T cell-driven inflammatory mechanisms promote recovery after acute brain injury

Pubblicazioni

Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies

Autori: Steffanie Heindl, Alessio Ricci, Olga Carofiglio, Qihui Zhou, Thomas Arzberger, Nikolett Lenart, Nicolai Franzmeier, Tibor Hortobagyi, Peter T. Nelson, Ann M. Stowe, Adam Denes, Dieter Edbauer, Arthur Liesz
Pubblicato in: Journal of Experimental Medicine, Numero 218/8, 2021, ISSN 0022-1007
Editore: Rockefeller University Press
DOI: 10.1084/jem.20202411

Microbiota-derived short chain fatty acids modulate microglia and promote Aβ plaque deposition

Autori: Alessio Vittorio Colombo, Rebecca Katie Sadler, Gemma Llovera, Vikramjeet Singh, Stefan Roth, Steffanie Heindl, Laura Sebastian Monasor, Aswin Verhoeven, Finn Peters, Samira Parhizkar, Frits Kamp, Mercedes Gomez de Aguero, Andrew J MacPherson, Edith Winkler, Jochen Herms, Corinne Benakis, Martin Dichgans, Harald Steiner, Martin Giera, Christian Haass, Sabina Tahirovic, Arthur Liesz
Pubblicato in: eLife, Numero 10, 2021, ISSN 2050-084X
Editore: eLife Sciences Publications
DOI: 10.7554/elife.59826

Post-injury immunosuppression and secondary infections are caused by an AIM2 inflammasome-driven signaling cascade

Autori: Stefan Roth, Jiayu Cao, Vikramjeet Singh, Steffen Tiedt, Gabriel Hundeshagen, Ting Li, Julia D. Boehme, Dhruv Chauhan, Jie Zhu, Alessio Ricci, Oliver Gorka, Yaw Asare, Jun Yang, Mary S. Lopez, Markus Rehberg, Dunja Bruder, Shengxiang Zhang, Olaf Groß, Martin Dichgans, Veit Hornung, Arthur Liesz
Pubblicato in: Immunity, Numero 54/4, 2021, Pagina/e 648-659.e8, ISSN 1074-7613
Editore: Cell Press
DOI: 10.1016/j.immuni.2021.02.004

The microbiome-gut-brain axis in acute and chronic brain diseases

Autori: Corinne Benakis, Camille Martin-Gallausiaux, Jean-Pierre Trezzi, Philip Melton, Arthur Liesz, Paul Wilmes
Pubblicato in: Current Opinion in Neurobiology, Numero 61, 2020, Pagina/e 1-9, ISSN 0959-4388
Editore: Elsevier BV
DOI: 10.1016/j.conb.2019.11.009

Short-Chain Fatty Acids Improve Poststroke Recovery via Immunological Mechanisms

Autori: Rebecca Sadler, Julia V. Cramer, Steffanie Heindl, Sarantos Kostidis, Dene Betz, Kielen R. Zuurbier, Bernd H. Northoff, Marieke Heijink, Mark P. Goldberg, Erik J. Plautz, Stefan Roth, Rainer Malik, Martin Dichgans, Lesca M. Holdt, Corinne Benakis, Martin Giera, Ann M. Stowe, Arthur Liesz
Pubblicato in: The Journal of Neuroscience, Numero 40/5, 2020, Pagina/e 1162-1173, ISSN 0270-6474
Editore: Society for Neuroscience
DOI: 10.1523/jneurosci.1359-19.2019

Microglia monitor and protect neuronal function through specialized somatic purinergic junctions

Autori: Csaba Cserép, Balázs Pósfai, Nikolett Lénárt, Rebeka Fekete, Zsófia I. László, Zsolt Lele, Barbara Orsolits, Gábor Molnár, Steffanie Heindl, Anett D. Schwarcz, Katinka Ujvári, Zsuzsanna Környei, Krisztina Tóth, Eszter Szabadits, Beáta Sperlágh, Mária Baranyi, László Csiba, Tibor Hortobágyi, Zsófia Maglóczky, Bernadett Martinecz, Gábor Szabó, Ferenc Erdélyi, Róbert Szipőcs
Pubblicato in: Science, Numero 367/6477, 2020, Pagina/e 528-537, ISSN 0036-8075
Editore: American Association for the Advancement of Science
DOI: 10.1126/science.aax6752

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