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INtegrating Magnetic Resonance SPectroscopy and Multimodal Imaging for Research and Education in MEDicine

Project description

Integration of magnetic resonance spectroscopy and imaging in medical applications

Imaging technology plays a central role in modern healthcare, providing advanced techniques such as magnetic resonance (MR), magnetic resonance spectroscopy (MRS), magnetic resonance spectroscopy imaging (MRSI) and positron emission tomography (PET). The development of multi-parametric MR and hybrid imaging, combining the non-invasive metabolic information of MRS or MRSI with the high sensitivity of PET, is crucial for the improvement of diagnosis and disease monitoring. Funded by the Marie Skłodowska-Curie Actions programme, the INSPiRE-MED project will create a research training network of academic and industrial partners aimed at training early stage researchers in the field of medical imaging, including MRS and MRSI as well as their combination with MR imaging and PET.


INSPiRE-MED will provide research and training to 15 early career researchers in the field of medical imaging, specifically Magnetic Resonance Spectroscopy (MRS) and Spectroscopic Imaging (MRSI), combined with MR Imaging and Positron Emission Tomography (PET). INSPiRE-MED Fellows will acquire skills to develop careers contributing to innovative technological advances in medical imaging in a multi-disciplinary environment encompassing physics, mathematical and computer sciences leading to applications in medicine and biological sciences. The 12 academic and 9 industrial partners will provide the Fellows with transferable and generic skills as well as a comprehensive, wide-ranging education on the basic principles of medical imaging and image analysis. This fundamental knowledge will be combined with in-depth learning in a specific area, through local delivery via graduate schools, programme-wide INSPiRE-MED training activities and workshops and personal academic supervision by two INSPiRE-MED supervisors. This will enable them to successfully participate in developing new tools for clinicians.
MRS is a unique, non-invasive molecular technique that has proved useful for diagnosis and therapy management in disease models and patients. Despite its potential, the clinical uptake of MRS has lagged behind that of MRI and PET. Thus, INSPiRE-MED will have 3 objectives, encapsulated in 3 research Work Packages (WP):
1) Development of novel acquisition and processing techniques allowing MRS(I) to become a key tool in medical imaging (WP1); 2) Integration of innovative MRS(I) techniques in several key clinical and pre-clinical applications including a multimodal metabolic approach based on MR/PET (WP2); 3) Translation of most advanced research in MRS(I) and machine learning into clinical routine by means of a fully automatic software suite, building on the well-known jMRUI package ( to provide a prime tool in personalized medicine (WP 3).


Net EU contribution
€ 274 802,04
69622 Villeurbanne Cedex

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Auvergne-Rhône-Alpes Rhône-Alpes Rhône
Activity type
Higher or Secondary Education Establishments
Total cost
€ 274 802,04

Participants (13)

Partners (9)