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Defining the role of Arp2/3 complex diversity at multiple scales of biology

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The role of the cell nucleus in mechanotransduction

Author(s): Cátia S. Janota, Francisco Javier Calero-Cuenca, Edgar R. Gomes
Published in: Current Opinion in Cell Biology, 63, 2020, Page(s) 204-211, ISSN 0955-0674
Publisher: Elsevier BV
DOI: 10.1016/

Ctdnep1 and Eps8L2 regulate dorsal actin cables for nuclear positioning during cell migration

Author(s): Francisco J. Calero-Cuenca, Daniel S. Osorio, Sofia Carvalho-Marques, Sreerama Chaitanya Sridhara, Luis M. Oliveira, Yue Jiao, Jheimmy Diaz, Cátia S. Janota, Bruno Cadot, Edgar R. Gomes
Published in: Current Biology, 31/7, 2021, Page(s) 1521-1530.e8, ISSN 0960-9822
Publisher: Cell Press
DOI: 10.1016/j.cub.2021.01.007

MICAL2 enhances branched actin network disassembly by oxidizing Arp3B-containing Arp2/3 complexes

Author(s): Chiara Galloni, Davide Carra, Jasmine V.G. Abella, Svend Kjær, Pavithra Singaravelu, David J. Barry, Naoko Kogata, Christophe Guérin, Laurent Blanchoin, Michael Way
Published in: Journal of Cell Biology, 220/8, 2021, ISSN 0021-9525
Publisher: Rockefeller University Press
DOI: 10.1083/jcb.202102043

Muscle repair after physiological damage relies on nuclear migration for cellular reconstruction

Author(s): William Roman, Helena Pinheiro, Mafalda R Pimentel, Jessica Segalés, Luis M Oliveira, Esther García-Domínguez, Mari Carmen Gómez-Cabrera, Antonio L Serrano, Edgar R Gomes, Pura Muñoz-Cánoves
Published in: science, 2022, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.abe5620

Shielding of actin by the endoplasmic reticulum impacts nuclear positioning

Author(s): Cátia S. Janota, Andreia Pinto, Anna Pezzarossa,Pedro Machado, Judite Costa, Pedro Campinho, Cláudio A. Franco, Edgar R. Gomes
Published in: Nature communications, 2022, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-022-30388-3

Cryo-EM of human Arp2/3 complexes provides structural insights into actin nucleation modulation by ARPC5 isoforms

Author(s): Ottilie von Loeffelholz, Andrew Purkiss, Luyan Cao, Svend Kjaer, Naoko Kogata, Guillaume Romet-Lemonne, Michael Way, Carolyn A. Moores
Published in: Biology Open, 9/7, 2020, Page(s) bio054304, ISSN 2046-6390
Publisher: Biology Open
DOI: 10.1242/bio.054304

mRNA distribution in skeletal muscle is associated with mRNA size.

Author(s): Helena Pinheiro, Mafalda Ramos Pimentel, Catarina Sequeira, Luis M Oliveira, Anna Pezzarossa, William Roman, Edgar R Gomes
Published in: Journal of Cell Science, 2021, ISSN 0021-9533
Publisher: The Company of Biologists Ltd.
DOI: 10.1242/jcs.256388