Objective
METAFORA develops a disruptive blood-based In Vitro Diagnostic platform called METAdiag, METAdiag monitors cells’ energetic needs thanks to unique, proprietary biomarkers (Receptor Binding Domains or RBDs), able to quantify nutrient transporters used by cells to feed on glucose, amino acids, vitamins and other essential nutrient transporters at the cell’s surface.
Cutting edge algorithms using Artificial Intelligence to handle big data participate in generating actionable results to physicians for routine clinical practice,
METAglut1 is a first test developed to fill a medical unmet need, i.e.: the easy and early diagnosis of a debilitating but curable neuro-metabolic disease in children, GLUT1 Deficiency Syndrome. METAglut1 test’s positive results have been published in a leading scientific journal, has been CE-marked and is at the basis of a partnering agreement with CERBA Healthcare, a leading Medical Testing Laboratory.
Next steps include:
o A large scale validation study in Europe to secure the reimbursement of the test
o Downsizing of the test as a finger prick blood test
o Dissemination of METAglut1 in Europe big 5 countries (Germany, UK, France, Italy and Spain) and North America via business development effort and market access
o Extension of the test application to newborn screening in the USA
Following the validation and commercial launch of this first test, next applications to come out of the METAdiag platform include a breakthrough test enabling the diagnosis and therapeutic monitoring of cancers, with a market launch contemplated 3 years after the Phase 2 project ends,
METAFORA anticipates cumulative revenues of over €52M and 75 jobs created 5 years after the commercialization of our first test, and ambitions to become a key player in the IVD market.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences computer and information sciences artificial intelligence
- natural sciences computer and information sciences data science big data
- natural sciences chemical sciences organic chemistry amines
- engineering and technology medical engineering medical laboratory technology laboratory samples analysis
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.3.1. - SOCIETAL CHALLENGES - Health, demographic change and well-being
MAIN PROGRAMME
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H2020-EU.3.1.3. - Treating and managing disease
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
SME-2 - SME instrument phase 2
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-SMEInst-2016-2017
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
75014 Paris
France
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.