Not all ribosomes are created equal
Mitochondria and chloroplasts are cellular organelles that play a role in the energy pathway. Mitochondria are found in both plants and animals and are the so-called powerhouses of cells, breaking down nutrients (primarily glucose) to make energy in the form of adenosine triphosphate (ATP). However, animals get their energy-rich nutrients by ingesting them, whereas plants make their glucose via photosynthesis in the plants' chloroplasts. Both mitochondria and chloroplasts likely have bacterial ancestors that developed symbiotic relationships with host cells and eventually became the organelles we know today. Both have their own machinery to make proteins including DNA and ribosomes, but we still do not know a lot about the ribosomes in mitochondria and chloroplasts. The EU-funded Orgasome project plans to get an experimental 'time-lapse' reconstruction of translation in these two organelles to get to the bottom of things.
Fields of science
Funding SchemeERC-STG - Starting Grant
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