Descripción del proyecto
Tratamientos regenerativos para las nefropatías
La insuficiencia renal crónica se caracteriza por una pérdida gradual de la función renal que requiere diálisis o, en casos extremos, un trasplante renal. Los avances en la biología de las células madre permiten desarrollar tratamientos regenerativos destinados a reparar o sustituir el tejido renal dañado. El objetivo del proyecto RenalToolBox, financiado con fondos europeos, es desarrollar tecnologías que faciliten la traslación de estas intervenciones regenerativas basadas en células a la práctica clínica. El proyecto implica la formación multidisciplinaria y multisectorial de jóvenes investigadores en los campos de los tratamientos celulares y la medicina regenerativa. Los alumnos desarrollarán nuevas herramientas de diagnóstico y se centrarán en tratamientos basados en células estromales mesenquimales.
Objetivo
The RenalToolBox ITN comprises a team of world-leading clinicians, scientists and industrialists from academia and private enterprise whose common goal is to develop innovative medical devices and imaging technologies to expedite the translation of cell-based regenerative medicine therapies (RMTs) to the clinic. The target disease for RenalToolBox is kidney disease, the incidence of which is increasing annually. The ITN provides an excellent framework for training 15 early stage researchers (ESRs) in a range of technological, entrepreneurial and transferable skills that will not only enhance their career prospects, but will also boost European scientific excellence and business innovation. By the end of the programme, the ESRs will have benefitted from a comprehensive multidisciplinary and multi-sectoral training experience that will equip them to expedite progress in the emerging supradisciplinary fields of biomedical devices, bio-imaging, cellular therapeutics and regenerative medicine. The research training objectives are as follows: 1. Train the young researchers in the development of diagnostic devices and novel tracers for monitoring renal function. 2. Apply cutting-edge imaging technologies to evaluate the safety and efficacy of novel cell-based RMTs in a rodent model of kidney disease. 3. Assess the safety and efficacy of different sources of mesenchymal stromal cells and explore the mechanisms whereby these cells can ameliorate kidney disease. This comprehensive training programme will endow the young researchers with the necessary scientific and industrial skills to ensure their employability and readiness to engage and lead the next European generation of scientists-entrepreneurs.
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MSCA-ITN - Marie Skłodowska-Curie Innovative Training Networks (ITN)Coordinador
L69 7ZX Liverpool
Reino Unido