Novel Biomaterial-based Device for the Treatment of Progressive MS- - An Integrated Pan- European Approach | PMSMatTrain | Projet | Résultats | H2020 | CORDIS

Livrables

Conference presentations (M 8, M12, M16, M20, M24, M32, M36, M42)

With input from all partners, the Management Team and the Dissemination and Outreach Committee (TC), this WP will ensure all aspects of Dissemination, Exploitation and Public Engagement are managed appropriately.

Manuscripts (M 20, M 24, M36, M40, M 45

With input from all partners, the Management Team and the Dissemination and Outreach Committee (TC), this WP will ensure all aspects of Dissemination, Exploitation and Public Engagement are managed appropriately.

Press Releases

With input from all partners, the Management Team and the Dissemination and Outreach Committee (TC), this WP will ensure all aspects of Dissemination, Exploitation and Public Engagement are managed appropriately.

Data Management Plan

Data management plan to be provided for open access data

Periodic reviews of the RPDPs and PhD progression (Month 12, 24, 36 and 48)

With input from all partners at the Supervisory Board and Training Committee (TC), this WP will ensure all aspects of the education and training programme are met.

Attendance at Open Days and Science Fairs (M12, M24, M36, M48)

With input from all partners, the Management Team and the Dissemination and Outreach Committee (TC), this WP will ensure all aspects of Dissemination, Exploitation and Public Engagement are managed appropriately.

Local training courses held

With input from all partners at the Supervisory Board and Training Committee (TC), this WP will ensure all aspects of the education and training programme are met.

Completion of ESR credits in transferable skills

With input from all partners at the Supervisory Board and Training Committee (TC), this WP will ensure all aspects of the education and training programme are met.

Publications

Brain Proteomic Signatures of an in vivo Model ofMultiple Sclerosis

Auteurs: M. Fucito, B. Ojha, R. Khorooshi, T. Owens, A. Nawrocki, M. Røssel Larsen, P. del Boccio, D.Pieragostino
Publié dans: Proteomic Forum EuPA Abstract Booklet, 2022
Éditeur: EuPA

Longitudinal evaluation of the therapeutic effect of APRIL in the Cuprizone mouse model of Multiple Sclerosis

Auteurs: Leonardo Ricciardi, Marion Decrop, Joëlle Van Rijswijk, Nicholas Vidas-Guscic, Julia Di Stefano, Tejaswini Kakunuri, Daniele Bertoglio, Bertrand Huard, Peter Ponsaerts, Marleen Verhoye
Publié dans: European Molecular Imaging Meeting-Programme, 2023, Page(s) Session PW14, poster 809
Éditeur: EMI

A drug repurposing study to enhance/target remyelination via the modulation of oligodendrocyte fate

Auteurs: Elif Nur Yılmaz, Raquel Guerrero González, Stefanie Albrecht, Tanja Kuhlmann
Publié dans: FENS Regional Meeting, 2023, Page(s) Session 1, Poster 14
Éditeur: FENS

Induction of inflammatory responses in bi- and tri-partite murine iPSC-derived neurospheroids

Auteurs: J. Di Stefano, E. Van Breedam, A. Quarta, J. Govaerts, L. Ricciardi, A. Silini3, O. Parolini, M. Verhoye, P. Ponsaerts
Publié dans: Glia, Numéro Bi-annual, 2023, Page(s) T16-165C
Éditeur: Wiley
DOI: 10.1002/glia.24419

Molecular Mechanisms of Physiological and Pathophysiological Processes inMultiple Sclerosis-like Models Ex Vivo and In Vivo

Auteurs: Maurine Fucito
Publié dans: European Neuroscience Conference by Doctoral Students-Posters, 2021, Page(s) P6A25
Éditeur: FENS

Selective vulnerability of cortical neurons in rat in vitro and ex vivomodels of cortical Progressive Multiple Sclerosis pathology

Auteurs: Daniela Costa
Publié dans: 2021, Page(s) P6A12
Éditeur: FENS, BRAIN, BNA

Brain Proteomic Signatures of an in vivo Model of Multiple Sclerosis

Auteurs: M. Fucito, B. Ojha2, R. Khorooshi, T. Owens, A. Nawrocki, M. Røssel Larsen, P. del Boccio, D. Pieragostino
Publié dans: 2022, Page(s) 120
Éditeur: European Proteomics Association

DETERMINING THE IMPACT OF MOLECULAR CROWDING AGENTS ON DEPOSITION OF COLLAGEN BY CULTURED MENINGEAL CELLS

Auteurs: Małgorzata Dąbrowska, Meletios‑Nikolaos Doulgkeroglou, Jill Mary McMahon, Dimitrios Zeugolis, Una FitzGerald
Publié dans: Acta Neurobioligae Experimentalis, 2022, Page(s) 51, ISSN 1689-0035
Éditeur: Acta Neurobiologiae Experimentalis

Deciphering (Phospho)proteomics Brain and Spinal Cord Signatures of an in vivo Model of Multiple Sclerosis

Auteurs: Maurine Fucito
Publié dans: Human Proteome Organization World Congress-Programme, 2022, Page(s) PP03.026
Éditeur: Human Proteome Organisation

Defining selective neuronal vulnerabilities in human/rat tissue and hNPCs-derived cortical neurons in vitro model

Auteurs: Daniela AD Costa, Raquel Guerrero, Jill McMahon, Tanja Kuhlmann, Una FitzGerald
Publié dans: FENS Regional Meeting, Portugal- Programme, 2023, Page(s) Poster Session II, Number 149
Éditeur: FENS

Assessing the therapeutic potential of APRIL using in vivo MRI and in vitro Proteomics in the Cuprizone mouse model of Multiple Sclerosis

Auteurs: Leonardo Ricciardi, Federica Di Marco, Marion Decrop, Joëlle van Rijswijk, Julia Di Stefano, Nicholas Vidas-Guscic, Tejaswini Kakunuri, Bertrand Huard, Damiana Pieragostino, Peter Ponsaerts, Marleen Verhoye
Publié dans: European Molecular Imaging Meeting-Programme, 2023, Page(s) PS21-05
Éditeur: EMIM

Hyaluronic acid-based devices for transcranial drug delivery to tackleneurodegenerative diseases

Auteurs: M. Al-waeel, L. Ricciard, P. Ponsaerts, M. Verhoye3 U. Fitzgerald, A. Pandit
Publié dans: Glia, Numéro Annual, 2023, Page(s) E5-E181
Éditeur: Wiley
DOI: 10.1002/glia.24418

ROSTRAL-TO-CAUDAL INCREASE IN METABOLIC ACTIVITY OF CULTURED EX VIVO SLICES OF NEONATAL RAT BRAIN

Auteurs: Małgorzata Dąbrowska, Jill Mcmahon, Bertrand Huard, Una Fitzgerald
Publié dans: FENS Forum 2022, 2022, Page(s) 2733, Board number S03-329
Éditeur: FENS

In vitro and in vivo testing of candidate neuroprotective compounds to target neurodegeneration in multiple sclerosis (MS)

Auteurs: Raquel Guerrero González, Elif Nur Yilmaz, Stefanie Albrecht, Tanja Kuhlmann
Publié dans: 2023, Page(s) Poster Session 1, Poster 18
Éditeur: FENS

Lack of strong innate immune reactivity renders macrophages alone unable to control productive Varicella-Zoster Virus infection in an isogenic human iPSC-derived neuronal co-culture model

Auteurs: Elise Van Breedam, Tamariche Buyle-Huybrecht, Jonas Govaerts, Pieter Meysman, Andrea Bours, Marlies Boeren, Julia Di Stefano, Thalissa Caers, Hans De Reu, Laura Dirkx, Jolien Schippers, Esther Bartholomeus, Marielle Lebrun, Catherine Sadzot-Delvaux, Paulina Rybakowska, Marta E Alarcón-Riquelme, Concepción Marañón, Kris Laukens, Peter Delputte, Benson Ogunjimi, Peter Ponsaerts
Publié dans: Frontiers in Immunology, 2023, ISSN 1664-3224
Éditeur: Frontiers
DOI: 10.3389/fimmu.2023.1177245

Influx of T cells into corpus callosum increases axonal injury, but does not change the course of remyelination in toxic demyelination

Auteurs: Elif Nur Yilmaz, Stefanie Albrecht, Katharina Groll, Christian Thomas, Lutz Wallhorn, Martin Herold, Stephanie Hucke, Luisa Klotz, Tanja Kuhlmann
Publié dans: GLIA, Numéro Volume71, Numéro4, 2023, Page(s) 991-1001, ISSN 0894-1491
Éditeur: John Wiley & Sons Inc.
DOI: 10.1002/glia.24319

Targeting Signaling Pathway Downstream of RIG-I/MAVS in the CNS Stimulates Production of Endogenous Type I IFN and Suppresses EAE.

Auteurs: Anne K Kronborg Hansen, Magdalena Dubik, Joanna Marczynska, Bhavya Ojha, Estanislao Nistal-Villán, Gloria González Aseguinolaza, Dina S Arengoth, Trevor Owens, Reza Khorooshi
Publié dans: International Journal of Molecular Sciences, 2022, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms231911292

Bioactive potential of natural biomaterials: identification, retention and assessment of biological properties

Auteurs: Kieran Joyce, Georgina Targa Fabra, Yagmur Bozkurt, Abhay Pandit
Publié dans: Signal Transduction and Targeted Therapy, Numéro 6/1, 2021, ISSN 2059-3635
Éditeur: Springer Nature
DOI: 10.1038/s41392-021-00512-8

Luminescent Human iPSC-Derived Neurospheroids Enable Modeling of Neurotoxicity After Oxygen–glucose Deprivation

Auteurs: Elise Van Breedam, Aleksandra Nijak, Tamariche Buyle-Huybrecht, Julia Di Stefano, Marlies Boeren, Jonas Govaerts, Alessandra Quarta, Tine Swartenbroekx, Eva Z. Jacobs, Björn Menten, Rik Gijsbers, Peter Delputte, Maaike Alaerts, Behrouz Hassannia, Bart Loeys, Zwi Berneman, Jean-Pierre Timmermans, Philippe G. Jorens, Tom Vanden Berghe, Erik Fransen, An Wouters, Winnok H. De Vos, Peter Ponsaerts.
Publié dans: Neurotherapeutics, 2022, ISSN 1933-7213
Éditeur: Elsevier BV
DOI: 10.1007/s13311-022-01212-z

Molecular Research in Multiple Sclerosis

Auteurs: Maurine Fucito and Damiana Pieragostino
Publié dans: International Journal of Molecular Sciences, 2022, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23052792

Novel Biomaterial-based Device for the Treatment of Progressive MS- - An Integrated Pan- European Approach

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