Vaccines and Infectious Diseases in the Ageing PopuLation

Deliverables

Documents, reports (14)

Database on information needs and preferences of elderly regarding information provision (channel, source and template)

Report on the review of models developed on infectious diseases in elderly

Report and model access for a static model with scenario testing

Report of gaps linked to solutions in collaboration with WP1 in order to well develop the models

Database with information on perceptions, attitude, and intention of elderly on vaccination (including vaccination hesitancy)

Report on how the patient flow can be measured and identified in the two pilot studies of WP1 and options for a generic application of the approach

Systematic review of qualitative studies of barriers and facilitators to the uptake of educational interventions

Report on the different intervention options that could be developed in an aging population and applicable to the local circumstances against infections. Those intervention options should be considered in collaboration with the other WPs

Identify vaccine (hypo) responders (individuals at risk) per age group and the level of vaccine response based on classical read-outs (antibody responses against influenza by HI assays and pneumococcal serotypes through multiplex immune-assay)

Identify vaccine hypo responders individuals at risk per age group and the level of vaccine response based on classical readouts antibody responses against influenza by HI assays and pneumococcal serotypes through multiplex immuneassay

Report and model access for a compartmental model with scenario testing as needed

Network analysis elderly including trust in HCW that are indicated by the elderly regarding vaccination

Report on burden methodologies and data sources to assess potential & gaps

Report on what type of heterogeneity, levels (categorical or continuous), and measurement process are reported in elderly

Systematic review of highly effective educational interventions

Demonstrators, pilots, prototypes (5)

Retrospective Pilot study protocol

Pilot study protocol

Midterm recruitment report in clinical vaccine study

Report on status of posting results in clinical vaccines study

First study subject approvals package in clinical vaccine study

Prospective Pilot study protocol synopsis

Websites, patent fillings, videos etc. (1)

Develop VITAL website

Other (1)

Mapping of existing training, learning needs and objectives

Mapping of existing training learning needs and objectives

Publications

Peer reviewed articles (12)

Vaccination of older adults: Influenza, pneumococcal disease, herpes zoster, COVID-19 and beyond.

Author(s): Weinberger B
Published in: BMC Immunity & Ageing, Vol. 18 Art. Nr 38, 2021, ISSN 1742-4933
Publisher: BioMed Central
DOI: 10.1186/s12979-021-00249-6

European data sources for computing burden of (potential) vaccine-preventable diseases in ageing adults

Author(s): Estelle Méroc, Janeri Fröberg, Timea Almasi, Brita Askeland Winje, Alejandro Orrico-Sánchez, Anneke Steens, Scott A. McDonald, Kaatje Bollaerts & Mirjam J. Knol
Published in: BMC Infectious Diseases, 21, Article number: 345, 2021, ISSN 1471-2334
Publisher: BioMed Central
DOI: 10.1186/s12879-021-06017-7

Preventing infectious diseases for healthy ageing: The VITAL public-private partnership project

Author(s): Debbie Van Baarle, Kaatje Bollaerts, Giuseppe Del Giudice, Stephen Lockhart, Christine Luxemburger, Maarten J. Postma, Aura Timen, Baudouin Standaert
Published in: Vaccine, 38/37, 2020, Page(s) 5896-5904, ISSN 0264-410X
Publisher: Elsevier BV
DOI: 10.1016/j.vaccine.2020.07.005

Cost-Effectiveness of Pediatric Influenza Vaccination in The Netherlands,

Author(s): Pieter T. de Boer, Lisa Nagy, Franklin C.K. Dolk, Jan C. Wilschut, Richard Pitman, Maarten J. Postma,
Published in: Value in Health, Volume 24, Issue 1, 2021, ISSN 1098-3015
Publisher: Blackwell Publishing Inc.
DOI: 10.1016/j.jval.2020.10.011

Precision Medicine and Vaccination of Older Adults: From Reactive to Proactive (A Mini-Review)

Author(s): T. Mark Doherty, Alberta Di Pasquale, Jean-Pierre Michel, Giuseppe Del Giudice
Published in: Gerontology, 66/3, 2020, Page(s) 238-248, ISSN 0304-324X
Publisher: S. Karger AG
DOI: 10.1159/000503141

Healthcare workers’ perceptions and experiences of communicating with people over 50 years of age about vaccination: a qualitative evidence synthesis

Author(s): Claire GlentonBenedicte CarlsenSimon LewinManuela Dominique WennekesBrita Askeland WinjeRenske Eilerson behalf of the VITAL consortium
Published in: Cochrane Database of Systematic Reviews, Issue 7. Art. No.: CD013706, 2021, ISSN 1465-1858
Publisher: John Wiley & Sons,
DOI: 10.1002/14651858.cd013706.pub2

Consultations for Influenza-Like Illness in Primary Care in The Netherlands: A Regression Approach

Author(s): Dolk FCK, de Boer PT, Nagy L, Donker GA, Meijer A, Postma MJ, Pitman R.
Published in: Value in Health, Volume 24, Issue 1, 2021, ISSN 1098-3015
Publisher: Blackwell Publishing Inc.
DOI: 10.1016/j.jval.2020.10.013

"""Vaccines to Prevent Infectious Diseases in the Older Population: Immunological Challenges and Future Perspectives"""

Author(s): A, Wagner, B. Weinberger
Published in: Frontiers in Immunulogy, Vol 18 art. 174, 2020, ISSN 1664-3224
Publisher: Frontiers in Immunulogy
DOI: 10.3389/fimmu.2020.00717

Short- and long-term impact of vaccination against cytomegalovirus: a modeling study

Author(s): Ganna Rozhnova, Mirjam E. Kretzschmar, Fiona van der Klis, Debbie van Baarle, Marjolein Korndewal, Ann C. Vossen, Michiel van Boven
Published in: BMC Medicine, 18/1, 2020, ISSN 1741-7015
Publisher: BioMed Central
DOI: 10.1186/s12916-020-01629-3

Cost-Effectiveness of Quadrivalent Versus Trivalent Influenza Vaccination in the Dutch National Influenza Prevention Program

Author(s): Zeevat F, Crépey P, Dolk FCK, Postma AJ, Breeveld-Dwarkasing VNA, Postma MJ
Published in: Value in Health, Vol. 24 Iss 1, 2021, ISSN 1098-3015
Publisher: Blackwell Publishing Inc.
DOI: 10.1016/j.jval.2020.11.002

Vaccines and Vaccination against SARS-CoV-2: Considerations for the Older Population

Author(s): Weinberger B
Published in: Vaccines, 9, no. 12: 1435, 2021, ISSN 2076-393X
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/vaccines9121435

Exploratory Analysis of the Economically Justifiable Price of a Hypothetical RSV Vaccine for Older Adults in the Netherlands and the United Kingdom

Author(s): F Zeevat, J Luttjeboer, J H J Paulissen, J van der Schans, P Beutels, C Boersma, M J Postma, RESCEU Investigators
Published in: The Journal of Infectious Diseases, 2021, ISSN 0022-1899
Publisher: University of Chicago Press
DOI: 10.1093/infdis/jiab118