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Advancing osteoporosis medicine by observing bone microstructure and remodelling using a four-dimensional nanoscope

Project description

Innovative nanoscope unveils bone morphology in living animals

Osteoporosis is associated with weak and brittle bones, but our understanding of the disease remains limited. Therefore, there is an imminent need to properly characterise bone structure, the dynamics of bone remodelling as well as bone vascularisation. Scientists of the EU-funded 4-D nanoSCOPE project will combine state-of-the art image processing software and X-ray microscopy to obtain serial 3D images of bone. It is the first time that this approach has been possible in living animals and will allow scientists to determine bone microstructure as well as the impact of age, hormones, inflammation and treatment.

Call for proposal

ERC-2018-SyG
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Host institution

UNIVERSITATSKLINIKUM ERLANGEN
Address
Maximiliansplatz 2
91054 Erlangen
Germany
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 2 837 980

Beneficiaries (4)

UNIVERSITATSKLINIKUM ERLANGEN
Germany
EU contribution
€ 2 837 980
Address
Maximiliansplatz 2
91054 Erlangen
Activity type
Higher or Secondary Education Establishments
FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN-NUERNBERG
Germany
EU contribution
€ 2 755 050
Address
Schlossplatz 4
91054 Erlangen
Activity type
Higher or Secondary Education Establishments
HELMHOLTZ-ZENTRUM BERLIN FUR MATERIALIEN UND ENERGIE GMBH

Participation ended

Germany
EU contribution
€ 0
Address
Hahn Meitner Platz 1
14109 Berlin
Activity type
Research Organisations
FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.
Germany
EU contribution
€ 6 773 605
Address
Hansastrasse 27C
80686 Munchen
Activity type
Research Organisations