Protometabolic pathways: exploring the chemical roots of systems biology

Informazioni relative al progetto

ProtoMet

ID dell’accordo di sovvenzione: 813873

DOI 10.3030/813873

Progetto chiuso

Data della firma CE 6 Agosto 2018

Data di avvio 1 Novembre 2018

Data di completamento 31 Ottobre 2023

Finanziato da

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Costo totale € 2 174 048,28

Contributo UE € 2 174 048,28

Coordinato da

UNIVERSITA DEGLI STUDI DI TRENTO
Italy

Risultati finali

Documents, reports (2)

Dissemination Plan

D5.2 Dissemination plan (M6).

Final dissemination report

D5.5 Final Dissemination report (M60).

Websites, patent fillings, videos etc. (1)

ProtoMet Website launch

D5.1 ProtoMet Website (M3).

Other (2)

Symposium

D.4.6 ProtoMet Symposium (M42).

ProtoMet Summer School

D.4.5 ProtoMet Summer School (M18) (M30).

Pubblicazioni

Peer reviewed articles (16)

A Nonenzymatic Analog of Pyrimidine Nucleobase Biosynthesis

Autori: Jing Yi; Harpreet Kaur; Wahnyalo Kazöne; Sophia A. Rauscher; Louis‐Albin Gravillier; Kamila B. Muchowska; Joseph Moran
Pubblicato in: Angewandte Chemie International Edition, Numero 15, 2022, ISSN 1433-7851
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/ange.202117211

Definitions of life as epistemic tools that reflect and foster the advance of biological knowledge

Autori: Alba Amilburu; Alvaro Moreno; Kepa Ruiz-Mirazo
Pubblicato in: Synthese, Numero 4, 2020, ISSN 1573-0964
Editore: Springer
DOI: 10.1007/s11229-020-02736-7

Stability characterization of microfluidics lipid-stabilized double emulsions under physiologically-relevant conditions

Autori: Camila Betterelli Giuliano; Joseph Moran; Jessica Ayache; Lisa Muiznieks
Pubblicato in: Open Research Europe, Numero 11, 2022, ISSN 2732-5121
Editore: European Commission
DOI: 10.12688/openreseurope.14766.1

Mechanistic Insight into Metal Ion-Catalyzed Transamination.

Autori: Robert J. Mayer; Harpreet Kaur; Sophia A. Rauscher; Joseph Moran
Pubblicato in: Journal of the American Chemical Society, Numero 17, 2021, ISSN 0002-7863
Editore: American Chemical Society
DOI: 10.1021/jacs.1c08535

The Construction of Biological ‘Inter-Identity’ as the Outcome of a Complex Process of Protocell Development in Prebiotic Evolution

Autori: Kepa Ruiz-Mirazo, Ben Shirt-Ediss, Miguel Escribano-Cabeza, Alvaro Moreno
Pubblicato in: Frontiers in Physiology, Numero 11, 2020, ISSN 1664-042X
Editore: Frontiers Research Foundation
DOI: 10.3389/fphys.2020.00530

Methods to identify and characterize iron-sulfur oligopeptides in water

Autori: Valer L, Rossetto D, Scintilla S, Tomar A, Nader S, Hu YJ, Betinol IO, Mansy SS
Pubblicato in: Canadian Journal of Chemistry, 2022, ISSN 2090-9071
Editore: Canadian Science Publishing
DOI: 10.1139/cjc-2021-0237

Wasserstoff ermöglicht Teile des reduktiven Krebs‐Zyklus unter Katalyse von Metallen oder Meteoriten

Autori: Sophia A. Rauscher; Joseph Moran
Pubblicato in: Angewandte Chemie, Numero 9, 2022, ISSN 0044-8249
Editore: Wiley ONline
DOI: 10.1002/ange.202212932

"""Minimal metabolism"": A key concept to investigate the origins and nature of biological systems."

Autori: Nino Lauber; Christoph Flamm; Kepa Ruiz-Mirazo
Pubblicato in: Bio Essays, Numero 11, 2021, ISSN 1475-4762
Editore: Wiley online
DOI: 10.1002/bies.202100103

Hydrogen Drives Part of the Reverse Krebs Cycle under Metal or Meteorite Catalysis

Autori: Sophia A. Rauscher; Joseph Moran
Pubblicato in: Angewandte Chemie International Edition, Numero 15, 2022, ISSN 1433-7851
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202212932

Ferric heme b in aqueous micellar and vesicular systems: State-of-the-art and challenges

Autori: Cvjetan, Nemanja; Walde, Peter Johann
Pubblicato in: Royal Society Chemistry Advances, 12, 13154-13167, Numero 8, 2022, ISSN 2046-2069
Editore: Royal Society of Chemistry
DOI: 10.3929/ethz-b-000601176

Statistical mechanics of biomolecular condensates via cavity methods

Autori: Nino Lauber, Ondrej Tichacek, Rudrarup Bose,Christoph Flamm,Luca Leuzzi,Dora Tang, Kepa Ruiz-Mirazo,and Daniele De Martino
Pubblicato in: IScience, 2023, ISSN 2589-0042
Editore: Science Direct
DOI: 10.1016/j.isci.2023.106300

Multivesicular Vesicles.− Preparations and Applications.

Autori: Peter Walde, Camila Beterelli Giuliano, Nemanja Cvjetan, Jessica Ayache
Pubblicato in: ChemSystemsChem, 2020, ISSN 2570-4206
Editore: Chemistry Europe
DOI: 10.1002/syst.202000049

"Boundary versus enabling conditions for the origins of life: Comment on ""Mineral self-organization on a lifeless planet"" by García-Ruiz et al."

Autori: Kepa Ruiz-Mirazo
Pubblicato in: Physics of Life Reviews, Numero 2, 2020, ISSN 1571-0645
Editore: Elsevier BV
DOI: 10.1016/j.plrev.2020.06.001

Ferric heme <i>b</i> in aqueous micellar and vesicular systems: state-of-the-art and challenges

Autori: Nemanja Cvjetan; Peter Walde
Pubblicato in: Quarterly Review of Biophysics, Numero 11, 2023, ISSN 1469-8994
Editore: Cambrige University Press
DOI: 10.1017/s0033583522000130

Can coacervation unify disparate hypotheses in the origin of cellular life?

Autori: Basusree Ghosh , Rudrarup Bose, T-Y. Dora Tang
Pubblicato in: Current Opinion in Colloid & Interface Science, 2021, ISSN 0021-9797
Editore: Academic Press
DOI: 10.1016/j.cocis.2020.101415

Prebiotic triose glycolysis promoted by co-catalytic proline and phosphate in neutral water

Autori: Álvaro F. Magalhães; Matthew W. Powner
Pubblicato in: Chemical Communications, Numero 14, 2022, ISSN 1359-7345
Editore: Royal Society of Chemistry
DOI: 10.1039/d2cc05466c