journal for ImmunoTherapy of Cancer, Numéro 1, 2022, ISSN 2051-1426
Éditeur: BMJ
DOI: 10.1136/jitc-2021-004147

Che-1/AATF-induced transcriptionally active chromatin promotes cell proliferation in multiple myeloma

Auteurs: Tiziana Bruno, Francesca De Nicola, Giacomo Corleone, Valeria Catena, Frauke Goeman, Matteo Pallocca, Cristina Sorino, Gianluca Bossi, Bruno Amadio, Giovanni Cigliana, Maria Rosaria Ricciardi, Maria Teresa Petrucci, Enrico Pierluigi Spugnini, Alfonso Baldi, Mario Cioce, Giancarlo Cortese, Elisabetta Mattei, Roberta Merola, Umberto Gianelli, Luca Baldini, Francesco Pisani, Svitlana Gumenyuk, Andrea
Publié dans: Blood Adv, 2020, ISSN 2473-9537
Éditeur: Elsevier Inc
DOI: 10.1182/bloodadvances.2020002566

The NAMPT Inhibitor FK866 in Combination with Cisplatin Reduces Cholangiocarcinoma Cells Growth

Auteurs: Kishor Pant; Seth Richard; Estanislao Peixoto; Jun Yin; Davis M. Seelig; Pietro Carotenuto; Massimiliano Salati; Brunella Franco; Lewis R. Roberts; Sergio A. Gradilone
Publié dans: Cells, Numéro 31, 2023, ISSN 2073-4409
Éditeur: MDPI
DOI: 10.3390/cells12050775

Inhibitory checkpoints in human natural killer cells: IUPHAR Review 28

Auteurs: Mariotti, F. R.; Quatrini, L.; Munari, E.; Vacca, P.; Tumino, N.; Pietra, G.; Mingari, M. C.; Moretta, L.
Publié dans: British Journal of Pharmacology, Numéro 25, 2020, ISSN 0007-1188
Éditeur: Wiley-Blackwell
DOI: 10.1111/bph.15081

Immune surveillance of the liver by T cells

Auteurs: Xenia Ficht, Matteo Iannacone
Publié dans: SCIENCE IMMUNOLOGY, 2020, ISSN 2470-9468
Éditeur: American Association for the Advancement of Science
DOI: 10.1126/sciimmunol.aba2351

Impaired degradation of YAP1 and IL6ST by chaperone-mediated autophagy promotes proliferation and migration of normal and hepatocellular carcinoma cells

Auteurs: Desideri, Enrico; Castelli, Serena; Dorard, Coralie; Toifl, Stefanie; Grazi, Gian Luca; Ciriolo, Maria Rosa; Baccarini, Manuela
Publié dans: Autophagy, Numéro 60, 2022, ISSN 1554-8627
Éditeur: Landes Bioscience
DOI: 10.1080/15548627.2022.2063004

Characterisation of innate lymphoid cell subsets infiltrating colorectal carcinoma

Auteurs: Paolo Carrega, Paola Orecchia, Linda Quatrini, Nicola Tumino, Roberta Venè, Roberto Benelli, Alessandro Poggi, Stefano Scabini, Maria Cristina Mingari, Lorenzo Moretta, Paola Vacca
Publié dans: Gut, 2020, Page(s) gutjnl-2020-320908, ISSN 0017-5749
Éditeur: BMJ Publishing Group
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Role of uL3 in the Crosstalk between Nucleolar Stress and Autophagy in Colon Cancer Cells

Auteurs: Annalisa Pecoraro, Pietro Carotenuto, Brunella Franco, Rossella De Cegli, Giulia Russo, Annapina Russo
Publié dans: International Journal of Molecular Sciences, Numéro 21/6, 2020, Page(s) 2143, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21062143

ILC3s: Rhythmic Keepers of Gut Integrity at Mealtime

Auteurs: Linda Quatrini, Lorenzo Moretta, Maria Cristina Mingari
Publié dans: Trends in Immunology, Numéro 41/5, 2020, Page(s) 364-366, ISSN 1471-4906
Éditeur: Elsevier BV
DOI: 10.1016/j.it.2020.03.011

A closer look into NADPH oxidase inhibitors: Validation and insight into their mechanism of action

Auteurs: Joana Reis, Marta Massari, Sara Marchese, Marta Ceccon, Friso S. Aalbers, Federica Corana, Sergio Valente, Antonello Mai, Francesca Magnani, Andrea Mattevi
Publié dans: Redox Biology, Numéro 32, 2020, Page(s) 101466, ISSN 2213-2317
Éditeur: Elsevier BV
DOI: 10.1016/j.redox.2020.101466

Targeting Glutathione Metabolism: Partner in Crime in Anticancer Therapy

Auteurs: Enrico Desideri, Fabio Ciccarone, Maria Rosa Ciriolo
Publié dans: Nutrients, Numéro 11/8, 2019, Page(s) 1926, ISSN 2072-6643
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
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Histone H2AK119 Mono-Ubiquitination Is Essential for Polycomb-Mediated Transcriptional Repression

Auteurs: Simone Tamburri, Elisa Lavarone, Daniel Fernández-Pérez, Eric Conway, Marika Zanotti, Daria Manganaro, Diego Pasini
Publié dans: Molecular Cell, Numéro 77/4, 2020, Page(s) 840-856.e5, ISSN 1097-2765
Éditeur: Cell Press
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Helper Innate Lymphoid Cells in Human Tumors: A Double-Edged Sword?

Auteurs: Nicola Tumino, Paola Vacca, Linda Quatrini, Enrico Munari, Francesca Moretta, Andrea Pelosi, Francesca Romana Mariotti, Lorenzo Moretta
Publié dans: Frontiers in Immunology, Numéro 10, 2020, ISSN 1664-3224
Éditeur: Front. Immunol.
DOI: 10.3389/fimmu.2019.03140

Keeping the Centromere under Control: A Promising Role for DNA Methylation

Auteurs: Scelfo, Fachinetti
Publié dans: Cells, Numéro 8/8, 2019, Page(s) 912, ISSN 2073-4409
Éditeur: MDPI
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Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition)

Auteurs: Cossarizza A.; Chang H. -D.; Radbruch A.; Abrignani S.; Addo R.; Akdis M.; Andra I.; Andreata F.; Annunziato F.; Arranz E.; Bacher P.; Bari S.; Barnaba V.; Barros-Martins J.; Baumjohann D.; Beccaria C. G.; Bernardo D.; Boardman D. A.; Borger J.; Bottcher C.; Brockmann L.; Burns M.; Busch D. H.; Cameron G.; Cammarata I.; Cassotta A.; Chang Y.; Chirdo F. G.; Christakou E.; Cicin-Sain L.; Cook L.; Co
Publié dans: European Journal of Immunology, 2021, ISSN 1521-4141
Éditeur: Wiley
DOI: 10.1002/eji.202170126

NK Cells and PMN-MDSCs in the Graft From G-CSF Mobilized Haploidentical Donors Display Distinct Gene Expression Profiles From Those of the Non-Mobilized Counterpart

Auteurs: Andrea, Pelosi; Francesca, Besi; Nicola, Tumino; Pietro, Merli; Linda, Quatrini; Giuseppina, Li Pira; Mattia, Algeri; Lorenzo, Moretta; Paola, Vacca
Publié dans: Frontiers in Immunology, Numéro 19, 2021, ISSN 1664-3224
Éditeur: Frontiers Media
DOI: 10.3389/fimmu.2021.657329

Human NK cells, their receptors and function

Auteurs: Linda Quatrini, Mariella Della Chiesa, Simona Sivori, Maria Cristina Mingari, Daniela Pende, Lorenzo Moretta
Publié dans: Eur J Immunol ., 2021, ISSN 0014-2980
Éditeur: John Wiley & Sons Ltd.
DOI: 10.1002/eji.202049028

The local microenvironment drives activation of neutrophils in human brain tumors

Auteurs: Roeltje R Maas , Klara Soukup , Nadine Fournier , Matteo Massara , Sabine Galland , Mara Kornete , Vladimir Wischnewski , Joao Lourenco , Davide Croci , Ángel F Álvarez-Prado , Damien N Marie , Johanna Lilja , Rachel Marcone6, Gabriel F Calvo , Rui Santalla Mendez , Pauline Aubel , Leire Bejarano , Pratyaksha Wirapati , Iván Ballesteros , Andrés Hidalgo , Andreas F Hottinger , Jean-Philippe Br
Publié dans: Cell, 2023, ISSN 2073-4409
Éditeur: MDPI AG
DOI: 10.1016/j.cell.2023.08.043

Insights Into Mechanisms of Oriented Division From Studies in 3D Cellular Models

Auteurs: Federico Donà; Susanna Eli; Marina Mapelli
Publié dans: Frontiers in Cell and Developmental Biology, Numéro 23, 2022, ISSN 2296-634X
Éditeur: Frontiers Media
DOI: 10.3389/fcell.2022.847801

Lipid Droplet Biosynthesis Impairment through DGAT2 Inhibition Sensitizes MCF7 Breast Cancer Cells to Radiation

Auteurs: Clelia Nisticò; Clelia Nisticò; Francesca Pagliari; Emanuela Chiarella; Joana F. Guerreiro; Joana F. Guerreiro; Maria Grazia Marafioti; Maria Grazia Marafioti; Ilenia Aversa; Ilenia Aversa; Geraldine Genard; Rachel Hanley; Rachel Hanley; Daniel Garcia-Calderón; Daniel Garcia-Calderón; Heather M. Bond; Maria Mesuraca; Luca Tirinato; Luca Tirinato; Maria Francesca Spadea; Joao Seco; Joao Seco
Publié dans: International Journal of Molecular Sciences, Numéro 1, 2021, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms221810102

The Evolving Role of FGFR2 Inhibitors in Intrahepatic Cholangiocarcinoma: From Molecular Biology to Clinical Targeting.

Auteurs: Salati M.; Caputo F.; Baldessari C.; Carotenuto P.; Messina M.; Caramaschi S.; Dominici M.; Bonetti L. R.
Publié dans: Cancer Management and Research, 2021, ISSN 1179-1322
Éditeur: Dove Medical Press Ltd
DOI: 10.2147/cmar.s330710

How the Immune System Responds to Allergy Immunotherapy

Auteurs: Irene Veneziani; Nadine Landolina; Biancamaria Ricci; Oliviero Rossi; Lorenzo Moretta; Enrico Maggi
Publié dans: Biomedicines, Numéro 1, 2022, ISSN 2227-9059
Éditeur: MDPI
DOI: 10.3390/biomedicines10112825

Transforming the Chemical Structure and Bio-Nano Activity of Doxorubicin by Ultrasound for Selective Killing of Cancer Cells

Auteurs: Sukhvir Kaur Bhangu, Soraia Fernandes, Giovanni Luca Beretta, Stella Tinelli, Marco Cassani, Agata Radziwon, Marcin Wojnilowicz, Sophia Sarpaki, Irinaios Pilatis, Nadia Zaffaroni, Giancarlo Forte, Frank Caruso, Muthupandian Ashokkumar, Francesca Cavalieri
Publié dans: Advanced Materials, 2022, ISSN 0935-9648
Éditeur: United Nations Industrial Developement Organization
DOI: 10.1002/adma.202107964

Combining β-Carotene with 5-FU via Polymeric Nanoparticles as a Novel Therapeutic Strategy to Overcome uL3-Mediated Chemoresistance in p53-Deleted Colorectal Cancer Cells

Auteurs: Carotenuto, Pietro; Pecoraro, Annalisa; Brignola, Chiara; Barbato, Anna; Franco, Brunella; Longobardi, Giuseppe; Conte, Claudia; Quaglia, Fabiana; Russo, Giulia; Russo, Annapina
Publié dans: Mol. Pharmaceutics, Numéro 18, 2023, ISSN 1543-8384
Éditeur: American Chemical Society
DOI: 10.1021/acs.molpharmaceut.2c00876

JMJD6 Shapes a Pro-tumor Microenvironment via ANXA1-Dependent Macrophage Polarization in Breast Cancer

Auteurs: Bianca Cioni ; Silvia Ratti ; Annamaria Piva ; Irene Tripodi ; Matteo Milani ; Francesca Menichetti ; Tiziana Langella ; Laura Botti ; Loris De Cecco ; Claudia Chiodoni ; Daniele Lecis ; Mario P. Colombo
Publié dans: Molecular Cancer Research, 2023, ISSN 1541-7786
Éditeur: American Association for Cancer Research
DOI: 10.1158/1541-7786.mcr-22-0370

An Elegant Four-Helical Fold in NOX and STEAP Enzymes Facilitates Electron Transport across Biomembranes—Similar Vehicle, Different Destination

Auteurs: Wout Oosterheert, Joana Reis, Piet Gros, Andrea Mattevi
Publié dans: Accounts of Chemical Research, Numéro 53, 2023, Page(s) 1969-1980, ISSN 0001-4842
Éditeur: American Chemical Society
DOI: 10.1021/acs.accounts.0c00400

Lipid droplets and ferritin heavy chain: a devilish liaison in human cancer cell radioresistance

Auteurs: Luca Tirinato Is a corresponding authorMaria Grazia MarafiotiFrancesca Pagliari Is a corresponding authorJeannette JansenIlenia AversaRachel HanleyClelia NisticòDaniel Garcia-CalderónGeraldine GenardJoana Filipa GuerreiroFrancesco Saverio CostanzoJoao Seco
Publié dans: Cancer Biology, 2021, ISSN 2079-7737
Éditeur: eLife Sciences Publications
DOI: 10.7554/elife.72943

Whole-genome CRISPR screening identifies PI3K/AKT as a downstream component of the oncogenic GNAQ–focal adhesion kinase signaling circuitry

Auteurs: Nadia Arang, Simone Lubrano, Damiano Cosimo Rigiracciolo, Daniela Nachmanson, Scott M. Lippman, Prashant Mali, Olivier Harismendy, J. Silvio Gutkind
Publié dans: J Biol Chem, 2023, ISSN 0021-9258
Éditeur: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1016/j.jbc.2022.102866

Tumor in 3D: In Vitro Complex Cellular Models to Improve Nanodrugs Cancer Therapy

Auteurs: Soraia Fernandes, Marco Cassani, Stefania Pagliari, Petr Filipensky, Francesca Cavalieri, Giancarlo Forte
Publié dans: Current Medicinal Chemistry, Numéro 27, 2021, Page(s) 7234-7255, ISSN 0929-8673
Éditeur: Bentham Science Publishers
DOI: 10.2174/0929867327666200625151134

NK cells and ILCs in tumor immunotherapy

Auteurs: Simona Sivori , Daniela Pende , Linda Quatrini , Gabriella Pietra, Mariella Della Chiesa , Paola Vacca , Nicola Tumino , Francesca Moretta , Maria Cristina Mingari , Franco Locatelli , Lorenzo Moretta
Publié dans: Molecular Aspects of Medicine, 2021, ISSN 0098-2997
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.mam.2020.100870

Cilia and Cancer: From Molecular Genetics to Therapeutic Strategies

Auteurs: Pietro Carotenuto; Sergio A. Gradilone; Brunella Franco
Publié dans: Genes, Numéro 50, 2023, ISSN 2073-4425
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/genes14071428

Interferon signaling promotes tolerance to chromosomal instability during metastatic evolution in renal cancer

Auteurs: Luigi Perelli, Federica Carbone, Li Zhang, Justin K. Huang, Courtney Le, Hania Khan, Francesca Citron, Edoardo Del Poggetto, Tony Gutschner, Hideo Tomihara, Melinda Soeung, Rosalba Minelli, Sanjana Srinivasan, Michael Peoples, Truong Nguyen Anh Lam, Sebastian Lundgren, Ruohan Xia, Cihui Zhu, Alaa M. T. Mohamed, Jianhua Zhang, Kanishka Sircar, Alessandro Sgambato, JianJun Gao, Eric Jonasch, Giulio
Publié dans: Nature Cancer, 2023, ISSN 2662-1347
Éditeur: Nature Portfolio
DOI: 10.1038/s43018-023-00584-1

Regulation of the Immune System Development by Glucocorticoids and Sex Hormones.

Auteurs: Quatrini L.; Ricci B.; Ciancaglini C.; Tumino N.; Moretta L.
Publié dans: Frontiers in Immunology, Numéro 9, 2021, ISSN 1664-3224
Éditeur: Frontiers Media
DOI: 10.3389/fimmu.2021.672853

Synthetic Lethal Screens Reveal Cotargeting FAK and MEK as a Multimodal Precision Therapy for GNAQ-Driven Uveal Melanoma

Auteurs: Justine S. Paradis; Monica Acosta ; Robert Saddawi-Konefka ; Ayush Kishore; Simone Lubrano ; Frederico Gomes ; Nadia Arang; Manoela Tiago; Silvia Coma; Xingyu Wu; Kyle Ford; Chi-Ping Day ; Glenn Merlino; Prashant Mali; Jonathan A. Pachter ; Takami Sato ; Andrew E. Aplin ; J. Silvio Gutkind
Publié dans: Clin Cancer Res, 2021, ISSN 1078-0432
Éditeur: American Association for Cancer Research
DOI: 10.1158/1078-0432.ccr-20-3363

Identification of a Kupffer cell subset capable of reverting the T cell dysfunction induced by hepatocellular priming

Auteurs: Giorgia De Simone , Francesco Andreata , Camille Bleriot , Valeria Fumagalli , Chiara Laura , José M Garcia-Manteiga , Pietro Di Lucia , Stefano Gilotto , Xenia Ficht , Federico F De Ponti , Elisa B Bono , Leonardo Giustini , Gioia Ambrosi , Marta Mainetti , Paola Zordan , Alexandre P Bénéchet , Micol Ravà , Svetoslav Chakarov , Federica Moalli , Marc Bajenoff , Luca G Guidotti , Florent Ginho
Publié dans: Immunity, 2021, ISSN 1074-7613
Éditeur: Cell Press
DOI: 10.1016/j.immuni.2021.05.005

High-throughput chemogenetic drug screening reveals PKC-RhoA/PKN as a targetable signaling vulnerability in GNAQ-driven uveal melanoma

Auteurs: Nadia Arang , Simone Lubrano , Michele Ceribelli , Damiano C Rigiracciolo , Robert Saddawi-Konefka , Farhoud Faraji , Sydney I Ramirez , Daehwan Kim , Frances A Tosto , Erica Stevenson , Yuan Zhou , Zhiyong Wang , Julius Bogomolovas , Alfredo A Molinolo , Danielle L Swaney , Nevan J Krogan , Jing Yang , Silvia Coma , Jonathan A Pachter , Andrew E Aplin , Dario R Alessi , Craig J Thomas , J Silvio
Publié dans: Cell Reports Medicine, 2023, ISSN 2666-3791
Éditeur: New York: Cell Pres Elsevier Inc.
DOI: 10.1016/j.xcrm.2023.101244

Inhibitory Receptors and Checkpoints in Human NK Cells, Implications for the Immunotherapy of Cancer.

Auteurs: Simona Sivori; Mariella Della Chiesa; Simona Carlomagno; Linda Quatrini; Enrico Munari; Paola Vacca; Nicola Tumino; Francesca Romana Mariotti; Maria Cristina Mingari; Maria Cristina Mingari; Daniela Pende; Lorenzo Moretta
Publié dans: Frontiers Media S.A, 2020, ISSN 1664-3224
Éditeur: Frontiers Media S.A
DOI: 10.3389/fimmu.2020.02156

Glucocorticoids inhibit human hematopoietic stem cell differentiation toward a common ILC precursor

Auteurs: Linda Quatrini, PhD Nicola Tumino, PhD Francesca Besi, MSc Cecilia Ciancaglini, MSc Federica Galaverna, MD, PhD Antonio Giacomo Grasso, MD Pietro Merli, MD Franco Locatelli, MD, PhD Paola Vacca, PhD Lorenzo Moretta, MD
Publié dans: J Allergy Clin Immunol ., 2022, ISSN 2213-2198
Éditeur: Elsevier
DOI: 10.1016/j.jaci.2021.10.012

Human Cancer Cell Radiation Response Investigated through Topological Analysis of 2D Cell Networks

Auteurs: Luca Tirinato, Valentina Onesto, Daniel Garcia-Calderon, Francesca Pagliari, Maria-Francesca Spadea, Joao Seco & Francesco Gentile
Publié dans: Annals of Biomedical Engineering, 2023, ISSN 0090-6964
Éditeur: Kluwer Academic Publishers
DOI: 10.1007/s10439-023-03215-z

Genome-Wide Mapping and Microscopy Visualization of Protein–DNA Interactions by pA-DamID

Auteurs: Tom van Schaik, Stefano G. Manzo & Bas van Steensel
Publié dans: Methods Mol Biol ., 2022, ISSN 1064-3745
Éditeur: Humana Press, Inc.
DOI: 10.1007/978-1-0716-2140-0_12

A non-dividing cell population with high pyruvate dehydrogenase kinase activity regulates metabolic heterogeneity and tumorigenesis in the intestine

Auteurs: Carlos Sebastian; Christina Ferrer; Maria Serra; Jee-Eun Choi; Nadia Ducano; Alessia Mira; Manasvi S. Shah; Sylwia A. Stopka; Andrew J. Perciaccante; Claudio Isella; Daniel Moya-Rull; Marianela Vara-Messler; Silvia Giordano; Elena Maldi; Niyati Desai; Diane E. Capen; Enzo Medico; Murat Cetinbas; Ruslan I. Sadreyev; Dennis Brown; Miguel N. Rivera; Anna Sapino; David T. Breault; Nathalie Y. R. Agar;
Publié dans: Nature Communications, Numéro 64, 2022, ISSN 2041-1723
Éditeur: Nature Publishing Group
DOI: 10.1038/s41467-022-29085-y

Autophagy and longevity: Evolutionary hints from hyper-longevous mammals

Auteurs: Andrea G. Locatelli, Simone Cenc
Publié dans: Front. Endocrinol, 2022, ISSN 1664-2392
Éditeur: Frontiers Media
DOI: 10.3389/fendo.2022.1085522

Single-cell imaging and transcriptomic analyses of firm adhesion between patient-derived cancer and endothelial cells under shear stress

Auteurs: Camilla Cerutti; Lucilla Luzi; Giulia De Michele; Valentina Gambino; Enrica Migliaccio; Pier Giuseppe Pelicci
Publié dans: Proc Natl Acad Sci U S A ., Numéro 26, 2024, ISSN 0027-8424
Éditeur: National Academy of Sciences
DOI: 10.12688/openreseurope.15989.1

Raman Spectroscopic Stratification of Multiple Myeloma Patients Based on Exosome Profiling.

Auteurs: Mario Vincenzo Russo; Luca Tirinato; Francesca Scionti; Maria Laura Coluccio; Gerardo Perozziello; Caterina Riillo; Vincenzo Mollace; Santo Gratteri; Natalia Malara; Maria Teresa Di Martino; Giuseppe Viglietto; Pierosandro Tagliaferri; Pierfrancesco Tassone; Marco Rossi; Patrizio Candeloro
Publié dans: ACS Omega, 2020, ISSN 2470-1343
Éditeur: ACS
DOI: 10.1021/acsomega.0c03813

PSGL-1 decorated with sialyl Lewisa/x promotes high affinity binding of myeloma cells to P-selectin but is dispensable for E-selectin engagement

Auteurs: Michael O’Dwyer, Lucy Kirkham-McCarthy, Marina Cerreto, Robin Foà & Alessandro Natoni
Publié dans: Scientific Reports, 2024, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-024-52212-2

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