Non-Equilibrium Protein Assembly: from Building Blocks to Biological Machines

Información del proyecto

NEPA

Identificador del acuerdo de subvención: 802960

DOI

10.3030/802960

Proyecto cerrado

Fecha de la firma de la CE 5 Noviembre 2018

Fecha de inicio 1 Octubre 2019

Fecha de finalización 30 Septiembre 2025

Financiado con arreglo a

• EXCELLENT SCIENCE - European Research Council (ERC)

Coste total

€ 1 424 574,00

Aportación de la UE

€ 1 424 574,00

Coordinado por

INSTITUTE OF SCIENCE AND TECHNOLOGY AUSTRIA
Austria

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Publicaciones

Peer reviewed articles (24)

PLCγ1 promotes phase separation of T cell signaling components

Autores: Longhui Zeng, Ivan Palaia, Anđela Šarić, Xiaolei Su
Publicado en: Journal of Cell Biology, Edición 220/6, 2021, ISSN 0021-9525
Editor: Rockefeller University Press
DOI: 10.1083/jcb.202009154

Controlling cluster size in 2D phase-separating binary mixtures with specific interactions

Autores: Palaia I, Šarić A.
Publicado en: The Journal of Chemical Physics. 156(19), 194902, 2022, ISSN 1089-7690
Editor: American Institute of Physics
DOI: 10.1063/5.0087769

Mechanochemical rules for shape-shifting filaments that remodel membranes

Autores: Meadowcroft B, Palaia I, Pfitzner AK, Roux A, Baum B, Šarić A
Publicado en: Physical Review Letters, Edición vol. 129, no. 26, 2022, ISSN 0031-9007
Editor: American Physical Society
DOI: 10.1103/physrevlett.129.268101

The proteasome controls ESCRT-III–mediated cell division in an archaeon

Autores: Gabriel Tarrason Risa, Fredrik Hurtig, Sian Bray, Anne E. Hafner, Lena Harker-Kirschneck, Peter Faull, Colin Davis, Dimitra Papatziamou, Delyan R. Mutavchiev, Catherine Fan, Leticia Meneguello, Andre Arashiro Pulschen, Gautam Dey, Siân Culley, Mairi Kilkenny, Diorge P. Souza, Luca Pellegrini, Robertus A. M. de Bruin, Ricardo Henriques, Ambrosius P. Snijders, Anđela Šarić, Ann-Christin Lindås,
Publicado en: Science, Edición 369/6504, 2020, Página(s) eaaz2532, ISSN 0036-8075
Editor: American Association for the Advancement of Science
DOI: 10.1126/science.aaz2532

An ESCRT-III Polymerization Sequence Drives Membrane Deformation and Fission

Autores: Anna-Katharina Pfitzner, Vincent Mercier, Xiuyun Jiang, Joachim Moser von Filseck, Buzz Baum, Anđela Šarić, Aurélien Roux
Publicado en: Cell, Edición 182/5, 2020, Página(s) 1140-1155.e18, ISSN 0092-8674
Editor: Cell Press
DOI: 10.1016/j.cell.2020.07.021

In Operando Imaging Electrostatic-Driven Disassembly and Reassembly of Collagen Nanostructures

Autores: Clara Garcia-Sacristan, Victor G. Gisbert, Kevin Klein, Anđela Šarić, Ricardo Garcia
Publicado en: ACS Nano, Edición 18, 2024, Página(s) 18485-18492, ISSN 1936-0851
Editor: American Chemical Society
DOI: 10.1021/acsnano.4c03839

A liquid-like coat mediates chromosome clustering during mitotic exit

Autores: Alberto Hernandez-Armendariz, Valerio Sorichetti, Yuki Hayashi, Zuzana Koskova, Andreas Brunner, Jan Ellenberg, Anđela Šarić, Sara Cuylen-Haering
Publicado en: Molecular Cell, Edición 84, 2024, Página(s) 3254-3270.e9, ISSN 1097-2765
Editor: Cell Press
DOI: 10.1016/j.molcel.2024.07.022

Exploring the Design Rules for Efficient Membrane-Reshaping Nanostructures

Autores: Joel C. Forster, Johannes Krausser, Manish R. Vuyyuru, Buzz Baum, Anđela Šarić
Publicado en: Physical Review Letters, Edición 125/22, 2020, ISSN 0031-9007
Editor: American Physical Society
DOI: 10.1103/physrevlett.125.228101

Influence of membrane-cortex linkers on the extrusion of membrane tubes

Autores: Alexandru Paraschiv, Thibaut J. Lagny, Christian Vanhille Campos, Evelyne Coudrier, Patricia Bassereau, Anđela Šarić
Publicado en: Biophysical Journal, Edición 120/4, 2021, Página(s) 598-606, ISSN 0006-3495
Editor: Biophysical Society
DOI: 10.1016/j.bpj.2020.12.028

Unconventional colloidal aggregation in chiral bacterial baths

Autores: Daniel Grober, Ivan Palaia, Mehmet Can Uçar, Edouard Hannezo, Anđela Šarić, Jérémie Palacci
Publicado en: Nature Physics, Edición 19, 2023, Página(s) 1680-1688, ISSN 1745-2473
Editor: Nature Publishing Group
DOI: 10.1038/s41567-023-02136-x

Physical mechanisms of ESCRT-III-driven cell division

Autores: Harker-Kirschneck L, Hafner AE, Yao T, Pulschen A, Vanhille-Campos C, Jiang X, Puschen A, Hurtig F, Hryniuk D, Culley S, Henriques R, Baum B, Šarić A.
Publicado en: Proceedings of the National Academy of Sciences, Edición Vol. 119, 2022, ISSN 1091-6490
Editor: National Academy of Sciences
DOI: 10.1073/pnas.2107763119

Stress granules plug and stabilize damaged endolysosomal membranes

Autores: Claudio Bussi, Agustín Mangiarotti, Christian Vanhille-Campos, Beren Aylan, Enrica Pellegrino, Natalia Athanasiadi, Antony Fearns, Angela Rodgers, Titus M. Franzmann, Anđela Šarić, Rumiana Dimova, Maximiliano G. Gutierrez
Publicado en: Nature, Edición 623, 2023, Página(s) 1062-1069, ISSN 0028-0836
Editor: Nature Publishing Group
DOI: 10.1038/s41586-023-06726-w

Elucidating the role of water in collagen self-assembly by isotopically modulating collagen hydration

Autores: Giulia Giubertoni, Liru Feng, Kevin Klein, Guido Giannetti, Luco Rutten, Yeji Choi, Anouk van der Net, Gerard Castro-Linares, Federico Caporaletti, Dimitra Micha, Johannes Hunger, Antoine Deblais, Daniel Bonn, Nico Sommerdijk, Andela Šarić, Ioana M. Ilie, Gijsje H. Koenderink, Sander Woutersen
Publicado en: Proceedings of the National Academy of Sciences, Edición 121, 2024, ISSN 0027-8424
Editor: National Academy of Sciences
DOI: 10.1073/pnas.2313162121

Dynamic Clustering Regulates Activity of Mechanosensitive Membrane Channels

Autores: Alexandru Paraschiv, Smitha Hegde, Raman Ganti, Teuta Pilizota, Anđela Šarić
Publicado en: Physical Review Letters, Edición 124/4, 2020, ISSN 0031-9007
Editor: American Physical Society
DOI: 10.1103/physrevlett.124.048102

Wrapping pathways of anisotropic dumbbell particles by Giant Unilamellar Vesicles

Autores: Azadbakht A, Meadowcroft B, Varkevisser T, Šarić A, Kraft DJ
Publicado en: Nano Letters, Edición 23(10), 2023, Página(s) 4267–4273, ISSN 1530-6984
Editor: American Chemical Society
DOI: 10.1021/acs.nanolett.3c00375

Self-replication of A <i>β</i> ₄₂ aggregates occurs on small and isolated fibril sites

Autores: Samo Curk, Johannes Krausser, Georg Meisl, Daan Frenkel, Sara Linse, Thomas C. T. Michaels, Tuomas P. J. Knowles, Anđela Šarić
Publicado en: Proceedings of the National Academy of Sciences, Edición 121, 2024, ISSN 0027-8424
Editor: National Academy of Sciences
DOI: 10.1073/pnas.2220075121

Nonadditivity in interactions between three membrane-wrapped colloidal spheres

Autores: Ali Azadbakht, Billie Meadowcroft, Juraj Májek, Anđela Šarić, Daniela J. Kraft
Publicado en: Biophysical Journal, Edición 123, 2024, Página(s) 307-316, ISSN 0006-3495
Editor: Biophysical Society
DOI: 10.1016/j.bpj.2023.12.020

Modelling membrane reshaping by staged polymerization of ESCRT-III filaments

Autores: Jiang X, Harker-Kirschneck L, Vanhille-Campos CE, Pfitzner A-K, Lominadze E, Roux A, Baum B, Šarić A
Publicado en: PLOS Computational Biology, Edición vol. 18, no. 10, 2022, Página(s) e1010586, ISSN 1553-7358
Editor: Public Library of Science
DOI: 10.1371/journal.pcbi.1010586

Durotaxis of passive nanoparticles on elastic membranes

Autores: Ivan Palaia; Alexandru Paraschiv; Vincent E. Debets; Cornelis Storm; Anđela Šarić
Publicado en: ACS Nano, 15(10), 15794 - 15802. American Chemical Society, Edición 1, 2021, ISSN 1936-086X
Editor: American Chemical Society
DOI: 10.1101/2021.04.01.438065

The patterned assembly and stepwise Vps4-mediated disassembly of composite ESCRT-III polymers drives archaeal cell division

Autores: Hurtig F, Burgers TCQ, Cezanne A, Jiang X, Mol FN, Traparić J, Pulschen AA, Nierhaus T, Tarrason-Risa G, Harker-Kirschneck L, Löwe J, Šarić A, Vlijm R, Baum B
Publicado en: Science Advances, Edición 9(11), 2023, ISSN 2375-2548
Editor: American Association for the Advancement of Science
DOI: 10.1126/sciadv.ade5224

Modelling the dynamics of vesicle reshaping and scission under osmotic shocks

Autores: Christian Vanhille-Campos, Anđela Šarić
Publicado en: Soft Matter, Edición 17/14, 2021, Página(s) 3798-3806, ISSN 1744-683X
Editor: Royal Society of Chemistry
DOI: 10.1039/d0sm02012e

Steering self-organisation through confinement

Autores: Araújo NAM, Janssen LMC, Barois T, Boffetta G, Cohen I, Corbetta A, Dauchot O, Dijkstra M, Durham WM, Dussutour A, Garnier S, Gelderblom H, Golestanian R, Isa L, Koenderink GH, Löwen H, Metzler R, Polin M, Royall CP, Šarić A, Sengupta A, Sykes C, Trianni V, Tuval I, Vogel N, Yeomans JM, Zuriguel I, Marin A, Volpe G
Publicado en: Soft Matter, Edición 19, 2023, Página(s) 1695-1704, ISSN 1744-683X
Editor: Royal Society of Chemistry
DOI: 10.1039/d2sm01562e

Self-organization of mortal filaments and its role in bacterial division ring formation

Autores: Christian Vanhille-Campos, Kevin D. Whitley, Philipp Radler, Martin Loose, Séamus Holden, Anđela Šarić
Publicado en: Nature Physics, Edición 20, 2024, Página(s) 1670-1678, ISSN 1745-2473
Editor: Nature Publishing Group
DOI: 10.1038/s41567-024-02597-8

Endosomal membrane budding patterns in plants

Autores: Ethan Weiner, Elizabeth Berryman, Felix Frey, Ariadna González Solís, André Leier, Tatiana Marquez Lago, Anđela Šarić, Marisa S. Otegui
Publicado en: Proceedings of the National Academy of Sciences, Edición 121, 2024, ISSN 0027-8424
Editor: National Academy of Sciences
DOI: 10.1073/pnas.2409407121