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Chromatin architecture and Design

Deliverables

Publications

In vivo temporal resolution of acute promyelocytic leukemia progression reveals a role of Klf4 in suppressing early leukemic transformation

Author(s): Glòria Mas, Fabio Santoro, Enrique Blanco, Gianni Paolo Gamarra Figueroa, François Le Dily, Gianmaria Frigè, Enrique Vidal, Francesca Mugianesi, Cecilia Ballaré, Arantxa Gutierrez, Aleksandra Sparavier, Marc A. Marti-Renom, Saverio Minucci, and Luciano Di Croce
Published in: Genes & Dev, 2022, ISSN 1549-5477
Publisher: CSH Press
DOI: 10.1101/gad.349115.121

PRC2 shields the potency of human stem cells

Author(s): Sergi Aranda, Livia Condemi, Luciano Di Croce
Published in: Nat Cell Bio, 2022, ISSN 1476-4679
Publisher: Nature Publishing Group
DOI: 10.1038/s41556-022-00937-5

Deciphering High-Resolution 3D Chromatin Organization via Capture Hi-C

Author(s): Hauth A, Galupa R, Servant N, Villacorta L, Hauschulz K, van Bemmel JG, Loda A, and Edith Heard
Published in: J. Vis. Exp., 2022, ISSN 1940-087X
Publisher: MYJoVE Corporation
DOI: 10.3791/64166

Histone editing elucidates the functional roles of H3K27 methylation and acetylation in mammals

Author(s): Aditya Sankar; Faizaan Mohammad; Arun Kumar Sundaramurthy; Hua Wang; Mads Lerdrup; Tulin Tatar; Kristian Helin
Published in: Nat Gen, 2022, ISSN 1546-1718
Publisher: Nature Publishing Group
DOI: 10.1038/s41588-022-01091-2

Nonlinear control of transcription through enhancer–promoter interactions

Author(s): Jessica Zuin, Gregory Roth, Yinxiu Zhan, Julie Cramard, Josef Redolfi, Ewa Piskadlo, Pia Mach, Mariya Kryzhanovska, Gergely Tihanyi, Hubertus Kohler, Mathias Eder, Christ Leemans, Bas van Steensel, Peter Meister, Sebastien Smallwood & Luca Giorgetti
Published in: Nature, 2022, ISSN 1476-4687
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-022-04570-y

Cohesin and CTCF control the dynamics of chromosome folding

Author(s): Pia Mach, Pavel I. Kos, Yinxiu Zhan, Julie Cramard, Simon Gaudin, Jana Tünnermann, Edoardo Marchi, Jan Eglinger, Jessica Zuin, Mariya Kryzhanovska, Sebastien Smallwood, Laurent Gelman, Gregory Roth, Elphège P. Nora, Guido Tiana & Luca Giorgetti
Published in: Nat Genet, 2022, ISSN 1546-1718
Publisher: Nature Publishing Group
DOI: 10.1038/s41588-022-01232-7

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