Integration and adaptation of impaired mitochondrial fitness in orchestrating T cell dysfunction in the tumor microenvironment

Publicaciones

CD36-mediated metabolic adaptation supports regulatory T cell survival and function in tumors

Autores: Haiping Wang, Fabien Franco, Yao-Chen Tsui, Xin Xie, Marcel P. Trefny, Roberta Zappasodi, Syed Raza Mohmood, Juan Fernández-García, Chin-Hsien Tsai, Isabell Schulze, Florence Picard, Etienne Meylan, Roy Silverstein, Ira Goldberg, Sarah-Maria Fendt, Jedd D. Wolchok, Taha Merghoub, Camilla Jandus, Alfred Zippelius, Ping-Chih Ho
Publicado en: Nature Immunology, Edición 21/3, 2020, Página(s) 298-308, ISSN 1529-2908
Editor: Nature Publishing Group
DOI: 10.1038/s41590-019-0589-5

CTLA-4 blockade drives loss of Treg stability in glycolysis-low tumours

Autores: Roberta Zappasodi, Inna Serganova, Ivan J. Cohen, Masatomo Maeda, Masahiro Shindo, Yasin Senbabaoglu, McLane J. Watson, Avigdor Leftin, Rachana Maniyar, Svena Verma, Matthew Lubin, Myat Ko, Mayuresh M. Mane, Hong Zhong, Cailian Liu, Arnab Ghosh, Mohsen Abu-Akeel, Ellen Ackerstaff, Jason A. Koutcher, Ping-Chih Ho, Greg M. Delgoffe, Ronald Blasberg, Jedd D. Wolchok, Taha Merghoub
Publicado en: Nature, Edición 591/7851, 2021, Página(s) 652-658, ISSN 0028-0836
Editor: Nature Publishing Group
DOI: 10.1038/s41586-021-03326-4

Disturbed mitochondrial dynamics in CD8+ TILs reinforce T cell exhaustion

Autores: Yi-Ru Yu, Hana Imrichova, Haiping Wang, Tung Chao, Zhengtao Xiao, Min Gao, Marcela Rincon-Restrepo, Fabien Franco, Raphael Genolet, Wan-Chen Cheng, Camilla Jandus, George Coukos, Yi-Fan Jiang, Jason W. Locasale, Alfred Zippelius, Pu-Ste Liu, Li Tang, Christoph Bock, Nicola Vannini, Ping-Chih Ho
Publicado en: Nature Immunology, Edición 21/12, 2020, Página(s) 1540-1551, ISSN 1529-2908
Editor: Nature Publishing Group
DOI: 10.1038/s41590-020-0793-3

Metabolic programming in dendritic cells tailors immune responses and homeostasis

Autores: Sofie Hedlund Møller, Limei Wang, Ping-Chih Ho
Publicado en: Cellular & Molecular Immunology, 2021, ISSN 1672-7681
Editor: Nature Publishing Group
DOI: 10.1038/s41423-021-00753-1

Lactate modulation of immune responses in inflammatory versus tumour microenvironments

Autores: Michelangelo Certo, Chin-Hsien Tsai, Valentina Pucino, Ping-Chih Ho, Claudio Mauro
Publicado en: Nature Reviews Immunology, Edición 21/3, 2021, Página(s) 151-161, ISSN 1474-1733
Editor: Nature Publishing Group
DOI: 10.1038/s41577-020-0406-2

Metabolic adaptation orchestrates tissue context‐dependent behavior in regulatory T cells

Autores: Haiping Wang, Chun‐Hao Lu, Ping‐Chih Ho
Publicado en: Immunological Reviews, Edición 295/1, 2020, Página(s) 126-139, ISSN 0105-2896
Editor: Blackwell Publishing Inc.
DOI: 10.1111/imr.12844

Macrophage-derived glutamine boosts satellite cells and muscle regeneration

Autores: Min Shang, Federica Cappellesso, Ricardo Amorim, Jens Serneels, Federico Virga, Guy Eelen, Stefania Carobbio, Melvin Y. Rincon, Pierre Maechler, Katrien De Bock, Ping-Chih Ho, Marco Sandri, Bart Ghesquière, Peter Carmeliet, Mario Di Matteo, Emanuele Berardi, Massimiliano Mazzone
Publicado en: Nature, Edición 587/7835, 2020, Página(s) 626-631, ISSN 0028-0836
Editor: Nature Publishing Group
DOI: 10.1038/s41586-020-2857-9

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