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T cell-driven inflammatory mechanisms promote recovery after acute brain injury

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies (opens in new window)

Author(s): Steffanie Heindl, Alessio Ricci, Olga Carofiglio, Qihui Zhou, Thomas Arzberger, Nikolett Lenart, Nicolai Franzmeier, Tibor Hortobagyi, Peter T. Nelson, Ann M. Stowe, Adam Denes, Dieter Edbauer, Arthur Liesz
Published in: Journal of Experimental Medicine, Issue 218/8, 2021, ISSN 0022-1007
Publisher: Rockefeller University Press
DOI: 10.1084/jem.20202411

Microbiota-derived short chain fatty acids modulate microglia and promote Aβ plaque deposition (opens in new window)

Author(s): Alessio Vittorio Colombo, Rebecca Katie Sadler, Gemma Llovera, Vikramjeet Singh, Stefan Roth, Steffanie Heindl, Laura Sebastian Monasor, Aswin Verhoeven, Finn Peters, Samira Parhizkar, Frits Kamp, Mercedes Gomez de Aguero, Andrew J MacPherson, Edith Winkler, Jochen Herms, Corinne Benakis, Martin Dichgans, Harald Steiner, Martin Giera, Christian Haass, Sabina Tahirovic, Arthur Liesz
Published in: eLife, Issue 10, 2021, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.59826

Post-injury immunosuppression and secondary infections are caused by an AIM2 inflammasome-driven signaling cascade (opens in new window)

Author(s): Stefan Roth, Jiayu Cao, Vikramjeet Singh, Steffen Tiedt, Gabriel Hundeshagen, Ting Li, Julia D. Boehme, Dhruv Chauhan, Jie Zhu, Alessio Ricci, Oliver Gorka, Yaw Asare, Jun Yang, Mary S. Lopez, Markus Rehberg, Dunja Bruder, Shengxiang Zhang, Olaf Groß, Martin Dichgans, Veit Hornung, Arthur Liesz
Published in: Immunity, Issue 54/4, 2021, Page(s) 648-659.e8, ISSN 1074-7613
Publisher: Cell Press
DOI: 10.1016/j.immuni.2021.02.004

DNA-sensing inflammasomes cause recurrent atherosclerotic stroke

Author(s): "Jiayu Cao1*, Stefan Roth1*#, Sijia Zhang1, Anna Kopczak1,2, Samira Mami1, Yaw Asare1, Marios K. Georgakis1,2,3, Denise Messerer4, Amit Horn5, Ruth Shemer5, Charlene Jaqcmarcq6, Audrey Picot6, Jack P. Green7, Christina Schlegl1, Xinghai Li8, Lukas Tomas4, Alexander Dutsch8, Thomas G Liman9, Matthias Endres9,10,11,12, Saskia Rita Wernsdorf1, Christina Fürle1, Olga Carofiglio1, Jie Zhu1, David Broug"
Published in: NATURE, 2024, ISSN 0028-0836
Publisher: Nature Publishing Group

The microbiome-gut-brain axis in acute and chronic brain diseases (opens in new window)

Author(s): Corinne Benakis, Camille Martin-Gallausiaux, Jean-Pierre Trezzi, Philip Melton, Arthur Liesz, Paul Wilmes
Published in: Current Opinion in Neurobiology, Issue 61, 2020, Page(s) 1-9, ISSN 0959-4388
Publisher: Elsevier BV
DOI: 10.1016/j.conb.2019.11.009

Innate immune memory after brain injury drives inflammatory cardiac dysfunction

Author(s): Alba Simats1,2,22, Sijia Zhang1,22, Denise Messerer3, Faye Chong4, Sude Beşkardeş4, Aparna Sharma Chivukula3, Jiayu Cao1, Simon Besson-Girard1, Felipe A. Montellano7,13, Caroline Morbach8, Olga Carofiglio1, Alessio Ricci1, Stefan Roth1, Gemma Llovera1, Rashween Singh1, Yiming Chen1, Severin Filser1, Nikolaus Plesnila1,9, Christian Braun10, Hannah Spitzer1, Ozgun Gokce1,11, Martin Dichgans1,9,11,
Published in: CELL, 2024, ISSN 0092-8674
Publisher: Cell Press

Short-Chain Fatty Acids Improve Poststroke Recovery via Immunological Mechanisms (opens in new window)

Author(s): Rebecca Sadler, Julia V. Cramer, Steffanie Heindl, Sarantos Kostidis, Dene Betz, Kielen R. Zuurbier, Bernd H. Northoff, Marieke Heijink, Mark P. Goldberg, Erik J. Plautz, Stefan Roth, Rainer Malik, Martin Dichgans, Lesca M. Holdt, Corinne Benakis, Martin Giera, Ann M. Stowe, Arthur Liesz
Published in: The Journal of Neuroscience, Issue 40/5, 2020, Page(s) 1162-1173, ISSN 0270-6474
Publisher: Society for Neuroscience
DOI: 10.1523/jneurosci.1359-19.2019

Microglia monitor and protect neuronal function through specialized somatic purinergic junctions (opens in new window)

Author(s): Csaba Cserép, Balázs Pósfai, Nikolett Lénárt, Rebeka Fekete, Zsófia I. László, Zsolt Lele, Barbara Orsolits, Gábor Molnár, Steffanie Heindl, Anett D. Schwarcz, Katinka Ujvári, Zsuzsanna Környei, Krisztina Tóth, Eszter Szabadits, Beáta Sperlágh, Mária Baranyi, László Csiba, Tibor Hortobágyi, Zsófia Maglóczky, Bernadett Martinecz, Gábor Szabó, Ferenc Erdélyi, Róbert Szipőcs
Published in: Science, Issue 367/6477, 2020, Page(s) 528-537, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.aax6752

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