Protometabolic pathways: exploring the chemical roots of systems biology

Project Information

ProtoMet

Grant agreement ID: 813873

DOI 10.3030/813873

Project closed

EC signature date 6 August 2018

Start date 1 November 2018

End date 31 October 2023

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost € 2 174 048,28

EU contribution € 2 174 048,28

Coordinated by

UNIVERSITA DEGLI STUDI DI TRENTO
Italy

Deliverables

Documents, reports (2)

Dissemination Plan

D5.2 Dissemination plan (M6).

Final dissemination report

D5.5 Final Dissemination report (M60).

Websites, patent fillings, videos etc. (1)

ProtoMet Website launch

D5.1 ProtoMet Website (M3).

Other (2)

Symposium

D.4.6 ProtoMet Symposium (M42).

ProtoMet Summer School

D.4.5 ProtoMet Summer School (M18) (M30).

Publications

Peer reviewed articles (16)

A Nonenzymatic Analog of Pyrimidine Nucleobase Biosynthesis

Author(s): Jing Yi; Harpreet Kaur; Wahnyalo Kazöne; Sophia A. Rauscher; Louis‐Albin Gravillier; Kamila B. Muchowska; Joseph Moran
Published in: Angewandte Chemie International Edition, Issue 15, 2022, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/ange.202117211

Definitions of life as epistemic tools that reflect and foster the advance of biological knowledge

Author(s): Alba Amilburu; Alvaro Moreno; Kepa Ruiz-Mirazo
Published in: Synthese, Issue 4, 2020, ISSN 1573-0964
Publisher: Springer
DOI: 10.1007/s11229-020-02736-7

Stability characterization of microfluidics lipid-stabilized double emulsions under physiologically-relevant conditions

Author(s): Camila Betterelli Giuliano; Joseph Moran; Jessica Ayache; Lisa Muiznieks
Published in: Open Research Europe, Issue 11, 2022, ISSN 2732-5121
Publisher: European Commission
DOI: 10.12688/openreseurope.14766.1

Mechanistic Insight into Metal Ion-Catalyzed Transamination.

Author(s): Robert J. Mayer; Harpreet Kaur; Sophia A. Rauscher; Joseph Moran
Published in: Journal of the American Chemical Society, Issue 17, 2021, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.1c08535

The Construction of Biological ‘Inter-Identity’ as the Outcome of a Complex Process of Protocell Development in Prebiotic Evolution

Author(s): Kepa Ruiz-Mirazo, Ben Shirt-Ediss, Miguel Escribano-Cabeza, Alvaro Moreno
Published in: Frontiers in Physiology, Issue 11, 2020, ISSN 1664-042X
Publisher: Frontiers Research Foundation
DOI: 10.3389/fphys.2020.00530

Methods to identify and characterize iron-sulfur oligopeptides in water

Author(s): Valer L, Rossetto D, Scintilla S, Tomar A, Nader S, Hu YJ, Betinol IO, Mansy SS
Published in: Canadian Journal of Chemistry, 2022, ISSN 2090-9071
Publisher: Canadian Science Publishing
DOI: 10.1139/cjc-2021-0237

Wasserstoff ermöglicht Teile des reduktiven Krebs‐Zyklus unter Katalyse von Metallen oder Meteoriten

Author(s): Sophia A. Rauscher; Joseph Moran
Published in: Angewandte Chemie, Issue 9, 2022, ISSN 0044-8249
Publisher: Wiley ONline
DOI: 10.1002/ange.202212932

"""Minimal metabolism"": A key concept to investigate the origins and nature of biological systems."

Author(s): Nino Lauber; Christoph Flamm; Kepa Ruiz-Mirazo
Published in: Bio Essays, Issue 11, 2021, ISSN 1475-4762
Publisher: Wiley online
DOI: 10.1002/bies.202100103

Hydrogen Drives Part of the Reverse Krebs Cycle under Metal or Meteorite Catalysis

Author(s): Sophia A. Rauscher; Joseph Moran
Published in: Angewandte Chemie International Edition, Issue 15, 2022, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202212932

Ferric heme b in aqueous micellar and vesicular systems: State-of-the-art and challenges

Author(s): Cvjetan, Nemanja; Walde, Peter Johann
Published in: Royal Society Chemistry Advances, 12, 13154-13167, Issue 8, 2022, ISSN 2046-2069
Publisher: Royal Society of Chemistry
DOI: 10.3929/ethz-b-000601176

Statistical mechanics of biomolecular condensates via cavity methods

Author(s): Nino Lauber, Ondrej Tichacek, Rudrarup Bose,Christoph Flamm,Luca Leuzzi,Dora Tang, Kepa Ruiz-Mirazo,and Daniele De Martino
Published in: IScience, 2023, ISSN 2589-0042
Publisher: Science Direct
DOI: 10.1016/j.isci.2023.106300

Multivesicular Vesicles.− Preparations and Applications.

Author(s): Peter Walde, Camila Beterelli Giuliano, Nemanja Cvjetan, Jessica Ayache
Published in: ChemSystemsChem, 2020, ISSN 2570-4206
Publisher: Chemistry Europe
DOI: 10.1002/syst.202000049

"Boundary versus enabling conditions for the origins of life: Comment on ""Mineral self-organization on a lifeless planet"" by García-Ruiz et al."

Author(s): Kepa Ruiz-Mirazo
Published in: Physics of Life Reviews, Issue 2, 2020, ISSN 1571-0645
Publisher: Elsevier BV
DOI: 10.1016/j.plrev.2020.06.001

Ferric heme <i>b</i> in aqueous micellar and vesicular systems: state-of-the-art and challenges

Author(s): Nemanja Cvjetan; Peter Walde
Published in: Quarterly Review of Biophysics, Issue 11, 2023, ISSN 1469-8994
Publisher: Cambrige University Press
DOI: 10.1017/s0033583522000130

Can coacervation unify disparate hypotheses in the origin of cellular life?

Author(s): Basusree Ghosh , Rudrarup Bose, T-Y. Dora Tang
Published in: Current Opinion in Colloid & Interface Science, 2021, ISSN 0021-9797
Publisher: Academic Press
DOI: 10.1016/j.cocis.2020.101415

Prebiotic triose glycolysis promoted by co-catalytic proline and phosphate in neutral water

Author(s): Álvaro F. Magalhães; Matthew W. Powner
Published in: Chemical Communications, Issue 14, 2022, ISSN 1359-7345
Publisher: Royal Society of Chemistry
DOI: 10.1039/d2cc05466c