Deliverables Other (8) 1. TICARDIO conference TICARDIO conferences Dissemination plan Dissemination plan Agreements on joint degrees Administrative agreement to establish a joint Doctorate 3. Main outreach activity Main outreach activities 1. Training week Training weeks with basic and advanced courses Communication and outreach plan Communication and outreach plan Exploitation plan Exploitation plan ESRs selected and employed ESRs selected and employed Websites, patent fillings, videos etc. (1) TICARDIO website TICARDIO website Publications Peer reviewed articles (26) Properdin (factor P) as a new target cleaved by factor XIa: Intrinsic coagulation at the crossroads with inflammation Author(s): Luo Q, Wenzel P Published in: Res Pract Thromb Haemost., 2022, ISSN 2475-0379 Publisher: Wiley-Blackwell Publishing Ltd DOI: 10.1002/rth2.12835 Molecular Proteomics and Signalling of Human Platelets in Health and Disease Author(s): Huang J, Zhang P, Solari FA, Sickmann A, Garcia A, Jurk K, Heemskerk JWM Published in: International Journal of Molecular Sciences, 2021, ISSN 1422-0067 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/ijms22189860 Unsupervised clustering of venous thromboembolism patients by clinical features at presentation identifies novel endotypes that improve prognostic stratification Author(s): Pallares Robles A, Ten Cate V, Lenz M, Schulz A, Prochaska JH, Rapp S, Koeck T, Leineweber K, Heitmeier S, Opitz CF, Held M, Espinola-Klein C, Lackner KJ, Münzel T, Konstantinides SV, Ten Cate-Hoek A, Ten Cate H, Wild PS. Published in: Thrombosis Research, 2023, ISSN 0049-3848 Publisher: Pergamon Press DOI: 10.1016/j.thromres.2023.04.023 Plasma protein signatures for high on-treatment platelet reactivity to aspirin and clopidogrel in peripheral artery disease Author(s): G. Baidildinova, A. Pallares Robles, V. ten Cate, B.M.M. Kremers, S. Heitmeier, H. ten Cate, B.M.E. Mees, H.M.H. Spronk, P.S. Wild, A.J. ten Cate-Hoek, K. Jurk. Published in: Thromb. Res., 2023, ISSN 0049-3848 Publisher: Pergamon Press DOI: 10.1016/j.thromres.2023.08.017 Deletion of endothelial leptin receptors in mice promotes diet-induced obesity Author(s): Gogiraju R, Witzler C, Shahneh F, Hubert A, Renner L, Bochenek ML, Zifkos K, Becker C, Thati M, Schäfer K. Published in: Sci Rep., 2023, ISSN 2045-2322 Publisher: Nature Publishing Group DOI: 10.1038/s41598-023-35281-7 Protein expression profiling suggests relevance of noncanonical pathways in isolated pulmonary embolism Author(s): Vincent Ten Cate, Jürgen H. Prochaska, Andreas Schulz, Thomas Koeck, Alejandro Pallares Robles, Michael Lenz, Lisa Eggebrecht, Steffen Rapp, Marina Panova-Noeva, H. Ardeschir Ghofrani, F. Joachim Meyer, Christine Espinola-Klein, Karl J. Lackner, Matthias Michal, Alexander K. Schuster, Konstantin Strauch, Alexander M. Zink, Volker Laux, Stefan Heitmeier, Stavros V. Konstantinides, Thomas Münzel, Published in: Blood, Issue 137/19, 2021, Page(s) 2681-2693, ISSN 0006-4971 Publisher: American Society of Hematology DOI: 10.1182/blood.2019004571 Soluble Platelet Release Factors as Biomarkers for Cardiovascular Disease Author(s): Gaukhar Baidildinova, Magdolna Nagy, Kerstin Jurk, Philipp S. Wild, Hugo ten Cate, Paola E. J. van der Meijden Published in: Frontiers in Cardiovascular Medicine, Issue 8, 2021, ISSN 2297-055X Publisher: Front. Cardiovasc. Med DOI: 10.3389/fcvm.2021.684920 Association of FXI activity with thrombo-inflammation, extracellular matrix, lipid metabolism and apoptosis in venous thrombosis Author(s): Alejandro Pallares Robles; Vincent ten Cate; Andreas Schulz; Jürgen H. Prochaska; Steffen Rapp; Thomas Koeck; Marina Panova-Noeva; Stefan Heitmeier; Stephan Schwers; Kirsten Leineweber; Hans-Jürgen Seyfarth; Christian F. Opitz; Henri Spronk; Christine Espinola-Klein; Karl J. Lackner; Thomas Münzel; Miguel A. Andrade-Navarro; Stavros V. Konstantinides; Hugo ten Cate; Philipp S. Wild Published in: Scientific Reports, Issue 20452322, 2022, ISSN 2045-2322 Publisher: Nature Publishing Group DOI: 10.1038/s41598-022-13174-5 Blood coagulation and beyond: Position paper from the Fourth Maastricht Consensus Conference on Thrombosis Author(s): Akbalut C, Arisz R, Baaten C, Baildildinova G, Barakzie A, Bauersachs R, Ten Berg JM, van den Broek W, de Boer HC, Broker V, Buka R, Ten Cate H, Cate AT, De Luca C, De Simone I, Dignat-George F, Freson K, Gazzaniga G, van Gorp E, Habibi A, Henskens YMC, Iding AFJ, Khan A, Koenderink G, Konkoth A, Lacroix R, Lahiri T, Lam W, Lamerton R, Lorusso R, Luo Q, Maas C, McCarty OJT, van der Meijden P, Meij Published in: Thrombosis and Haemostasis, 2023, ISSN 2567-689X Publisher: Thieme DOI: 10.1055/a-2052-9175 Antagonistic Roles of Human Platelet Integrin αIIbβ3 and Chemokines in Regulating Neutrophil Activation and Fate on Arterial Thrombi Under Flow Author(s): Schönichen C, Montague SJ, Brouns SLN, Burston JJ, Cosemans JMEM, Jurk K, Kehrel BE, Koenen RR, Ní Áinle F, O'Donnell VB, Soehnlein O, Watson SP, Kuijpers MJE, Heemskerk JWM, Nagy M. Published in: Arteriosclerosis, Thrombosis, and Vascular Biology, 2023, ISSN 1079-5642 Publisher: Lippincott Williams & Wilkins Ltd. DOI: 10.1161/atvbaha.122.318767 The Serine/Threonine Protein Phosphatase 2A (PP2A) Regulates Syk Activity in Human Platelets Author(s): Stephanie Makhoul, Elena Kumm, Pengyu Zhang, Ulrich Walter, Kerstin Jurk Published in: International Journal of Molecular Sciences, Issue 21/23, 2020, Page(s) 8939, ISSN 1422-0067 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/ijms21238939 Clinical profile and outcome of isolated pulmonary embolism: a systematic review and meta-analysis Author(s): Ten Cate V, Prochaska JH, Schulz A, Nagler M, Robles AP, Jurk K, Koeck T, Rapp S, Düber C, Münzel T, Konstantinides SV, Wild PS Published in: EClinicalMedicine, 2023, ISSN 2589-5370 Publisher: The Lancet DOI: 10.1016/j.eclinm.2023.101973 Vitamin K antagonist use induces calcification and atherosclerotic plaque progression resulting in increased hypercoagulability Author(s): van Gorp RH, Baaten CCFMJ, Habibi A, Jaminon AMG, Peeters FECM, Leenders P, Crijns HJGMC, Heemskerk JWM, Reutelingsperger CP, Spronk HM, Schurgers LJ Published in: European Heart Journal Open, 2021, ISSN 2752-4191 Publisher: Oxford Academic DOI: 10.1093/ehjopen/oeab017 Multifaceted role of extracellular vesicles in atherosclerosis Author(s): Akhil Konkoth, Ronald Saraswat, Cléa Dubrou, Florence Sabatier, Aurélie S. Leroyer, Romaric Lacroix, Anne-Claire Duchez, Francoise Dignat-George Published in: Atherosclerosis, Issue 319, 2021, Page(s) 121-131, ISSN 0021-9150 Publisher: Elsevier BV DOI: 10.1016/j.atherosclerosis.2020.11.006 Discovery of four plasmatic biomarkers potentially predicting cardiovascular outcome in peripheral artery disease Author(s): Kremers BMM, Posma JN, Heitmeier S, Glunz J, Ten Cate H, Pallares Robles A, Daemen JHC, Ten Cate-Hoek AJ, Mees BME, Spronk HMH Published in: Science Reports, 2022, ISSN 2045-2322 Publisher: Nature Publishing Group DOI: 10.1038/s41598-022-23260-3 Differential Regulation of GPVI-Induced Btk and Syk Activation by PKC, PKA and PP2A in Human Platelets Author(s): Zhang P, Solari FA, Heemskerk JWM, Kuijpers MJE, Sickmann A, Walter U, Jurk K. Published in: International Journal of Molecular Sciences, 2023, ISSN 1422-0067 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/ijms24097776 Emerging Roles of RNA 3′-end Cleavage and Polyadenylation in Pathogenesis, Diagnosis and Therapy of Human Disorders Author(s): Jamie Nourse, Stefano Spada, Sven Danckwardt Published in: Biomolecules, Issue 10/6, 2020, Page(s) 915, ISSN 2218-273X Publisher: Biomolecules DOI: 10.3390/biom10060915 Exploring phenotypes of deep vein thrombosis in relation to clinical outcomes beyond recurrence Author(s): Iding AFJ, Robles AP, Ten Cate V, Ten Cate H, Wild PS, Ten Cate-Hoek AJ Published in: Journal of Thrombosis and Haemostasis, 2023, ISSN 1538-7933 Publisher: Blackwell Publishing Inc. DOI: 10.1016/j.jtha.2023.01.025 Subtype-specific plasma signatures of platelet-related protein releasate in acute pulmonary embolism Author(s): Baidildinova G, Ten Cate V, Nagler M, Panova-Noeva M, Rapp S, Köck T, Prochaska JH, Heitmeier S, Gerdes C, Schwers S, Konstantinides SV, Münzel T, Espinola-Klein C, Lackner KJ, Spronk HMN, Ten Cate H, van der Meijden PEJ, Leineweber K, Wild PS, Jurk K Published in: Thrombosis Research, 2022, ISSN 0049-3848 Publisher: Pergamon Press DOI: 10.1016/j.thromres.2022.10.005 Circulating microRNAs predict recurrence and death following venous thromboembolism Author(s): Ten Cate V, Rapp S, Schulz A, Pallares Robles A, Jurk K, Koeck T, Espinola-Klein C, Halank M, Seyfarth HJ, Beutel ME, Schuster AK, Marini F, Hobohm L, Lankeit M, Lackner KJ, Ruf W, Münzel T, Andrade-Navarro MA, Prochaska JH, Konstantinides SV, Wild PS. Published in: J Thromb Haemost, 2023, ISSN 1538-7933 Publisher: Blackwell Publishing Inc. DOI: 10.1016/j.jtha.2023.07.010 Off‐target effects of oral anticoagulants – vascular effects of vitamin K antagonist and non‐vitamin K antagonist oral anticoagulant dabigatran etexilate Author(s): Rick H. Gorp, Ingrid Dijkgraaf, Vanessa Bröker, Matthias Bauwens, Peter Leenders, Danyel Jennen, Marc R. Dweck, Jan Bucerius, Jacco J. Briedé, Joanne Ryn, Vincent Brandenburg, Felix Mottaghy, Henri M. H. Spronk, Chris P. Reutelingsperger, Leon J. Schurgers Published in: Journal of Thrombosis and Haemostasis, Issue 19/5, 2021, Page(s) 1348-1363, ISSN 1538-7933 Publisher: Blackwell Publishing Inc. DOI: 10.1111/jth.15289 Translational insights into mechanisms underlying residual venous obstruction and the role of factor XI, P-selectin and GPVI in recurrent venous thromboembolism Author(s): Iding AFJ, Kremers BMM, Nagy M, Robles AP, Ten Cate H, Spronk HMH, Ten Cate-Hoek AJ Published in: Thrombosis Research, 2023, ISSN 0049-3848 Publisher: Pergamon Press DOI: 10.1016/j.thromres.2022.11.023 Residual venous obstruction as an indicator of clinical outcomes following deep vein thrombosis: a management study Author(s): Aaron F.J. Iding; Bram M.M. Kremers; Alejandro Pallares Robles; Hugo ten Cate; Arina ten Cate Published in: Thrombosis and Haemostasis, Issue 1, 2023, ISSN 2567-689X Publisher: Thieme DOI: 10.1055/a-2059-4737 Predictive value for increased activated factor XI activity in acute venous thromboembolism Author(s): Nagy M, Robles AP, Visser M, Koeck T, Ten Cate V, Ten Cate-Hoek AJ, Schwers S, Heitmeier S, Ten Cate H, Wild PS, Spronk HMH Published in: Journal of Thrombosis and Haemostasis, 2023, ISSN 1538-7933 Publisher: Blackwell Publishing Inc. DOI: 10.1016/j.jtha.2023.02.031 Extracellular Vesicles and Thrombosis: Update on the Clinical and Experimental Evidence Author(s): Konstantinos Zifkos, Christophe Dubois, Katrin Schäfer Published in: International Journal of Molecular Sciences, Issue 22/17, 2021, Page(s) 9317, ISSN 1422-0067 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/ijms22179317 The Bidirectional Link Between RNA Cleavage and Polyadenylation and Genome Stability: Recent Insights From a Systematic Screen Author(s): Spada S, Luke B, Danckwardt S Published in: frontiers in Genetics, 2022, ISSN 1664-8021 Publisher: Frontiers Media DOI: 10.3389/fgene.2022.854907 Searching for OpenAIRE data... There was an error trying to search data from OpenAIRE No results available
