Assessing the role of ribosomes and mRNA translation in shaping the inflammatory response

Project Information

RiboInflam

Grant agreement ID: 805500

DOI

10.3030/805500

Project closed

EC signature date 23 October 2018

Start date 1 January 2019

End date 31 December 2024

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 499 720,00

EU contribution

€ 1 499 720,00

Coordinated by

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Open Research Data Pilot (1)

Data Management Plan

Publications

Peer reviewed articles (14)

Ribosome dynamics and mRNA turnover, a complex relationship under constant cellular scrutiny

Author(s): Christelle Morris, David Cluet, Emiliano P. Ricci
Published in: WIREs RNA, 2021, ISSN 1757-7004
Publisher: John Wiley and Sons Inc.
DOI: 10.1002/wrna.1658

Translation-dependent and -independent mRNA decay occur through mutually exclusive pathways defined by ribosome density during T cell activation

Author(s): Blandine C. Mercier, Emmanuel Labaronne, David Cluet, Laura Guiguettaz, Nicolas Fontrodona, Alicia Bicknell, Antoine Corbin, Mélanie Wencker, Fabien Aube, Laurent Modolo, Karina Jouravleva, Didier Auboeuf, Melissa J. Moore, Emiliano P. Ricci
Published in: Genome Research, 2024, ISSN 1088-9051
Publisher: Cold Spring Harbor Laboratory Press
DOI: 10.1101/gr.277863.123

The DEAD box RNA helicase DDX42 is an intrinsic inhibitor of positive-strand RNA viruses

Author(s): Boris Bonaventure, Antoine Rebendenne, Ana Luiza Chaves Valadão, Mary Arnaud-Arnould, Ségolène Gracias, Francisco Garcia de Gracia, Joe McKellar, Emmanuel Labaronne, Marine Tauziet, Valérie Vivet-Boudou, Eric Bernard, Laurence Briant, Nathalie Gros, Wassila Djilli, Valérie Courgnaud, Hugues Parrinello, Stéphanie Rialle, Mickaël Blaise, Laurent Lacroix, Marc Lavigne, Jean-Christophe Paillart
Published in: EMBO Reports, 2022, ISSN 1469-3178
Publisher: EMBO Press
DOI: 10.15252/embr.202154061

The long non-coding RNA LUCAT1 is a negative feedback regulator of interferon responses in humans

Author(s): Shiuli Agarwal, Tim Vierbuchen, Sreya Ghosh, Jennie Chan, Zhaozhao Jiang, Richard K. Kandasamy, Emiliano Ricci, Katherine A. Fitzgerald
Published in: Nature Communications, Issue 11/1, 2020, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-020-20165-5

RSL24D1 sustains steady-state ribosome biogenesis and pluripotency translational programs in embryonic stem cells

Author(s): Sébastien Durand, Marion Bruelle, Fleur Bourdelais, Bigitha Bennychen, Juliana Blin-Gonthier, Caroline Isaac, Aurélia Huyghe, Sylvie Martel, Antoine Seyve, Christophe Vanbelle, Annie Adrait, Yohann Couté, David Meyronet, Frédéric Catez, Jean-Jacques Diaz, Fabrice Lavial, Emiliano P. Ricci, François Ducray, Mathieu Gabut
Published in: Nature Communications, 2023, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-023-36037-7

Mutant Huntingtin stalls ribosomes and represses protein synthesis in a cellular model of Huntington disease

Author(s): Mehdi Eshraghi, Pabalu P. Karunadharma, Juliana Blin, Neelam Shahani, Emiliano P. Ricci, Audrey Michel, Nicolai T. Urban, Nicole Galli, Manish Sharma, Uri Nimrod Ramírez-Jarquín, Katie Florescu, Jennifer Hernandez, Srinivasa Subramaniam
Published in: Nature Communications, Issue 12/1, 2021, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-21637-y

Shaping the Innate Immune Response Through Post-Transcriptional Regulation of Gene Expression Mediated by RNA-Binding Proteins

Author(s): Anissa Guillemin; Anuj Kumar; Mélanie Wencker; Mélanie Wencker; Emiliano P. Ricci
Published in: Frontiers in Immunology, Issue 10, 2022, ISSN 1664-3224
Publisher: Frontiers Media S.A.
DOI: 10.3389/fimmu.2021.796012

Metabolism-dependent secondary effect of anti-MAPK cancer therapy on DNA repair

Author(s): Fabien Aubé, Nicolas Fontrodona, Laura Guiguettaz, Elodie Vallin, Lucilla Fabbri, Audrey Lapendry, Stephan Vagner, Emiliano P Ricci, Didier Auboeuf
Published in: NAR Cancer, Issue 6, 2024, ISSN 2632-8674
Publisher: Oxford Academic
DOI: 10.1093/narcan/zcae019

System-wide Profiling of RNA-Binding Proteins Uncovers Key Regulators of Virus Infection

Author(s): Manuel Garcia-Moreno, Marko Noerenberg, Shuai Ni, Aino I. Järvelin, Esther González-Almela, Caroline E. Lenz, Marcel Bach-Pages, Victoria Cox, Rosario Avolio, Thomas Davis, Svenja Hester, Thibault J.M. Sohier, Bingnan Li, Gregory Heikel, Gracjan Michlewski, Miguel A. Sanz, Luis Carrasco, Emiliano P. Ricci, Vicent Pelechano, Ilan Davis, Bernd Fischer, Shabaz Mohammed, Alfredo Castello
Published in: Molecular Cell, Issue 74/1, 2019, Page(s) 196-211.e11, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2019.01.017

Genome editing in primary cells and in vivo using viral-derived Nanoblades loaded with Cas9-sgRNA ribonucleoproteins

Author(s): Philippe E. Mangeot, Valérie Risson, Floriane Fusil, Aline Marnef, Emilie Laurent, Juliana Blin, Virginie Mournetas, Emmanuelle Massouridès, Thibault J. M. Sohier, Antoine Corbin, Fabien Aubé, Marie Teixeira, Christian Pinset, Laurent Schaeffer, Gaëlle Legube, François-Loïc Cosset, Els Verhoeyen, Théophile Ohlmann, Emiliano P. Ricci
Published in: Nature Communications, Issue 10/1, 2019, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-018-07845-z

Non-AUG HIV-1 uORF translation elicits specific T cell immune response and regulates viral transcript expression

Author(s): Emmanuel Labaronne, Didier Décimo, Lisa Bertrand, Laura Guiguettaz, Thibault J. M. Sohier, David Cluet, Valérie Vivet-Boudou, Ana Luiza Chaves Valadão, Clara Dahoui, Pauline François, Isabelle Hatin, Olivier Lambotte, Assia Samri, Brigitte Autran, Lucie Etienne, Caroline Goujon, Jean-Christophe Paillart, Olivier Namy, Bertha Cecilia Ramirez, Théophile Ohlmann, Arnaud Moris, Emiliano P. Ricci
Published in: Nature Communications, Issue 16, 2025, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-025-56772-3

"Delivery of the Cas9/sgRNA Ribonucleoprotein Complex in Immortalized and Primary Cells via Virus-like Particles (""Nanoblades"")"

Author(s): Philippe E. Mangeot, Laura Guiguettaz, Thibault J. M. Sohier, Emiliano P. Ricci
Published in: Journal of Visualized Experiments, Issue 169, 2021, ISSN 1940-087X
Publisher: MYJoVE Corporation
DOI: 10.3791/62245

Pseudomonas aeruginosa cleaves the decoding center of Caenorhabditis elegans ribosomes

Author(s): Alejandro Vasquez-Rifo, Emiliano P. Ricci, Victor Ambros
Published in: PLOS Biology, Issue 18/12, 2020, Page(s) e3000969, ISSN 1545-7885
Publisher: Plos
DOI: 10.1371/journal.pbio.3000969

Ribosomes guide pachytene piRNA formation on long intergenic piRNA precursors

Author(s): Yu H. Sun, Jiang Zhu, Li Huitong Xie, Ziwei Li, Rajyalakshmi Meduri, Xiaopeng Zhu, Chi Song, Chen Chen, Emiliano P. Ricci, Zhiping Weng, Xin Zhiguo Li
Published in: Nature Cell Biology, Issue 22/2, 2020, Page(s) 200-212, ISSN 1465-7392
Publisher: Nature Publishing Group
DOI: 10.1038/s41556-019-0457-4