DELIVERy of advanced therapies for diabetes training network

Livrables

Data Managament Plan

Data management plan documented and place for the DELIVER consortium

Researcher Declarations

Researcher declarations for ESRs available.

4th Network Training Event Report

4th Network Training Event Report on activities held at EXPLORA

PhD theses

PhD theses available from ESRs at the end of the programme

Website and social media setup

Public website and social media presence established.

Postgraduate Diplomas Innovation-Entrepreneurship

ESRs will complete diplomas in Innovation- Entrepreneurship

Publications

Fluorescence lifetime metabolic mapping of hypoxia-induced damage in pancreatic pseudo-islets

Auteurs: Zbinden A, Carvajal Berrio DA, Urbanczyk M, Layland SL, Bosch M, Fliri S, Lu CE, Jeyagaran A, Loskill P, Duffy GP, Schenke-Layland K.
Publié dans: Journal of Biophotonics, 2020, ISSN 1864-063X
Éditeur: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/jbio.202000375

Decorin improves human pancreatic β-cell function and regulates ECM expression in vitro

Auteurs: Jeyagaran, Aline Zbinden, Chuan-En Lu, Julia Marzi, Laurence Kuhlburger, Sven Nahnsen, Shannon L Layland, Garry Duffy, Katja Schenke-Layland
Publié dans: Journal of the International Society of Matrix Biology, Numéro 2023 Jan;115:160-183, 2023, ISSN 0945-053X
Éditeur: Elsevier BV
DOI: 10.1016/j.matbio.2022.12.005

Dynamic actuation enhances transport and extends therapeutic lifespan in an implantable drug delivery platform

Auteurs: William Whyte, Debkalpa Goswami, Sophie X Wang, Yiling Fan, Niamh A Ward, Ruth E Levey, Rachel Beatty, Scott T Robinson, Declan Sheppard, Raymond O'Connor, David S Monahan, Lesley Trask, Keegan L Mendez, Claudia E Varela, Markus A Horvath, Robert Wylie, Joanne O'Dwyer, Daniel A Domingo-Lopez, Arielle S Rothman, Garry P Duffy, Eimear B Dolan, Ellen T Roche
Publié dans: Nature Communications, Numéro 2022 Aug 3;13(1):4496, 2022, ISSN 2041-1723
Éditeur: Nature Publishing Group
DOI: 10.1038/s41467-022-32147-w

Type 1 diabetes and engineering enhanced islet transplantation

Auteurs: Abiramy Jeyagaran, Chuan-En Lu , Aline Zbinden, Andreas L Birkenfeld, Sara Y Brucker, Shannon L Layland
Publié dans: Advanced Drug Delivery Reviews, Numéro 2022 Oct;189:114481, 2022, ISSN 0169-409X
Éditeur: Elsevier BV
DOI: 10.1016/j.addr.2022.114481

A Predictive Oxygen Durability Model to Analyze Oxygen Consumption of Insulin Producing Cells Encapsulated Within a Highly Oxygenated Hydrogel

Auteurs: Daniel A. Domingo-Lopez, Ruth E. Levey, Benjamin Brennan, Oliver Carroll, Sarah E. Gale, Jeffrey R. Millman, Liam McDonough, Helena M. Kelly, William Ronan, Garry P. Duffy
Publié dans: Advanced Materials Technologies, Numéro 2023, Vol.8(1), p.2200643, 2022, ISSN 2365-709X
Éditeur: Advanced Materials Technologies
DOI: 10.1002/admt.202200643

Medical devices, smart drug delivery, wearables and technology for the treatment of Diabetes Mellitus

Auteurs: Daniel A. Domingo-Lopez a 1, Giulia Lattanzi a 1, Lucien H. J. Schreiber a 1, Eimear J. Wallace a 1, Robert Wylie a, Janice O'Sullivan a, Eimear B. Dolan b d, Garry P. Duffy
Publié dans: Advanced Drug Delivery Reviews, Numéro Volume 185, June 2022, 2022, ISSN 0169-409X
Éditeur: Elsevier BV
DOI: 10.1016/j.addr.2022.114280

The Foreign Body Response to an Implantable Therapeutic Reservoir in a Diabetic Rodent Model

Auteurs: Rachel Beatty, Chuan-En Lu, Julia Marzi, Ruth E. Levey, Daniel Carvajal Berrio, Giulia Lattanzi, Robert Wylie, Raymond O'Connor, Eimear Wallace, Giulio Ghersi, Monica Salamone, Eimear B. Dolan, Shannon L. Layland, Katja Schenke-Layland, and Garry P. Duffy
Publié dans: Tissue Engineering Part C: Methods, Numéro Vol. 27, No. 10, 2021, Page(s) 515-528, ISSN 1937-3384
Éditeur: Mary Ann Liebert Inc.
DOI: 10.1089/ten.tec.2021.0163

Tethering zwitterionic polymer coatings to mediated glucose biosensor enzyme electrodes can decrease sensor foreign body response yet retain sensor sensitivity to glucose

Auteurs: Kavita Jayakumar, Anna Lielpetere, Daniel A. Domingo-Lopez, Ruth E. Levey, Garry P. Duffy, Wolfgang Schuhmann, Dónal Leech
Publié dans: Biosensors and Bioelectronics, Numéro Volume 219, 1 January 2023, 2023, ISSN 0956-5663
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.bios.2022.114815

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