ADvanced nanocomposite MAterIals fOr in situ treatment and ultRAsound-mediated management of osteoarthritis

Resultado final

Intermediate data management and innovation management

Intermediate report on data management and innovation management

Initial data management plan

Report on initial data management plan

Preliminary dissemination, communication and exploitation plan

Preliminary report of the preliminary dissemination, communication and exploitation plan

Report on 1st ADMAIORA workshop
Project management handbook

Report of the project management handbook

Report on 3rd ADMAIORA workshop
Report on 2nd ADMAIORA workshop and other key communication events

Assembled innovative LIPUS stimulation set-ups

Demonstration of the assembled innovative LIPUS stimulation set-ups, and prototype testing

Pluronic-fibrinogen based hydrogel prototype development

Demonstration of Pluronic-fibrinogen based hydrogel prototypes

Preliminary brace skeleton

Demonstration of a preliminary brace skeleton prototype

PEG-fibrinogen based hydrogel prototype development

Demonstration of PEG-fibrinogen based hydrogel prototypes

Preliminary software structure

Demonstrator of a preliminary software structure

Preliminary foot-controlled pneumatic flow for bioprinting

Demonstration of a preliminary foot-controlled pneumatic system prototype for bioprinting

Project website

Presentation of the project website

Selected components for the innovative LIPUS stimulation set-ups

Selection of the components for the innovative LIPUS stimulation set-ups, and report of their technical datasheets

Publicaciones

Design, Development and Validation of a Knee Brace to Standardize the US Imaging Evaluation of Knee Osteoarthritis

Autores: A. Sorriento; A. Cafarelli; P. Spinnato; A. Russo; G. Lisignoli; F. Rabusseau; P. Cabras; E. Dumont; L. Ricotti
Publicado en: IEEE Journal of Translational Engineering in Health and Medicine, Vol 10, Pp 1-8 (2022), Edición 1, 2021, ISSN 2168-2372
Editor: Institute of Electrical and Electronics Engineers Inc.
DOI: 10.1109/jtehm.2021.3137628

RGD-Functionalized Hydrogel Supports the Chondrogenic Commitment of Adipose Mesenchymal Stromal Cells

Autores: C. Manferdini, D.Trucco, Y.Saleh, E. Gabusi, P.Dolzani, E.Lenzi, L.Vannozzi, L.Ricotti, G.Lisignoli
Publicado en: Gels, Edición 8, 2022, ISSN 2310-2861
Editor: MDPI
DOI: 10.3390/gels8060382

A novel quantitative and reference-free ultrasound analysis to discriminate different concentrations of bone mineral content

Autores: Angela Sorriento, Aliria Poliziani, Andrea Cafarelli, Leonardo Ricotti
Publicado en: Scientific Reports, 2021, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-020-79365-0

Graphene Oxide-doped Gellan Gum-PEGDA hydrogel mimicking the mechanical and lubrication properties of articular cartilage

Autores: Diego Trucco; Lorenzo Vannozzi; Eti Teblum; Madina Telkhozhayeva; Gilbert Daniel Nessim; Saverio Affatato; Hind Al-Haddad; Gina Lisignoli; Leonardo Ricotti
Publicado en: Advanced Healthcare Materials, 2021, ISSN 2192-2659
Editor: World Scientific
DOI: 10.1002/adhm.202001434

Graphene Oxide and Reduced Graphene Oxide Nanoflakes Coated with Glycol Chitosan, Propylene Glycol Alginate, and Polydopamine: Characterization and Cytotoxicity in Human Chondrocytes.

Autores: Lorenzo Vannozzi; Enrico Catalano; Madina Telkhozhayeva; Eti Teblum; Alina Yarmolenko; Efrat Shawat Avraham; Rajashree Konar; Gilbert Daniel Nessim; Leonardo Ricotti
Publicado en: Nanomaterials, Edición 2, 2021, ISSN 2079-4991
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nano11082105

A Novel Approach for Multiple Material Extrusion in Arthroscopic Knee Surgery

Autores: Tommaso Mazzocchi, Daniele Guarnera, Diego Trucco, Francesco Rocco Restaino, Lorenzo Vannozzi, Alessio Siliberto, Gina Lisignoli, Stefano Zaffagnini, Alessandro Russo, Leonardo Ricotti
Publicado en: Annals of Biomedical Engineering, Edición 51, 2023, Página(s) 550–565, ISSN 0090-6964
Editor: Kluwer Academic Publishers
DOI: 10.1007/s10439-022-03061-5

Mesenchymal Stromal Cells Laden in Hydrogels for Osteoarthritis Cartilage Regeneration: A Systematic Review from In Vitro Studies to Clinical Applications

Autores: Cristina Manferdini, Elena Gabusi, Yasmin Saleh, Enrico Lenzi, Giovanni D'Atri , Leonardo Ricotti , Gina Lisignoli
Publicado en: Cells, Edición 11, 2022, Página(s) 3969, ISSN 2073-4409
Editor: MDPI
DOI: 10.3390/cells11243969

Modeling and Fabrication of Silk Fibroin-Gelatin-Based Constructs Using Extrusion-Based Three-Dimensional Bioprinting.

Autores: Diego Trucco; Aarushi Sharma; Cristina Manferdini; Elena Gabusi; Mauro Petretta; Giovanna Desando; Leonardo Ricotti; Juhi Chakraborty; Sourabh Ghosh; Gina Lisignoli
Publicado en: ACS Biomaterials Science & Engineering, Edición 2, 2021, Página(s) 3306–3320, ISSN 2373-9878
Editor: American Chemical Society
DOI: 10.1021/acsbiomaterials.1c00410

Wear Behavior Characterization of Hydrogels Constructs for Cartilage Tissue Replacement

Autores: Saverio Affatato, Diego Trucco, Paola Taddei, Lorenzo Vannozzi, Leonardo Ricotti, Gilbert Daniel Nessim, Gina Lisignoli
Publicado en: Materials, Edición 14/2, 2021, Página(s) 428, ISSN 1996-1944
Editor: MDPI Open Access Publishing
DOI: 10.3390/ma14020428

Novel Ultrathin Films Based on a Blend of PEG- b -PCL and PLLA and Doped with ZnO Nanoparticles

Autores: Lorenzo Vannozzi, Pedro Gouveia, Pasqualantonio Pingue, Claudio Canale, Leonardo Ricotti
Publicado en: ACS Applied Materials & Interfaces, Edición 12/19, 2020, Página(s) 21398-21410, ISSN 1944-8244
Editor: American Chemical Society
DOI: 10.1021/acsami.0c00154

Visible light-mediated cross-linking of injectable gellan gum hydrogels embedding human chondrocytes

Autores: Diego Trucco, Lorenzo Vannozzi, Elena Gabusi, Enrico Lenzi, Cristina Manferdini, Alessia Bacci, Liliana Agresti, Maria Rosaria Pascale, Sandra Cristino, Gina Lisignoli, Leonardo Ricotti
Publicado en: Carbohydrate Polymer Technologies and Applications, Edición 6, 2023, Página(s) 100382, ISSN 2666-8939
Editor: Elsevier
DOI: 10.1016/j.carpta.2023.100382

Benefits of Applying Nanotechnologies to Hydrogels in Efficacy Tests in Osteoarthritis Models—A Systematic Review of Preclinical Studies

Autores: Chiara Delbaldo, Matilde Tschon, Lucia Martini, Milena Fini, and Giorgia Codispoti
Publicado en: International Journal of Molecular Sciences, Edición 23, 2022, Página(s) 8236, ISSN 1422-0067
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23158236

Fabrication, Characterization, and Properties of Poly (Ethylene-Co-Vinyl Acetate) Composite Thin Films Doped with Piezoelectric Nanofillers

Autores: Giulia Mariotti, Lorenzo Vannozzi
Publicado en: Nanomaterials, Edición 9/8, 2019, Página(s) 1182, ISSN 2079-4991
Editor: MDPI AG
DOI: 10.3390/nano9081182

Higher Ultrasonic Frequency Liquid Phase Exfoliation Leads to Larger and Monolayer to Few-Layer Flakes of 2D Layered Materials

Autores: Madina Telkhozhayeva, Eti Teblum, Rajashree Konar, Olga Girshevitz, Ilana Perelshtein, Hagit Aviv, Yaakov R. Tischler, Gilbert Daniel Nessim
Publicado en: Langmuir, 2021, ISSN 0743-7463
Editor: American Chemical Society
DOI: 10.1021/acs.langmuir.0c03668

Scalable Synthesis of Few-Layered 2D Tungsten Diselenide (2H-WSe 2 ) Nanosheets Directly Grown on Tungsten (W) Foil Using Ambient-Pressure Chemical Vapor Deposition for Reversible Li-Ion Storage

Autores: Rajashree Konar, Rosy, Ilana Perelshtein, Eti Teblum, Madina Telkhozhayeva, Maria Tkachev, Jonathan J. Richter, Elti Cattaruzza, Andrea Pietropolli Charmet, Paolo Stoppa, Malachi Noked, Gilbert Daniel Nessim
Publicado en: ACS Omega, Edición 5/31, 2020, Página(s) 19409-19421, ISSN 2470-1343
Editor: ACS Publications
DOI: 10.1021/acsomega.0c01155

Primers for the Adhesion of Gellan Gum-Based Hydrogels to the Cartilage: A Comparative Study

Autores: D.Trucco, L. Riacci, L.Vannozzi, C. Manferdini, L. Arrico, E. Gabusi, G.Lisignoli, L.Ricotti
Publicado en: Macromolecular Bioscience, Edición 22, 2022, Página(s) 2200096, ISSN 1616-5187
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/mabi.202200096

Ultrasound stimulation of piezoelectric nanocomposite hydrogels boosts chondrogenic differentiation in vitro, both in a normal and inflammatory milieu

Autores: Ricotti, Leonardo; Cafarelli, Andrea; Manferdini, Cristina; Trucco, Diego; Vannozzi, Lorenzo; Gabusi, Elena; Fontana, Francesco; Dolzani, Paolo; Saleh, Yasmin; Lenzi, Enrico; Columbaro, Marta; Piazzi, Manuela; Bertacchini, Jessika; Aliperta, Andrea; Cain, Markys; Gemmi, Mauro; Parlanti, Paola; Jost, Carsten; Fedutik, Yuri; Nessim, Gilbert; Telkhozhayeva, Madina; Teblum, Eti; Dumont, Erik; Delbaldo
Publicado en: ACS Nano, Edición 18, 2024, Página(s) 2047–2065, ISSN 1936-0851
Editor: American Chemical Society
DOI: 10.1021/acsnano.3c08738

Autophagy Is a Crucial Path in Chondrogenesis of Adipose-Derived Mesenchymal Stromal Cells Laden in Hydrogel

Autores: Elena Gabusi , Enrico Lenzi , Cristina Manferdini , Paolo Dolzani , Marta Columbaro , Yasmin Saleh and Gina Lisignoli
Publicado en: Gels, Edición 8, 2022, Página(s) 766, ISSN 2310-2861
Editor: MDPI
DOI: 10.3390/gels8120766

Optimal low-intensity pulsed ultrasound stimulation for promoting anti-inflammatory effects in macrophages

Autores: Francesco Iacoponi, Andrea Cafarelli, Francesco Fontana, Tiziano Pratellesi, Erik Dumont, Ivana Barravecchia, Debora Angeloni, Leonardo Ricotti
Publicado en: APL Bioengineering, Edición 7, 2023, Página(s) 016114, ISSN 2473-2877
Editor: AIP Publishing
DOI: 10.1063/5.0137881

Development and validation of low-intensity pulsed ultrasound systems for highly controlled in vitro cell stimulation

Autores: F. Fontana, F .Iberite, A. Cafarelli, A. Aliperta, G. Baldi, E. Gabusi, P. Dolzani, S. Cristino, G. Lisignoli, T. Pratellesi, E.Dumont, L. Ricotti
Publicado en: Ultrasonics, 2021, ISSN 0041-624X
Editor: Elsevier BV
DOI: 10.1016/j.ultras.2021.106495

Genipin-Based Crosslinking of Jellyfish Collagen 3D Hydrogels

Autores: Laura Riacci, Angela Sorriento, Leonardo Ricotti
Publicado en: Gels, 2021, ISSN 2310-2861
Editor: MDPI
DOI: 10.3390/gels7040238

Piezoelectric Nanomaterials Activated by Ultrasound: The Pathway from Discovery to Future Clinical Adoption.

Autores: "Cafarelli, Andrea; Marino, Attilio; Vannozzi, Lorenzo; Puigmartí -Luis, Josep; Pané , Salvador; Ciofani, Gianni; Ricotti, Leonardo"
Publicado en: ACS Nano, Edición 4, 2021, Página(s) 11066–11086, ISSN 1936-086X
Editor: American Chemical Society
DOI: 10.3929/ethz-b-000501652

ASC incapsulate in idrogeli 3D piezolettrici stimolati con ultrasuoni a bassa intensità per accelerare il processo di condrogenesi

Autores: Yasmin Saleh, Cristina Manferdini, Elena Gabusi, Paolo Dolzani, Diego Trucco, Enrico Lenzi, Marta Columbaro, Lorenzo Vannozzi, Andrea Cafarelli, Leonardo Ricotti, Gina Lisignoli
Publicado en: Focus on Research and Innovation for Orthopaedics (IORS), 2022
Editor: IORS

Low-Intesity pulsed ultrasound stimulation enhances chondrogenic differentiation of ASCs in a 3D hydrogel

Autores: Cristina Manferdini, Elena Gabusi, Diego Trucco, Paolo Dolzani, Yasmin Saleh, Andrea Cafarelli, Leonardo Ricotti, Gina Lisignoli
Publicado en: EORS 2021 - 29th Annual Meeting of the European Orthopaedic Research Society, 2021
Editor: European Orthopedic Research Society (EORS)

Low-Intensity pulsed ultrasound stimulation enhances chondrogenic differentiation of ASCs in a 3D hydrogel

Autores: C. Manferdini, E. Gabusi, D. Trucco, P. Dolzani, Y. Saleh, A. Cafarelli, L. Ricotti, G. Lisignoli
Publicado en: Tissue Engineering and Regenerative Medicine International Society (TERMIS) conference, 2021
Editor: Tissue Engineering and Regenerative Medicine International Society

Gellan gum/poly (ethylene glycol) di-acrylate hydrogels with tunable mechanical properties for articular cartilage engineering

Autores: H. Al-Haddad, L. Vannozzi, D. Trucco, G. Lisignoli, L. Ricotti
Publicado en: TERMIS European Chapter Meeting, 2019
Editor: NA

A ground-breaking approach for cartilage regeneration and osteoarthritis treatment: the ADMAIORA project

Autores: Leonardo Ricotti
Publicado en: Nature Biomedical Engineering Conference, 2019
Editor: NA

3D bioprinting handheld tool concept for innovative osteoarthritis treatment with stem cells utilization

Autores: Krzysztof, Lenartowicz; Tomasz, Gapiński; Paulina, Galas; Małgorzata, Gonsior; Ricotti, Leonardo; Vannozzi, Lorenzo
Publicado en: Engineering of Biomaterials, Edición 153, 2019, Página(s) 44, ISSN 1429-7248
Editor: Polskie Stowarzyszenie Biomateriałów

Characterization of photo-crosslinkable methacrylated gellan gum hydrogels for the in situ treatment of chondral defects

Autores: Alessia Bacci, Diego Trucco, Lorenzo Vannozzi, Elena Gabusi, Enrico Lenzi, Cristina Manfredini, Liliana Agresti, Maria Rosaria Pascale, Sandra Cristino, Gina Lisignoli, Leonardo Ricotti
Publicado en: Annual Conference of the European Society for Biomaterials (ESB), 2023
Editor: ESB

Non-invasive and quantitative assessment of tissues composition based on radio-frequency ultrasound data analysis

Autores: A. Sorriento, A.Poliziani, A. Cafarelli, G.Valenza, L. Ricotti
Publicado en: Conference of the European Society for Artificial Organs (ESAO 2020), 2020
Editor: ESAO

Dose-controlled low-intensity pulsed ultrasound and pulsed electromagnetic fields stimulations modulate inflammation in human macrophages

Autores: Francesco Iacoponi, Fabio Orlando, Soria Gasparini, Tiziano Pratellesi, Andrea Cafarelli, Leonardo Ricotti
Publicado en: Proceedings of the Italian National Group of Bioengineering (GNB), 2023
Editor: GNB

Visible light-crosslinked methacrylated gellan gum hydrogels for the embedding of human chondrocytes

Autores: D. Trucco, L. Vannozzi, L. Agresti, A. Bacci, L. Riacci, G. Lisignoli and L. Ricotti
Publicado en: Biofabrication conference, 2022
Editor: Biofabrication

Highly controlled and usable system for Low-Intensity Pulsed Ultrasound Stimulation of Cells

Autores: F. Fontana, F. Iberite, L. Morchi, T. Pratellesi, A. Cafarelli, L. Ricotti
Publicado en: 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2019, Página(s) 2513-2516, ISBN 978-1-5386-1311-5
Editor: IEEE
DOI: 10.1109/embc.2019.8857772

A user-friendly solution for remote ultrasound imaging

Autores: Angela Sorriento, Giorgia Marola, Paolo Spinnato, Andrea Cafarelli, Leonardo Ricotti
Publicado en: IEEE International Ultrasonics Symposium (IUS), 2023
Editor: IEEE

Influence of substrate stiffness on human induced pluripotent stem cells: preliminary results*

Autores: F. Iberite, M. Salerno, C. Canale, A. Rosa, L. Ricotti
Publicado en: 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2019, Página(s) 1039-1043, ISBN 978-1-5386-1311-5
Editor: IEEE
DOI: 10.1109/embc.2019.8857397

Low-Intensity pulsed ultrasound stimulation enhances chondrogenic differentiation of ASCs in a 3D hydrogel

Autores: C. Manferdini, E. Gabusi, D.Trucco, P.Dolzani, Y.Saleh, A.Cafarelli, L.Ricotti,G.Lisignoli
Publicado en: STEMNET (Prima Conferenza della Federazione Associazioni Ricerca sulle Cellule Staminali), 2021
Editor: STEMNET

Primers for the adhesion of gellan gum-based hydrogels to cartilage

Autores: Laura Riacci, Diego Trucco, Lorenzo Vannozzi, Gina Lisignoli, Leonardo Ricotti
Publicado en: Materials Research Society Fall Meeting (MRS) conference, 2021
Editor: Materials Research Society

Ultrasound counteracts inflammation and induces chondrogenic differentiation of ASCs in 3D piezoelectric hydrogels

Autores: Cristina Manferdini, Elena Gabusi, Paolo Dolzani, Diego Trucco, Enrico Lenzi, Giovanni D'Atri, Lorenzo Vannozzi, Andrea Cafarelli, Leonardo Ricotti, Gina Lisignoli
Publicado en: Annual Meeting of the European Orthopaedic Research Society (EORS), 2023
Editor: EORS

Ultrasound stimulation reduces inflammation and promotes the chondrogenic differentiation of adipose mesenchymal stromal cells embedded in a 3D piezoelectric hydrogel

Autores: Enrico Lenzi, Cristina Manferdini, Elena Gabusi, Paolo Dolzani, Yasmin Saleh, Diego Trucco, Giovanni D'Atri, Marta Columbaro, Lorenzo Vannozzi, Andrea Cafarelli, Leonardo Ricotti, Gina Lisignoli
Publicado en: STEMNET meeting, 2023
Editor: STEMNET

Nano-doped piezoelectric hydrogels and low-intensity pulsed ultrasound boost the chondrogenic differentiation of human adipose tissue-derived stromal cells

Autores: L. Vannozzi, D. Trucco, C. Manferdini, A. Cafarelli, E. Gabusi, Y. Saleh, P. Dolzani, M. Columbaro, G. Lisignoli, and L. Ricotti
Publicado en: Biofabrication conference, 2022
Editor: Biofabrication

Injectable gelatin-based photocurable fiber-reinforced hydrogel for the treatment of osteochondral defects

Autores: Ignazio Niosi, Diego Trucco, Lorenzo Vannozzi, Silvia Farè, Leonardo Ricotti
Publicado en: Proceedings of the Italian National Group of Bioengineering (GNB), 2023
Editor: GNB

Biological evaluation of highly controlled low-intensity pulsed ultrasound stimulation set-ups

Autores: F. Iacoponi, F. Iberite, F. Fontana, L. Ricotti
Publicado en: Conference of the European Society for Artificial Organs (ESAO 2020), 2020
Editor: ESAO

Low-Intensity pulsed ultrasound induces chondrogenic differentiation of adipose-stromal cells in a 3D piezoelectric hydrogel

Autores: C. Manferdini, E. Gabusi, P.Dolzani, Y.Saleh, D.Trucco, E.Lenzi, M.Columbaro, L.Vannozzi, A.Cafarelli, L.Ricotti,G.Lisignoli
Publicado en: Tissue Engineering and Regenerative Medicine International Society (TERMIS) European Chapter, 2022
Editor: TERMIS

Gellan gum-based hydrogels as injectable materials for cartilage tissue engineering

Autores: L. Riacci, L. Vannozzi, L. Garcia-Hevia, L. Ricotti
Publicado en: Seventh National Congress of BioEngineering, 2020
Editor: GNB

Ultrasound stimulation of piezoelectric hydrogels boosts chondrogenic differentiation of human adipose tissue-derived stromal cells

Autores: Leonardo Ricotti, Diego Trucco, Lorenzo Vannozzi, Andrea Cafarelli, Cristina Manferdini, Elena Gabusi, Paolo Dolzani, Yasmin Saleh, Marta Columbaro, Gina Lisignoli
Publicado en: Annual Congress of the European Society for Artificial Organs (ESAO), 2022
Editor: ESAO

Development of a bilayered hydrogel with cartilage-mimicking mechanical and lubrication properties

Autores: L. Vannozzi, D. Trucco, E. Teblum, M. Telkhozhayeva, S. Affatato, G. Lisignoli, G.D. Nessim, L. Ricotti
Publicado en: Materials Research Society Fall Meeting (MRS) conference, 2020, 2020
Editor: Materials Research Society

Piezoelectric nanomaterials and ultrasound for tissue regeneration

Autores: Leonardo Ricotti
Publicado en: International Engineering in Medicine and Biology Conference (EMBC 2019), 2019
Editor: IEEE

Low-Intensity pulsed ultrasound treatments: effects on chondrogenic differentiation of adipose-stromal cells in a 3D piezoelectric hydrogel

Autores: E. Gabusi, C.Manferdini, P.Dolzani, Y.Saleh, D.Trucco, M.Columbaro, L.Vannozzi, A.Cafarelli, L.Ricotti,G.Lisignoli
Publicado en: Stem Cell Research Italy (SRC), 2022
Editor: SRC

Low-Intensity pulsed ultrasound induces chondrogenic differentiation of adipose-stromal cells in a 3D piezoelectric hydrogel

Autores: C. Manferdini, E. Gabusi, P.Dolzani, Y.Saleh, D.Trucco, M.Columbaro, L.Vannozzi, A.Cafarelli, L.Ricotti,G.Lisignoli
Publicado en: International Cartilage Regeneration & Joint Preservation Society Conference (ICRS), 2022
Editor: ICRS

Nanocomposite thin films based on polyethylene vinyl acetate and piezoelectric nanomaterials

Autores: L. Vannozzi, G. Mariotti, L. Ricotti
Publicado en: 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2019, Página(s) 1050-1053, ISBN 978-1-5386-1311-5
Editor: IEEE
DOI: 10.1109/EMBC.2019.8857556

Quantitative ultrasound assessment of healthy and degenerated cartilage

Autores: Lorena Guachi-Guachi, Angela Sorriento, Andrea Cafarelli, Paolo Dolzani, Enrico Lenzi, Gina Lisignoli, Leonardo Ricotti
Publicado en: IEEE International Ultrasonics Symposium (IUS), 2023
Editor: IEEE

Ex-vivo quantitative ultrasound assessment of cartilage degeneration

Autores: Angela Sorriento, Andrea Cafarelli, Gaetano Valenza, Leonardo Ricotti
Publicado en: 2021 43st Annual International Conference of the IEEE Engineering in Medicine and Biology Conference (EMBC), 2021
Editor: IEEE
DOI: 10.1109/embc46164.2021.9630198

3D piezoelectric hydrogel stimulated by ultrasound to counteract inflammation by stimulating chondrogenic differentiation

Autores: Cristina Manferdini, Elena Gabusi, Paolo Dolzani, Yasmin Saleh, Diego Trucco, Marta Columbaro, Lorenzo Vannozzi, Andrea Cafarelli, Leonardo Ricotti, Gina Lisignoli
Publicado en: International Cartilage Regeneration & Joint Preservation Society conference (ICRS), 2023
Editor: ICRS

Low-Intensity pulsed ultrasound stimulation enhances chondrogenic differentiation of ASCs in a 3D hydrogel

Autores: C. Manferdini, E. Gabusi, D. Trucco, P. Dolzani, Y. Saleh, A. Cafarelli, L. Ricotti, G. Lisignoli
Publicado en: European Society of Biomaterials (ESB) conference (2021), 2021
Editor: European Society of Biomaterials (ESB)

Dose-controlled low-intensity pulsed ultrasound to modulate the inflammatory response

Autores: F. Iacoponi, F. Fontana, E. Catalano, C. Manferdini, D. Trucco, A. Cafarelli, G. Lisignoli, L. Ricotti
Publicado en: Tissue Engineering and Regenerative Medicine International Society (TERMIS) conference, 2021
Editor: Tissue Engineering and Regenerative Medicine International Society

Low-intensity pulsed ultrasound is effective in counteracting inflammation and inducing chondrogenic differentiation of adipose-stromal cells in 3d piezoelectric hydrogels

Nano-doped piezoelectric hydrogels and low-intensity pulsed ultrasound boost the chondrogenic differentiation of human adipose tissue-derived stromal cells

Autores: Leonardo Ricotti, Diego Trucco, Lorenzo Vannozzi, Andrea Cafarelli, Cristina Manferdini, Elena Gabusi, Paolo Dolzani, Yasmin Saleh, Marta Columbaro, Gina Lisignoli
Publicado en: Annual Conference of the European Society of Biomaterials (ESB), 2022
Editor: ESB

Injectable Hydrogels Reinforced with Structures obtained through Melt Electrowriting

Autores: Diego Trucco, Rory Kibney, Lorenzo Vannozzi, Gina Lisignoli, Daniel J. Kelly, Leonardo Ricotti
Publicado en: Annual Conference of the European Society for Biomaterials (2023), 2023
Editor: ESB

Low-Intensity pulsed ultrasound induces chondrogenic differentiation of adipose-stromal cells in a 3D piezoelectric hydrogel

Autores: C. Manferdini, E. Gabusi, P.Dolzani, Y.Saleh, D.Trucco, M.Columbaro, L.Vannozzi, A.Cafarelli, L.Ricotti,G.Lisignoli
Publicado en: World Congress on Osteoarthritis (OARSI), 2022
Editor: OARSI