Mechanism and functional impact of ultra-long 3’ UTRs in the Drosophila nervous system

Project Information

Neuro-UTR

Grant agreement ID: 803258

DOI

10.3030/803258

Project closed

EC signature date 30 October 2018

Start date 1 January 2019

End date 31 December 2024

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 497 500,00

EU contribution

€ 1 497 500,00

Coordinated by

MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (8)

(Alternative) transcription start sites as regulators of RNA processing

Author(s): Carlos Alfonso-Gonzalez, Valérie Hilgers
Published in: Trends in Cell Biology, Issue 34, 2024, Page(s) 1018-1028, ISSN 0962-8924
Publisher: Elsevier BV
DOI: 10.1016/j.tcb.2024.02.010

Regulation of neuronal RNA signatures by ELAV/Hu proteins

Author(s): Valérie Hilgers
Published in: Wiley interdisciplinary reviews : WIREs RNA, Issue 1, 2022, ISSN 1757-7004
Publisher: John Wiley and Sons Inc.
DOI: 10.1002/wrna.1733

The long noncoding RNA mimi scaffolds neuronal granules to maintain nervous system maturity

Author(s): Grzejda, D. Mach, J. Schweizer, J. A. Hummel, B. Rezansoff, A. M. Eggenhofer, F. Panhale, A. Lalioti, M. E. Cabezas Wallscheid, N. Backofen, R. Felsenberg, J. Hilgers, V.
Published in: Science Advances, 2022, ISSN 2375-2548
Publisher: AAAS
DOI: 10.1126/sciadv.abo5578

Repression of the Hox gene abd-A by ELAV-mediated Transcriptional Interference

Author(s): Javier J. Castro Alvarez; Maxime Revel; Judit Carrasco; Fabienne Cléard; Daniel Pauli; Valérie Hilgers; François Karch; Robert K. Maeda
Published in: PLoS Genetics, Issue 1, 2021, ISSN 1553-7390
Publisher: Public Library of Science
DOI: 10.1371/journal.pgen.1009843

A critical developmental window for ELAV/Hu-dependent mRNA signatures at the onset of neuronal differentiation

Author(s): Judit Carrasco; Fernando Mateos; Valérie Hilgers
Published in: Cell Reports, Issue 1, 2022, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2022.111542

Sites of transcription initiation drive mRNA isoform selection

Author(s): Alfonso-Gonzalez, Carlos; Legnini, Ivano; Holec, Sarah; Arrigoni, Laura; Ozbulut, Hasan Can; Mateos, Fernando; Koppstein, David; Rybak-Wolf, Agnieszka; Bönisch, Ulrike; Rajewsky, Nikolaus; Hilgers, Valérie
Published in: Cell, 2023, ISSN 0092-8674
Publisher: Cell Press
DOI: 10.1016/j.cell.2023.04.012

ELAV and FNE Determine Neuronal Transcript Signatures through EXon-Activated Rescue

Author(s): Judit Carrasco, Michael Rauer, Barbara Hummel, Dominika Grzejda, Carlos Alfonso-Gonzalez, Yeon Lee, Qingqing Wang, Monika Puchalska, Gerhard Mittler, Valérie Hilgers
Published in: Molecular Cell, 2020, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2020.09.011

Identification of regulatory links between transcription and RNA processing with long-read sequencing

Author(s): Carlos Alfonso-Gonzalez, Laura Arrigoni, Hasan Can Ozbulut, Stefanie Falk, Ulrike Bönisch, Valérie Hilgers
Published in: STAR Protocols, Issue 4, 2024, Page(s) 102505, ISSN 2666-1667
Publisher: Elsevier BV
DOI: 10.1016/j.xpro.2023.102505