ADvanced nanocomposite MAterIals fOr in situ treatment and ultRAsound-mediated management of osteoarthritis

Deliverables

Intermediate data management and innovation management

Intermediate report on data management and innovation management

Initial data management plan

Report on initial data management plan

Preliminary dissemination, communication and exploitation plan

Preliminary report of the preliminary dissemination, communication and exploitation plan

Report on 1st ADMAIORA workshop
Project management handbook

Report of the project management handbook

Report on 3rd ADMAIORA workshop
Report on 2nd ADMAIORA workshop and other key communication events

Assembled innovative LIPUS stimulation set-ups

Demonstration of the assembled innovative LIPUS stimulation set-ups, and prototype testing

Pluronic-fibrinogen based hydrogel prototype development

Demonstration of Pluronic-fibrinogen based hydrogel prototypes

Preliminary brace skeleton

Demonstration of a preliminary brace skeleton prototype

PEG-fibrinogen based hydrogel prototype development

Demonstration of PEG-fibrinogen based hydrogel prototypes

Preliminary software structure

Demonstrator of a preliminary software structure

Preliminary foot-controlled pneumatic flow for bioprinting

Demonstration of a preliminary foot-controlled pneumatic system prototype for bioprinting

Project website

Presentation of the project website

Selected components for the innovative LIPUS stimulation set-ups

Selection of the components for the innovative LIPUS stimulation set-ups, and report of their technical datasheets

Publications

Design, Development and Validation of a Knee Brace to Standardize the US Imaging Evaluation of Knee Osteoarthritis

Author(s): A. Sorriento; A. Cafarelli; P. Spinnato; A. Russo; G. Lisignoli; F. Rabusseau; P. Cabras; E. Dumont; L. Ricotti
Published in: IEEE Journal of Translational Engineering in Health and Medicine, Vol 10, Pp 1-8 (2022), Issue 1, 2021, ISSN 2168-2372
Publisher: Institute of Electrical and Electronics Engineers Inc.
DOI: 10.1109/jtehm.2021.3137628

RGD-Functionalized Hydrogel Supports the Chondrogenic Commitment of Adipose Mesenchymal Stromal Cells

Author(s): C. Manferdini, D.Trucco, Y.Saleh, E. Gabusi, P.Dolzani, E.Lenzi, L.Vannozzi, L.Ricotti, G.Lisignoli
Published in: Gels, Issue 8, 2022, ISSN 2310-2861
Publisher: MDPI
DOI: 10.3390/gels8060382

A novel quantitative and reference-free ultrasound analysis to discriminate different concentrations of bone mineral content

Author(s): Angela Sorriento, Aliria Poliziani, Andrea Cafarelli, Leonardo Ricotti
Published in: Scientific Reports, 2021, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-020-79365-0

Graphene Oxide-doped Gellan Gum-PEGDA hydrogel mimicking the mechanical and lubrication properties of articular cartilage

Author(s): Diego Trucco; Lorenzo Vannozzi; Eti Teblum; Madina Telkhozhayeva; Gilbert Daniel Nessim; Saverio Affatato; Hind Al-Haddad; Gina Lisignoli; Leonardo Ricotti
Published in: Advanced Healthcare Materials, 2021, ISSN 2192-2659
Publisher: World Scientific
DOI: 10.1002/adhm.202001434

Graphene Oxide and Reduced Graphene Oxide Nanoflakes Coated with Glycol Chitosan, Propylene Glycol Alginate, and Polydopamine: Characterization and Cytotoxicity in Human Chondrocytes.

Author(s): Lorenzo Vannozzi; Enrico Catalano; Madina Telkhozhayeva; Eti Teblum; Alina Yarmolenko; Efrat Shawat Avraham; Rajashree Konar; Gilbert Daniel Nessim; Leonardo Ricotti
Published in: Nanomaterials, Issue 2, 2021, ISSN 2079-4991
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nano11082105

A Novel Approach for Multiple Material Extrusion in Arthroscopic Knee Surgery

Author(s): Tommaso Mazzocchi, Daniele Guarnera, Diego Trucco, Francesco Rocco Restaino, Lorenzo Vannozzi, Alessio Siliberto, Gina Lisignoli, Stefano Zaffagnini, Alessandro Russo, Leonardo Ricotti
Published in: Annals of Biomedical Engineering, Issue 51, 2023, Page(s) 550–565, ISSN 0090-6964
Publisher: Kluwer Academic Publishers
DOI: 10.1007/s10439-022-03061-5

Mesenchymal Stromal Cells Laden in Hydrogels for Osteoarthritis Cartilage Regeneration: A Systematic Review from In Vitro Studies to Clinical Applications

Author(s): Cristina Manferdini, Elena Gabusi, Yasmin Saleh, Enrico Lenzi, Giovanni D'Atri , Leonardo Ricotti , Gina Lisignoli
Published in: Cells, Issue 11, 2022, Page(s) 3969, ISSN 2073-4409
Publisher: MDPI
DOI: 10.3390/cells11243969

Modeling and Fabrication of Silk Fibroin-Gelatin-Based Constructs Using Extrusion-Based Three-Dimensional Bioprinting.

Author(s): Diego Trucco; Aarushi Sharma; Cristina Manferdini; Elena Gabusi; Mauro Petretta; Giovanna Desando; Leonardo Ricotti; Juhi Chakraborty; Sourabh Ghosh; Gina Lisignoli
Published in: ACS Biomaterials Science & Engineering, Issue 2, 2021, Page(s) 3306–3320, ISSN 2373-9878
Publisher: American Chemical Society
DOI: 10.1021/acsbiomaterials.1c00410

Wear Behavior Characterization of Hydrogels Constructs for Cartilage Tissue Replacement

Author(s): Saverio Affatato, Diego Trucco, Paola Taddei, Lorenzo Vannozzi, Leonardo Ricotti, Gilbert Daniel Nessim, Gina Lisignoli
Published in: Materials, Issue 14/2, 2021, Page(s) 428, ISSN 1996-1944
Publisher: MDPI Open Access Publishing
DOI: 10.3390/ma14020428

Novel Ultrathin Films Based on a Blend of PEG- b -PCL and PLLA and Doped with ZnO Nanoparticles

Author(s): Lorenzo Vannozzi, Pedro Gouveia, Pasqualantonio Pingue, Claudio Canale, Leonardo Ricotti
Published in: ACS Applied Materials & Interfaces, Issue 12/19, 2020, Page(s) 21398-21410, ISSN 1944-8244
Publisher: American Chemical Society
DOI: 10.1021/acsami.0c00154

Visible light-mediated cross-linking of injectable gellan gum hydrogels embedding human chondrocytes

Author(s): Diego Trucco, Lorenzo Vannozzi, Elena Gabusi, Enrico Lenzi, Cristina Manferdini, Alessia Bacci, Liliana Agresti, Maria Rosaria Pascale, Sandra Cristino, Gina Lisignoli, Leonardo Ricotti
Published in: Carbohydrate Polymer Technologies and Applications, Issue 6, 2023, Page(s) 100382, ISSN 2666-8939
Publisher: Elsevier
DOI: 10.1016/j.carpta.2023.100382

Benefits of Applying Nanotechnologies to Hydrogels in Efficacy Tests in Osteoarthritis Models—A Systematic Review of Preclinical Studies

Author(s): Chiara Delbaldo, Matilde Tschon, Lucia Martini, Milena Fini, and Giorgia Codispoti
Published in: International Journal of Molecular Sciences, Issue 23, 2022, Page(s) 8236, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23158236

Fabrication, Characterization, and Properties of Poly (Ethylene-Co-Vinyl Acetate) Composite Thin Films Doped with Piezoelectric Nanofillers

Author(s): Giulia Mariotti, Lorenzo Vannozzi
Published in: Nanomaterials, Issue 9/8, 2019, Page(s) 1182, ISSN 2079-4991
Publisher: MDPI AG
DOI: 10.3390/nano9081182

Higher Ultrasonic Frequency Liquid Phase Exfoliation Leads to Larger and Monolayer to Few-Layer Flakes of 2D Layered Materials

Author(s): Madina Telkhozhayeva, Eti Teblum, Rajashree Konar, Olga Girshevitz, Ilana Perelshtein, Hagit Aviv, Yaakov R. Tischler, Gilbert Daniel Nessim
Published in: Langmuir, 2021, ISSN 0743-7463
Publisher: American Chemical Society
DOI: 10.1021/acs.langmuir.0c03668

Scalable Synthesis of Few-Layered 2D Tungsten Diselenide (2H-WSe 2 ) Nanosheets Directly Grown on Tungsten (W) Foil Using Ambient-Pressure Chemical Vapor Deposition for Reversible Li-Ion Storage

Author(s): Rajashree Konar, Rosy, Ilana Perelshtein, Eti Teblum, Madina Telkhozhayeva, Maria Tkachev, Jonathan J. Richter, Elti Cattaruzza, Andrea Pietropolli Charmet, Paolo Stoppa, Malachi Noked, Gilbert Daniel Nessim
Published in: ACS Omega, Issue 5/31, 2020, Page(s) 19409-19421, ISSN 2470-1343
Publisher: ACS Publications
DOI: 10.1021/acsomega.0c01155

Primers for the Adhesion of Gellan Gum-Based Hydrogels to the Cartilage: A Comparative Study

Author(s): D.Trucco, L. Riacci, L.Vannozzi, C. Manferdini, L. Arrico, E. Gabusi, G.Lisignoli, L.Ricotti
Published in: Macromolecular Bioscience, Issue 22, 2022, Page(s) 2200096, ISSN 1616-5187
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/mabi.202200096

Ultrasound stimulation of piezoelectric nanocomposite hydrogels boosts chondrogenic differentiation in vitro, both in a normal and inflammatory milieu

Author(s): Ricotti, Leonardo; Cafarelli, Andrea; Manferdini, Cristina; Trucco, Diego; Vannozzi, Lorenzo; Gabusi, Elena; Fontana, Francesco; Dolzani, Paolo; Saleh, Yasmin; Lenzi, Enrico; Columbaro, Marta; Piazzi, Manuela; Bertacchini, Jessika; Aliperta, Andrea; Cain, Markys; Gemmi, Mauro; Parlanti, Paola; Jost, Carsten; Fedutik, Yuri; Nessim, Gilbert; Telkhozhayeva, Madina; Teblum, Eti; Dumont, Erik; Delbaldo
Published in: ACS Nano, Issue 18, 2024, Page(s) 2047–2065, ISSN 1936-0851
Publisher: American Chemical Society
DOI: 10.1021/acsnano.3c08738

Autophagy Is a Crucial Path in Chondrogenesis of Adipose-Derived Mesenchymal Stromal Cells Laden in Hydrogel

Author(s): Elena Gabusi , Enrico Lenzi , Cristina Manferdini , Paolo Dolzani , Marta Columbaro , Yasmin Saleh and Gina Lisignoli
Published in: Gels, Issue 8, 2022, Page(s) 766, ISSN 2310-2861
Publisher: MDPI
DOI: 10.3390/gels8120766

Optimal low-intensity pulsed ultrasound stimulation for promoting anti-inflammatory effects in macrophages

Author(s): Francesco Iacoponi, Andrea Cafarelli, Francesco Fontana, Tiziano Pratellesi, Erik Dumont, Ivana Barravecchia, Debora Angeloni, Leonardo Ricotti
Published in: APL Bioengineering, Issue 7, 2023, Page(s) 016114, ISSN 2473-2877
Publisher: AIP Publishing
DOI: 10.1063/5.0137881

Development and validation of low-intensity pulsed ultrasound systems for highly controlled in vitro cell stimulation

Author(s): F. Fontana, F .Iberite, A. Cafarelli, A. Aliperta, G. Baldi, E. Gabusi, P. Dolzani, S. Cristino, G. Lisignoli, T. Pratellesi, E.Dumont, L. Ricotti
Published in: Ultrasonics, 2021, ISSN 0041-624X
Publisher: Elsevier BV
DOI: 10.1016/j.ultras.2021.106495

Genipin-Based Crosslinking of Jellyfish Collagen 3D Hydrogels

Author(s): Laura Riacci, Angela Sorriento, Leonardo Ricotti
Published in: Gels, 2021, ISSN 2310-2861
Publisher: MDPI
DOI: 10.3390/gels7040238

Piezoelectric Nanomaterials Activated by Ultrasound: The Pathway from Discovery to Future Clinical Adoption.

Author(s): "Cafarelli, Andrea; Marino, Attilio; Vannozzi, Lorenzo; Puigmartí -Luis, Josep; Pané , Salvador; Ciofani, Gianni; Ricotti, Leonardo"
Published in: ACS Nano, Issue 4, 2021, Page(s) 11066–11086, ISSN 1936-086X
Publisher: American Chemical Society
DOI: 10.3929/ethz-b-000501652

ASC incapsulate in idrogeli 3D piezolettrici stimolati con ultrasuoni a bassa intensità per accelerare il processo di condrogenesi

Author(s): Yasmin Saleh, Cristina Manferdini, Elena Gabusi, Paolo Dolzani, Diego Trucco, Enrico Lenzi, Marta Columbaro, Lorenzo Vannozzi, Andrea Cafarelli, Leonardo Ricotti, Gina Lisignoli
Published in: Focus on Research and Innovation for Orthopaedics (IORS), 2022
Publisher: IORS

Low-Intesity pulsed ultrasound stimulation enhances chondrogenic differentiation of ASCs in a 3D hydrogel

Author(s): Cristina Manferdini, Elena Gabusi, Diego Trucco, Paolo Dolzani, Yasmin Saleh, Andrea Cafarelli, Leonardo Ricotti, Gina Lisignoli
Published in: EORS 2021 - 29th Annual Meeting of the European Orthopaedic Research Society, 2021
Publisher: European Orthopedic Research Society (EORS)

Low-Intensity pulsed ultrasound stimulation enhances chondrogenic differentiation of ASCs in a 3D hydrogel

Author(s): C. Manferdini, E. Gabusi, D. Trucco, P. Dolzani, Y. Saleh, A. Cafarelli, L. Ricotti, G. Lisignoli
Published in: Tissue Engineering and Regenerative Medicine International Society (TERMIS) conference, 2021
Publisher: Tissue Engineering and Regenerative Medicine International Society

Gellan gum/poly (ethylene glycol) di-acrylate hydrogels with tunable mechanical properties for articular cartilage engineering

Author(s): H. Al-Haddad, L. Vannozzi, D. Trucco, G. Lisignoli, L. Ricotti
Published in: TERMIS European Chapter Meeting, 2019
Publisher: NA

A ground-breaking approach for cartilage regeneration and osteoarthritis treatment: the ADMAIORA project

Author(s): Leonardo Ricotti
Published in: Nature Biomedical Engineering Conference, 2019
Publisher: NA

3D bioprinting handheld tool concept for innovative osteoarthritis treatment with stem cells utilization

Author(s): Krzysztof, Lenartowicz; Tomasz, Gapiński; Paulina, Galas; Małgorzata, Gonsior; Ricotti, Leonardo; Vannozzi, Lorenzo
Published in: Engineering of Biomaterials, Issue 153, 2019, Page(s) 44, ISSN 1429-7248
Publisher: Polskie Stowarzyszenie Biomateriałów

Characterization of photo-crosslinkable methacrylated gellan gum hydrogels for the in situ treatment of chondral defects

Author(s): Alessia Bacci, Diego Trucco, Lorenzo Vannozzi, Elena Gabusi, Enrico Lenzi, Cristina Manfredini, Liliana Agresti, Maria Rosaria Pascale, Sandra Cristino, Gina Lisignoli, Leonardo Ricotti
Published in: Annual Conference of the European Society for Biomaterials (ESB), 2023
Publisher: ESB

Non-invasive and quantitative assessment of tissues composition based on radio-frequency ultrasound data analysis

Author(s): A. Sorriento, A.Poliziani, A. Cafarelli, G.Valenza, L. Ricotti
Published in: Conference of the European Society for Artificial Organs (ESAO 2020), 2020
Publisher: ESAO

Dose-controlled low-intensity pulsed ultrasound and pulsed electromagnetic fields stimulations modulate inflammation in human macrophages

Author(s): Francesco Iacoponi, Fabio Orlando, Soria Gasparini, Tiziano Pratellesi, Andrea Cafarelli, Leonardo Ricotti
Published in: Proceedings of the Italian National Group of Bioengineering (GNB), 2023
Publisher: GNB

Visible light-crosslinked methacrylated gellan gum hydrogels for the embedding of human chondrocytes

Author(s): D. Trucco, L. Vannozzi, L. Agresti, A. Bacci, L. Riacci, G. Lisignoli and L. Ricotti
Published in: Biofabrication conference, 2022
Publisher: Biofabrication

Highly controlled and usable system for Low-Intensity Pulsed Ultrasound Stimulation of Cells

Author(s): F. Fontana, F. Iberite, L. Morchi, T. Pratellesi, A. Cafarelli, L. Ricotti
Published in: 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2019, Page(s) 2513-2516, ISBN 978-1-5386-1311-5
Publisher: IEEE
DOI: 10.1109/embc.2019.8857772

A user-friendly solution for remote ultrasound imaging

Author(s): Angela Sorriento, Giorgia Marola, Paolo Spinnato, Andrea Cafarelli, Leonardo Ricotti
Published in: IEEE International Ultrasonics Symposium (IUS), 2023
Publisher: IEEE

Influence of substrate stiffness on human induced pluripotent stem cells: preliminary results*

Author(s): F. Iberite, M. Salerno, C. Canale, A. Rosa, L. Ricotti
Published in: 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2019, Page(s) 1039-1043, ISBN 978-1-5386-1311-5
Publisher: IEEE
DOI: 10.1109/embc.2019.8857397

Low-Intensity pulsed ultrasound stimulation enhances chondrogenic differentiation of ASCs in a 3D hydrogel

Author(s): C. Manferdini, E. Gabusi, D.Trucco, P.Dolzani, Y.Saleh, A.Cafarelli, L.Ricotti,G.Lisignoli
Published in: STEMNET (Prima Conferenza della Federazione Associazioni Ricerca sulle Cellule Staminali), 2021
Publisher: STEMNET

Primers for the adhesion of gellan gum-based hydrogels to cartilage

Author(s): Laura Riacci, Diego Trucco, Lorenzo Vannozzi, Gina Lisignoli, Leonardo Ricotti
Published in: Materials Research Society Fall Meeting (MRS) conference, 2021
Publisher: Materials Research Society

Ultrasound counteracts inflammation and induces chondrogenic differentiation of ASCs in 3D piezoelectric hydrogels

Author(s): Cristina Manferdini, Elena Gabusi, Paolo Dolzani, Diego Trucco, Enrico Lenzi, Giovanni D'Atri, Lorenzo Vannozzi, Andrea Cafarelli, Leonardo Ricotti, Gina Lisignoli
Published in: Annual Meeting of the European Orthopaedic Research Society (EORS), 2023
Publisher: EORS

Ultrasound stimulation reduces inflammation and promotes the chondrogenic differentiation of adipose mesenchymal stromal cells embedded in a 3D piezoelectric hydrogel

Author(s): Enrico Lenzi, Cristina Manferdini, Elena Gabusi, Paolo Dolzani, Yasmin Saleh, Diego Trucco, Giovanni D'Atri, Marta Columbaro, Lorenzo Vannozzi, Andrea Cafarelli, Leonardo Ricotti, Gina Lisignoli
Published in: STEMNET meeting, 2023
Publisher: STEMNET

Nano-doped piezoelectric hydrogels and low-intensity pulsed ultrasound boost the chondrogenic differentiation of human adipose tissue-derived stromal cells

Author(s): L. Vannozzi, D. Trucco, C. Manferdini, A. Cafarelli, E. Gabusi, Y. Saleh, P. Dolzani, M. Columbaro, G. Lisignoli, and L. Ricotti
Published in: Biofabrication conference, 2022
Publisher: Biofabrication

Injectable gelatin-based photocurable fiber-reinforced hydrogel for the treatment of osteochondral defects

Author(s): Ignazio Niosi, Diego Trucco, Lorenzo Vannozzi, Silvia Farè, Leonardo Ricotti
Published in: Proceedings of the Italian National Group of Bioengineering (GNB), 2023
Publisher: GNB

Biological evaluation of highly controlled low-intensity pulsed ultrasound stimulation set-ups

Author(s): F. Iacoponi, F. Iberite, F. Fontana, L. Ricotti
Published in: Conference of the European Society for Artificial Organs (ESAO 2020), 2020
Publisher: ESAO

Low-Intensity pulsed ultrasound induces chondrogenic differentiation of adipose-stromal cells in a 3D piezoelectric hydrogel

Author(s): C. Manferdini, E. Gabusi, P.Dolzani, Y.Saleh, D.Trucco, E.Lenzi, M.Columbaro, L.Vannozzi, A.Cafarelli, L.Ricotti,G.Lisignoli
Published in: Tissue Engineering and Regenerative Medicine International Society (TERMIS) European Chapter, 2022
Publisher: TERMIS

Gellan gum-based hydrogels as injectable materials for cartilage tissue engineering

Author(s): L. Riacci, L. Vannozzi, L. Garcia-Hevia, L. Ricotti
Published in: Seventh National Congress of BioEngineering, 2020
Publisher: GNB

Ultrasound stimulation of piezoelectric hydrogels boosts chondrogenic differentiation of human adipose tissue-derived stromal cells

Author(s): Leonardo Ricotti, Diego Trucco, Lorenzo Vannozzi, Andrea Cafarelli, Cristina Manferdini, Elena Gabusi, Paolo Dolzani, Yasmin Saleh, Marta Columbaro, Gina Lisignoli
Published in: Annual Congress of the European Society for Artificial Organs (ESAO), 2022
Publisher: ESAO

Development of a bilayered hydrogel with cartilage-mimicking mechanical and lubrication properties

Author(s): L. Vannozzi, D. Trucco, E. Teblum, M. Telkhozhayeva, S. Affatato, G. Lisignoli, G.D. Nessim, L. Ricotti
Published in: Materials Research Society Fall Meeting (MRS) conference, 2020, 2020
Publisher: Materials Research Society

Piezoelectric nanomaterials and ultrasound for tissue regeneration

Author(s): Leonardo Ricotti
Published in: International Engineering in Medicine and Biology Conference (EMBC 2019), 2019
Publisher: IEEE

Low-Intensity pulsed ultrasound treatments: effects on chondrogenic differentiation of adipose-stromal cells in a 3D piezoelectric hydrogel

Author(s): E. Gabusi, C.Manferdini, P.Dolzani, Y.Saleh, D.Trucco, M.Columbaro, L.Vannozzi, A.Cafarelli, L.Ricotti,G.Lisignoli
Published in: Stem Cell Research Italy (SRC), 2022
Publisher: SRC

Low-Intensity pulsed ultrasound induces chondrogenic differentiation of adipose-stromal cells in a 3D piezoelectric hydrogel

Author(s): C. Manferdini, E. Gabusi, P.Dolzani, Y.Saleh, D.Trucco, M.Columbaro, L.Vannozzi, A.Cafarelli, L.Ricotti,G.Lisignoli
Published in: International Cartilage Regeneration & Joint Preservation Society Conference (ICRS), 2022
Publisher: ICRS

Nanocomposite thin films based on polyethylene vinyl acetate and piezoelectric nanomaterials

Author(s): L. Vannozzi, G. Mariotti, L. Ricotti
Published in: 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2019, Page(s) 1050-1053, ISBN 978-1-5386-1311-5
Publisher: IEEE
DOI: 10.1109/EMBC.2019.8857556

Quantitative ultrasound assessment of healthy and degenerated cartilage

Author(s): Lorena Guachi-Guachi, Angela Sorriento, Andrea Cafarelli, Paolo Dolzani, Enrico Lenzi, Gina Lisignoli, Leonardo Ricotti
Published in: IEEE International Ultrasonics Symposium (IUS), 2023
Publisher: IEEE

Ex-vivo quantitative ultrasound assessment of cartilage degeneration

Author(s): Angela Sorriento, Andrea Cafarelli, Gaetano Valenza, Leonardo Ricotti
Published in: 2021 43st Annual International Conference of the IEEE Engineering in Medicine and Biology Conference (EMBC), 2021
Publisher: IEEE
DOI: 10.1109/embc46164.2021.9630198

3D piezoelectric hydrogel stimulated by ultrasound to counteract inflammation by stimulating chondrogenic differentiation

Author(s): Cristina Manferdini, Elena Gabusi, Paolo Dolzani, Yasmin Saleh, Diego Trucco, Marta Columbaro, Lorenzo Vannozzi, Andrea Cafarelli, Leonardo Ricotti, Gina Lisignoli
Published in: International Cartilage Regeneration & Joint Preservation Society conference (ICRS), 2023
Publisher: ICRS

Low-Intensity pulsed ultrasound stimulation enhances chondrogenic differentiation of ASCs in a 3D hydrogel

Author(s): C. Manferdini, E. Gabusi, D. Trucco, P. Dolzani, Y. Saleh, A. Cafarelli, L. Ricotti, G. Lisignoli
Published in: European Society of Biomaterials (ESB) conference (2021), 2021
Publisher: European Society of Biomaterials (ESB)

Dose-controlled low-intensity pulsed ultrasound to modulate the inflammatory response

Author(s): F. Iacoponi, F. Fontana, E. Catalano, C. Manferdini, D. Trucco, A. Cafarelli, G. Lisignoli, L. Ricotti
Published in: Tissue Engineering and Regenerative Medicine International Society (TERMIS) conference, 2021
Publisher: Tissue Engineering and Regenerative Medicine International Society

Low-intensity pulsed ultrasound is effective in counteracting inflammation and inducing chondrogenic differentiation of adipose-stromal cells in 3d piezoelectric hydrogels

Nano-doped piezoelectric hydrogels and low-intensity pulsed ultrasound boost the chondrogenic differentiation of human adipose tissue-derived stromal cells

Author(s): Leonardo Ricotti, Diego Trucco, Lorenzo Vannozzi, Andrea Cafarelli, Cristina Manferdini, Elena Gabusi, Paolo Dolzani, Yasmin Saleh, Marta Columbaro, Gina Lisignoli
Published in: Annual Conference of the European Society of Biomaterials (ESB), 2022
Publisher: ESB

Injectable Hydrogels Reinforced with Structures obtained through Melt Electrowriting

Author(s): Diego Trucco, Rory Kibney, Lorenzo Vannozzi, Gina Lisignoli, Daniel J. Kelly, Leonardo Ricotti
Published in: Annual Conference of the European Society for Biomaterials (2023), 2023
Publisher: ESB

Low-Intensity pulsed ultrasound induces chondrogenic differentiation of adipose-stromal cells in a 3D piezoelectric hydrogel

Author(s): C. Manferdini, E. Gabusi, P.Dolzani, Y.Saleh, D.Trucco, M.Columbaro, L.Vannozzi, A.Cafarelli, L.Ricotti,G.Lisignoli
Published in: World Congress on Osteoarthritis (OARSI), 2022
Publisher: OARSI