International Cancer Research Fellowships - 2 | iCARE-2 | Projekt | Ergebnisse | H2020 | CORDIS

CORDIS bietet Links zu öffentlichen Ergebnissen und Veröffentlichungen von HORIZONT-Projekten.

Links zu Ergebnissen und Veröffentlichungen von RP7-Projekten sowie Links zu einigen Typen spezifischer Ergebnisse wie Datensätzen und Software werden dynamisch von OpenAIRE abgerufen.

Leistungen

Link to Euraxess website for first call for proposals

Link to Euraxess website for first call for proposals to inform the Project Officer on publishing each call for proposals, by sending the link to the Euraxess website and a screen shot of the related call announcement. Month 1

Link to Euraxess website for second call for proposals

Link to Euraxess website for second call for proposals to inform the Project Officer on publishing each call for proposals, by sending the link to the Euraxess website and a screen shot of the related call announcement. Month 13.

Report for Second call for proposals on dissemination activities

Report for Second call for proposals on dissemination activities; Month 24 (containing at least the following information): Dates of Call Publication and places where it was published (Supporting documents are required as images, screen shots, photos from events); Flyers, brochures, or other information produced; Presentations, conferences and meetings or other events; Published articles in the press (please list and attach only main articles); Any other means of advertising the programme.

Report for First call for proposals on dissemination activities

Report for First call for proposals on dissemination activities; Month 12 (containing at least the following information): - Dates of Call Publication and places where it was published (Supporting documents are required as images, screen shots, photos from events); - Flyers, brochures, or other information produced; - Presentations, conferences and meetings or other events; - Published articles in the press (list and attach only main articles); - Any other means of advertising the programme.

Veröffentlichungen

A Novel Analysis Method for Evaluating the Interplay of Oxygen and Ionizing Radiation at the Gene Level.

Autoren: Jeannette Jansen; Jeannette Jansen; Patricia Vieten; Patricia Vieten; Francesca Pagliari; Rachel Hanley; Rachel Hanley; Maria Grazia Marafioti; Luca Tirinato; Luca Tirinato; Joao Seco; Joao Seco
Veröffentlicht in: Frontiers in Genetics, 2021, ISSN 1664-8021
Herausgeber: Frontiers Media
DOI: 10.3389/fgene.2021.597635

PillarX: A Microfluidic Device to Profile Circulating Tumor Cell Clusters Based on Geometry, Deformability, and Epithelial State

Autoren: Brenda J. Green, Margherita Marazzini, Ben Hershey, Amir Fardin, Qingsen Li, Zongjie Wang, Giovanni Giangreco, Federica Pisati, Stefano Marchesi, Andrea Disanza, Emanuela Frittoli, Emanuele Martini, Serena Magni, Galina V. Beznoussenko, Claudio Vernieri, Riccardo Lobefaro, Dario Parazzoli, Paolo Maiuri, Kristina Havas, Mahmoud Labib, Sara Sigismund, Pier Paolo Di Fiore, Rosalind H. Gunby, Shana O.
Veröffentlicht in: Small ., 2022, ISSN 1613-6829
Herausgeber: Wiley-VCH GmbH, Weinheim
DOI: 10.1002/smll.202106097

IL-1R8 silencing improves the anti-tumor function of freshly isolated human NK cells

Autoren: Nadine Landolina; Francesca Romana Mariotti; Tiziano Ingegnere; Claudia Alicata; Biancamaria Ricci; Andrea Pelosi; Irene Veneziani; Bruno Giuseppe Azzarone; Cecilia Garlanda; Alberto Mantovani; Lorenzo Moretta; Enrico Maggi
Veröffentlicht in: Journal for ImmunoTherapy of Cancer, Ausgabe 11, 2022, ISSN 2051-1426
Herausgeber: BMJ
DOI: 10.1136/jitc-2021-003858

Integrated Genomics Identifies miR-181/TFAM Pathway as a Critical Driver of Drug Resistance in Melanoma

Autoren: Anna Barbato , Antonella Iuliano , Mariagrazia Volpe , Romina D'Alterio , Simona Brillante , Filomena Massa , Rossella De Cegli , Sabrina Carrella , Massimiliano Salati , Annapina Russo3, Giulia Russo , Sara Riccardo , Davide Cacchiarelli , Mariaelena Capone , Gabriele Madonna , Paolo A Ascierto , Brunella Franco , Alessia Indrieri , Pietro Carotenuto
Veröffentlicht in: Int J Mol Sci, 2021, ISSN 1422-0067
Herausgeber: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22041801

Emerging Strategies for Immunotherapy of Solid Tumors Using Lipid-Based Nanoparticles

Autoren: Soraia Fernandes, Marco Cassani, Francesca Cavalieri, Giancarlo Forte, Frank Caruso
Veröffentlicht in: Advanced Science, 2023, ISSN 2198-3844
Herausgeber: Wiley
DOI: 10.1002/advs.202305769

Interaction Between MDSC and NK Cells in Solid and Hematological Malignancies: Impact on HSCT.

Autoren: Nicola Tumino; Anna Laura Di Pace; Francesca Besi; Linda Quatrini; Paola Vacca; Lorenzo Moretta
Veröffentlicht in: Frontiers in Immunology, Ausgabe 49, 2021, ISSN 1664-3224
Herausgeber: Frontiers Media
DOI: 10.3389/fimmu.2021.638841

Radio-resistance of hypoxic tumors: exploring the effects of oxygen and X-ray radiation on non-small lung cancer cell lines

Autoren: Rachel Hanley; Francesca Pagliari; Daniel Garcia-Calderón; Joana Fernandes Guerreiro; Géraldine Genard; Jeannette Jansen; Clelia Nisticò; Maria Grazia Marafioti; Luca Tirinato; Joao Seco
Veröffentlicht in: Radiation Oncology, Ausgabe 21, 2023, ISSN 0360-3016
Herausgeber: Elsevier BV
DOI: 10.1186/s13014-023-02275-8

Generation and maturation of human iPSC-derived 3D organotypic cardiac microtissues in long-term culture

Autoren: Ece Ergir, Jorge Oliver-De La Cruz, Soraia Fernandes, Marco Cassani, Francesco Niro, Daniel Pereira-Sousa, Jan Vrbský, Vladimír Vinarský, Ana Rubina Perestrelo, Doriana Debellis, Natália Vadovičová, Stjepan Uldrijan, Francesca Cavalieri, Stefania Pagliari, Heinz Redl, Peter Ertl & Giancarlo Forte
Veröffentlicht in: Scientific Reports, 2022, ISSN 2045-2322
Herausgeber: Nature Publishing Group
DOI: 10.1038/s41598-022-22225-w

The Role of the Microenvironment and Cell Adhesion Molecules in Chronic Lymphocytic Leukemia

Autoren: Marina Cerreto,Robin Foà andmAlessandro Natoni
Veröffentlicht in: Cancers, 2023, ISSN 2072-6694
Herausgeber: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers15215160

Diphenylene Iodonium Is a Noncovalent MAO Inhibitor: A Biochemical and Structural Analysis

Autoren: Luca G. Iacovino, Dr. Joana Reis, Prof. Antonello Mai, Prof. Claudia Binda, Prof. Andrea Mattevi
Veröffentlicht in: ChemMedChem, 2020, ISSN 1860-7187
Herausgeber: Wiley-VCH
DOI: 10.1002/cmdc.202000264

Group 1 ILCs regulate T cell–mediated liver immunopathology by controlling local IL-2 availability

Autoren: Valeria Fumagalli , Valentina Venzin , Pietro Di Lucia , Federica Moalli , Xenia Ficht , Gioia Ambrosi , Leonardo Giustini 1, Francesco Andreata , Marta Grillo , Diletta Magini , Micol Ravà , Christin Friedrich , Jason D Fontenot , Philippe Bousso , Sarah A Gilmore , Shahzada Khan , Manuel Baca , Eric Vivier, Georg Gasteiger , Mirela Kuka , Luca G Guidotti , Matteo Iannacone
Veröffentlicht in: Sci Immunol ., 2022, ISSN 2470-9468
Herausgeber: American Association for the Advancement of Science
DOI: 10.1126/sciimmunol.abi6112

The Immune Checkpoint PD-1 in Natural Killer Cells: Expression, Function and Targeting in Tumour Immunotherapy

Autoren: Linda Quatrini, Francesca Romana Mariotti, Enrico Munari, Nicola Tumino, Paola Vacca, Lorenzo Moretta
Veröffentlicht in: Cancers, Ausgabe 12, 2024, Seite(n) 3285, ISSN 2072-6694
Herausgeber: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12113285

Cell-Membrane-Coated and Cell-Penetrating Peptide-Conjugated Trimagnetic Nanoparticles for Targeted Magnetic Hyperthermia of Prostate Cancer Cells

Autoren: Valentin Nica; Attilio Marino; Carlotta Pucci; Özlem Şen; Melis Emanet; Daniele De Pasquale; Alessio Carmignani; Andrea Petretto; Martina Bartolucci; Simone Lauciello; Rosaria Brescia; Francesco de Boni; Mirko Prato; Sergio Marras; Filippo Drago; Mohaned Hammad; Doris Segets; Gianni Ciofani
Veröffentlicht in: ACS Appl. Mater. Interfaces, Ausgabe 1, 2023, ISSN 1944-8244
Herausgeber: American Chemical Society
DOI: 10.1021/acsami.3c07248

Dynamic chromosomal interactions and control of heterochromatin positioning by Ki67

Autoren: van Schaik, Tom; Manzo, Stefano G; Vouzas, Athanasios E; Liu, Ning Qing; Teunissen, Hans; de Wit, Elzo; Gilbert, David M; van Steensel, Bas
Veröffentlicht in: EMBO Rep, Ausgabe 32, 2022, ISSN 1469-221X
Herausgeber: Nature Publishing Group
DOI: 10.1101/2021.10.20.465140

The Pervasive Role of the miR-181 Family in Development, Neurodegeneration, and Cancer

Autoren: Alessia Indrieri ,Sabrina Carrella ,Pietro Carotenuto ,Sandro Banfi, Brunella Franco
Veröffentlicht in: International Journal of Molecular Sciences, 2020, ISSN 1422-0067
Herausgeber: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21062092

Human lung-cancer-cell radioresistance investigated through 2D network topology

Autoren: Luca Tirinato; Valentina Onesto; Daniel Garcia-Calderon; Francesca Pagliari; Maria-Francesca Spadea; Joao Seco; Francesco Gentile
Veröffentlicht in: Scientific Reports, Ausgabe 15, 2022, ISSN 2045-2322
Herausgeber: Nature Publishing Group
DOI: 10.1038/s41598-022-17018-0

AATF/Che‐1 localizes to paraspeckles and suppresses R‐loops accumulation and interferon activation in Multiple Myeloma

Autoren: Tiziana Bruno, Giacomo Corleone, Valeria Catena , Clelia Cortile , Francesca De Nicola, Francesca Fabretti, Svitlana Gumenyuk, Francesco Pisani, Andrea Mengarelli , Claudio Passananti, and Maurizio Fanciulli
Veröffentlicht in: EMBO J, 2022, ISSN 0261-4189
Herausgeber: Nature Publishing Group
DOI: 10.15252/embj.2021109711

Glucocorticoids and the cytokines IL-12, IL-15, and IL-18 present in the tumor microenvironment induce PD-1 expression on human natural killer cells.

Autoren: Linda Quatrini; Paola Vacca; Nicola Tumino; Francesca Besi; Anna Laura Di Pace; Francesca Scordamaglia; Stefania Martini; Enrico Munari; Maria Cristina Mingari; Sophie Ugolini; Lorenzo Moretta
Veröffentlicht in: Journal of Allergy and Clinical Immunology, Ausgabe 7, 2021, ISSN 0091-6749
Herausgeber: Mosby Inc.
DOI: 10.1016/j.jaci.2020.04.044

Sialofucosylation Enables Platelet Binding to Myeloma Cells via P-Selectin and Suppresses NK Cell-Mediated Cytotoxicity

Autoren: Alessandro Natoni; Marina Cerreto; Maria Stefania De Propris; Maria Teresa Petrucci; Francesca Fazio; Stefania Intoppa; Maria Laura Milani; Lucy Kirkham-McCarthy; Robert Henderson; Dawn Swan; Anna Guarini; Michael O’Dwyer; Robin Foà
Veröffentlicht in: Cancers, Ausgabe 1, 2023, ISSN 2072-6694
Herausgeber: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers15072154

ROS and Lipid Droplet accumulation induced by high glucose exposure in healthy colon and Colorectal Cancer Stem Cells.

Autoren: Luca Tirinato; Luca Tirinato; Luca Tirinato; Francesca Pagliari; Francesca Pagliari; Simone Di Franco; Elisa Sogne; Maria Grazia Marafioti; Jeanette Jansen; Jeanette Jansen; Andrea Falqui; Matilde Todaro; Patrizio Candeloro; Carlo Liberale; Joao Seco; Joao Seco; Giorgio Stassi; Enzo Di Fabrizio
Veröffentlicht in: Genes and Diseases, Ausgabe 1, 2020, ISSN 2352-3042
Herausgeber: Beijing: Publishing services by Elsevier B.V. on behalf of KeAi Communications Co. Ltd.
DOI: 10.1016/j.gendis.2019.09.010

Toll-like receptor 8 agonists improve NK-cell function primarily targeting CD56<sup>bright</sup>CD16<sup>−</sup> subset

Autoren: Irene Veneziani; Claudia Alicata; Andrea Pelosi; Nadine Landolina; Biancamaria Ricci; Valentina D'Oria; Anna Fagotti; Giovanni Scambia; Lorenzo Moretta; Enrico Maggi
Veröffentlicht in: Journal for ImmunoTherapy of Cancer, Ausgabe 1, 2022, ISSN 2051-1426
Herausgeber: BMJ
DOI: 10.1136/jitc-2021-003385

Generation and Characterization of a Tumor Stromal Microenvironment and Analysis of Its Interplay with Breast Cancer Cells: An In Vitro Model to Study Breast Cancer-Associated Fibroblast Inactivation

Autoren: Veronica Romano; Maria Rosaria Ruocco; Pietro Carotenuto; Anna Barbato; Alessandro Venuta; Vittoria Acampora; Sabrina De Lella; Elena Vigliar; Antonino Iaccarino; Giancarlo Troncone; Gaetano Calì; Luigi Insabato; Daniela Russo; Brunella Franco; Stefania Masone; Nunzio Velotti; Antonello Accurso; Tommaso Pellegrino; Giuseppe Fiume; Immacolata Belviso; Stefania Montagnani; Angelica Avagliano; Aless
Veröffentlicht in: International Journal of Molecular Sciences, Ausgabe 15, 2022, ISSN 1422-0067
Herausgeber: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23126875

miR-9 modulates and predicts the response to radiotherapy and EGFR inhibition in HNSCC.

Autoren: Francesca Citron; Francesca Citron; Ilenia Segatto; Lorena Musco; Ilenia Pellarin; Gian Luca Rampioni Vinciguerra; Gian Luca Rampioni Vinciguerra; Giovanni Franchin; Giuseppe Fanetti; Francesco Miccichè; Vittorio Giacomarra; Valentina Lupato; Andrea Favero; Isabella Concina; Sanjana Srinivasan; Michele Avanzo; Isabella Castiglioni; Isabella Castiglioni; Luigi Barzan; Sandro Sulfaro; Gianluigi Pet
Veröffentlicht in: EMBO Molecular Medicine, Ausgabe 24, 2021, ISSN 1757-4676
Herausgeber: John Wiley & Sons Ltd.
DOI: 10.15252/emmm.202012872

Polymorphonuclear myeloid-derived suppressor cells impair the anti-tumor efficacy of GD2.CAR T-cells in patients with neuroblastoma.

Autoren: Nicola Tumino; Gerrit Weber; Francesca Besi; Francesca Del Bufalo; Valentina Bertaina; Paola Paci; Linda Quatrini; Laura Antonucci; Matilde Sinibaldi; Concetta Quintarelli; Enrico Maggi; Biagio De Angelis; Franco Locatelli; Franco Locatelli; Lorenzo Moretta; Paola Vacca; Ignazio Caruana
Veröffentlicht in: Journal of Hematology & Oncology, Ausgabe 28, 2021, ISSN 1756-8722
Herausgeber: BioMed Central
DOI: 10.1186/s13045-021-01193-0

The Replication Stress Response on a Narrow Path Between Genomic Instability and Inflammation.

Autoren: Hervé Técher; Philippe Pasero
Veröffentlicht in: Frontiers in Cell and Developmental Biology, Ausgabe 54, 2021, ISSN 2296-634X
Herausgeber: Frontiers Media S.A
DOI: 10.3389/fcell.2021.702584

Micro-RNA in Cholangiocarcinoma: Implications for Diagnosis, Prognosis, and Therapy

Autoren: Anna Barbato; Fabiola Piscopo; Massimiliano Salati; Luca Reggiani-Bonetti; Brunella Franco; Pietro Carotenuto
Veröffentlicht in: Journal of Molecular Pathology, Ausgabe 1, 2022, ISSN 2673-5261
Herausgeber: MDPI AG, 2020
DOI: 10.3390/jmp3020009

Bone marrow vasculature advanced in vitro models for cancer and cardiovascular research

Autoren: Marzia Campanile,Leonardo Bettinelli Camilla Cerutti Gaia Spinetti1
Veröffentlicht in: Front. Cardiovasc. Med, 2023, ISSN 2297-055X
Herausgeber: Frontiers media
DOI: 10.3389/fcvm.2023.1261849

YAP signaling regulates the cellular uptake and therapeutic effect of nanoparticles

Autoren: Marco Cassani; Soraia Fernandes; Jorge Oliver‐De La Cruz; Helena Durikova; Jan Vrbsky; Marek Patočka; Veronika Hegrova; Simon Klimovic; Jan Pribyl; Doriana Debellis; Petr Skladal; Francesca Cavalieri; Frank Caruso; Giancarlo Forte
Veröffentlicht in: Advanced Science, Ausgabe 33, 2023, ISSN 2198-3844
Herausgeber: Wiley-VCH, 2014
DOI: 10.1101/2023.03.10.532035

Dissecting Clonal Hematopoiesis in Tissues of Patients with Classic Hodgkin Lymphoma

Autoren: Alessandra Venanzi; Andrea Marra ; Gianluca Schiavoni; Sara G. Milner; Roberto Limongello; Alessia Santi; Valentina Pettirossi; Simona Ultimo; Luisa Tasselli ; Alessandra Pucciarini; Lorenza Falini ; Sofia Sciabolacci; Maria Paola Martelli ; Paolo Sportoletti; Stefano Ascani; Brunangelo Falini ; Enrico Tiacci
Veröffentlicht in: Blood Cancer Discov, 2021, ISSN 2643-3249
Herausgeber: American Association for Cancer Research, Inc
DOI: 10.1158/2643-3230.bcd-20-0203

Microbiota-derived 3-IAA influences chemotherapy efficacy in pancreatic cancer

Autoren: Joseph Tintelnot, Yang Xu, Till R. Lesker, Martin Schönlein, Leonie Konczalla, Anastasios D. Giannou, Penelope Pelczar, Dominik Kylies, Victor G. Puelles, Agata A. Bielecka, Manuela Peschka, Filippo Cortesi, Kristoffer Riecken, Maximilian Jung, Lena Amend, Tobias S. Bröring, Marija Trajkovic-Arsic, Jens T. Siveke, Thomas Renné, Danmei Zhang, Stefan Boeck, Till Strowig, Faik G. Uzunoglu, Cenap G
Veröffentlicht in: Nature, 2023, ISSN 1476-4687
Herausgeber: Springer Nature
DOI: 10.1038/s41586-023-05728-y

Helper Innate Lymphoid Cells in Allogenic Hematopoietic Stem Cell Transplantation and Graft Versus Host Disease

Autoren: Linda Quatrini; Nicola Tumino; Francesca Moretta; Francesca Besi; Paola Vacca; Lorenzo Moretta
Veröffentlicht in: Frontiers in Immunology, 2020, ISSN 1664-3224
Herausgeber: Frontiers Media S.A
DOI: 10.3389/fimmu.2020.582098

The anti-inflammatory cytokine IL-37 improves the NK cell-mediated anti-tumor response

Autoren: Nadine Landolina,Francesca Romana MariottiORCID Icon,Andrea Pelosi,Valentina D’Oria,Tiziano Ingegnere,Claudia Alicata, Paola vacca, Lorenzo Moretta, Enrico Maggi
Veröffentlicht in: OncoImmunology, 2023, ISSN 2162-402X
Herausgeber: Taylor and Francis Online
DOI: 10.1080/2162402x.2023.2297504

Targeting the MITF/APAF-1 axis as salvage therapy for MAPK inhibitors in resistant melanoma

Autoren: Pietro Carotenuto, Alessia Romano, Anna Barbato, Paola Quadrano, Simona Brillante, Mariagrazia Volpe, Luigi Ferrante, Roberta Tammaro, Manuela Morleo, Rossella De Cegli, Antonella Iuliano, Marialuisa Testa, Fabrizio Andreone, Gennaro Ciliberto, Eduardo Clery, Giancarlo Troncone, Giuseppe Palma, Claudio Arra, Antonio Barbieri, Mariaelena Capone, Gabriele Madonna, Paolo A. Ascierto, Luisa Lanfrancon
Veröffentlicht in: Cell Reports, Ausgabe 41, 2023, Seite(n) 111601, ISSN 2211-1247
Herausgeber: Cell Press
DOI: 10.1016/j.celrep.2022.111601

ssRNA Virus and Host Lipid Rearrangements: Is There a Role for Lipid Droplets in SARS-CoV-2 Infection?

Autoren: Francesca Pagliari; Maria Grazia Marafioti; Geraldine Genard; Patrizio Candeloro; Giuseppe Viglietto; Joao Seco; Joao Seco; Luca Tirinato; Luca Tirinato
Veröffentlicht in: Frontiers in Molecular Biosciences, 2020, ISSN 2296-889X
Herausgeber: Frontiers Media S.A
DOI: 10.3389/fmolb.2020.578964

Interrogation of endothelial and mural cells in brain metastasis reveals key immune-regulatory mechanisms

Autoren: Leire Bejarano, Annamaria Kauzlaric, Eleni Lamprou, Joao Lourenco, Nadine Fournier, Michelle Ballabio, Roberto Colotti, Roeltje Maas, Sabine Galland, Matteo Massara, Klara Soukup, Johanna Lilja, Jean-Philippe Brouland, Andreas F. Hottinger, Roy T. Daniel, Monika E. Hegi, Johanna A. Joyce
Veröffentlicht in: Cancer Cell, 2024, ISSN 1535-6108
Herausgeber: Cell Press
DOI: 10.1016/j.ccell.2023.12.018

BAP1 enhances Polycomb repression by counteracting widespread H2AK119ub1 deposition and chromatin condensation.

Autoren: Eric Conway; Federico Rossi; Daniel Fernández-Pérez; Eleonora Ponzo; Karin Johanna Ferrari; Marika Zanotti; Daria Manganaro; Simona Rodighiero; Simone Tamburri; Simone Tamburri; Diego Pasini; Diego Pasini
Veröffentlicht in: Molecular Cell, Ausgabe 55, 2021, ISSN 1097-2765
Herausgeber: Cell Press
DOI: 10.1016/j.molcel.2021.06.020

Leukotrienes, a potential target for Covid-19

Autoren: Francesca Citron, Luigi Perelli, Angela K. Deem, Giannicola Genovese, Andrea Viale
Veröffentlicht in: Prostaglandins Leukot Essent Fatty Acids, 2020, ISSN 1532-2823
Herausgeber: Elsevier Inc
DOI: 10.1016/j.plefa.2020.102174

Clonal dominance defines metastatic dissemination in pancreatic cancer

Autoren: I-Lin Ho, Chieh-Yuan Li, Fuchenchu Wang , Li Zhao , Jingjing Liu , Er-Yen Yen, Charles A Dyke, Rutvi Shah , Zhaoliang Liu , Ali Osman Çetin , Yanshuo Chu , Francesca Citron , Sergio Attanasio, Denise Corti , Faezeh Darbaniyan , Edoardo Del Poggetto , Sara Loponte , Jintan Liu, Melinda Soeung , Ziheng Chen , Shan Jiang , Hong Jiang , Akira Inoue , Sisi Gao, Angela Deem , Ningping Feng , Haoqiang Y
Veröffentlicht in: SCIENCE ADVANCES, 2024, ISSN 2375-2548
Herausgeber: American Association for the Advancement of Science
DOI: 10.1126/sciadv.add9342

Polymorphonuclear Myeloid-Derived Suppressor Cells Are Abundant in Peripheral Blood of Cancer Patients and Suppress Natural Killer Cell Anti-Tumor Activity

Autoren: Nicola Tumino; Francesca Besi; Stefania Martini; Anna Laura Di Pace; Enrico Munari; Enrico Munari; Linda Quatrini; Andrea Pelosi; Piera Filomena Fiore; Giulia Fiscon; Giulia Fiscon; Paola Paci; Paola Paci; Francesca Scordamaglia; Maria Grazia Covesnon; Giuseppe Bogina; Maria Cristina Mingari; Maria Cristina Mingari; Lorenzo Moretta; Paola Vacca
Veröffentlicht in: Frontiers in Immunology, Ausgabe 27, 2022, ISSN 1664-3224
Herausgeber: Frontiers Media
DOI: 10.3389/fimmu.2021.803014

New insights into the cell- and tissue-specificity of glucocorticoid actions.

Autoren: Quatrini, Linda; Ugolini, Sophie
Veröffentlicht in: Cellular & Molecular Immunology, 2020, ISSN 1672-7681
Herausgeber: Nature Publishing Group
DOI: 10.1038/s41423-020-00526-2

Correlative Raman–Electron–Light (CREL) Microscopy Analysis of Lipid Droplets in Melanoma Cancer Stem Cells

Autoren: Francesca Pagliari; Elisa Sogne; Davide Panella; Gerardo Perozziello; Carlo Liberale; Gobind Das; Alice Turdo; Simone Di Franco; Joao Seco; Andrea Falqui; Santo Gratteri; Arturo Pujia; Enzo Di Fabrizio; Patrizio Candeloro; Luca Tirinato
Veröffentlicht in: Biosensors, Ausgabe 2, 2022, ISSN 2079-6374
Herausgeber: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/bios12121102

Sialylation regulates migration in chronic lymphocytic leukemia

Autoren: Natoni, Alessandro; Cerreto, Marina; De Propris, Maria Stefania; Del Giudice, Ilaria; Soscia, Roberta; Peragine, Nadia; Intoppa, Stefania; Milani, Maria Laura; Guarini, Anna; Foà, Robin
Veröffentlicht in: Haematologica, Ausgabe 48, 2023, ISSN 0390-6078
Herausgeber: Ferrata Storti Foundation
DOI: 10.3324/haematol.2022.281999

Inhibition of JNK increases the sensitivity of hepatocellular carcinoma cells to lysosomotropic drugs via LAMP2A destabilization

Autoren: Enrico Desideri & Maria Rosa Ciriolo
Veröffentlicht in: Cell Death Discovery, 2021, ISSN 2058-7716
Herausgeber: Nature Publishing Group
DOI: 10.1038/s41420-021-00408-0

PD-1/PD-L1 in Cancer: Pathophysiological, Diagnostic and Therapeutic Aspects

Autoren: Enrico Munari; Francesca Romana Mariotti; Linda Quatrini; Pietro Bertoglio; Nicola Tumino; Paola Vacca; Albino Eccher; Francesco Ciompi; Matteo Brunelli; Guido Martignoni; Giuseppe Bogina; Lorenzo Moretta
Veröffentlicht in: International Journal of Molecular Sciences, 2021, ISSN 1422-0067
Herausgeber: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22105123

Tissue resident iNKT17 cells facilitate cancer cell extravasation in liver metastasis via interleukin-22

Autoren: Anastasios D Giannou , Jan Kempski , Ahmad Mustafa Shiri , Jöran Lücke , Tao Zhang , Lilan Zhao , Dimitra E Zazara Filippo Cortesi Kristoffer Riecken 7 Maria Carolina Amezcua Vesely , Jun Siong Low , Hao Xu , Eleanna Kaffe , Laura Garcia-Perez , Theodora Agalioti , Yoshito Yamada , Wolfgang Jungraithmayr 10, Ehud Zigmond Karl-Frederick Karstens , Babett Steglich , Jonas Wagner , Leonie Konczal
Veröffentlicht in: Immunity, 2023, ISSN 1074-7613
Herausgeber: Cell Press
DOI: 10.1016/j.immuni.2022.12.014

TGF-β induces matrisome pathological alterations and EMT in patient-derived prostate cancer tumoroids

Autoren: Soraia Fernandes; Jorge Oliver-De La Cruz; Marco Cassani; Sofia Morazzo; Helena Ďuríková; Alessio Caravella; Piergiuseppe Fiore; Giulia Azzato; Giuseppe De Marco; Agostino Lauria; Valerio Izzi; Veronika Bosáková; Jan Fric; Petr Filipensky; Giancarlo Forte
Veröffentlicht in: Matrix Biology, 2024, ISSN 0945-053X
Herausgeber: Elsevier BV
DOI: 10.1016/j.matbio.2023.11.001

RAD54L2 counters TOP2-DNA adducts to promote genome stability

Autoren: Giuseppina D'Alessandro , David A Morales-Juarez , Sean L Richards , Karin C Nitiss , Almudena Serrano-Benitez , Juanjuan Wang , John C Thomas , Vipul Gupta , Andrea Voigt , Rimma Belotserkovskaya , Chen Gang Goh , Anne Ramsay Bowden , Yaron Galanty , Petra Beli , John L Nitiss , Guido Zagnoli-Vieira , Stephen P Jackson
Veröffentlicht in: SCIENCE ADVANCES, 2023, ISSN 2375-2548
Herausgeber: Washington DC: American Association for the Advancement of Science
DOI: 10.1126/sciadv.adl2108

Leveraging Tissue-Specific Enhancer–Target Gene Regulatory Networks Identifies Enhancer Somatic Mutations That Functionally Impact Lung Cancer

Autoren: Judith Mary Hariprakash , Elisa Salviato , Federica La Mastra , Endre Sebestyén , Ilario Tagliaferri , Raquel Sofia Silva , Federica Lucini , Lorenzo Farina 1, Mario Cinquanta , Ilaria Rancati , Mirko Riboni , Simone Paolo Minardi , Luca Roz , Francesca Gorini , Chiara Lanzuolo , Stefano Casola , Francesco Ferrari
Veröffentlicht in: Cancer Research, 2024, ISSN 0008-5472
Herausgeber: American Association for Cancer Research
DOI: 10.1158/0008-5472.can-23-1129

Impact of chromatin context on Cas9-induced DNA double-strand break repair pathway balance

Autoren: Ruben Schep , Eva K Brinkman , Christ Leemans , Xabier Vergara , Robin H van der Weide , Ben Morris , Tom van Schaik , Stefano G Manzo , Daniel Peric-Hupkes , Jeroen van den Berg , Roderick L Beijersbergen , René H Medema , Bas van Steensel
Veröffentlicht in: Mol Cell ., 2021, ISSN 1097-2765
Herausgeber: Cell Press
DOI: 10.1016/j.molcel.2021.03.032

Microbial short-chain fatty acids: a strategy to tune adoptive T cell therapy

Autoren: Priya Rangan; Anna Mondino
Veröffentlicht in: Journal for ImmunoTherapy of Cancer, Ausgabe 1, 2022, ISSN 2051-1426
Herausgeber: BMJ
DOI: 10.1136/jitc-2021-004147

Che-1/AATF-induced transcriptionally active chromatin promotes cell proliferation in multiple myeloma

Autoren: Tiziana Bruno, Francesca De Nicola, Giacomo Corleone, Valeria Catena, Frauke Goeman, Matteo Pallocca, Cristina Sorino, Gianluca Bossi, Bruno Amadio, Giovanni Cigliana, Maria Rosaria Ricciardi, Maria Teresa Petrucci, Enrico Pierluigi Spugnini, Alfonso Baldi, Mario Cioce, Giancarlo Cortese, Elisabetta Mattei, Roberta Merola, Umberto Gianelli, Luca Baldini, Francesco Pisani, Svitlana Gumenyuk, Andrea
Veröffentlicht in: Blood Adv, 2020, ISSN 2473-9537
Herausgeber: Elsevier Inc
DOI: 10.1182/bloodadvances.2020002566

The NAMPT Inhibitor FK866 in Combination with Cisplatin Reduces Cholangiocarcinoma Cells Growth

Autoren: Kishor Pant; Seth Richard; Estanislao Peixoto; Jun Yin; Davis M. Seelig; Pietro Carotenuto; Massimiliano Salati; Brunella Franco; Lewis R. Roberts; Sergio A. Gradilone
Veröffentlicht in: Cells, Ausgabe 31, 2023, ISSN 2073-4409
Herausgeber: MDPI
DOI: 10.3390/cells12050775

Inhibitory checkpoints in human natural killer cells: IUPHAR Review 28

Autoren: Mariotti, F. R.; Quatrini, L.; Munari, E.; Vacca, P.; Tumino, N.; Pietra, G.; Mingari, M. C.; Moretta, L.
Veröffentlicht in: British Journal of Pharmacology, Ausgabe 25, 2020, ISSN 0007-1188
Herausgeber: Wiley-Blackwell
DOI: 10.1111/bph.15081

Immune surveillance of the liver by T cells

Autoren: Xenia Ficht, Matteo Iannacone
Veröffentlicht in: SCIENCE IMMUNOLOGY, 2020, ISSN 2470-9468
Herausgeber: American Association for the Advancement of Science
DOI: 10.1126/sciimmunol.aba2351

Impaired degradation of YAP1 and IL6ST by chaperone-mediated autophagy promotes proliferation and migration of normal and hepatocellular carcinoma cells

Autoren: Desideri, Enrico; Castelli, Serena; Dorard, Coralie; Toifl, Stefanie; Grazi, Gian Luca; Ciriolo, Maria Rosa; Baccarini, Manuela
Veröffentlicht in: Autophagy, Ausgabe 60, 2022, ISSN 1554-8627
Herausgeber: Landes Bioscience
DOI: 10.1080/15548627.2022.2063004

Characterisation of innate lymphoid cell subsets infiltrating colorectal carcinoma

Autoren: Paolo Carrega, Paola Orecchia, Linda Quatrini, Nicola Tumino, Roberta Venè, Roberto Benelli, Alessandro Poggi, Stefano Scabini, Maria Cristina Mingari, Lorenzo Moretta, Paola Vacca
Veröffentlicht in: Gut, 2020, Seite(n) gutjnl-2020-320908, ISSN 0017-5749
Herausgeber: BMJ Publishing Group
DOI: 10.1136/gutjnl-2020-320908

Role of uL3 in the Crosstalk between Nucleolar Stress and Autophagy in Colon Cancer Cells

Autoren: Annalisa Pecoraro, Pietro Carotenuto, Brunella Franco, Rossella De Cegli, Giulia Russo, Annapina Russo
Veröffentlicht in: International Journal of Molecular Sciences, Ausgabe 21/6, 2020, Seite(n) 2143, ISSN 1422-0067
Herausgeber: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21062143

ILC3s: Rhythmic Keepers of Gut Integrity at Mealtime

Autoren: Linda Quatrini, Lorenzo Moretta, Maria Cristina Mingari
Veröffentlicht in: Trends in Immunology, Ausgabe 41/5, 2020, Seite(n) 364-366, ISSN 1471-4906
Herausgeber: Elsevier BV
DOI: 10.1016/j.it.2020.03.011

A closer look into NADPH oxidase inhibitors: Validation and insight into their mechanism of action

Autoren: Joana Reis, Marta Massari, Sara Marchese, Marta Ceccon, Friso S. Aalbers, Federica Corana, Sergio Valente, Antonello Mai, Francesca Magnani, Andrea Mattevi
Veröffentlicht in: Redox Biology, Ausgabe 32, 2020, Seite(n) 101466, ISSN 2213-2317
Herausgeber: Elsevier BV
DOI: 10.1016/j.redox.2020.101466

Targeting Glutathione Metabolism: Partner in Crime in Anticancer Therapy

Autoren: Enrico Desideri, Fabio Ciccarone, Maria Rosa Ciriolo
Veröffentlicht in: Nutrients, Ausgabe 11/8, 2019, Seite(n) 1926, ISSN 2072-6643
Herausgeber: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nu11081926

Histone H2AK119 Mono-Ubiquitination Is Essential for Polycomb-Mediated Transcriptional Repression

Autoren: Simone Tamburri, Elisa Lavarone, Daniel Fernández-Pérez, Eric Conway, Marika Zanotti, Daria Manganaro, Diego Pasini
Veröffentlicht in: Molecular Cell, Ausgabe 77/4, 2020, Seite(n) 840-856.e5, ISSN 1097-2765
Herausgeber: Cell Press
DOI: 10.1016/j.molcel.2019.11.021

Helper Innate Lymphoid Cells in Human Tumors: A Double-Edged Sword?

Autoren: Nicola Tumino, Paola Vacca, Linda Quatrini, Enrico Munari, Francesca Moretta, Andrea Pelosi, Francesca Romana Mariotti, Lorenzo Moretta
Veröffentlicht in: Frontiers in Immunology, Ausgabe 10, 2020, ISSN 1664-3224
Herausgeber: Front. Immunol.
DOI: 10.3389/fimmu.2019.03140

Keeping the Centromere under Control: A Promising Role for DNA Methylation

Autoren: Scelfo, Fachinetti
Veröffentlicht in: Cells, Ausgabe 8/8, 2019, Seite(n) 912, ISSN 2073-4409
Herausgeber: MDPI
DOI: 10.3390/cells8080912

Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition)

Autoren: Cossarizza A.; Chang H. -D.; Radbruch A.; Abrignani S.; Addo R.; Akdis M.; Andra I.; Andreata F.; Annunziato F.; Arranz E.; Bacher P.; Bari S.; Barnaba V.; Barros-Martins J.; Baumjohann D.; Beccaria C. G.; Bernardo D.; Boardman D. A.; Borger J.; Bottcher C.; Brockmann L.; Burns M.; Busch D. H.; Cameron G.; Cammarata I.; Cassotta A.; Chang Y.; Chirdo F. G.; Christakou E.; Cicin-Sain L.; Cook L.; Co
Veröffentlicht in: European Journal of Immunology, 2021, ISSN 1521-4141
Herausgeber: Wiley
DOI: 10.1002/eji.202170126

NK Cells and PMN-MDSCs in the Graft From G-CSF Mobilized Haploidentical Donors Display Distinct Gene Expression Profiles From Those of the Non-Mobilized Counterpart

Autoren: Andrea, Pelosi; Francesca, Besi; Nicola, Tumino; Pietro, Merli; Linda, Quatrini; Giuseppina, Li Pira; Mattia, Algeri; Lorenzo, Moretta; Paola, Vacca
Veröffentlicht in: Frontiers in Immunology, Ausgabe 19, 2021, ISSN 1664-3224
Herausgeber: Frontiers Media
DOI: 10.3389/fimmu.2021.657329

Human NK cells, their receptors and function

Autoren: Linda Quatrini, Mariella Della Chiesa, Simona Sivori, Maria Cristina Mingari, Daniela Pende, Lorenzo Moretta
Veröffentlicht in: Eur J Immunol ., 2021, ISSN 0014-2980
Herausgeber: John Wiley & Sons Ltd.
DOI: 10.1002/eji.202049028

The local microenvironment drives activation of neutrophils in human brain tumors

Autoren: Roeltje R Maas , Klara Soukup , Nadine Fournier , Matteo Massara , Sabine Galland , Mara Kornete , Vladimir Wischnewski , Joao Lourenco , Davide Croci , Ángel F Álvarez-Prado , Damien N Marie , Johanna Lilja , Rachel Marcone6, Gabriel F Calvo , Rui Santalla Mendez , Pauline Aubel , Leire Bejarano , Pratyaksha Wirapati , Iván Ballesteros , Andrés Hidalgo , Andreas F Hottinger , Jean-Philippe Br
Veröffentlicht in: Cell, 2023, ISSN 2073-4409
Herausgeber: MDPI AG
DOI: 10.1016/j.cell.2023.08.043

Insights Into Mechanisms of Oriented Division From Studies in 3D Cellular Models

Autoren: Federico Donà; Susanna Eli; Marina Mapelli
Veröffentlicht in: Frontiers in Cell and Developmental Biology, Ausgabe 23, 2022, ISSN 2296-634X
Herausgeber: Frontiers Media
DOI: 10.3389/fcell.2022.847801

Lipid Droplet Biosynthesis Impairment through DGAT2 Inhibition Sensitizes MCF7 Breast Cancer Cells to Radiation

Autoren: Clelia Nisticò; Clelia Nisticò; Francesca Pagliari; Emanuela Chiarella; Joana F. Guerreiro; Joana F. Guerreiro; Maria Grazia Marafioti; Maria Grazia Marafioti; Ilenia Aversa; Ilenia Aversa; Geraldine Genard; Rachel Hanley; Rachel Hanley; Daniel Garcia-Calderón; Daniel Garcia-Calderón; Heather M. Bond; Maria Mesuraca; Luca Tirinato; Luca Tirinato; Maria Francesca Spadea; Joao Seco; Joao Seco
Veröffentlicht in: International Journal of Molecular Sciences, Ausgabe 1, 2021, ISSN 1422-0067
Herausgeber: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms221810102

The Evolving Role of FGFR2 Inhibitors in Intrahepatic Cholangiocarcinoma: From Molecular Biology to Clinical Targeting.

Autoren: Salati M.; Caputo F.; Baldessari C.; Carotenuto P.; Messina M.; Caramaschi S.; Dominici M.; Bonetti L. R.
Veröffentlicht in: Cancer Management and Research, 2021, ISSN 1179-1322
Herausgeber: Dove Medical Press Ltd
DOI: 10.2147/cmar.s330710

How the Immune System Responds to Allergy Immunotherapy

Autoren: Irene Veneziani; Nadine Landolina; Biancamaria Ricci; Oliviero Rossi; Lorenzo Moretta; Enrico Maggi
Veröffentlicht in: Biomedicines, Ausgabe 1, 2022, ISSN 2227-9059
Herausgeber: MDPI
DOI: 10.3390/biomedicines10112825

Transforming the Chemical Structure and Bio-Nano Activity of Doxorubicin by Ultrasound for Selective Killing of Cancer Cells

Autoren: Sukhvir Kaur Bhangu, Soraia Fernandes, Giovanni Luca Beretta, Stella Tinelli, Marco Cassani, Agata Radziwon, Marcin Wojnilowicz, Sophia Sarpaki, Irinaios Pilatis, Nadia Zaffaroni, Giancarlo Forte, Frank Caruso, Muthupandian Ashokkumar, Francesca Cavalieri
Veröffentlicht in: Advanced Materials, 2022, ISSN 0935-9648
Herausgeber: United Nations Industrial Developement Organization
DOI: 10.1002/adma.202107964

Combining β-Carotene with 5-FU via Polymeric Nanoparticles as a Novel Therapeutic Strategy to Overcome uL3-Mediated Chemoresistance in p53-Deleted Colorectal Cancer Cells

Autoren: Carotenuto, Pietro; Pecoraro, Annalisa; Brignola, Chiara; Barbato, Anna; Franco, Brunella; Longobardi, Giuseppe; Conte, Claudia; Quaglia, Fabiana; Russo, Giulia; Russo, Annapina
Veröffentlicht in: Mol. Pharmaceutics, Ausgabe 18, 2023, ISSN 1543-8384
Herausgeber: American Chemical Society
DOI: 10.1021/acs.molpharmaceut.2c00876

JMJD6 Shapes a Pro-tumor Microenvironment via ANXA1-Dependent Macrophage Polarization in Breast Cancer

Autoren: Bianca Cioni ; Silvia Ratti ; Annamaria Piva ; Irene Tripodi ; Matteo Milani ; Francesca Menichetti ; Tiziana Langella ; Laura Botti ; Loris De Cecco ; Claudia Chiodoni ; Daniele Lecis ; Mario P. Colombo
Veröffentlicht in: Molecular Cancer Research, 2023, ISSN 1541-7786
Herausgeber: American Association for Cancer Research
DOI: 10.1158/1541-7786.mcr-22-0370

An Elegant Four-Helical Fold in NOX and STEAP Enzymes Facilitates Electron Transport across Biomembranes—Similar Vehicle, Different Destination

Autoren: Wout Oosterheert, Joana Reis, Piet Gros, Andrea Mattevi
Veröffentlicht in: Accounts of Chemical Research, Ausgabe 53, 2023, Seite(n) 1969-1980, ISSN 0001-4842
Herausgeber: American Chemical Society
DOI: 10.1021/acs.accounts.0c00400

Lipid droplets and ferritin heavy chain: a devilish liaison in human cancer cell radioresistance

Autoren: Luca Tirinato Is a corresponding authorMaria Grazia MarafiotiFrancesca Pagliari Is a corresponding authorJeannette JansenIlenia AversaRachel HanleyClelia NisticòDaniel Garcia-CalderónGeraldine GenardJoana Filipa GuerreiroFrancesco Saverio CostanzoJoao Seco
Veröffentlicht in: Cancer Biology, 2021, ISSN 2079-7737
Herausgeber: eLife Sciences Publications
DOI: 10.7554/elife.72943

Whole-genome CRISPR screening identifies PI3K/AKT as a downstream component of the oncogenic GNAQ–focal adhesion kinase signaling circuitry

Autoren: Nadia Arang, Simone Lubrano, Damiano Cosimo Rigiracciolo, Daniela Nachmanson, Scott M. Lippman, Prashant Mali, Olivier Harismendy, J. Silvio Gutkind
Veröffentlicht in: J Biol Chem, 2023, ISSN 0021-9258
Herausgeber: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1016/j.jbc.2022.102866

Tumor in 3D: In Vitro Complex Cellular Models to Improve Nanodrugs Cancer Therapy

Autoren: Soraia Fernandes, Marco Cassani, Stefania Pagliari, Petr Filipensky, Francesca Cavalieri, Giancarlo Forte
Veröffentlicht in: Current Medicinal Chemistry, Ausgabe 27, 2021, Seite(n) 7234-7255, ISSN 0929-8673
Herausgeber: Bentham Science Publishers
DOI: 10.2174/0929867327666200625151134

NK cells and ILCs in tumor immunotherapy

Autoren: Simona Sivori , Daniela Pende , Linda Quatrini , Gabriella Pietra, Mariella Della Chiesa , Paola Vacca , Nicola Tumino , Francesca Moretta , Maria Cristina Mingari , Franco Locatelli , Lorenzo Moretta
Veröffentlicht in: Molecular Aspects of Medicine, 2021, ISSN 0098-2997
Herausgeber: Pergamon Press Ltd.
DOI: 10.1016/j.mam.2020.100870

Cilia and Cancer: From Molecular Genetics to Therapeutic Strategies

Autoren: Pietro Carotenuto; Sergio A. Gradilone; Brunella Franco
Veröffentlicht in: Genes, Ausgabe 50, 2023, ISSN 2073-4425
Herausgeber: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/genes14071428

Interferon signaling promotes tolerance to chromosomal instability during metastatic evolution in renal cancer

Autoren: Luigi Perelli, Federica Carbone, Li Zhang, Justin K. Huang, Courtney Le, Hania Khan, Francesca Citron, Edoardo Del Poggetto, Tony Gutschner, Hideo Tomihara, Melinda Soeung, Rosalba Minelli, Sanjana Srinivasan, Michael Peoples, Truong Nguyen Anh Lam, Sebastian Lundgren, Ruohan Xia, Cihui Zhu, Alaa M. T. Mohamed, Jianhua Zhang, Kanishka Sircar, Alessandro Sgambato, JianJun Gao, Eric Jonasch, Giulio
Veröffentlicht in: Nature Cancer, 2023, ISSN 2662-1347
Herausgeber: Nature Portfolio
DOI: 10.1038/s43018-023-00584-1

Regulation of the Immune System Development by Glucocorticoids and Sex Hormones.

Autoren: Quatrini L.; Ricci B.; Ciancaglini C.; Tumino N.; Moretta L.
Veröffentlicht in: Frontiers in Immunology, Ausgabe 9, 2021, ISSN 1664-3224
Herausgeber: Frontiers Media
DOI: 10.3389/fimmu.2021.672853

Synthetic Lethal Screens Reveal Cotargeting FAK and MEK as a Multimodal Precision Therapy for GNAQ-Driven Uveal Melanoma

Autoren: Justine S. Paradis; Monica Acosta ; Robert Saddawi-Konefka ; Ayush Kishore; Simone Lubrano ; Frederico Gomes ; Nadia Arang; Manoela Tiago; Silvia Coma; Xingyu Wu; Kyle Ford; Chi-Ping Day ; Glenn Merlino; Prashant Mali; Jonathan A. Pachter ; Takami Sato ; Andrew E. Aplin ; J. Silvio Gutkind
Veröffentlicht in: Clin Cancer Res, 2021, ISSN 1078-0432
Herausgeber: American Association for Cancer Research
DOI: 10.1158/1078-0432.ccr-20-3363

Identification of a Kupffer cell subset capable of reverting the T cell dysfunction induced by hepatocellular priming

Autoren: Giorgia De Simone , Francesco Andreata , Camille Bleriot , Valeria Fumagalli , Chiara Laura , José M Garcia-Manteiga , Pietro Di Lucia , Stefano Gilotto , Xenia Ficht , Federico F De Ponti , Elisa B Bono , Leonardo Giustini , Gioia Ambrosi , Marta Mainetti , Paola Zordan , Alexandre P Bénéchet , Micol Ravà , Svetoslav Chakarov , Federica Moalli , Marc Bajenoff , Luca G Guidotti , Florent Ginho
Veröffentlicht in: Immunity, 2021, ISSN 1074-7613
Herausgeber: Cell Press
DOI: 10.1016/j.immuni.2021.05.005

High-throughput chemogenetic drug screening reveals PKC-RhoA/PKN as a targetable signaling vulnerability in GNAQ-driven uveal melanoma

Autoren: Nadia Arang , Simone Lubrano , Michele Ceribelli , Damiano C Rigiracciolo , Robert Saddawi-Konefka , Farhoud Faraji , Sydney I Ramirez , Daehwan Kim , Frances A Tosto , Erica Stevenson , Yuan Zhou , Zhiyong Wang , Julius Bogomolovas , Alfredo A Molinolo , Danielle L Swaney , Nevan J Krogan , Jing Yang , Silvia Coma , Jonathan A Pachter , Andrew E Aplin , Dario R Alessi , Craig J Thomas , J Silvio
Veröffentlicht in: Cell Reports Medicine, 2023, ISSN 2666-3791
Herausgeber: New York: Cell Pres Elsevier Inc.
DOI: 10.1016/j.xcrm.2023.101244

Inhibitory Receptors and Checkpoints in Human NK Cells, Implications for the Immunotherapy of Cancer.

Autoren: Simona Sivori; Mariella Della Chiesa; Simona Carlomagno; Linda Quatrini; Enrico Munari; Paola Vacca; Nicola Tumino; Francesca Romana Mariotti; Maria Cristina Mingari; Maria Cristina Mingari; Daniela Pende; Lorenzo Moretta
Veröffentlicht in: Frontiers Media S.A, 2020, ISSN 1664-3224
Herausgeber: Frontiers Media S.A
DOI: 10.3389/fimmu.2020.02156

Glucocorticoids inhibit human hematopoietic stem cell differentiation toward a common ILC precursor

Autoren: Linda Quatrini, PhD Nicola Tumino, PhD Francesca Besi, MSc Cecilia Ciancaglini, MSc Federica Galaverna, MD, PhD Antonio Giacomo Grasso, MD Pietro Merli, MD Franco Locatelli, MD, PhD Paola Vacca, PhD Lorenzo Moretta, MD
Veröffentlicht in: J Allergy Clin Immunol ., 2022, ISSN 2213-2198
Herausgeber: Elsevier
DOI: 10.1016/j.jaci.2021.10.012

Human Cancer Cell Radiation Response Investigated through Topological Analysis of 2D Cell Networks

Autoren: Luca Tirinato, Valentina Onesto, Daniel Garcia-Calderon, Francesca Pagliari, Maria-Francesca Spadea, Joao Seco & Francesco Gentile
Veröffentlicht in: Annals of Biomedical Engineering, 2023, ISSN 0090-6964
Herausgeber: Kluwer Academic Publishers
DOI: 10.1007/s10439-023-03215-z

Genome-Wide Mapping and Microscopy Visualization of Protein–DNA Interactions by pA-DamID

Autoren: Tom van Schaik, Stefano G. Manzo & Bas van Steensel
Veröffentlicht in: Methods Mol Biol ., 2022, ISSN 1064-3745
Herausgeber: Humana Press, Inc.
DOI: 10.1007/978-1-0716-2140-0_12

A non-dividing cell population with high pyruvate dehydrogenase kinase activity regulates metabolic heterogeneity and tumorigenesis in the intestine

Autoren: Carlos Sebastian; Christina Ferrer; Maria Serra; Jee-Eun Choi; Nadia Ducano; Alessia Mira; Manasvi S. Shah; Sylwia A. Stopka; Andrew J. Perciaccante; Claudio Isella; Daniel Moya-Rull; Marianela Vara-Messler; Silvia Giordano; Elena Maldi; Niyati Desai; Diane E. Capen; Enzo Medico; Murat Cetinbas; Ruslan I. Sadreyev; Dennis Brown; Miguel N. Rivera; Anna Sapino; David T. Breault; Nathalie Y. R. Agar;
Veröffentlicht in: Nature Communications, Ausgabe 64, 2022, ISSN 2041-1723
Herausgeber: Nature Publishing Group
DOI: 10.1038/s41467-022-29085-y

Autophagy and longevity: Evolutionary hints from hyper-longevous mammals

Autoren: Andrea G. Locatelli, Simone Cenc
Veröffentlicht in: Front. Endocrinol, 2022, ISSN 1664-2392
Herausgeber: Frontiers Media
DOI: 10.3389/fendo.2022.1085522

Single-cell imaging and transcriptomic analyses of firm adhesion between patient-derived cancer and endothelial cells under shear stress

Autoren: Camilla Cerutti; Lucilla Luzi; Giulia De Michele; Valentina Gambino; Enrica Migliaccio; Pier Giuseppe Pelicci
Veröffentlicht in: Proc Natl Acad Sci U S A ., Ausgabe 26, 2024, ISSN 0027-8424
Herausgeber: National Academy of Sciences
DOI: 10.12688/openreseurope.15989.1

Raman Spectroscopic Stratification of Multiple Myeloma Patients Based on Exosome Profiling.

Autoren: Mario Vincenzo Russo; Luca Tirinato; Francesca Scionti; Maria Laura Coluccio; Gerardo Perozziello; Caterina Riillo; Vincenzo Mollace; Santo Gratteri; Natalia Malara; Maria Teresa Di Martino; Giuseppe Viglietto; Pierosandro Tagliaferri; Pierfrancesco Tassone; Marco Rossi; Patrizio Candeloro
Veröffentlicht in: ACS Omega, 2020, ISSN 2470-1343
Herausgeber: ACS
DOI: 10.1021/acsomega.0c03813

PSGL-1 decorated with sialyl Lewisa/x promotes high affinity binding of myeloma cells to P-selectin but is dispensable for E-selectin engagement

Autoren: Michael O’Dwyer, Lucy Kirkham-McCarthy, Marina Cerreto, Robin Foà & Alessandro Natoni
Veröffentlicht in: Scientific Reports, 2024, ISSN 2045-2322
Herausgeber: Nature Publishing Group
DOI: 10.1038/s41598-024-52212-2

Suche nach OpenAIRE-Daten ...

International Cancer Research Fellowships - 2

Leistungen

Veröffentlichungen

Diese Seite teilen Diese Seite in sozialen Netzwerken teilen

Herunterladen Den Inhalt der Seite herunterladen